Search results for "Positive"

showing 10 items of 1875 documents

Liver Steatosis and Fibrosis in OSA patients After Long-term CPAP Treatment: A Preliminary Ultrasound Study.

2015

In cases of morbid obesity, obstructive sleep apnea (OSA) was associated with biopsy-proven liver damage. The role of non-invasive techniques to monitor liver changes during OSA treatment with continuous positive airway pressure (CPAP) is unknown. We used non-invasive ultrasound techniques to assess liver steatosis and fibrosis in severe OSA patients at diagnosis and during long-term CPAP treatment. Fifteen consecutive patients with severe OSA (apnea hypopnea index 52.5 ± 19.1/h) were studied by liver ultrasound and elastography (Fibroscan) at 6-mo (n = 3) or 1-y (n = 12) follow-up. Mean age was 49.3 ± 11.9 y, body mass index (BMI) was 35.4 ± 6.4 kg/m(2). Adherence to CPAP was ≥5 h/night. A…

Liver CirrhosisMalemedicine.medical_specialtyAcoustics and Ultrasonicsmedicine.medical_treatmentBiophysicsSettore MED/10 - Malattie Dell'Apparato RespiratorioGastroenterologyBody Mass IndexTime03 medical and health sciences0302 clinical medicineFibrosisInternal medicinemedicineHumansRadiology Nuclear Medicine and imagingObesityContinuous positive airway pressureNon-invasive assessmentUltrasonographySleep Apnea ObstructiveRadiological and Ultrasound Technologymedicine.diagnostic_testContinuous Positive Airway Pressurebusiness.industryFatty liverLiver fibrosiMiddle Agedmedicine.diseaseObstructive sleep apneanervous system diseasesrespiratory tract diseasesSurgeryObstructive sleep apneaFatty Liver030228 respiratory systemApnea–hypopnea indexLiverLiver steatosiFeasibility Studies030211 gastroenterology & hepatologyFemaleElastographyLongitudinal studySteatosisbusinessBody mass indexUltrasound in medicinebiology
researchProduct

Changing aetiological factors of hepatocellular carcinoma and their potential impact on the effectiveness of surveillance

2011

BACKGROUND: The aetiological factors of hepatocellular carcinoma may vary over time. AIMS: The study assessed the potential impact of the aetiological factors on the effectiveness of surveillance in real-world patients. METHODS: Multicentre, cross-sectional study enrolling consecutive hepatocellular carcinoma cases during a six month period. RESULTS: 1733 cases (1311 prevalent and 422 incident) were recruited (mean age 68.6 years; 46.1% cases over 70 years; 73.9% males; 95.3% with cirrhosis); 63.0% were hepatitis C virus positive and 23.7% were virus negative. Amongst incident HCCs, 34.5% were single ≤3cm and 54.4% met the Milan criteria; 61.6% were diagnosed during surveillance; virus nega…

Liver CirrhosisMalemedicine.medical_specialtyCarcinoma HepatocellularEpidemiologyHepatocellular carcinomaCross-sectional studyCancer stageCancer stage; Epidemiology; Hepatitis; Hepatocellular carcinoma; Surveillance; Age Distribution; Aged; Carcinoma Hepatocellular; Cross-Sectional Studies; Female; Hepatitis B Surface Antigens; Hepatitis C Antibodies; Humans; Incidence; Italy; Liver Cirrhosis; Liver Neoplasms; Logistic Models; Male; Middle Aged; Multivariate Analysis; Prevalence; Ultrasonography; Population Surveillance; Hepatology; GastroenterologyMilan criteriaHepatitisAge DistributionInternal medicineEpidemiologyPrevalenceCarcinomaHumansMedicineHCCAgedUltrasonographyHepatitisHepatitis B Surface AntigensSurveillanceHepatologybusiness.industryIncidenceIncidence (epidemiology)CarcinomaLiver NeoplasmsCancer stage Epidemiology Hepatitis Hepatocellular carcinoma SurveillanceGastroenterologyHepatocellularHepatitis C AntibodiesMiddle Agedmedicine.diseaseETIOLOGYSurgeryCross-Sectional StudiesLogistic ModelsItalyHepatitis C Virus PositivePopulation SurveillanceHepatocellular carcinomaMultivariate AnalysisSURBVEILLANCEFemalebusiness
researchProduct

Spontaneous Bacterial Peritonitis: A Prospective Investigation in Predominantly Nonalcoholic Cirrhotic Patients

1983

Two hundred and twenty-four consecutive inpatients with cirrhosis, mostly of nonalcoholic etiology, and ascites were prospectively investigated on admission for spontaneous bacterial peritonitis (SBP) by culture, smear, and polymorphonuclear (PMN) counts of ascitic fluid. Positive cultures were found in 54 patients. A possible intraabdominal source of infection was apparent in five of them, all with clinically overt peritonitis (secondary peritonitis). No intraabdominal source of infection was identified in the remaining 49. These patients were classified into the following groups: (a) SBP, 27 patients (positive cultures plus PMN counts ± 250 per mm3). Nine of them had no clinical features …

Liver CirrhosisMalemedicine.medical_specialtyCirrhosismedicine.drug_classAntibioticsPeritonitisPeritonitisGastroenterologySpontaneous bacterial peritonitisInternal medicineAscitesHumansMedicineProspective StudiesProspective cohort studyAgedHepatologybusiness.industryAscitesBacterial InfectionsMiddle Agedmedicine.diseaseSurgeryEtiologyPositive cultureFemalemedicine.symptombusinessHepatology
researchProduct

Characteristics of HCV positive subjects referring to hospitals in Italy: a multicentre prevalence study on 6,999 cases.

2006

In 2001, 6,999 anti-HCV positive subjects referred to 79 Italian hospital in a 6 months enrollment period were evaluated. Of them, 5,632 (80.5%) tested anti-HCV positive alone, 1,163 (16.6%) reported also an excessive alcohol intake, and 204 (2.9%) were also HBsAg positive. Normal biochemistry was observed in 7.8% of cases, chronic hepatitis in 67.9% of cases, liver cirrhosis in 18.9% of cases, and hepatocellular carcinoma in 3.6% cases. HCV positive subjects with excessive alcohol intake were statistically significantly younger, of male sex, and having more severe liver disease than those without excessive alcohol intake. Adjusting for the confounding effect of age and sex by multiple logi…

Liver CirrhosisMalemedicine.medical_specialtyHBsAgCirrhosisCarcinoma HepatocellularAlcohol DrinkingHepacivirusHepacivirusChronic liver diseaseHCV PositiveLiver diseaseVirologyInternal medicinePrevalenceMedicineHumansHepatologybiologybusiness.industryIncidence (epidemiology)Incidencechronic liver diseaseHepatitis C ChronicMiddle Agedbiology.organism_classificationmedicine.diseaseSurgeryHCV infectionInfectious DiseasesItalyHepatocellular carcinomaRegression AnalysisFemalebusinessJournal of viral hepatitis
researchProduct

Ultrasonography and alpha-fetoprotein in diagnosis of hepatocellular carcinoma in cirrhosis

1988

The accuracy of ultrasound (US) and alpha-fetoprotein (AFP) in the diagnosis of hepatocellular carcinoma (HCC) in 363 patients with cirrhosis (C) and a clinical suspicion of HCC was assessed. The ultrasonographic patterns of HCC and their relationship with AFP values were analyzed. Echographic patterns were distributed as follows: 47 patients had sonodense lesions; 30 patients had hypoechoic lesions; 47 had mixed-pattern lesions, and in four patients focal dilated intrahepatic bile ducts were demonstrated. The sensitivity of US was 90%; specificity was 93.3%. Serum AFP level greater than or equal to 500 ng/ml (RIA) was the first clue to the diagnosis in 71 patients (48.6%); specificity was …

Liver CirrhosisMalemedicine.medical_specialtyPathologyCarcinoma HepatocellularCirrhosisPhysiologySensitivity and SpecificityGastroenterologyTransplant surgeryDilated intrahepatic bile ductsInternal medicineHumansMedicineFalse Positive ReactionsProspective StudiesFalse Negative ReactionsneoplasmsUltrasonographybusiness.industryLiver NeoplasmsUltrasoundGastroenterologyHepatologymedicine.diseasedigestive system diseasesHepatocellular carcinomaFemalealpha-FetoproteinsUltrasonographybusinessAlpha-fetoproteinAlgorithmsDigestive Diseases and Sciences
researchProduct

Acarbose-induced liver injury in an anti-hepatic C virus positive patient

2001

Liver injurymedicine.medical_specialtyHepatologybusiness.industryGastroenterologymedicine.diseasePositive patientGastroenterologyVirusInternal medicinemedicinebusinessAcarbosemedicine.drugDigestive and Liver Disease
researchProduct

Pre-conception maternal helminth infection transfers via nursing long-lasting cellular immunity against helminths to offspring

2019

Mothers transfer immune cells via breastfeeding to provide offspring with long-term protection from parasitic infection.

Long lastingCD4-Positive T-LymphocytesMaleCellular immunityOffspring[SDV]Life Sciences [q-bio]animal diseasesImmunologyAntibodies Helminthchemical and pharmacologic phenomenaReceptors Cell SurfaceBiology03 medical and health sciences0302 clinical medicineImmune systemTh2 CellsNursingImmunityPregnancymedicineHelminthsAnimalsLactationImprinting (psychology)Research Articles030304 developmental biologyStrongylida Infections0303 health sciencesPregnancyB-LymphocytesImmunity CellularMice Inbred BALB CMultidisciplinarySciAdv r-articlesbiochemical phenomena metabolism and nutritionmedicine.disease3. Good healthAnimals SucklingMice Inbred C57BLbacteriaFemaleNippostrongylusImmunity Maternally-Acquired030215 immunologyResearch ArticleScience Advances
researchProduct

The role of information and communication technologies in the relationship between group potency and group maintenance outcomes: a longitudinal study

2013

Group potency is one of the major factors influencing work group success. However, little is known about the effects of potency on group maintenance outcomes, especially in virtual teams. The present study examines the moderating role of information and communication technologies ICTs in the relationships between potency and group maintenance outcomes in a longitudinal study. The study involved 44 groups of four members each, working in two communication media: face-to-face F-t-F and computer-mediated communication CMC. The groups developed a project during four weekly sessions over a 1-month period. The results showed that ICTs moderated the relationship between potency and maintenance out…

Longitudinal studyGroup (mathematics)General Social SciencesModerationDevelopmental psychologyHuman-Computer InteractionGroup maintenanceArts and Humanities (miscellaneous)Information and Communications TechnologyDevelopmental and Educational PsychologyPotencyPositive relationshipICTSPsychologySocial psychologyBehaviour & Information Technology
researchProduct

Gendered pathways to romantic attachment in emerging adults: The role of body image and parental support

2015

This study analyses the impact of body image and perceived parental behaviour (support and negativity) as factors that contribute to romantic attachment in emerging adulthood. In a 11-year longitudinal study on 144 females and 114 males, we assessed body image, body mass index, and perceived father's and mother's support and negativity during adolescence (at ages 14 and 17) and in emerging adulthood (age 21). At the age of 25, romantic attachment was assessed. Results of path analyses revealed that females' positive body image was consistently linked with greater parental support over time and contributed to low avoidance in romance at the age of 25, whereas perceived negativity with father…

Longitudinal studyPositive body imageParental supportSocial PsychologyDevelopmental and Educational PsychologyNegativity effectYoung adultPsychologyRomanceBody mass indexDevelopmental psychologyEuropean Journal of Developmental Psychology
researchProduct

2020

Nasal continuous positive airway pressure (NCPAP) devices using variable (vf-) and continuous (cf-) flow or synchronized nasal intermittent positive pressure ventilation (s-NIPPV) are used to prevent or treat intermittent hypoxia (IH) in preterm infants. Results concerning which is most effective vary. We aimed to investigate the effect of s-NIPPV and vf-NCPAP compared to cf-NCPAP on the rate of IH episodes. Preterm infants with a gestational age of 24.9–29.7 weeks presenting with IH while being treated with cf-NCPAP were monitored for eight hours, then randomized to eight hours of treatment with vf-NCPAP or s-NIPPV. Data from 16 infants were analyzed. Due to an unexpectedly low sample size…

Longitudinal studybusiness.industrymedicine.medical_treatmentGestational ageIntermittent hypoxiaRespiratory supportIntermittent positive pressure ventilationVery pretermSample size determinationAnesthesiaPediatrics Perinatology and Child HealthMedicineContinuous positive airway pressurebusinessChildren
researchProduct