Search results for "Minimum inhibitory concentration"

showing 10 items of 61 documents

Tetrahydroanthraquinone Derivatives from the Endophytic Fungus Stemphylium globuliferm

2015

Four new tetrahydroanthraquinone derivatives, namely, dihydroaltersolanol B (1), dihydroaltersolanol C (2), and the atropisomers acetylalterporriol D (3) and acetylalterporriol E (4), were obtained from the endophytic fungus Stemphylium globuliferum, which was isolated from Juncus acutus growing in Egypt. The structures of the new compounds were unambiguously elucidated on the basis of one- and two-dimensional NMR spectroscopy, as well as by high-resolution mass spectrometry and electronic circular dichroism (ECD) spectroscopy. In addition, seven known anthraquinone derivatives 5–11 were isolated and identified on the basis of their spectral characteristics and by comparison with literature…

Circular dichroismbiologyChemistryStereochemistryOrganic ChemistryNuclear magnetic resonance spectroscopymedicine.disease_causebiology.organism_classificationPlant use of endophytic fungi in defenseMinimum inhibitory concentrationStemphylium globuliferumTermészettudományokJuncus acutusmedicinePhysical and Theoretical ChemistryAntibacterial activityKémiai tudományokEscherichia coli
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Comparison of the activity of antifungal hexapeptides and the fungicides thiabendazole and imazalil against postharvest fungal pathogens

2003

8 pages, 2 figures, 3 tables.-- PMID: 14623382 [PubMed].-- Printed version published Dec 31, 2003.

CitrusAntimicrobial peptidesCitrus fruitsMicrobial Sensitivity TestsMicrobiologyMicrobiologyMinimum inhibitory concentrationRhizopusFood PreservationThiabendazolePostharvestFungicidesPenicillium digitatumDose-Response Relationship DrugbiologyImidazolesPenicilliumfood and beveragesGeneral MedicineAlternariabiology.organism_classificationAntimicrobialFungicides IndustrialFungicideFruitPenicilliumAntimicrobial peptidesOligopeptidesFood ScienceInternational Journal of Food Microbiology
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In vitro activities of antimicrobial agents against Candida species

1999

Objective. Antimicrobial mouthrinses may represent a valid alternative to topical antifungal agents. However, the action of antimicrobials could be affected by the different ingredients incorporated into mouthrinse products. The purpose of the present study was to investigate the in vitro antifungal and fungicidal activities of antimicrobials alone. Study Design. A broth macrodilution method was used to determine the minimum inhibitory concentration of 4 antimicrobial agents against Candida species. Minimum fungicidal concentration was also determined. Results. All antimicrobials showed antifungal activity against all tested organisms, but cetylpyridinium chloride received significantly low…

DrugAntifungal Agentsmedia_common.quotation_subjectColony Count MicrobialMouthwashesCetylpyridiniumMicrobial Sensitivity TestsHexetidineBiologyCetylpyridinium chlorideStatistics NonparametricMicrobiologychemistry.chemical_compoundMinimum inhibitory concentrationAlkaloidsmedicineGeneral DentistryMycosisCandidamedia_commonBenzophenanthridinesAnalysis of VarianceDose-Response Relationship DrugTraditional medicineChlorhexidineHexetidineFungi imperfectiIsoquinolinesmedicine.diseasebiology.organism_classificationAntimicrobialFungicideOtorhinolaryngologychemistryAnti-Infective Agents LocalSurgeryOral SurgeryOral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology
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Evaluation of antifungal activity of three essential oils against selected isolates of Penicillium, Purpureocillium and Acremonium

2018

Storage is a critical process of food production because incorrect conditions during this process lead to the growth of economic costs caused by material loss. It is important to maintain adequate microbiological purity of storage areas. The development of microbes present in warehouses may lead to secondary contamination of stored materials and reduce their quality. The aim of the study was to evaluate the effect of essential oils on the growth of Acremonium strictum , Penicillium citrinum, Penicillium expansum and Purpureocillium lilacinum . Fungal strains were isolated from the food warehouse. Studies on the influence of selected mix of phenolic substances were performed using three comm…

EcologybiologyAcremoniumEcological ModelingGeography Planning and DevelopmentAcremonium strictumbiology.organism_classificationFungicidechemistry.chemical_compoundPurpureocillium lilacinumMinimum inhibitory concentrationchemistryPenicilliumPenicillium citrinumFood sciencePenicillium expansumEcology Evolution Behavior and SystematicsEcological Questions
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Control of food spoilage fungi by ethanol

2011

This review discusses the effects of ethanol on the inhibition of growth and germination of fungi and on the inactivation of fungal spores. After a brief survey on the impact of spoilage fungi on the economy and food quality, the major applications of ethanol in controlling fruit decay and extending the shelf-life of food products are reviewed. Many parameters including minimum inhibitory concentration (MIC) and D-values for various moulds are included. The thermodynamic relationship between the liquid phase and the headspace and the mode of action of ethanol on fungi are explained. Due to their promising use as a fumigant, special attention is paid to ethanol vapours.

EthanolfungiFood spoilageBiologymedicine.diseaseSporeConidiumMinimum inhibitory concentrationchemistry.chemical_compoundchemistryGerminationmedicineFood scienceFood qualityVapoursFood ScienceBiotechnologyFood Control
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Susceptibility and resistance to ethanol in Saccharomyces strains isolated from wild and fermentative environments

2010

11 pages, 3 figures, 3 tables.-- Article first published online: 8 SEP 2010

Gompertz functionWineBioengineeringEthanol toleranceBiologyApplied Microbiology and BiotechnologyBiochemistrySaccharomycesParadoxusSaccharomyceschemistry.chemical_compoundMinimum inhibitory concentrationDrug Resistance FungalBotanyEnvironmental MicrobiologyGeneticsFood scienceAdaptationStatistical modellingEthanolEthanolbiology.organism_classificationYeastOleic acidchemistryFermentationFermentationBiotechnologyYeast
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Capacity of Gentamicin-Treated Pseudomonas aeruginosa to Induce Granulocyte Locomotion

1982

In protection against an invading parasite the host’s granulocytes play an essential role. To exert their defense the phagocytes have to be attracted to the site of parasite invasion. We have shown that Pseudomonas aeruginosa ATCC 27853 and other clinical isolates of this species can induce granulocyte migration, either directly or via generation of chemotactic activity in serum [1].

Granulocyte migrationPseudomonas aeruginosaChemistryChemotaxisBoyden chamberGranulocytemedicine.disease_causeMicrobiologyMinimum inhibitory concentrationmedicine.anatomical_structuremedicineParasite hostingGentamicinmedicine.drug
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Constituents of leaves and flowers essential oils of Helichrysum pallasii (Spreng.) Ledeb. growing wild in Lebanon.

2009

The chemical compositions of the essential oils obtained from leaves and flowers of Helichrysum pallasii were analyzed by gas chromatography and gas chromatography-mass spectrometry. Among the 102 identified constituents, hexadecanoic acid (16.2%), (Z,Z)-9,12-octadecadienoic acid (6.8%), tetradecanoic acid (2.6%), and (Z)-caryophyllene (4.2%) were the main constituent of the oil from leaves, while in the oil from flowers hexadecanoic acid (14.7%), (Z,Z)-9,12-octadecadienoic acid (14.2%), (Z)-caryophyllene (3.6%), and delta-cadinene (3.1%) predominated. The oils were both characterized by sesquiterpenes (33.4% for leaves and 33.7% for flowers, respectively) and fatty acids and esters (30.3% …

Helichrysum pallasii (Spreng.) Ledeb.Palmitic AcidMedicine (miscellaneous)Myristic acidFlowersMyristic Acidlaw.inventionPalmitic acidMinimum inhibitory concentrationchemistry.chemical_compoundlawBotanyOils VolatileStaphylococcus epidermidisPlant OilsFood scienceLebanonEssential oilHelichrysumPolycyclic SesquiterpenesNutrition and DieteticsbiologyBacteriaPlant ExtractsAnti-Inflammatory Agents Non-SteroidalFatty AcidsEstersAsteraceaebiology.organism_classificationAnti-Bacterial AgentsPlant LeaveschemistryHelichrysumFatty Acids UnsaturatedStearic acidGas chromatographySesquiterpenesJournal of medicinal food
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Biological Responses of <I>Rhynchophorus ferrugineus</I> (Coleoptera: Curculionidae) to <I>Steinernema carpocapsae</I> (Nemat…

2013

Rhynchophorus ferrugineus (Olivier 1790) (Coleoptera: Curculionidae) is becoming a serious problem in Mediterranean areas where it is well-adapted, and now is present even in the United States (California). The infestations are primarily in urban areas where chemical control is not advisable and million of Euros are spent to control it. The effects of the entomopathogenic nematode Steinernema carpocapsae (Nematoda: Steinernematidae) on mortality, growth, as well as the immune activity of R. ferrugineus larvae, were investigated. R. ferrugineus mortality exhibited a positive trend with the dosage and duration of exposure to S. carpocapsae. The median lethal dose and median lethal time, impor…

LarvaVeterinary medicineEcologybiologyBiological pest controlXenorhabdusGeneral MedicineEntomopathogenic nematodebiology.organism_classificationMedian lethal doseToxicologyRhynchophorusMinimum inhibitory concentrationInsect ScienceCurculionidaeJournal of Economic Entomology
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DALI: Defining Antibiotic Levels in Intensive Care Unit Patients: Are Current -Lactam Antibiotic Doses Sufficient for Critically Ill Patients?

2014

Background. Morbidity and mortality for critically ill patients with infections remains a global healthcare problem. We aimed to determine whether α-lactam antibiotic dosing in critically ill patients achieves concentrations associated with maximal activity and whether antibiotic concentrations affect patient outcome.Methods. This was a prospective, multinational pharmacokinetic point-prevalence study including 8 α-lactam antibiotics. Two blood samples were taken from each patient during a single dosing interval. The primary pharmacokinetic/pharmacodynamic targets were free antibiotic concentrations above the minimum inhibitory concentration (MIC) of the pathogen at both 50% (50% f TMIC) an…

MaleInternational CooperationAntibioticsadverse eventintensive care unitlaw.invention0302 clinical medicinemeropenemModels[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseasesadverse events; continuous infusion; extended infusion; pharmacodynamics; pharmacokinetics; Aged; Anti-Bacterial Agents; Bacterial Infections; Blood Chemical Analysis; Female; Humans; Intensive Care Units; International Cooperation; Male; Microbial Sensitivity Tests; Middle Aged; Models Statistical; Prospective Studies; Treatment Outcome; beta-Lactams; Critical Illnessantibiotic therapyProspective Studiesamoxicillin plus clavulanic acidComputingMilieux_MISCELLANEOUSbeta lactam antibioticAPACHE0303 health sciencescritical illneadultclinical trial3. Good healthcontinuous infusion; extended infusion; adverse events; pharmacokinetics; pharmacodynamics.antiinfective agent[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitologypriority journaldisease severitybeta-Lactamstatistical model Agedprospective studyHumanMicrobiology (medical)medicine.medical_specialtydrug exposureCritical IllnessImmunologybloodstream infectionMicrobial Sensitivity Testspiperacillin plus tazobactambeta-LactamsMicrobiologybeta lactam abdominal infection03 medical and health sciencescritically ill patientIntensive careAnti-Bacterial AgentcefepimepharmacodynamicsHumansDosingAdverse effectAgedModels Statistical030306 microbiologyOdds ratiomajor clinical studymortalityantibiotic sensitivityceftriaxoneProspective Studiemulticenter studypharmacodynamics.ampicillinBlood Chemical AnalysisCeftazidimeSettore MED/41 - AnestesiologiaInterquartile rangelaw030212 general & internal medicinepharmacokineticlung infectionMicrobial Sensitivity TestarticleBacterial InfectionsMiddle AgedStatisticalcontinuous infusionIntensive care unitAnti-Bacterial Agentsextended infusionIntensive Care UnitsInfectious DiseasesTreatment Outcomeadverse events; continuous infusion; extended infusion; pharmacodynamics; pharmacokinetics; Aged; Anti-Bacterial Agents; Bacterial Infections; Blood Chemical Analysis; Female; Humans; Intensive Care Units; International Cooperation; Male; Microbial Sensitivity Tests; Middle Aged; Models Statistical; Prospective Studies; Treatment Outcome; beta-Lactams; Critical Illness; Microbiology (medical); Infectious Diseasescefazolin[SDV.IMM]Life Sciences [q-bio]/Immunologyblood samplingFemalepharmacokineticsmedicine.drugmedicine.drug_classprevalencedoripenemminimum inhibitory concentrationBacterial InfectionInternal medicinemedicinecontrolled studyblood analysibusiness.industryBlood Chemical Analysiadverse eventsSurgerypharmacodynamicdrug blood levelbusiness
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