Search results for "Microelectronics"

showing 10 items of 234 documents

cIAP1 regulates TNF-mediated cdc42 activation and filopodia formation

2013

International audience; umour necrosis factor-α (TNF) is a cytokine endowed with multiple functions, depending on the cellular and environmental context. TNF receptor engagement induces the formation of a multimolecular complex including the TNFR-associated factor TRAF2, the receptor-interaction protein kinase RIP1 and the cellular inhibitor of apoptosis cIAP1, the latter being essential for NF-κB activation. Here, we show that cIAP1 also regulates TNF-induced actin cytoskeleton reorganization through a cdc42-dependent, NF-κB-independent pathway. Deletion of cIAP1 prevents TNF-induced filopodia and cdc42 activation. The expression of cIAP1 or its E3-ubiquitin ligase-defective mutant restore…

Cancer ResearchLung NeoplasmsBlotting WesternFluorescent Antibody Techniquemacromolecular substancesCDC42BiologyTransfectionInhibitor of Apoptosis ProteinsMice03 medical and health sciences0302 clinical medicineCell AdhesionGeneticsAnimalsHumansImmunoprecipitationNeoplasm InvasivenessPseudopodia[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronicscdc42 GTP-Binding ProteinMolecular Biology030304 developmental biology0303 health sciencesTumor Necrosis Factor-alphaActin cytoskeleton reorganizationCell PolarityActin remodelingSurface Plasmon ResonanceActin cytoskeletonCell biologyActin CytoskeletonDisease Models AnimalHEK293 CellsCdc42 GTP-Binding Protein030220 oncology & carcinogenesisNIH 3T3 CellsHeterografts[ SPI.NANO ] Engineering Sciences [physics]/Micro and nanotechnologies/MicroelectronicsPseudopodiaSignal transductionFilopodiaSignal TransductionOncogene
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Observation of topological gravity-capillary waves in a water wave crystal

2019

The discovery of topological phases of matter, initially driven by theoretical advances in quantum condensed matter physics, has been recently extended to classical wave systems, reaching out to a wealth of novel potential applications in signal manipulation and energy concentration. Despite the fact that many realistic wave media (metals at optical frequencies, polymers at ultrasonic frequencies) are inherently dispersive, topological wave transport in photonic and phononic crystals has so far been limited to ideal situations and proof-of-concept experiments involving dispersionless media. Here, we report the first experimental demonstration of topological edge states in a classical water …

Capillary waveWave propagationFOS: Physical sciencesGeneral Physics and AstronomyInsulator (electricity)Topology01 natural sciences010305 fluids & plasmas[SPI.MAT]Engineering Sciences [physics]/MaterialsMesoscale and Nanoscale Physics (cond-mat.mes-hall)0103 physical sciences[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics010306 general physicsDispersion (water waves)QuantumPhysics[SPI.ACOU]Engineering Sciences [physics]/Acoustics [physics.class-ph]Condensed Matter - Mesoscale and Nanoscale Physicsbusiness.industryFluid Dynamics (physics.flu-dyn)Valley PhysicsPhysics - Fluid DynamicsTopological InsulatorsWater wavesTopological insulatorUltrasonic sensorPhotonicsbusiness
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Surface-plasmon hopping along coupled coplanar cavities

2007

International audience; We report on surface-plasmon propagation along coupled coplanar cavities periodically distributed in an otherwise unperturbed plasmonic crystal. We show that the dispersion of particular Bloch modes can exhibit multiple energy gaps that can be adjusted by choosing the cavity size. For resonant sizes, the composite crystals composed of juxtaposed cavities can support plasmon modes at frequencies within the gap of the unperturbed grating. In this case, we demonstrate that the surface-plasmon propagation relies on a hopping mechanism.

Cavity sizePhysics::Optics02 engineering and technologyGrating01 natural sciencesMolecular physicsCrystalOptics0103 physical sciencesDispersion (optics)[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics010306 general physicsComputer Science::DatabasesPlasmonPhysics[PHYS.PHYS.PHYS-OPTICS]Physics [physics]/Physics [physics]/Optics [physics.optics][ PHYS.PHYS.PHYS-OPTICS ] Physics [physics]/Physics [physics]/Optics [physics.optics]business.industrySurface plasmon021001 nanoscience & nanotechnologyCondensed Matter PhysicsElectronic Optical and Magnetic Materials[SPI.OPTI]Engineering Sciences [physics]/Optics / PhotonicQuasiparticle[ SPI.NANO ] Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics[ SPI.OPTI ] Engineering Sciences [physics]/Optics / Photonic0210 nano-technologybusinessPhysical Review B
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Simulations of a Graphene Nanoflake as a Nanovector To Improve ZnPc Phototherapy Toxicity: From Vacuum to Cell Membrane

2017

International audience; We propose a new approach to improving photodynamic therapy (PDT) by transporting zinc phthalocyanine (ZnPc) in biological systems via a graphene nanoflake, to increase its targeting. Indeed, by means of time-dependent density functional theory simulations, we show that the ZnPc molecule in interaction with a graphene nanoflake preserves its optical properties not only in a vacuum but also in water. Moreover, molecular dynamic simulations demonstrate that the graphene nanoflake/ZnPc association, as a carrier, permits one to stabilize the ZnPc/graphene nanoflake system on the cellular membrane, which was not possible when using ZnPc alone. We finally conclude that the…

Cellular membraneIndolesMaterials scienceVacuum[SPI.NANO] Engineering Sciences [physics]/Micro and nanotechnologies/MicroelectronicsNanotechnology02 engineering and technology[SPI.MAT] Engineering Sciences [physics]/Materials010402 general chemistry01 natural sciences[SPI.MAT]Engineering Sciences [physics]/Materialslaw.inventionCell membraneMolecular dynamicslawCell Line TumorOrganometallic CompoundsmedicineHumansMoleculeGeneral Materials Science[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics[SPI.ACOU]Engineering Sciences [physics]/Acoustics [physics.class-ph]Zinc phthalocyanine[SPI.ACOU] Engineering Sciences [physics]/Acoustics [physics.class-ph]Photosensitizing AgentsGrapheneCell Membrane021001 nanoscience & nanotechnologyNanostructures0104 chemical sciencesmedicine.anatomical_structurePhotochemotherapyGraphiteDensity functional theory0210 nano-technology
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First Steps of µTAS in Latvia

1995

Owing to participation of Latvian and Swedish scientists in the field of chemically sensitive FET and MOS structures it was possible to utilize the technological facilities of the Microelectronics enterprise in Latvia in making an integrated smart sensor as a matrix of chemically sensitive FETs by using silicon based microtechnology. Thereby the first steps of µTAS in Latvia are made in the direction of integration of solid state ionic materials with FET and MOS structures to develop new chemically sensitive structures and systems.

Computer scienceCatalytic metalbusiness.industrySolid-stateMicrotechnologyMicroelectronicsNanotechnologybusinessAmmonia vaporSilicon based
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Unsupervised image processing scheme for transistor photon emission analysis in order to identify defect location

2015

International audience; The study of the light emitted by transistors in a highly scaled complementary metal oxide semiconductor (CMOS) integrated circuit (IC) has become a key method with which to analyze faulty devices, track the failure root cause, and have candidate locations for where to start the physical analysis. The localization of defective areas in IC corresponds to a reliability check and gives information to the designer to improve the IC design. The scaling of CMOS leads to an increase in the number of active nodes inside the acquisition area. There are also more differences between the spot’s intensities. In order to improve the identification of all of the photon emission sp…

Computer scienceImage processing[ SPI.SIGNAL ] Engineering Sciences [physics]/Signal and Image processing02 engineering and technologyIntegrated circuitIntegrated circuit design01 natural scienceslaw.inventionlaw0103 physical sciences0202 electrical engineering electronic engineering information engineeringComputer visionElectrical and Electronic Engineering[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics010302 applied physicsSignal processingNoise (signal processing)business.industryPattern recognitionImage segmentationThresholdingAtomic and Molecular Physics and OpticsComputer Science ApplicationsCMOS[ SPI.NANO ] Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics020201 artificial intelligence & image processingArtificial intelligencebusiness[SPI.SIGNAL]Engineering Sciences [physics]/Signal and Image processing
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High-order modes in cavity-resonator-integrated guided-mode resonance filters (CRIGFs)

2015

International audience; Cavity-resonator-integrated guided-mode resonance filters (CRIGFs) are optical filters based on weak coupling by a grating between a free-space propagating optical mode and a guided mode, like guided-mode resonance filters (GMRFs). As compared to GMRFs they offer narrowband reflection with small aperture and high angular acceptance. We report experimental characterization and theoretical modeling of unexpected high-order reflected modes in such devices. Using coupled-mode modeling and moiré analysis we provide physical insight on key mechanisms ruling CRIGF properties. This model could serve as a simple and efficient framework to design new reflectors with tailored s…

CouplingPhysicsGuided-mode resonancebusiness.industryResonanceGratingCoupled mode theoryAtomic and Molecular Physics and OpticsElectronic Optical and Magnetic MaterialsResonatorNarrowbandOptics[SPI.OPTI]Engineering Sciences [physics]/Optics / PhotonicComputer Vision and Pattern Recognition[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/MicroelectronicsOptical filterbusiness
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Acousto-optic cavity coupling in 2D phoxonic crystal with combined convex and concave holes

2021

International audience; A two-dimensional cross-like phoxonic crystal (PxC) model is proposed, which exhibits simultaneously large complete photonic crystal (PtC) and phononic crystal (PnC) bandgaps. The most salient trait of the structure is the wide range of geometrical parameters compatible with large complete bandgaps. After geometrical optimization, photonic and phononic bandgaps with gap-to-midgap ratios of 11.5% and 90.7% are obtained, respectively. These values are close to the best topology-optimized reported values but are obtained with simple shapes compatible with nanoscale fabrication technology. These characteristics make the convex–concave topology a promising candidate for P…

CouplingPhysics[SPI.ACOU]Engineering Sciences [physics]/Acoustics [physics.class-ph]PhotonCondensed matter physicsPhononbusiness.industryGeneral Physics and AstronomyPhysics::Optics02 engineering and technology021001 nanoscience & nanotechnology01 natural sciencesFinite element method[SPI.MAT]Engineering Sciences [physics]/MaterialsCrystalSuperposition principle0103 physical sciencesPhotonics[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics010306 general physics0210 nano-technologybusinessPhotonic crystal
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Enhanced nanoscopy of individual CsPbBr3 perovskite nanocrystals using dielectric sub-micrometric antennas

2020

We demonstrate an efficient, simple, and low-cost approach for enhanced nanoscopy in individual green emitting perovskite (CsPbBr3) nanocrystals via TiO2 dielectric nanoantenna. The observed three- to five-fold emission enhancement is attributed to near-field effects and emission steering promoted by the coupling between the perovskite nanocrystals and the dielectric sub-micrometric antennas. The dark-field scattering configuration is then exploited for surface-enhanced absorption measurements, showing a large increase in detection sensitivity, leading to the detection of individual nanocrystals. Due to the broadband spectral response of the Mie sub-micrometric antennas, the method can be e…

Detection sensitivityMaterials sciencelcsh:BiotechnologyCesium compoundsPhysics::Optics02 engineering and technologyDielectricPerovskiteLead compoundsperovskite solar cells01 natural sciences7. Clean energyCondensed Matter::Materials Sciencenanocrystalslcsh:TP248.13-248.650103 physical sciencesEnhanced absorptionSemiconductor quantum dotsElectronic transitionGeneral Materials Science[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/MicroelectronicsAbsorption (electromagnetic radiation)perovskitePerovskite (structure)010302 applied physicsScatteringbusiness.industryGeneral Engineering021001 nanoscience & nanotechnologylcsh:QC1-999NanocrystalsNear field effectNanocrystalAtomic electron transitionQuantum dotOptoelectronicsTitanium dioxideAntennasDark-field scatteringsLow cost approachPhotonics0210 nano-technologybusinessOrganic moleculeslcsh:PhysicsBromine compoundsEmission enhancement
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Experimental realization of a pillared metasurface for flexural wave focusing

2021

International audience; A metasurface is an array of subwavelength units with modulated wave responses that show great potential for the control of refractive/reflective properties in compact functional devices. In this work, we propose an elastic metasurface consisting of a line of pillars with gradient heights, erected on a homogeneous plate. The change in the resonant frequencies associated with the height gradient allows us to achieve transmitted phase response covering a range of 2π, while the amplitude response remains at a relatively high level. We employ the pillared units to design a focusing metasurface and compare the properties of the focal spots through simulation and experimen…

DiffractionMaterials scienceFabricationQC1-999Physics::Optics02 engineering and technologyInterference (wave propagation)01 natural sciences[SPI.MAT]Engineering Sciences [physics]/MaterialsOpticsRobustness (computer science)0103 physical sciencesPhase responseFocal lengthGeneral Materials Science[SPI.NANO]Engineering Sciences [physics]/Micro and nanotechnologies/Microelectronics010302 applied physics[SPI.ACOU]Engineering Sciences [physics]/Acoustics [physics.class-ph]business.industryPhysicsGeneral Engineering021001 nanoscience & nanotechnologyTransverse planeFull width at half maximum0210 nano-technologybusinessTP248.13-248.65Biotechnology
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