Search results for "Must"
showing 10 items of 340 documents
Comparative genomics and proteomics of Helicobacter mustelae, an ulcerogenic and carcinogenic gastric pathogen
2010
Abstract Background Helicobacter mustelae causes gastritis, ulcers and gastric cancer in ferrets and other mustelids. H. mustelae remains the only helicobacter other than H. pylori that causes gastric ulceration and cancer in its natural host. To improve understanding of H. mustelae pathogenesis, and the ulcerogenic and carcinogenic potential of helicobacters in general, we sequenced the H. mustelae genome, and identified 425 expressed proteins in the envelope and cytosolic proteome. Results The H. mustelae genome lacks orthologs of major H. pylori virulence factors including CagA, VacA, BabA, SabA and OipA. However, it encodes ten autotransporter surface proteins, seven of which were detec…
Update of the distribution and habitat use of the wildcat, pine marten and weasel in Sicily
2020
The wildcat (Felis silvestris), the pine marten (Martes martes) and the weasel (Mustela nivalis) are key members of the mammalian community in Sicily, actually performing the role of top predators and consequently influencing the trophic chain both in natural and agricultural areas. However, despite their protected status, very little information is available regarding their occurrence and ecology. Here, by verifying published studies, collecting personal observations and analyzing novel field data obtained by camera traps, we update their spatial distribution in Sicily, contributing to a better understanding of their habitat use and suggesting future research to improve our knowledge of th…
Eduskunnan avoin data ja tieteentekijöiden yhteiskunnallinen vaikuttavuus
2023
Organic material dissolved during oxygen-alkali pulping of hot-water-extracted spruce sawdust
2016
Untreated and hot-water-extracted (HWE) Norway spruce (Picea abies) sawdust was cooked using the sulfur-free oxygen-alkali (OA) method under the following conditions: temperature, 170 °C; liquor-to-wood ratio, 5:1 L/kg; and NaOH charge, 19% on the oven-dry sawdust. In comparison with earlier studies conducted with birch sawdust, the spruce cooking yield data, together with the amount of the pulp rejects (78% to 86% for reference pulps from the initial feedstock and 73% to 83% for pulps from the HWE feedstock), revealed that the pretreatment stage prior to spruce OA pulping caused different effects on pulping performance. The analyses of the three main compound groups (i.e., lignin, volatile…
Introducing Traceability in GitHub for Medical Software Development
2021
Assuring traceability from requirements to implementation is a key element when developing safety critical software systems. Traditionally, this traceability is ensured by a waterfall-like process, where phases follow each other, and tracing between different phases can be managed. However, new software development paradigms, such as continuous software engineering and DevOps, which encourage a steady stream of new features, committed by developers in a seemingly uncontrolled fashion in terms of former phasing, challenge this view. In this paper, we introduce our approach that adds traceability capabilities to GitHub, so that the developers can act like they normally do in GitHub context bu…
Can visualization alleviate dichotomous thinking? Effects of visual representations on the cliff effect
2021
Common reporting styles for statistical results in scientific articles, such as $p$ p -values and confidence intervals (CI), have been reported to be prone to dichotomous interpretations, especially with respect to the null hypothesis significance testing framework. For example when the $p$ p -value is small enough or the CIs of the mean effects of a studied drug and a placebo are not overlapping, scientists tend to claim significant differences while often disregarding the magnitudes and absolute differences in the effect sizes. This type of reasoning has been shown to be potentially harmful to science. Techniques relying on the visual estimation of the strength of evidence have been recom…
Tietue 2011/3
2011
Continuous experimentation on artificial intelligence software : a research agenda
2020
Moving from experiments to industrial level AI software development requires a shift from understanding AI/ ML model attributes as a standalone experiment to know-how integrating and operating AI models in a large-scale software system. It is a growing demand for adopting state-of-the-art software engineering paradigms into AI development, so that the development efforts can be aligned with business strategies in a lean and fast-paced manner. We describe AI development as an “unknown unknown” problem where both business needs and AI models evolve over time. We describe a holistic view of an iterative, continuous approach to develop industrial AI software basing on business goals, requiremen…
Hullun hauska maailma. Näkökulmia hulluutta ja poikkeavuuksia käsittelevään huumoriin opiskelijoiden digitaalisessa folkloressa
2020
Artikkelissa tarkastellaan Suomalaisen Kirjallisuuden Seuran tutkija Ulla Lipposen (1941–2015) tallettaman digitaalisen folkloreaineiston kuvaa 2000- luvun hulluudesta osana kansanhuumoria. Artikkelissa pohditaan, millaista kuvaa yhteiskunnasta ja hulluna pidetyn ilmentymistä nuorten aikuisten tallettamat esimerkit rakentavat. Mille niissä nauretaan tai millaiseen kulttuuriseen keskusteluun ne ottavat osaa huumorin keinoin? Artikkeli nostaa esille kaksi erilaista tulokulmaa hulluuteen: lääketieteelliseen diagnosointiin liittyvät näkökulmat sekä kulttuuriseen, pääosin normeja rikkovan käytöksen tuottamaan hulluuteen. Artikkeli osoittaa, että huumorin keinoin on mahdollista käsitellä arkoja y…
PARTIAL SEQUENCING OF THE BETA-GLUCOSIDASE-ENCODING GENE FROM YEAST STRAINS ISOLATED FROM MUSTS AND WINES
2008
The aim of the present work was the identification of the gene encoding for β-glucosidase and its partial sequencing in the strainsPichia anomala AL112,Hanseniaspora uvarum Y8 andSaccharomyces cerevisiae AL41. To this aim degenerated primers, designed on the basis of aminoacid similarities of four known yeast β-glucosidases, have been used in PCR amplifications. An expected fragment of about 200 bp was amplified from all the DNAs, cloned and sequenced. Sequence homology demonstrated for the first time the presence of a β-glucosidase encoding gene inHanseniaspora uvarum andSaccharomyces cerevisiae.