Search results for "Neste"

Data from: Constant, cycling, hot and cold thermal environments: strong effects on mean viability but not on genetic estimates

2012

It has frequently been suggested that trait heritabilities are environmentally sensitive, and there are genetic trade-offs between tolerating different environments such as hot and cold or constant and fluctuating temperatures. Future climate predictions suggest an increase in both temperatures and their fluctuations. How species will respond to these changes is uncertain, particularly as there is a lack of studies which compare genetic performances in constant vs. fluctuating environments. In this study, we used a nested full-sib/half-sib breeding design to examine how the genetic variances and heritabilities of egg-to-adult viability differ at high and low temperatures with and without da…

THE EFFECTS OF MUSCARINIC AGONISTS AND ANTAGONISTS ON ACETYLCHOLINE RELEASE FROM PERIPHERAL CHOLINERGIC NERVES IN THE ABSENCE AND PRESENCE OF A CHOLI…

1980

A High Sensitive Nested PCR for Toxoplasma gondii Detection in Animal and Food Samples

2013

Toxoplasma gondii is a major food and waterborne transmitted parasite world-wide. The tissues and meat samples of many warm blooded animals can contain tissues cysts from chronic toxoplasmosis. Water and vegetable can be contaminated by the parasitic oocysts shed through the feces of infected cats, representing the definitive host of the parasite. A sensitive PCR for Toxoplasma gondii detection is described. The first step amplified the region between the 28S and 18S rDNA in the closely related T. gondii and Neospora caninum; RFLP analysis distinguished the DNA from the two morphologically identical parasites. Although N. caninum is not involved in human transmission, so far, it is importan…

Uptake of Acetylcholine by Bean Hypocotyl Hooks

1978

Summary The uptake of acetylcholine by etiolated hypocotyl hooks of beans ( Phaseolus vulgaris L.) is influenced by light and the pH-value of the incubation medium. Acetylcholine is hydrolysed up to 90 % during the uptake. The hydrolysis is inhibited by pH-value lower than 6.0 and by eserine, an inhibitor of the acetylcholinesterase. The high amount of hydrolysis is a serious problem in experiments involving acetylcholine and necessitates the inclusions of adequate controls without which direct effects of acetylcholine cannot be distinguished from reactions of its metabolic products.

Elimination of Parathion by Hemoperfusion in Severe E 605 ForteR Intoxication in Vivo

1978

Severe parathion (P) intoxication results in complete inhibition of cholinesterase activity and toxic accumulation of acetylcholine. Besides these well known biochemical changes, there is evidence of direct toxic effects on the cardio-vascular system which may prove fatal due to an excess of P.

A perioperative uncontrollable bleeding in an elderly patient with acquired hemophilia A: a case report

2013

Key Clinical Message Acquired hemophilia A should be taken into account in the differential diagnosis of perioperative bleeding in patients without any apparent reason for activated partial thromboplastin time prolongation.

Steppes of Southern Siberia - Experiences from the 6th EDGG Research Expedition to Khakassia, Russia (22 July – 1 August 2013)

2013

The 6th EDGG Research Expedition took place in summer 2013 in the Kuznetsky Alatau Mountains, part of the Altai-Sayanian mountain region (Republic of Khakassia, Russia). A group of 14 scientists from seven countries studied the variety of steppe vegetation in two regions of the "Khakassky" Reserve – Lake Itkul (Shira region) and Podzaploty (Ordzhenikidzevsky region). Standardised sampling procedures including nested-plot series and phytosociological relevés of 10-m2 plots were used to sample steppes of European-Siberian (Festuco-Brometea) and Central Asian (Cleistogenetea squarrosae) types. All terricolous plants present in the plots were sampled, including perennial and annual vascular pla…

Experimental and Emerging Free Fatty Acid Receptor Agonists for the Treatment of Type 2 Diabetes

2022

The current management of Type 2 Diabetes Mellitus (T2DM) includes incretin-based treatments able to enhance insulin secretion and peripheral insulin sensitivity as well as improve body mass, inflammation, plasma lipids, blood pressure, and cardiovascular outcomes. Dietary Free Fatty Acids (FFA) regulate metabolic and anti-inflammatory processes through their action on incretins. Selective synthetic ligands for FFA1-4 receptors have been developed as potential treatments for T2DM. To comprehensively review the available evidence for the potential role of FFA receptor agonists in the treatment of T2DM, we performed an electronic database search assessing the association between FFAs, T2DM, i…

Method for evaluating the bioconversion of radioactive polyunsaturated fatty acids by use of reversed-phase liquid chromatography

1988

Abstract Reversed-phase high-performance liquid chromatography on a thermostatted octadecylsilyl column was used to separate mixtures of labelled polyunsaturated fatty acids (as their methyl esters) formed by successive desaturations and elongations of labelled linoleic (18:2 n - 6) or linolenic (18:3 n -3) acid by rat liver microsomes. Acetonitrile-water mixtures were used for elution of the esters. Unsaturated and saturated esters were detected by their refractive indices. The order of elution of fatty acid methyl esters in complex mixtures varies as a function of the chain length and unsaturation, analysis temperature, water concentration and solvent flow-rate. The peak areas vary as a f…

Chapter 17: The cholinesterases: a discussion of some unanswered questions

1993

Publisher Summary During the past three decades, a vast body of specificity and kinetic data relating to the cholinesterases has accumulated, which must now be explained by the extremely interesting new sequence and X-ray crystallographic results presented by MassouliC et al. As this chapter shows, the cholinesterases are remarkable among enzymes in having a broad specificity embracing both charged and uncharged substrates but with a clearly expressed preference, at any rate in the aliphatic series, for the acylcholine configuration: a classical example of the principle of complementariness between substrate and active site as the basis for enzyme action. It is well known that AChE exists i…