Search results for "NEMS"

showing 10 items of 36 documents

Fabrication and Characterization of Double- and Single-Clamped CuO Nanowire Based Nanoelectromechanical Switches

2021

Electrostatically actuated nanoelectromechanical (NEM) switches hold promise for operation with sharply defined ON/OFF states, high ON/OFF current ratio, low OFF state power consumption, and a compact design. The present challenge for the development of nanoelectromechanical system (NEMS) technology is fabrication of single nanowire based NEM switches. In this work, we demonstrate the first application of CuO nanowires as NEM switch active elements. We develop bottom-up and top-down approaches for NEM switch fabrication, such as CuO nanowire synthesis, lithography, etching, dielectrophoretic alignment of nanowires on electrodes, and nanomanipulations for building devices that are suitable f…

Materials scienceFabricationGeneral Chemical EngineeringNanowire02 engineering and technology010402 general chemistry01 natural sciencesArticlebottom-uplcsh:Chemistrynanoelectromechanical switchNEMSEtching (microfabrication)Hardware_INTEGRATEDCIRCUITSGeneral Materials ScienceLithographyNanoelectromechanical systemsHardware_MEMORYSTRUCTURESbusiness.industry021001 nanoscience & nanotechnology0104 chemical sciencesCharacterization (materials science)CuOlcsh:QD1-999nanowiresPower consumptionElectrodeOptoelectronics0210 nano-technologybusinessNanomaterials
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Resonance assisted jump-in voltage reduction for electrostatically actuated nanobeam-based gateless NEM switches.

2019

Electrostatically actuated nanobeam-based electromechanical switches have shown promise for versatile novel applications, such as low power devices. However, their widespread use is restricted due to poor reliability resulting from high jump-in voltages. This article reports a new method for lowering the jump-in voltage by inducing mechanical oscillations in the active element during the switching ON process, reducing the jump-in voltage by more than three times. Ge0.91Sn0.09 alloy and Bi2Se3 nanowire-based nanoelectromechanical switches were constructed in situ to demonstrate the operation principles and advantages of the proposed method.

Materials scienceNanowireBioengineering02 engineering and technology010402 general chemistry01 natural sciencesResonanceNEMSReliability (semiconductor)General Materials SciencePower semiconductor deviceElectrical and Electronic EngineeringNanoelectromechanical systemsVoltage reductionbusiness.industryMechanical EngineeringResonanceBi2Se3General ChemistrySwitch021001 nanoscience & nanotechnology0104 chemical sciencesNanowireGeSnMechanics of MaterialsOptoelectronics0210 nano-technologyDriven elementbusinessVoltageNanotechnology
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Sequence type 101 (ST101) as the predominant carbapenem-non-susceptible Klebsiella pneumoniae clone in an acute general hospital in Italy.

2012

Klebsiella pneumoniae is one of the most common multidrug-resistant (MDR) Gram-negative organisms worldwide, responsible for high morbidity and mortality both in hospitals and alternative healthcare settings. Recently, increasing use of carbapenems has promoted the emergence and dissemination of carbapenem-non-susceptible MDR K. pneumoniae strains. All of the CNSKP strains isolated between January 2009 and December 2011 in the General Hospital of Prato (Prato, Italy) were studied. Our findings indicate that, unlike previously reported by other authors from different regions of Italy, K. pneumoniae producing KPC-2 and belonging to ST101 have been established in the area of Prato, Tuscany, It…

Microbiology (medical)CarbapenemSettore MED/07 - Microbiologia E Microbiologia ClinicaKlebsiella pneumoniaeClone (cell biology)Drug resistanceMicrobial Sensitivity TestsSettore MED/42 - Igiene Generale E ApplicataHospitals Generalbeta-LactamsMicrobiologyDrug Resistance BacterialmedicineHumansPharmacology (medical)General hospitalhospitalSequence (medicine)Cross InfectionbiologyGeneral Medicinebiology.organism_classificationST101Anti-Bacterial AgentsKlebsiella InfectionsImipenemKlebsiella pneumoniaeInfectious DiseasesCarbapenemsItalymedicine.drugInternational journal of antimicrobial agents
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Is the monoclonal spread of the ST258, KPC-3-producing clone being replaced in southern Italy by the dissemination of multiple clones of carbapenem-n…

2015

D. M. Geraci, C. Bonura, M. Giuffre, L. Saporito, G. Graziano, A. Aleo, T. Fasciana, F. Di Bernardo, T. Stampone, D. M. Palma and C. Mammina 1) Department of Sciences for Health Promotion and Mother-Child Care ‘G. D’Alessandro’, University of Palermo, 2) Postgraduate Specialty School in Hygiene and Preventive Medicine, University of Palermo, 3) Laboratory of Microbiology, General Hospital ARNAS ‘Civico, Di Cristina & Benfratelli’, 4) Laboratory of Microbiology, General Hospital Azienda Ospedaliera ‘Villa Sofia-V, Cervello’ and 5) II Intensive Care Unit, General Hospital ARNAS ‘Civico, Di Cristina & Benfratelli’, Palermo, Italy

Microbiology (medical)CarbapenemSettore MED/07 - Microbiologia E Microbiologia ClinicaKlebsiella pneumoniaeKPC Klebsiella pneumoniae epidemiology multidrug resistanceSettore MED/42 - Igiene Generale E Applicatabeta-Lactam Resistancebeta-LactamasesMicrobiologySettore MED/38 - Pediatria Generale E SpecialisticaBacterial ProteinsMedicineHumansGeneral hospitalbiologybusiness.industryGeneral Medicinebiology.organism_classificationKlebsiella InfectionsKlebsiella pneumoniaeInfectious DiseasesCarbapenemsItalybusinessHumanitiesmedicine.drugClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
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Multiclonal emergence of carbapenem-resistant Klebsiella pneumoniae in Tuscany, Italy

2010

Microbiology (medical)Settore MED/07 - Microbiologia E Microbiologia ClinicaImipenemGenotypemedicine.drug_classCarbapenem resistant Klebsiella pneumoniaemedicine.medical_treatmentAntibioticsMicrobial Sensitivity TestsBiologySettore MED/42 - Igiene Generale E ApplicataMeropenembeta-Lactam Resistancebeta-LactamasesMicrobiologychemistry.chemical_compoundmedicineHumansPharmacology (medical)Molecular EpidemiologyKlebsiella pneumoniae resistenza ai carbapenemi multiclonaleGeneral MedicineDNA FingerprintingAnti-Bacterial AgentsBacterial Typing TechniquesElectrophoresis Gel Pulsed-FieldKlebsiella InfectionsMultiple drug resistanceKlebsiella pneumoniaePhenotypeInfectious DiseasesCarbapenemsItalychemistryBeta-lactamaseErtapenemmedicine.drugBeta lactam antibioticsInternational Journal of Antimicrobial Agents
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Targeting the Class A Carbapenemase GES-5 via Virtual Screening

2020

The worldwide spread of &beta

Models MolecularDrugantibiotic resistanceGES-5Antibiotic resistancemedia_common.quotation_subjectIn silicoDrug Evaluation Preclinicallcsh:QR1-502Guyana extended-spectrum-β-lactamaseMicrobial Sensitivity TestsComputational biologyBiologyBiochemistrybeta-LactamasesArticlelcsh:Microbiologyguyana extended-spectrum-β-lactamasecarbapenemase03 medical and health sciencesAntibiotic resistanceBacterial ProteinsDrug Resistance BacterialHumansAntibiotic resistance; GES-5; Guyana extended-spectrum-β-lactamase; carbapenemase; virtual screening; docking; noncovalent inhibitionges-5noncovalent inhibitionMolecular Biology030304 developmental biologymedia_common0303 health sciencesVirtual screening030306 microbiologyAntibiotic resistance; Carbapenemase; Docking; GES-5; Guyana extended-spectrum-β-lactamase; Noncovalent inhibition; Virtual screeningHit to leadvirtual screeningAntimicrobialAnti-Bacterial AgentsCarbapenemsdockingBiomolecules
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Modello numerico per la caratterizzazione elettromeccanica dei nanotubi di carbonio

2016

Nell’ultimo decennio i nanotubi di carbonio (Carbon nanotubes, CNTs) hanno suscitato un considerevole interesse nella comunità scientifica internazionale a causa delle loro proprietà meccaniche, bassa densità ed elevata conducibilità termica. I CNT possiedono inoltre peculiari proprietà elettroniche dipendenti da elicoicità e stato di deformazione, rendendoli potenziali elementi costruttivi di una nuova tecnologia nano-elettronica. Numerosissimi dispositivi elettronici basati sui CNTs (transistors, nano-switches, attuatori, ecc.) sono già stati realizzati. Un nuovo approccio è stato sviluppato per investigare la deformazione dei CNTs e si basa su modelli agli elementi finiti accuratamente s…

Nanotubi di carbonio Comportamento elettromeccanico Metodi Numerici NEMS.Settore ING-IND/14 - Progettazione Meccanica E Costruzione Di Macchine
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Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure : the DIANA study

2020

© 2020 The Author(s).

OriginalDELPHI METHODCritical Care and Intensive Care MedicineGUIDELINESlaw.invention0302 clinical medicineAnti-Infective Agents[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseaseslawEpidemiologyMedicine and Health SciencesAntimicrobial de-escalationEPIDEMIOLOGYComputingMilieux_MISCELLANEOUS[SDV.MHEP.ME]Life Sciences [q-bio]/Human health and pathology/Emerging diseasesVentilator-associated pneumoniaIntensive care unitAnti-Bacterial Agents3. Good healthIntensive Care UnitsSTEWARDSHIP PROGRAM[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/VirologyCohortAntimicrobial de-escalation; Bacterial infection; Clinical cure; Empirical therapy; Intensive care unit;Clinical cureAntimicrobial de-escalation; Bacterial infection; Clinical cure; Empirical therapy; Intensive care unitAdultmedicine.medical_specialtyCombination therapyCritical IllnessANTIBIOTIC-THERAPYNO03 medical and health sciences[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemBETA-LACTAMInternal medicineSettore MED/41 - ANESTESIOLOGIAmedicineHumans[SDV.MP.PAR]Life Sciences [q-bio]/Microbiology and Parasitology/ParasitologyIntensive care unitVENTILATOR-ASSOCIATED PNEUMONIAbusiness.industrySEPTIC SHOCKR-PACKAGEbacterial infectionIntensive care unit.030208 emergency & critical care medicinemedicine.disease[SDV.MP.BAC]Life Sciences [q-bio]/Microbiology and Parasitology/BacteriologyEmpirical therapyDiscontinuationSEVERE SEPSISlnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4]Carbapenems030228 respiratory systemRelative riskBacterial infectionbusinessDe-escalation
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Human Amnion-Derived Mesenchymal Stromal Cells: A New Potential Treatment for Carbapenem-Resistant Enterobacterales in Decompensated Cirrhosis

2022

Background: Spontaneous bacterial peritonitis (SBP) is a severe and often fatal infection in patients with decompensated cirrhosis and ascites. The only cure for SBP is antibiotic therapy, but the emerging problem of bacterial resistance requires novel therapeutic strategies. Human amniotic mesenchymal stromal cells (hA-MSCs) possess immunomodulatory and anti-inflammatory properties that can be harnessed as a therapy in such a context. Methods: An in vitro applications of hA-MSCs in ascitic fluid (AF) of cirrhotic patients, subsequently infected with carbapenem-resistant Enterobacterales, was performed. We evaluated the effects of hA-MSCs on bacterial load, innate immunity factors, and macr…

QH301-705.5Placentacirrhosis; ascitic fluid; spontaneous bacterial peritonitis; human amnion-derived mesenchymal stromal cells; carbapenem-resistant Enterobacterales; pattern recognition molecules; ficolins; complement; placentaComplementEnterobacterPeritonitisMesenchymal Stem Cell Transplantationbeta-Lactam ResistanceCatalysisImmunomodulationInorganic ChemistryPhagocytosisSpontaneous bacterial peritonitisHumansHuman amnion-derived mesenchymal stromal cellsAmnionBiology (General)Physical and Theoretical ChemistryQD1-999Complement ActivationMolecular BiologySpectroscopyAscitic fluidMacrophagesCarbapenem-resistant EnterobacteralesOrganic ChemistryPattern recognition moleculesEnterobacteriaceae InfectionsMesenchymal Stem CellsPeritoneal FibrosisFicolinsComplement System ProteinsGeneral MedicineBacterial LoadComputer Science ApplicationsChemistryTreatment OutcomeCirrhosisCarbapenemsReceptors Pattern RecognitionDisease SusceptibilityInflammation MediatorsBiomarkersInternational Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 857
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Analytical Solutions of Viscoelastic Nonlocal Timoshenko Beams

2022

A consistent nonlocal viscoelastic beam model is proposed in this paper. Specifically, a Timoshenko bending problem, where size- and time-dependent effects cannot be neglected, is investigated. In order to inspect scale phenomena, a stress-driven nonlocal formulation is used, whereas to simulate time-dependent effects, fractional linear viscoelasticity is considered. These two approaches are adopted to develop a new Timoshenko bending model. Analytical solutions and application samples of the proposed formulation are presented. Moreover, in order to show influences of viscoelastic and size effects on mechanical response, parametric analyses are provided. The contributed results can be usefu…

Small-scale beamGeneral Mathematicsfractional calculusFractional calculuMEMS/NEMS; fractional calculus; stress-driven nonlocality; small-scale beams; size effectsstress-driven nonlocalitysize effectsMEMS/NEMSQA1-939Computer Science (miscellaneous)Size effectSettore ICAR/08 - Scienza Delle Costruzionismall-scale beamsEngineering (miscellaneous)MathematicsMathematics
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