Search results for "Multicenter study"
showing 10 items of 211 documents
Report on the second EDNAP collaborative STR exercise
1995
This report describes an inter-laboratory exercise completed on behalf of the European DNA Profiling (EDNAP) group. The exercise is one in a series designed to identify STR loci which could be used for harmonisation between participating European forensic science laboratories. Participants were asked to identify the alleles present in five bloodstains at the STR loci HUMTHO1 and HUMVWFA31/A. Two of the stains were prepared from mixtures of two different blood samples. There were no special instructions and each laboratory was requested to use the methodology normally employed for crime case investigations. All participating laboratories achieved the same results for both loci. In addition, …
The activities and participation categories of the ICF Core Sets for multiple sclerosis from the patient perspective.
2013
Purpose: To validate the activities and participation components of The International Classification of Functioning, Disability and Health (ICF). Methods: In this cross-sectional study, 113 Finnish community-dwelling persons with MS were assessed using a semi-structured interview provided by the Canadian Occupational Performance Measure (COPM) to capture participants’ self-perceived problems in everyday activities and participation. Problems were linked to the ICF categories. Results: Participants identified 527 of the most important occupational performance problems. They covered all chapters of the ICF Activities and Participation components. Forty-one categories out of a total 53 ICF act…
Effects of high-intensity training on physiological and hormonal adaptions in well-trained cyclists
2017
Purpose: This study aimed to compare the effects of three different high-intensity training (HIT) models, balanced for total load but differing in training plan progression, on endurance adaptations. Methods: Sixty-three cyclists (peak oxygen uptake (V˙ O2peak) 61.3 T 5.8 mLIkgj1 Iminj1 ) were randomized to three training groups and instructed to follow a 12-wk training program consisting of 24 interval sessions, a high volume of low-intensity training, and laboratory testing. The increasing HIT group (n = 23) performed interval training as 4 16 min in weeks 1–4, 4 8 min in weeks 5–8, and 4 4 min in weeks 9–12. The decreasing HIT group (n = 20) performed interval sessions in the opposite me…
A way to screen for suffering in palliative care
1997
We report a new tool for screening the suffering of terminally ill patients in a palliative care service. We systematically asked 371 terminal oncological and AIDS patients on 665 different occasions, “How long did yesterday seem to you?”; we then asked them to assess their current condition. The simple answer about subjective length of time correlated well with subjective suffering in approximately half the patients. Thus it may be a good starting point for future assessment and more extensive explorations.
High-urgency kidney transplantation in the Eurotransplant Kidney Allocation System : success or waste of organs? The Eurotransplant 15-year all-centr…
2016
Item does not contain fulltext BACKGROUND: In the Eurotransplant Kidney Allocation System (ETKAS), transplant candidates can be considered for high-urgency (HU) status in case of life-threatening inability to undergo renal replacement therapy. Data on the outcomes of HU transplantation are sparse and the benefit is controversial. METHODS: We systematically analysed data from 898 ET HU kidney transplant recipients from 61 transplant centres between 1996 and 2010 and investigated the 5-year patient and graft outcomes and differences between relevant subgroups. RESULTS: Kidney recipients with an HU status were younger (median 43 versus 55 years) and spent less time on the waiting list compared…
Quantifying Excess Deaths Related to Heatwaves under Climate Change Scenarios: A multicountry time series modelling study
2018
Background: Heatwaves are a critical public health problem. There will be an increase in the frequency and severity of heatwaves under changing climate. However, evidence about the impacts of climate change on heatwave-related mortality at a global scale is limited. Methods and findings: We collected historical daily time series of mean temperature and mortality for all causes or nonexternal causes, in periods ranging from January 1, 1984, to December 31, 2015, in 412 communities within 20 countries/regions. We estimated heatwave–mortality associations through a two-stage time series design. Current and future daily mean temperature series were projected under four scenarios of greenhouse g…
Transanal coloanal anastomosis for Hirschsprung's disease: comparison between endorectal and perirectal pull-through procedures.
2006
Le but de cette etude est de comparer les resultats de 2 techniques chirurgicales d'abaissement transanal par voie perineale pour maladie de Hirschsprung de forme recto-sigmoidienne. Materiel et Methode: Vingt-et-un patients porteurs de maladie de Hirschsprung de forme recto-sigmoidienne ont ete consecutivement operes entre novembre 1999 et avril 2003 dans les services de Chirurgie Pediatrique de Dijon et Strasbourg. Les 21 enfants ont ete operes par voie perineale transanale: Douze d'entre eux ont eu une dissection peri-rectale (TPR) et 9 une endorectale type Soave (TER). Les 2 groupes de patients ont ete compares pour la longueur du segment aganglionnaire, l'âge et le poids au moment de l…
Le risque d’intubation des grands prématurés en salle de naissance est-il lié au type d’anesthésie maternelle ? Expérience des réseaux périnatals Poi…
2009
Resume Objectif Apprecier le taux d’intubation en salle de naissance des grands prematures nes par cesarienne avant travail, en fonction du type d’anesthesie maternelle (rachianesthesie versus anesthesie generale [AG]). Population et methode Deux cent dix-neuf grands prematures (28–32 semaines d’amenorrhee) nes vivants par cesarienne avant travail dans une des 27 maternites de 2 reseaux perinatals (Poitou-Charentes et Franche-Comte). Cent quatre-vingt-deux sur 219 (83 %) sont nes dans la maternite regionale de reference de type III. Resultats Parmi les grands prematures (73/219), 33,3 % ont beneficie d’une intubation en salle de naissance, quelle qu’en soit l’indication (mauvaise adaptation…
Wie wirksam ist psychosomatische Therapie bei somatoformen Störungen? Ergebnisse einer Multicenterstudie
2014
Zusammenfassung Fragestellung: Ziel der Arbeit ist die Beschreibung von Behandlungseffekten bei somatoformen Storungen durch stationare Psychotherapie aufgrund von Patienten- und Therapeutenbeurteilung. Methode: 2 062 Patienten mit der Primardiagnose F45.XX (ICD-10, Somatoforme Storungen) wurden in 17 bayrischen Psychosomatischen Kliniken behandelt. Es wurden vier Subgruppen (F45.0X, F45.3X, F45.4X, sonstige F45.XX) gebildet.Ergebnisse: Die Symptomschwere verringerte sich in allenUntergruppen. Die Pra-Post-Effektstarke betrug d = -.58 beim Global Severity Index der SCL-90-R (GSI) und -1.26 beim Beeintrachtigungs- Schwere-Score (BSS). Untergruppen der somatoformen Storungen unterschieden sic…
Riesgo cardiovascular en sujetos con alta probabilidad de síndrome metabólico y resistencia a la insulina. Estudio DESIRE
2008
Introduccion y objetivos El sindrome metabolico agrupa alteraciones estrechamente relacionadas. El objetivo principal de este estudio es conocer la frecuencia del sindrome metabolico y de la resistencia a la insulina, y su papel como indicadores de riesgo cardiovascular en poblacion adulta asignada a consultas de Atencion Primaria en Espana. Metodos Sujetos ≥ 45 anos con glucemia basal ≥ 90 mg/dl y perimetro de cintura ≥ 94 cm (hombres) u 80 cm (mujeres). Se utilizaron los criterios del ATP III modificados para identificar el sindrome metabolico y el indice HOMA > 3,29 para la resistencia a la insulina. El riesgo cardiovascular se estimo mediante los modelos Framingham y SCORE. Resultados S…