Search results for "P.O.S"

showing 10 items of 5765 documents

The corticotrophin-releasing factor/urocortin system regulates white fat browning in mice through paracrine mechanisms.

2015

Objectives:\ud The corticotrophin-releasing factor (CRF)/urocortin system is expressed in the adipose tissue of mammals, but its functional role in this tissue remains unknown.\ud \ud Methods:\ud Pharmacological manipulation of the activity of CRF receptors, CRF1 and CRF2, was performed in 3T3L1 white pre-adipocytes and T37i brown pre-adipocytes during in vitro differentiation. The expression of genes of the CRF/urocortin system and of markers of white and brown adipocytes was evaluated along with mitochondrial biogenesis and cellular oxygen consumption. Metabolic evaluation of corticosterone-deficient or supplemented Crhr1-null (Crhr1−/−) mice and their wild-type controls was performed alo…

obesitycrf1Corticotropin-Releasing Hormonecrf2Endocrinology Diabetes and MetabolismIMPAIRED STRESS-RESPONSE[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionAdipocytes WhiteMedicine (miscellaneous)urocortinWhite adipose tissueMOUSEMicebrown adiposte tissue0302 clinical medicineBrowningUrocortinsUrocortin0303 health sciencesNutrition and Dietetics[SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolismParacrine mechanisms[ SDV.MHEP.EM ] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolismImmunohistochemistryADIPOCYTESAdipocytes BrownADIPOSE-TISSUESKELETAL-MUSCLEhormones hormone substitutes and hormone antagonistsSignal TransductionEXPRESSIONmedicine.medical_specialtyendocrine systemTHERMOGENESISBiologycrfReceptors Corticotropin-Releasing Hormone03 medical and health scienceswhite adipose tissueInternal medicine3T3-L1 CellsmedicineAnimalsRNA MessengerGLUCOCORTICOIDS030304 developmental biologyENERGY HOMEOSTASISCorticotrophin releasing factoradipose plasticityPigments BiologicalUROCORTIN-II GENEQPEndocrinologyGene Expression Regulation[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition030217 neurology & neurosurgery
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Effects of exercise and diet on sleep among overweight and obese men with chronic insomnia symptoms

2016

obesityexercisemalesylipainoliikuntaruokavaliotkeski-ikäisetunettomuuschronic insomnia symptomsliikuntalääketiedeoverweightsleep onsetlihavuusmiehetdietravitsemusunihäiriötfyysinen aktiivisuusnukahtaminen
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Système olfactif et neurobiologie

2006

Les connaissances neurobiologiques sur l’odorat progressent désormais rapidement depuis la découverte des récepteurs des odorants, remarquables par leur grand nombre et leur diversité. Des réponses sont maintenant apportées aux questions posées par les propriétés originales de la perception olfactive dont beaucoup sont déterminées dès le niveau de l’organe olfactif, et sont fortement déterminées par la génétique. Les connaissances génétiques sur les récepteurs dévoilent une considérable réduction du nombre de gènes olfactifs fonctionnels dans l’espèce humaine et alimentent une réflexion sur l’évolution de l’odorat. Autre avancée riche de promesses : l’application à l’olfaction des méthodes …

odoratsymbolismesense of smellparfumPhilosophy[SCCO.NEUR]Cognitive science/Neuroscience[SCCO.NEUR] Cognitive science/Neuroscienceimagerie cérébrale fonctionnelleolfactory receptorssensolfactory perceptionsanthropologieEuroperécepteur d’odorantfunctional cerebral imagerysemantiqueneurobiologieAnthropology[ SCCO.NEUR ] Cognitive science/NeuroscienceNouvelle-GuinéeMadagascarévolutionperception olfactiveHumanitiesolfaction
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Oluen hivenainepitoisuuksien analysointi

2015

Tämän Pro gradu -tutkielman kirjallisessa osassa käsiteltiin hivenaineiden tarvetta palautumisen kannalta ja alkoholin tuottamia vaikutuksia palautumiseen. Lisäksi selvitettiin orgaanista ainesta sisältävien näytteiden esikäsittelymenetelmiä ja induktiivisesti kytketyn plasma-optisen emissiospektrometrin (ICP-OES) käyttöä hivenaineiden analysoinnissa. Ultraääni, mikroaalto, tuhkistus ja muita esikäsittelymenetelmiä ja niiden eroavaisuuksia ja eroja esiteltiin, koska oluen hivenaineanalyysien onnistumiseksi on erityisen tärkeää saada hiilidioksidi poistumaan näytetaustasta ja nämä menetelmät olivat hyväksi havaittuja kyseiseen toimintaan. Oluesta löytyy kirjallisuudesta hyvin vähän tutkimuks…

olutkuntoliikuntapalautuminenICP-OEShivenaineet
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Optical properties and photosensitivity of vacuum synthesized Ge-doped sol-gel amorphous SiO/sub 2/

2005

We report optical and electron paramagnetic resonance investigations of gamma ray irradiation effects in sol-gel Ge-doped amorphous SiO/sub 2/. The studied materials have Ge-doping levels up to 10/sup 4/ molar part per million and were densified by two routes differing for the atmosphere: O/sub 2/+N/sub 2/ or vacuum. The obtained results evidence that irradiation affects matrix sites inducing paramagnetic defects. Furthermore, the comparison between the two densification procedures shows that vacuum atmosphere induces higher radiation sensitivity.

optical fiberMaterials sciencePhotoluminescenceradiation effectDopingtechnology industry and agricultureAnalytical chemistrychemistry.chemical_elementGermaniumAmorphous solidlaw.inventionParamagnetismNuclear magnetic resonancechemistrylawradiation-induced attenuationIrradiationElectron paramagnetic resonanceSol-gelProceedings of 2005 IEEE/LEOS Workshop on Fibres and Optical Passive Components, 2005.
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Structural and optical characterization of ZnS ultrathin films prepared by low-temperature ALD from diethylzinc and 1.5-pentanedithiol after various …

2019

The structural and optical evolution of the ZnS thin films prepared by atomic layer deposition (ALD) from the diethylzinc (DEZ) and 1,5-pentanedithiol (PDT) as zinc and sulfur precursors was studied. A deposited ZnS layer (of about 60 nm) is amorphous, with a significant S excess. After annealing, the stoichiometry improved for annealing temperatures &ge

optical propertiesMaterials scienceAnnealing (metallurgy)Analytical chemistryEpitaxylcsh:TechnologyArticleAnnealingAtomic layer depositionatomic layer deposition (ALD)General Materials ScienceThin filmlcsh:Microscopylcsh:QC120-168.85lcsh:QH201-278.5Optical propertieslcsh:TAtmospheric temperature rangeatomikerroskasvatusAmorphous solidAtomic layer deposition (ALD)lcsh:TA1-2040lcsh:Descriptive and experimental mechanicsannealinglcsh:Electrical engineering. Electronics. Nuclear engineeringCrystalliteohutkalvotlcsh:Engineering (General). Civil engineering (General)lcsh:TK1-9971StoichiometryZnS thin films
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Evolution of microstructure and related optical properties of ZnO grown by atomic layer deposition.

2013

A study of transmittance and photoluminescence spectra on the growth of oxygen-rich ultra-thin ZnO films prepared by atomic layer deposition is reported. The structural transition from an amorphous to a polycrystalline state is observed upon increasing the thickness. The unusual behavior of the energy gap with thickness reflected by optical properties is attributed to the improvement of the crystalline structure resulting from a decreasing concentration of point defects at the growth of grains. The spectra of UV and visible photoluminescence emissions correspond to transitions near the band-edge and defect-related transitions. Additional emissions were observed from band-tail states near th…

optical propertiesPhotoluminescenceMaterials scienceBand gapGeneral Physics and AstronomyNanotechnology02 engineering and technologylcsh:Chemical technology010402 general chemistrylcsh:Technology01 natural sciencesFull Research PaperAtomic layer depositionCondensed Matter::Materials ScienceTransmittance[CHIM]Chemical SciencesNanotechnologylcsh:TP1-1185General Materials ScienceElectrical and Electronic EngineeringThin filmlcsh:ScienceComputingMilieux_MISCELLANEOUSlcsh:Tbusiness.industry021001 nanoscience & nanotechnologyMicrostructurelcsh:QC1-9990104 chemical sciencesAmorphous solidNanosciencethin filmsatomic layer depositionZnOOptoelectronicslcsh:QphotoluminescenceCrystallite0210 nano-technologybusinesslcsh:PhysicsBeilstein journal of nanotechnology
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Sex steroid hormone receptors, their ligands, and nuclear and non-nuclear pathways

2015

The ability of a cell to respond to a particular hormone depends on the presence of specific receptors for those hormones. Once the hormone has bound to its receptor, and following structural and biochemical modifications to the receptor, it separates from cytoplasmic chaperone proteins, thereby exposing the nuclear localization sequences that result in the activation of the receptor and initiation of the biological actions of the hormone on the target cell. In addition, recent work has demonstrated new pathways of steroid signaling through orphan and cell surface receptors that contribute to more rapid, “non-nuclear” or non-transcriptional effects of steroid hormones, often involving G-pro…

orphan receptorreceptorreceptorsandrogenBiologyprogesteronegenomic pathwaySettore BIO/10 - Biochimicaestrogensex steroid hormoneReceptorlcsh:Science (General)Orphan receptorHormone response elementsex steroid hormones; receptors; estrogens; androgens; progesterone; genomic pathway; non-genomic pathway; orphan receptorandrogensSex hormone receptornon-genomic pathwayBiochemistryNuclear receptorSex steroidHormone receptorsex steroid hormonesEstrogen-related receptor gammaestrogenslcsh:Q1-390AIMS Molecular Science
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"Sillä rahalla ei voi tulla toimeen jos ois kuinka hyvä laskupää" : punaorpojen avustaminen Kuopiossa 1918-1933

2014

Suomen sisällissota käytiin vuonna 1918, ja sen seurauksena kuoli noin 36 000 ihmistä ja yli 14 000 lasta jäi orvoiksi. Tässä pro gradu -tutkielmassa tarkastelen Kuopiossa sisällissodan seurauksena punaisten orvoiksi jääneitä lapsia. Tutkin, kuinka Kuopion kaupungin viranomaiset huolsivat punaorpoperheitä, ja vaikuttiko perheiden tausta avustustoimiin ja niiden toteuttamiseen. Kuopiossa punaorpopolitiikkaa toteutettiin erilaisessa kontekstissa kuin isommissa sodankärsineissä kaupungeissa. Kuopiossa oli sisällissodan jälkeen yhteensä 52 alle 15-vuotiasta punaorpoa. Tutkimukseni päälähteinä olen käyttänyt Kuopion kaupungin köyhäinhoitohallituksen ja -lautakunnan sekä kasvatus- ja lastensuojel…

orvot1930-lukuköyhäinhoitolastensuojelupunaorvotsosiaalihistoria1910-luku1920-lukuKuopiosisällissodatpaikallishistoria
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Biharmonic obstacle problem: guaranteed and computable error bounds for approximate solutions

2020

The paper is concerned with a free boundary problem generated by the biharmonic operator and an obstacle. The main goal is to deduce a fully guaranteed upper bound of the difference between the exact minimizer u and any function (approximation) from the corresponding energy class (which consists of the functions in $H^2$ satisfying the prescribed boundary conditions and the restrictions stipulated by the obstacle). For this purpose we use the duality method of the calculus of variations and general type error identities earlier derived for a wide class of convex variational problems. By this method, we define a combined primal--dual measure of error. It contains four terms of different natu…

osittaisdifferentiaaliyhtälöt010102 general mathematicsestimates of the distance to the exact solutionBoundary (topology)Function (mathematics)01 natural sciences010101 applied mathematicsComputational MathematicsIdentity (mathematics)aposteriori estimatesMathematics - Analysis of PDEsVariational inequalityObstacle problemFOS: MathematicsBiharmonic equationApplied mathematicsBoundary value problemapproksimointi0101 mathematics35J87 35J35epäyhtälötvariational inequalitiesAnalysis of PDEs (math.AP)MathematicsVariable (mathematics)
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