Search results for "N compounds"

showing 10 items of 203 documents

An in vitro comparative assessment with a series of new triphenyltin(IV) 2-/4-[(E)-2-(aryl)-1-diazenyl]benzoates endowed with anticancer activities: …

2012

Four new triphenyltin(IV) complexes of composition Ph 3SnLH (where LH = 2-/4-[(E)-2-(aryl)-1-diazenyl]benzoate) (1-4) were synthesized and characterized by spectroscopic ( 1H, 13C and 119Sn NMR, IR, 119Sn Mössbauer) techniques in combination with elemental analysis. The 119Sn NMR spectroscopic data indicate a tetrahedral coordination geometry in non-coordinating solvents. The crystal structures of three complexes, Ph 3SnL 1H (1), Ph 3SnL 3H (3), Ph 3SnL 4H (4), were determined. All display an essentially tetrahedral geometry with angles ranging from 93.50(8) to 124.5(2)°; 119Sn Mössbauer spectral data support this assignment. The cytotoxicity studies were performed with complexes 1-4, along…

Models MolecularTriphenyltin(IV) benzoatesCell SurvivalStereochemistryMolecular ConformationQuantitative Structure-Activity RelationshipAntineoplastic AgentsStereoisomerismCrystal structureCrystallography X-RayBenzoatesBiochemistryInorganic ChemistryAnti-cancer drugInhibitory Concentration 50chemistry.chemical_compoundCell Line TumorOrganotin CompoundsHumansCytotoxicityCoordination geometryQSARHydrogen bondArylTetrahedral molecular geometryHydrogen BondingStereoisomerismBenzoateschemistrySettore CHIM/03 - Chimica Generale E InorganicaCell lineTriphenyltin(IV) 2-/4-[(E)-2-(aryl)-1-diazenyl]benzoateJournal of Inorganic Biochemistry
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Insertion reaction of carbon dioxide into Sn-OR bond. Synthesis, structure and DFT calculations of di- and tetranuclear isopropylcarbonato tin(IV) co…

2006

The reaction of carbon dioxide with the stannane nBu2Sn(OiPr)2 and distannoxane [nBu2(iPrO)Sn]2O leads to the selective insertion into one Sn-OiPr bond generating the corresponding nBu2Sn(OiPr)(OCO2(i)Pr) and nBu2(iPrO)SnOSn(OCO2(i)Pr)nBu2 species. Both compounds are characterised by multinuclear NMR, FT-IR and single-crystal X-ray crystallography. In the solid state, they adopt a dimeric arrangement with bridging isopropoxy and terminal isopropylcarbonato ligands. The X-ray crystal structure of the dinuclear stannane shows that the Sn2O2 ring and the two Sn-OCO2C fragments are nearby coplanar. The same holds for the ladder-type tetranuclear distannoxane. The dimeric structures are also evi…

Models Molecularcrystal structureMagnetic Resonance SpectroscopySolid-statechemistry.chemical_elementCrystal structure[CHIM.INOR]Chemical Sciences/Inorganic chemistryCrystallography X-Ray010402 general chemistryPhotochemistrySensitivity and Specificity01 natural sciencesStannanedinuclear tetranuclear complexInorganic Chemistrychemistry.chemical_compoundisopropoxy stannaneInsertion reactiontinOrganotin CompoundsComputingMilieux_MISCELLANEOUSMolecular Structure010405 organic chemistryChemistrycarbon dioxideStereoisomerism[ CHIM.INOR ] Chemical Sciences/Inorganic chemistry0104 chemical sciencesCrystallographyModels ChemicalCarbon dioxideDFT optimized geometryTin
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Effect of tin and lead chlorotriphenyl analogues on selected living cells.

2010

Three kinds of living cells, human embryonic kidney cells, Saccharomyces cerevisiae, and Escherichia coli, were tested for their sensitivity to chlorotriphenyltin and chlorotriphenyllead. The tin compound proved definitely more toxic than the lead derivative, particularly in the case of the human embryonic kidney cells devoid of any protective cell wall. Electron paramagnetic resonance (EPR) comparative studies carried out by using a natural model liposome system (egg yolk lecithin) confirmed considerable changes within the lipid bilayer upon doping by the aforementioned additives, which may be crucial to the mechanism of the observed cell cleavage. The individual dopants revealed diverse i…

Models Molecularfood.ingredientCell SurvivalHealth Toxicology and MutagenesisCellMolecular Conformationchemistry.chemical_elementSaccharomyces cerevisiaeToxicologyCleavage (embryo)BiochemistryLecithinCell wallfoodLecithinsmedicineEscherichia coliOrganometallic CompoundsOrganotin CompoundsHumansChlorotriphenyltinLipid bilayerMolecular BiologyLiposomeElectron Spin Resonance SpectroscopyGeneral MedicineYeastChlorotriphenylleadElectron Paramagnetic Resonancemedicine.anatomical_structureMembraneHEK293 CellsBiochemistrychemistryLeadHuman Embryonic Kidney CellsLiposomesMolecular MedicineTinJournal of biochemical and molecular toxicology
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Hierarchical Assembly of TiO2 Nanoparticles on WS2 Nanotubes Achieved Through Multifunctional Polymeric Ligands

2007

Thefunctionalization of nanotubes is required in order to bene-fit from their outstanding properties, as any application inmaterials and devices is hindered by processing and manipu-lation difficulties. Only the attachment of appropriate chem-ical functionalities on the nanotube surface allows tailoringof the properties for the respective applications. As an ex-ample, the enhancement of the nanotube solubility is onemajor task since most pristine nanotubes are insoluble inboth water and organic solvents. Thus, the improvement ofthe solubility by chemical functionalization is an importantconcept for synthetic chemists and materials scientists. Tai-loring of the surface chemical bonds might a…

NanotubeMaterials scienceMacromolecular SubstancesPolymersSurface PropertiesMolecular ConformationSelective chemistry of single-walled nanotubesNanoparticleNanotechnologyLigandsBiomaterialsMaterials TestingNanotechnologyGeneral Materials ScienceParticle SizeSolubilityTitaniumchemistry.chemical_classificationSulfur CompoundsBiomoleculeGeneral ChemistryPolymerTungsten CompoundsNanostructureschemistryNanoelectronicsSurface modificationCrystallizationBiotechnologySmall
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Drug delivery devices based on mesoporous silicate.

2004

A mesoporous material based on aluminosilicate mixture was studied to investigate its ability to include drugs and then release them. Nonsteroidal anti-inflammatory agents such as diflunisal, naproxen, ibuprofen and its sodium salt have been used in this study. The preparation of the mesoporous material and its characterization by X-ray, N2 absorption-desorption isotherm, and thermogravimetry analysis have been described. Drug loading was performed by a soaking procedure. Drug-loaded matrices were characterized for entrapped drug amount, water absorption ability, and thermogravimetric behavior. Drug release studies also were performed at pH 1.1 and 6.8 mimicking gastrointestinal fluids. Exp…

NaproxenAbsorption of waterMaterials scienceNitrogenPharmaceutical ScienceDiflunisalIbuprofenmesoporous materialsDrug Delivery SystemsNaproxenDrug StabilityMaterials TestingmedicineOrganosilicon CompoundsChromatographyX-RaysWaterGeneral MedicineIbuprofenDiflunisalThermogravimetryChemical engineeringSolubilityDrug deliveryThermogravimetryAluminum SilicatesAdsorptionMesoporous materialPorositymedicine.drugMesoporous silicateAluminumDrug delivery
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Restricting Magnetic Interaction Pathways in Polyoxometalate Salts of Cationic Nitronyl Nitroxide Free Radicals

2004

Abstract : Salts 1 and 2 that combine the [W 6 O 19 ] 2- Lindqvist anion with the cationic nitronyl nitroxide (NN) free radicals p -MepyNN + and n Bu 3 NCH 2 NN + , respectively, have been synthesized and their structural and magnetic properties have been studied. Keywords: Nitroxide radicals, polyoxometalates, magnetism. Introduction Ferromagnetism based on purely organic materials has raised a lot of interest during the last decade [1]. Most of the studies have been performed with nitronyl nitroxide (NN) radicals due to their persistence, stability and ease of functionalization [2]. Bulk ferromagnetism in these compounds arises from ferromagnetic interactions between open-shell molecules …

Nitroxide mediated radical polymerizationFree RadicalsMagnetismPharmaceutical ScienceCrystallography X-RayPhotochemistryCrystal engineeringArticleNitroxide radicalsAnalytical Chemistrylcsh:QD241-441Magneticslcsh:Organic chemistryCationsDrug DiscoveryAntiferromagnetismMoleculepolyoxometalatesPhysical and Theoretical Chemistrymagnetism.ChemistryOrganic ChemistryIntermolecular forceTemperatureTungsten CompoundsCrystallographyFerromagnetismChemistry (miscellaneous)PolyoxometalateMolecular MedicineNitrogen OxidesDimerizationMolecules
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Impact of Electrical Stress and Neutron Irradiation on Reliability of Silicon Carbide Power MOSFET

2020

International audience; The combined effects of electrical stress and neutron irradiation of the last generation of commercial discrete silicon carbide power MOSFETs are studied. The single-event burnout (SEB) sensitivity during neutron irradiation is analyzed for unstressed and electrically stressed devices. For surviving devices, a comprehensive study of the breakdown voltage degradation is performed by coupling the electrical stress and irradiation effects. In addition, mutual influences between electrical stress and radiative constraints are investigated through TCAD modeling.

Nuclear and High Energy PhysicsMaterials scienceRadiation effectsSilicon carbide[PHYS.NEXP]Physics [physics]/Nuclear Experiment [nucl-ex]Stress01 natural sciencesNeutron effectsSilicon carbide (SiC)Stress (mechanics)Semiconductor device modelschemistry.chemical_compoundMOSFETReliability (semiconductor)0103 physical sciencesMOSFETSilicon carbideBreakdown voltageSemiconductor device breakdownSilicon compoundsSingle Event BurnoutNeutronIrradiationElectrical and Electronic EngineeringPower MOSFETPower MOSFETComputingMilieux_MISCELLANEOUSElectric breakdownNeutrons[PHYS]Physics [physics]010308 nuclear & particles physicsbusiness.industryLogic gatesWide band gap semiconductorsSemiconductor device reliability[SPI.TRON]Engineering Sciences [physics]/ElectronicsNuclear Energy and Engineeringchemistry13. Climate actionSingle-event burnout (SEB)Atmospheric neutronsOptoelectronicsbusinessTechnology CAD (electronics)
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Deep MRD profiling defines outcome and unveils different modes of treatment resistance in standard- and high-risk myeloma

2021

PETHEMA/GEM Cooperative Group.

OncologyAdultBoron CompoundsMalemedicine.medical_specialtyNeoplasm ResidualPhysics::Instrumentation and DetectorsClinical Trials and ObservationsImmunologyPatient subgroupsGlycineDrug resistanceBiochemistryDexamethasoneBortezomibhemic and lymphatic diseasesInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineNeoplasmHumansProgression-free survivalTreatment resistanceLenalidomideComplete responseMultiple myelomaAgedChromosome AberrationsLymphoid Neoplasiabusiness.industryCell BiologyHematologyMiddle Agedmedicine.diseaseFlow CytometryProgression-Free Survivalbody regionsClinical trialTreatment OutcomeDrug Resistance NeoplasmFemalebusinessMultiple Myeloma
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Excited-state absorption in erbium-doped silica fiber with simultaneous excitation at 977 and 1531 nm

2009

We report a study of the excited-state absorption (ESA) in erbium-doped silica fiber (EDF) pumped at 977 nm, when the fiber is simultaneously excited by signal radiation at 1531 nm. We show, both experimentally and theoretically, that ESA efficiency at 977 nm gets strongly enhanced only in the presence of signal power. Experimentally, this conclusion is supported through the detection of upconversion emission, a “fingerprint” of the ESA process, and through the measurements of the EDF nonlinear transmission coefficient for the pump wavelength, which is sensitive to the ESA value. It is shown that the experimental data are precisely modeled with an advanced five-level Er3+ model developed fo…

Optical pumpingMaterials scienceSilica fiberbusiness.industryExcited statesUNESCO::FÍSICAGeneral Physics and Astronomychemistry.chemical_elementPhoton upconversionOptical pumpingErbiumOpticschemistry:FÍSICA [UNESCO]Fiber laserExcited stateDopingSilicon compoundsOptoelectronicsDoping ; Erbium ; Excited states ; Fibre lasers ; Optical pumping ; Silicon compoundsFiberAbsorption (electromagnetic radiation)businessErbiumFibre lasersJournal of Applied Physics
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Oxygen permeability of hydrogel contact lenses with organosilicon moieties

2002

Oxygen transport through two extended wear (day and night) hydrogel contact lenses that contain organosilicon moieties (balafilcon A and lotrafilcon A) was studied in the hydrate (hydrogel) and dry (xerogel) states. The water uptake increased the oxygen permeability [(Dk)app] and transmissibility [Dk/L(av)] coefficients of the dry materials by about 70%. The (Dk)app for the hydrated lenses was determined following the so-called stack procedure. The values obtained were 107 +/- 4 barrer for balafilcon A and 141 +/- 5 barrer for lotrafilcon A, about 5-10 times larger than those previously reported for conventional (without organosilicon moieties) extended wear hydrogels contact lenses. The Dk…

Optics and PhotonicsMaterials scienceBiophysicsAnalytical chemistrychemistry.chemical_elementBioengineeringOxygenHydrogel Polyethylene Glycol DimethacrylatePermeabilityBiomaterialschemistry.chemical_compoundOxygen permeabilityMaterials TestingPolymer chemistryOrganosilicon CompoundsOrganosiliconOxygen transportWaterContact Lenses HydrophilicOxygenchemistryMechanics of MaterialsPermeability (electromagnetism)Self-healing hydrogelsCeramics and CompositesBarrerHydrateBiomaterials
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