Search results for "Platinum"
showing 10 items of 629 documents
Structural studies on 2-pyridyl complexes of the platinum triad metals. The crystal and molecular structure of the 2-pyridylium derivative trans-[PdC…
1991
Abstract In solution, the complex trans -[PdCl(C 5 H 4 N C 2 )(PMe 2 Ph) 2 ] ( 1 ) is in equilibrium with a small amount of the binuclear species [{PdCl(μ-C 5 H 4 N C 2 , N )(PMe 2 Ph)} 2 ] ( 2 ), which can be isolated upon recrystallization. The compound 1 is easily N-protonated by HClO 4 to the 2-pyridylium product trans -[PdCl(C 5 H 5 N C 2 )(PMe 2 Ph) 2 ]ClO 4 ( 3 ), which crystallizes in the orthorhombic space group P2 1 2 1 2 1 , with cell parameters a =15.761(3), b =14.369(2), c =11.132(2) A and Z =4. The X-ray crystal structure analysis of 3 , using 3744 observed reflections in the refinement and resulting in a final R value of 0.0298, shows that the coordination around palladium…
Coordination properties of imino(2-pyridyl)methylpalladium(II) compounds. Preparation and thermal rearrangement of binuclear adducts with palladium(I…
1988
Abstract The imino(2-pyridyl)methylpalladium(II) compound py-2-C(R′)NR (R = C 6 H 4 OMe-p, R′ = trans-PdCl(PPh 3 ) 2 ) reacts with [PdCl 2 (CH 2 CHPh)] 2 , [PdCl 2 - (NCMe) 2 ], and K[PtCl 3 (CH 2 CH 2 )] to give binuclear complexes [MCl 2 {py-2- C(R′)NR}] (M = Pd, Pt), in which the α-diimino group acts as a chelating bidentate ligand. In hot 1,2-dichloroethane, these complexes undergo a PPh 3 and chloride ligand exchange at rates which depend markedly on the metal M (Pd ⪢ Pt), to yield the new derivatives [MCl(PPh 3 ){py-2-C(cis-PdCl 2 (PPh 3 ))NR}]. The ligand exchange is followed by a much slower decomposition to [MCl 2 (PPh 3 ) 2 ]. Labile intermediates of the same type, [MCl(PPh …
Five-coordinate complexes of palladium(ii) and platinum(ii) with α-diimine and 1,5-cyclooctadiene ligands
2001
The five-coordinate complexes [PtMe(cod)(N–N′)]BF4 [cod = η2,η2-cyclooctadiene, N–N′ = (6-R2)C5H3N-2-CHNR1 (R1 = C6H4OMe-4, R2 = H (1), Me (2); R1 = CMe3, R2 = H (3), Me (4); R1 = (R)-bornyl, R2 = Me (5))] are readily obtained from the reaction of [PtClMe(cod)] with N–N′ in the presence of NaBF4. The preparation of [PtMe(cod)(6)]BF4 (6 = 4-MeOC6H4NCHCHNC6H4OMe-4), [PdMe(cod)(N–N′)]BF4 and [PtCl(cod)(N–N′)]BF4 (N–N′ = 2, 4) requires chloride abstraction by AgBF4 from [PtClMe(cod)], [PdClMe(cod)] and [PtCl2(cod)], respectively, followed by coordination of N–N′. The NMR spectral data suggest a trigonal-bipyramidal structure with chelating cod and N–N′ ligands, where the α-diimine and one CC bo…
Synthesis, properties, antitumor and antibacterial activity of new Pt(II) and Pd(II) complexes with 2,2′-dithiobis(benzothiazole) ligand
2017
Mono- and binuclear Pt(II) and Pd(II) complexes with 2,20-dithiobis(benzothiazole) (DTBTA) ligand are reported. [Pt(DTBTA)(DMSO)Cl]Cl∙CHCl3 (1) and [Pd2(m-Cl)2(DTBTA)2]Cl2 (2) have been synthesized and structurally characterized by elemental analysis, IR, 1H and 13C NMR spectroscopy, MS spectrometry and the content of platinum and palladium was determined using a flame atomic spectrometer. Two different coordination modes of 1 and 2 complexes were found; in both complexes, the coordination of Pt(II) and Pd(II) ions involves the N(3) atoms of the ligand but the binuclear complex 2, is a cis-chloro-bridged palladium complex. Evaluation of their in vitro antitumor activity against two human tu…
Cytotoxicity and NMR Studies of Platinum Complexes with Cyclooctadiene Ligands
2014
The synthesis of a series of platinum complexes containing cyclooctadiene ligands with the general structure PtMeL(R-cod) (where L = Cl, I, nC3F7, iC3F7, nC8F17, Me, aryl, alkynyl and R = H, Me, Et, iPr, nBu, iBu, nHex, Ph) is presented. All complexes are remarkably stable and were obtained in excellent yields. Their structure in both solution and the solid state were explored by crystal structures and multinuclear (1H, 13C, 19F, 195Pt) NMR spectroscopy. Cytotoxicity experiments with selected complexes in HeLa cells revealed higher toxicity in comparison to that of cisplatin for most of the structures.
A sterically congested 1,2-diphosphino-1'-boryl-ferrocene: synthesis, characterization and coordination to platinum.
2019
International audience; A new class of tritopic ferrocene-based ambiphilic compound has been prepared by assembling diphosphino- and boryl-substituted cyclopentadienides at iron. The presence of five sterically demanding substituents on the ferrocene platform induces conformation constraints, as apparent from XRD and NMR data, but does not prevent chelating coordination to platinum. The Lewis acid moiety is pendant in both the free ligand and the platinum complex.
Self-Sorting Effects in the Self-Assembly of Metallosupramolecular Rhombi from Chiral BINOL-Derived Bis(pyridine) Ligands
2013
Four BINOL-based bis(4-pyridyl) ligands were synthesised in enantiopure and racemic form. These ligands form metallosupramolecular [(dppp)2M2L2] rhombi with cis-protected [(dppp)Pd]2+ and [(dppp)Pt]2+ ions. In principle, racemic ligands can self-assemble into three stereoisomeric rhombi. The degree of self-sorting in the self-assembly process crucially depends on the substitution pattern and the resulting bend angle of the V-shaped ligands as well as the degree of steric crowding within the assembly when racemic ligands are used. Thus, these processes either lead to homochiral assemblies in a narcissistic self-recognition manner, to heterochiral assemblies in a social self-discriminating ma…
Synthesis, structural characterisation and biological studies of new mononuclear platinum(II) complexes with sterically hindered heterocyclic ligands
2011
Abstract Three novel cisplatin analogues were synthesized, designed according to an approach which violates the “classical” structure–activity relationship, by replacing the diamine ligands with a planar N donor heterocycle giving a sterically hindered complex. Moreover, the sterical hindrance of antitumor drug candidates potentially makes them less susceptible to deactivation by sulphur-containing proteins and helping to overcome resistance mechanisms. The resulting mononuclear complexes of sterically hindered polidentate heterocyclic N ligands [PtCl(bbp)]Cl ( 1 ) [bbp = 2,6-bis(2-benzimidazolyl)pyridine], [PtCl 2 (dptdn)](H 2 O) ( 2 ) [dptdn = sodium 5,6-diphenyl-3-(2′-pyridyl)-1,2,4-tria…
CCDC 881313: Experimental Crystal Structure Determination
2013
Related Article: A.N.Chernyshev, N.A.Bokach, P.V.Gushchin, M.Haukka, V.Yu.Kukushkin|2012|Dalton Trans.|41|12857|doi:10.1039/c2dt30986f
Influence of sample pan on the thermal behaviour of KSCN measured with TG
2003
Abstract In this study, the influence of the sample pan on the thermal behaviour of potassium thiocyanate (KSCN) was investigated. The measurements were performed with thermogravimetry (TG) and the two sample pans used were a platinum pan and a ceramic crucible. The samples were heated to 400–950 °C and the thermal products were identified by powder diffraction. The thermal behaviour of KSCN was found to be dependent on the sample pan used. With the platinum sample pan KSCN reacted in the first step into a mixture of K 2 SO 4 and potassium tetracyanoplatinate (K 2 Pt(CN) 4 ). In the second step, the mixture reacted further to pure K 2 SO 4 . In the ceramic sample crucible, however, the reac…