Search results for "PREP"

showing 10 items of 1334 documents

Cervical vertebral maturation and its relationship to circum-pubertal phases of the dentition in a cohort of Portuguese individuals

2019

Background To explore the relationship between individual skeletal maturity as assessed by Cervical Vertebral Maturity method (CVM), circum-pubertal phases of the dentition (early mixed, intermediate mixed, late mixed and early permanent) and chronlogical age in a cohort of Portuguese individuals. Material and Methods This was a retrospective cross-sectional study. The sample comprised 300 Caucasian Portuguese subjects aged 6 to 16 years, (137 boys and 163 girls). All the participants had good quality panoramic and lateral cephalometric radiographs. Subject skeletal maturity was evaluated using the CVM method. Dental age evaluation was determined by using panoramic radiographs and dental ca…

OrthodonticsDentitionbusiness.industryResearchOrthodonticsDental age:CIENCIAS MÉDICAS [UNESCO]language.human_languagemedicine.anatomical_structureLate mixed dentitionPrepubertal stageUNESCO::CIENCIAS MÉDICASCohortTooth CalcificationmedicinelanguagePortuguesebusinessGeneral DentistryCervical vertebraeJournal of Clinical and Experimental Dentistry
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Komparativno istraživanje oblikovanja četiriju rotirajućih sustava

2015

Svrha: U ovom istraživanju analizirali smo rezno područje, vrijeme instrumentacije, održavanje anatomije korijenskog kanala i neinstrumentirana područja dobivena korištenjem instrumenata F360®, Mtwo®, RaCe® i Hyflex® u ISO veličini 35. Materijali i metode: Odabrano je 120 zuba s jednim ravnim kanalom i podijeljeni su u četiri grupe. Radna duljina određena je radiološki. Zubi su rezani dijamantnim diskom, a presjeci su promatrani stereoskopskim mikroskopom Nikon SMZ-2T pod svjetiljkom Intralux 4000-1. Grupe su oblikovane predoperativnom analizom AutoCAD. Zubi su rekonstruirani s pomoću K-proširivača #10 i epoksi ljepila. Svaka grupa instrumentirana je jednim od četiriju sustava. Vrijeme inst…

OrthodonticsInstrumentationRoot canalTooth PreparationA diamondDental High-Speed Equipmentlcsh:RK1-715Light sourcemedicine.anatomical_structurelcsh:DentistryStereo microscopemedicineStatistical analysispreparacija korijenskog kanala brzo rotirajuća stomatološka oprema priprema zuba; poprečni presjecicross-sectionsRoot canal anatomyRoot Canal Preparation; Dental High-Speed Equipment; Tooth Preparation; cross-sectionsGeneral DentistryRoot Canal PreparationResearch ArticleMathematicsActa Stomatologica Croatica
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Comparison of Shaping Ability of 10 Rotary and Reciprocating Systems: an In Vitro Study with AutoCAD

2017

Cilj: Usporediti reznu površinu, očuvanje anatomije korijenskog kanala i neinstrumentiranu površinu nakon instrumentacije sustavima F360®, F6SkyTaper®, HyflexEDM®, iRace®, Neoniti®, O.Shape®, P.Next®, Reciproc®, Revo-S® i WaveOneGold® s veličinom instrumenta 25. Materijali i metode: Tristo zubi s jednim ravnim korijenom i okruglim ili eliptičnim presjekom korijenskog kanala podijeljeno je u 10 skupina (1-F360®, 2-F6SkyTaper®, 3-HyflexEDM®, 4-iRace®, 5-Neoniti®, 6-O Shape®, 7-P.Next®, 8-Reciproc®, 9-Revo-S® i 10-WaveOneGold®) i poprečno prerezano na trećine ultrafinim reznim diskovima. Uzorci su fotografirani pod stereomikroskopom i provedena je predinstrumentacijska analiza prije ponovnog s…

OrthodonticsRoot Canal Preparation; Dental HighSpeed EquipmentDental HighSpeed EquipmentRoot canal0206 medical engineering030206 dentistry02 engineering and technology020601 biomedical engineeringlcsh:RK1-715korijenski kanal priprema; brzo rotirajuća stomatološka oprema03 medical and health sciencesReciprocating motion0302 clinical medicinemedicine.anatomical_structurelcsh:DentistryCoronal planeStereo microscopemedicineIn vitro studyStatistical analysisOriginal Scientific PapersRoot canal anatomyGeneral DentistryRoot Canal PreparationMathematicsActa Stomatologica Croatica
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Accuracy of 4 digital scanning systems on prepared teeth digitally isolated from a complete dental arch

2018

Abstract Statement of problem The accuracy of digital scanners is acceptable for scanning a complete dental arch. However, whether that accuracy is sufficient for only 1 tooth within the dental scan of a complete dental arch is unclear. Purpose The purpose of this in vitro study was to evaluate and compare the accuracy of 4 intraoral scanners on a complete dental arch and on prepared teeth digitally isolated from the digital scan in terms of trueness and precision. Material and methods A model of a complete dental arch with tooth preparations was scanned 40 times with each of the 4 digital scanners. Their accuracy was evaluated by using 3-dimensional (3D) software to compare the test models…

OrthodonticsScannerDental Impression TechniqueComputer scienceDental Models030206 dentistryModels Dentalstomatognathic diseases03 medical and health sciencesDental archDental ArchImaging Three-Dimensional0302 clinical medicinemedicine.anatomical_structurestomatognathic systemmedicineComputer-Aided DesignDental Impression TechniqueTooth PreparationsOral SurgeryToothSoftwareThe Journal of Prosthetic Dentistry
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Canal shaping with a reciprocating system is easy to learn.

2018

To assess progressive learning of root canal shaping in order to define the number of simulated canals in resin blocks needed to reach a level of learning beyond which no further improvement in performance is observed.A total of 216 simulated canals in resin blocks were instrumented by 18 operators without experience in Endodontics and by 18 Endodontists. The R25 file of the Reciproc system (VDW, Munich, Germany) was used to prepare the canals. The blocks were photographed before and after instrumentation. An analysis was made of the variations in the dimensions of the canals at 6 locations and of the instrumentation time. A Student's t-test was used to analyse the data (P  0.05).The group …

Orthodonticsmedicine.medical_specialtyComputer scienceRoot canal0206 medical engineering030206 dentistry02 engineering and technologyDental educationEndodontics020601 biomedical engineeringEndodonticsRoot Canal Therapy03 medical and health sciencesReciprocating motion0302 clinical medicinemedicine.anatomical_structureGermanyotorhinolaryngologic diseasesmedicineHumanssense organsDental Pulp CavityGeneral DentistryRoot Canal PreparationInternational endodontic journal
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The Determination of Carbohydrates by High-Performance Anion-Exchange Chromatography Coupled with Pulsed Amperometric Detection (HPAEC-PAD)

2021

Chromatography techniques are widely used to separate, identify, and quantify molecules depending on their physicochemical properties. Standard methods range from simple size exclusion to separation based on affinity or ion exchange. Here, we present a method for the direct analysis of carbohydrates in Magnaporthe oryzae using high-performance anion-exchange chromatography (HPAEC) coupled with pulsed amperometric detection (PAD). The combination of HPAEC with PAD provides the highest selectivity and sensitivity with minimal sample preparation and cleanup time. Utilizing our HPAEC-PAD approach, we obtain reliable and highly reproducible determination of carbohydrates produced as osmotic stre…

Osmotic stress responseMagnaporthe oryzaeChromatographyIon exchangeChemistrySize-exclusion chromatographySample preparationStandard methodsDirect analysisAmperometry
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Preparation methods to optimize the performance of sensor discs for fast chemiluminescence ozone analyzers.

2013

Fast ozone (O(3)) measurements (1-50 Hz) in the atmosphere are required for airborne studies and for the measurement of ground-based O(3) fluxes by the eddy covariance technique. Fast response analyzers, based on heterogeneous chemiluminescence, need dye coated sensor discs on which the chemiluminescence is generated. In this study, we present three new preparation methods for those sensor discs. Currently available sensor discs exhibit a fast temporal decay of sensitivity, resulting in short duty times which is troublesome for many field applications. To produce sensor discs that provide more stable signals over time, three dyes and nine energy transfer reagents were tested (as well as dif…

OzoneLuminescent MeasurementsChemistryAnalytical chemistryGeneral Chemistrylaw.inventionPreparation methodMatrix (chemical analysis)chemistry.chemical_compoundAdsorptionOzoneEnergy TransferlawReagentLuminescent MeasurementsEnvironmental ChemistrySensitivity (control systems)Coloring AgentsChemiluminescenceEnvironmental sciencetechnology
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Six years of progress in the oral biopharmaceutics area - A summary from the IMI OrBiTo project.

2020

OrBiTo was a precompetitive collaboration focused on the development of the next generation of Oral Biopharmaceutics Tools. The consortium included world leading scientists from nine universities, one regulatory agency, one non-profit research organisation, three small/medium sized specialist technology companies together with thirteen pharmaceutical companies. The goal of the OrBiTo project was to deliver a framework for rational application of predictive biopharmaceutics tools for oral drug delivery. This goal was achieved through novel prospective investigations to define new methodologies or refinement of existing tools. Extensive validation has been performed of novel and existing biop…

PBPKEngineeringBest practicePharmaceutical ScienceAdministration Oral02 engineering and technology030226 pharmacology & pharmacyPermeabilityBiopharmaceutics03 medical and health sciences0302 clinical medicineDrug Delivery SystemsGastrointestinal drug absorptionDrug DevelopmentAnimalsHumansProspective StudiesIVIVCDrug absorptionbusiness.industryBiopharmaceuticsIndustrial researchGeneral Medicine021001 nanoscience & nanotechnologyGastrointestinal TractEngineering managementDrug developmentIntestinal AbsorptionPharmaceutical PreparationsNew product developmentRegulatory agency0210 nano-technologybusinessDissolutionOral retinoidBiotechnologyEuropean journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
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Determination of 40 currently used pesticides in airborne particulate matter (PM 10) by microwave-assisted extraction and gas chromatography coupled …

2011

A confirmatory and sensitive procedure has been developed for the determination of 40 currently used pesticides (Cups) in airborne particulate matter (PM 10) at trace level. The proposed method includes extraction of PM 10-bound pesticides by microwave-assisted extraction (MAE) followed by a gel permeation chromatography (GPC) clean-up and determination by GC-MS/MS. The injection mode and the main parameters in MS/MS were optimized. The matrix effect was also evaluated. Recoveries ranged from 70 to 120% except for pyrimethanil and pirimicarb. The limit of quantification (LOQ) ranged from 1.32 to 39.47 pg m(-3), when air volumes of 760 m(3) were collected. The method was applied to 38 sample…

PM 10Detection limitChromatographyExtraction (chemistry)BifenthrinPesticideBiochemistryAmbient airAnalytical Chemistrychemistry.chemical_compoundchemistryEnvironmental chemistryMicrowave-assisted extractionGas chromatography-mass spectrometryEnvironmental ChemistryPyrimethanilSample preparationGas chromatographyPesticidesGas chromatography–mass spectrometrySpectroscopyAnalytica Chimica Acta
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In Vitro Evaluation of the Squaramide-Conjugated Fibroblast Activation Protein Inhibitor-Based Agents AAZTA5.SA.FAPi and DOTA.SA.FAPi

2021

Recently, the first squaramide-(SA) containing FAP inhibitor-derived radiotracers were introduced. DATA5m.SA.FAPi and DOTA.SA.FAPi with their non-radioactive complexes showed high affinity and selectivity for FAP. After a successful preclinical study with [68Ga]Ga-DOTA.SA.FAPi, the first patient studies were realized for both compounds. Here, we present a new squaramide-containing compound targeting FAP, based on the AAZTA5 chelator 1,4-bis-(carboxylmethyl)-6-[bis-(carboxymethyl)-amino-6-pentanoic-acid]-perhydro-1,4-diazepine. For this molecule (AAZTA5.SA.FAPi), complexation with radionuclides such as gallium-68, scandium-44, and lutetium-177 was investigated, and the in vitro properties of…

PREPPharmaceutical ScienceAcetatesLutetiumLigands030218 nuclear medicine & medical imagingAnalytical ChemistrySerinechemistry.chemical_compoundQD241-4410302 clinical medicineFibroblast activation protein alphaPositron Emission Tomography Computed TomographyDrug Discoverylutetium-177AAZTA; scandium-44; lutetium-177; FAP; SA; DPP; PREPQuinineChemistrySerine EndopeptidasesAzepinesscandium-44ChemistryChemistry (miscellaneous)030220 oncology & carcinogenesisMolecular MedicineSelectivityDPPGallium RadioisotopesConjugated systemArticleHeterocyclic Compounds 1-Ring03 medical and health sciencesSAEndopeptidasesHumansDOTAChelationPhysical and Theoretical ChemistryBiologyAAZTARadioisotopesOrganic ChemistrySquaramideMembrane ProteinsFAPFibroblastsCombinatorial chemistryIn vitroRadiopharmaceuticalsScandiumMolecules
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