Search results for "Oates"

showing 10 items of 145 documents

Colorado potato beetle chymotrypsin genes are differentially regulated in larval midgut in response to the plant defense inducer hexanoic acid or the…

2019

When Colorado potato beetle larvae ingested potato plants treated with the plant defense inducer compound hexanoic acid, midgut chymotrypsin enzyme activity increased, and the corresponding chymotrypsin genes were differentially expressed, evidence of the larval digestive proteolytic system's plasticity. We previously reported increased susceptibility to Cry3Aa toxin in larvae fed hexanoic acid treated plants. Here we show that the most expressed chymotrypsin gene in larvae fed hexanoic acid treated plants, CTR6, was dramatically downregulated in Cry3Aa intoxicated larvae. lde-miR-965-5p and lde-miR-9a-5p microRNAs, predicted to target CTR6, might be involved in regulating the response to h…

0106 biological sciences0301 basic medicineGenes Insectmedicine.disease_cause01 natural sciencesMicrobiologyHemolysin Proteins03 medical and health scienceschemistry.chemical_compoundBacterial ProteinsBacillus thuringiensisPlant defense against herbivorymedicineAnimalsChymotrypsinCaproatesEcology Evolution Behavior and SystematicsSolanum tuberosumHexanoic acidChymotrypsinBacillus thuringiensis ToxinsbiologyToxinfungiColorado potato beetlefood and beveragesMidgutbiology.organism_classificationEnzyme assayColeopteraEndotoxins010602 entomology030104 developmental biologyGene Expression RegulationchemistryLarvabiology.proteinDigestive SystemJournal of Invertebrate Pathology
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Dehydration rate determines the degree of membrane damage and desiccation tolerance in bryophytes.

2016

Desiccation tolerant (DT) organisms are able to withstand an extended loss of body water and rapidly resume metabolism upon rehydration. This ability, however, is strongly dependent on a slow dehydration rate. Fast dehydration affects membrane integrity leading to intracellular solute leakage upon rehydration and thereby impairs metabolism recovery. We test the hypothesis that the increased cell membrane damage and membrane permeability observed under fast dehydration, compared with slow dehydration, is related to an increase in lipid peroxidation. Our results reject this hypothesis because following rehydration lipid peroxidation remains unaltered, a fact that could be due to the high incr…

0106 biological sciences0301 basic medicineMembrane permeabilityPhysiologyPlant ScienceBryophytamedicine.disease_cause01 natural sciencesFluorescenceLipid peroxidationCell membraneDesiccation tolerance03 medical and health scienceschemistry.chemical_compoundStress PhysiologicalBotanyGeneticsmedicineHydroxybenzoatesDehydrationDesiccationDehydrationCell MembraneWaterCell BiologyGeneral Medicinemedicine.diseaseOxygenOxidative Stress030104 developmental biologymedicine.anatomical_structurechemistryBiophysicsLipid PeroxidationDesiccationReactive Oxygen SpeciesIntracellularOxidative stressPlant Shoots010606 plant biology & botanyPhysiologia plantarum
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Oxylipin mediated stress response of a miraculin-like protease inhibitor in Hexanoic acid primed eggplant plants infested by Colorado potato beetle

2017

Insect-plant interactions are governed by a complex equilibrium between the mechanisms through which plant recognize insect attack and orchestrate downstream signaling events that trigger plant defense responses, and the mechanisms by which insects overcome plant defenses. Due to this tight and dynamic interplay, insight into the nature of the plant defense response can be gained by analyzing changes in the insect herbivores digestive system upon plant feeding. In this work we have identified a Solanum melongena miraculin-like protease inhibitor in the midgut juice of Colorado potato larvae feeding on eggplant plants treated with the natural inducer of plant defenses hexanoic acid. We analy…

0106 biological sciences0301 basic medicinePhysiologyMiraculinPlant ScienceEggplant01 natural sciences03 medical and health scienceschemistry.chemical_compoundGene Expression Regulation PlantBotanyPlant defense against herbivoryAnimalsColorado potato beetleProtease InhibitorsOxylipinsSolanum melongenaCaproatesMiraculin-like proteinHexanoic acidbiologyColorado potato beetlefungiPlant physiologyfood and beveragesOxylipinbiology.organism_classificationCell biologyColeoptera030104 developmental biologychemistryDefense primingSolanumHexanoic acidAgronomy and Crop ScienceSolanaceae010606 plant biology & botany
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Recovery of polyhydroxyalkanoates (PHAs) from wastewater : a review

2020

Abstract Polyhydroxyalkanoates (PHAs) are biopolyesters accumulated as carbon and energy storage materials under unbalanced growth conditions by various microorganisms. They are one of the most promising potential substitutes for conventional non-biodegradable plastics due to their similar physicochemical properties, but most important, its biodegradability. Production cost of PHAs is still a great barrier to extend its application at industrial scale. In order to reduce that cost, research is focusing on the use of several wastes as feedstock (such as agro-industrial and municipal organic waste and wastewater) in a platform based on mixed microbial cultures. This review provides a critical…

0106 biological sciencesEnvironmental EngineeringCircular economyScale-upMixed microbial culturesBioengineeringWastewater treatmentWastewater010501 environmental sciencesRaw material01 natural sciencesPolyhydroxyalkanoatesBiopolymers010608 biotechnologyIndustryWaste WaterWaste Management and Disposal0105 earth and related environmental sciencesResource recoverySettore ICAR/03 - Ingegneria Sanitaria-AmbientaleWaste managementRenewable Energy Sustainability and the EnvironmentPolyhydroxyalkanoatesGeneral MedicineBiodegradable wasteResource recoveryBiodegradationCarbonWastewaterSCALE-UPEnvironmental scienceSewage treatment
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Bioplastic recovery from wastewater: A new protocol for polyhydroxyalkanoates (PHA) extraction from mixed microbial cultures

2019

Abstract A new protocol for polyhydroxyalkanoates (PHA) extraction from mixed microbial cultures (MMCs) is proposed. PHA-accumulating capacity of the MMC was selected in a sequencing batch reactor (SBR) fed with a synthetic effluent emulating a fermented oil mill wastewater (OMW). The highest recovery yield and purity (74 ± 8% and 100 ± 5%, respectively) was obtained when using NH4-Laurate for which operating conditions of the extraction process such as temperature, concentration and contact time were optimized. Best conditions for PHA extraction from MMC turned to be: i) a pre-treatment with NaClO at 85 °C with 1 h of contact time, followed by ii) a treatment with lauric acid in a ratio ac…

0106 biological sciencesEnvironmental EngineeringPHABioengineeringSequencing batch reactorWastewater treatment010501 environmental sciencesWastewater01 natural sciencesBioplasticPolyhydroxyalkanoateschemistry.chemical_compoundBioreactors010608 biotechnologyBiomassWaste Management and DisposalEffluent0105 earth and related environmental sciencesSettore ICAR/03 - Ingegneria Sanitaria-AmbientaleRenewable Energy Sustainability and the EnvironmentChemistryPolyhydroxyalkanoatesExtraction (chemistry)Water resource recoveryGeneral MedicinePulp and paper industryLauric acidBioplasticWastewaterFermentationFermentationPlastics
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Does interindividual variability of saliva affect the release and metabolization of aroma compounds ex vivo? The particular case of elderly suffering…

2019

The aim of this work was to study the effects of interindividual variability of human elderly saliva on aroma release and metabolization by ex vivo approaches. Thirty individuals suffering or not from hyposalivation were selected from a panel formed by 110 elderly people (aged >65 years old) that were matched by age and sex. Then, their stimulated saliva samples were independently incubated in presence of three aroma compounds (ethyl hexanoate, octanal, 2-nonanone) to perform headspace-gas chromatography and liquid/liquid extraction-gas chromatography mass spectrometry analyses. These assays revealed that the extent of saliva effect on the release and metabolization of aroma compounds was h…

0106 biological sciencesMaleTasteSalivaChemical PhenomenaPharmaceutical SciencePhysiologyaroma release;metabolisation;saliva;hyposalivation;elderly;total antioxidant capacity01 natural sciencesAntioxidantschemistry.chemical_compoundmétabolisationComputingMilieux_MISCELLANEOUS2. Zero hungerAged 80 and overbiologyEthyl hexanoate04 agricultural and veterinary sciencesKetones040401 food science3. Good healthSmellaroma releaseAlimentation et NutritionFemaletotal antioxidant capacitycapacité antioxydanteAffect (psychology)elderlyXerostomiaGas Chromatography-Mass Spectrometrypersonne âgée0404 agricultural biotechnology010608 biotechnologyDiabetes mellitusmedicineFood and NutritionHumansSalivasalivehyposalivationCaproatesAromaAgedmetabolisationAldehydesVolatile Organic Compoundsbusiness.industrylibération d'arômemedicine.diseasebiology.organism_classificationHuman nutritionchemistryOdorantsQuality of Lifebusiness[SDV.AEN]Life Sciences [q-bio]/Food and NutritionEx vivoFood Sciencesécrétion salivaireJournal of texture studies
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Characterization of (3H) acifluorfen binding to purified pea etioplasts, and evidence that protoporphyrinogen oxidase specifically binds acifluorfen

1992

It is now generally accepted that protoporphyrinogen oxidase is the target-enzyme for diphenylether-type herbicides. Recent studies [Camadro, J-M., Matringe, M., Scalla, R. & Labbe, P. (1991) Biochem. J. 277, 17–21] have revealed that in maize, diphenyl ethers competitively inhibit protoporphyrinogen oxidase with respect to its substrate, protoporphyrinogen IX. In this study, we show that, in purified pea etioplast, [3H]acifluorfen specifically binds to a single class of high-affinity binding sites with an apparent dissociation constant of 6.2 ± 1.3 nM and a maximum density of 29 ± 5 nmol/g protein. [3H]Acifluorfen binding reaches equilibrium in about 1 min at 30°C. Half dissociation occurs…

0106 biological sciencesOxidoreductases Acting on CH-CH Group DonorsStereochemistry[SDV]Life Sciences [q-bio]PhthalimidesAcifluorfen01 natural sciencesBiochemistrySubstrate Specificity03 medical and health scienceschemistry.chemical_compoundMALHERBOLOGIEEtioplastProtoporphyrinogen OxidaseBinding siteComputingMilieux_MISCELLANEOUS030304 developmental biologychemistry.chemical_classificationOrganelles0303 health sciencesOxidase testBinding SitesPlants MedicinalProtoporphyrin IXMolecular StructureBIOCHIMIEHerbicidesFabaceaeProtoporphyrinogen IX[SDV] Life Sciences [q-bio]KineticsEnzymechemistryBiochemistryNitrobenzoatesProtoporphyrinogen oxidaseOxidoreductases010606 plant biology & botany
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Antiviral properties of silver nanoparticles against norovirus surrogates and their efficacy in coated polyhydroxyalkanoates systems

2017

Silver nanoparticles (AgNP) have strong broad-spectrum antimicrobial activity and gained increased attention for the development of AgNP based products, including medical and food applications. Initially, the efficacy of AgNP and silver nitrate (AgNO3) was evaluated for inactivating norovirus surrogates, the feline calicivirus (FCV) and the murine norovirus (MNV). These norovirus surrogates were exposed to AgNO3 and AgNP solutions for 24 h at 25 °C and then analyzed by cell-culture assays. Both AgNP and silver ions significantly decreased FCV and MNV infectivity in a dose-dependent manner between concentrations of 2.1 and 21 mg/L. Furthermore, poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (…

0301 basic medicine030106 microbiologyved/biology.organism_classification_rank.speciesNoroviruses02 engineering and technologyengineering.materialSilver nanoparticlePolyhydroxyalkanoatesMicrobiology03 medical and health scienceschemistry.chemical_compoundCoatingFiberFeline calicivirusbiologyElectrospinningved/biologyChemistryPolyhydroxyalkanoates021001 nanoscience & nanotechnologybiology.organism_classificationElectrospinningSilver nitrateengineeringActive packagingSilver nanoparticles0210 nano-technologyFood ScienceMurine norovirusNuclear chemistry
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Angiotensin II type 1 receptor antagonists in animal models of vascular, cardiac, metabolic and renal disease

2016

AbstractWe have reviewed the effects of angiotensin II type 1 receptor antagonists (ARBs) in various animal models of hypertension, atherosclerosis, cardiac function, hypertrophy and fibrosis, glucose and lipid metabolism, and renal function and morphology. Those of azilsartan and telmisartan have been included comprehensively whereas those of other ARBs have been included systematically but without intention of completeness. ARBs as a class lower blood pressure in established hypertension and prevent hypertension development in all applicable animal models except those with a markedly suppressed renin–angiotensin system; blood pressure lowering even persists for a considerable time after d…

0301 basic medicineBlood Pressure030204 cardiovascular system & hematologyKidneyurologic and male genital diseasesBenzoatesAnimals Genetically ModifiedRenin-Angiotensin SystemGene Knockout Techniques0302 clinical medicineAzilsartanPharmacology (medical)TelmisartanOxadiazolesKidneybiologyStrokemedicine.anatomical_structureCardiovascular DiseasesHypertensionDrug Therapy Combinationmedicine.drugmedicine.medical_specialty03 medical and health sciencesMetabolic DiseasesCulture TechniquesInternal medicineRenin–angiotensin systemmedicineAnimalsHumansAntihypertensive AgentsPharmacologyAngiotensin II receptor type 1business.industryAngiotensin-converting enzymeAtherosclerosisLipid Metabolismmedicine.diseaseDisease Models AnimalGlucose030104 developmental biologyBlood pressureEndocrinologyPathophysiology of hypertensionbiology.proteinBenzimidazolesEndothelium VascularTelmisartanbusinessAngiotensin II Type 1 Receptor BlockersPharmacology & Therapeutics
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Anthranilamide-based 2-phenylcyclopropane-1-carboxamides, 1,1'-biphenyl-4-carboxamides and 1,1'-biphenyl-2-carboxamides: Synthesis biological evaluat…

2017

Abstract Several anthranilamide-based 2-phenylcyclopropane-1-carboxamides 13a-f, 1,1’-biphenyl-4-carboxamides 14a-f and 1,1’-biphenyl-2-carboxamides 17a-f were obtained by a multistep procedure starting from the (1S,2S)-2-phenylcyclopropane-1-carbonyl chloride 11, the 1,1'-biphenyl-4-carbonyl chloride 12 or the 1,1'-biphenyl-2-carbonyl chloride 16 with the appropriate anthranilamide derivative 10a-f. Derivatives 13a-f, 14a-f and 17a-f showed antiproliferative activity against human leukemia K562 cells. Among these derivatives 13b, 14b and 17b exerted a particular cytotoxic effect on tumor cells. Derivative 17b showed a better antitumoral effect on K562 cells than 13b and 14b. Analyses perfo…

0301 basic medicineG2 Phase2-Phenylcyclopropane-1-carboxamides 11’-biphenyl-4-carboxamides 11’-biphenyl-2-carboxamides G2/M arrest Phospho-ATM and gH2AX increaseDNA RepairDNA repairStereochemistryAntineoplastic AgentsApoptosisChloride03 medical and health scienceschemistry.chemical_compound0302 clinical medicineSettore BIO/10 - BiochimicaDrug DiscoverymedicineCytotoxic T cellHumansortho-AminobenzoatesMode of actionCell ProliferationPharmacologyChemistryOrganic ChemistryGeneral MedicineCell Cycle CheckpointsCell cycleSettore CHIM/08 - Chimica Farmaceutica030104 developmental biologyMechanism of actionApoptosis030220 oncology & carcinogenesismedicine.symptomK562 CellsDNAmedicine.drugDNA Damage
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