Search results for "Quality Control"
showing 10 items of 180 documents
Data for nine autosomal STRs markers from Valencia (East Mediterranean coast of the Iberian Peninsula)
2000
Nine STRs loci have been typed in a sample from Valencia, a population from the East Mediterranean coast of the Iberian Peninsula.
A report of an international collaborative experiment to demonstrate the uniformity obtainable using DNA profiling techniques
1992
This paper describes a collaborative exercise intended to demonstrate whether uniformity of DNA profile results could be achieved between different European laboratories. It was shown that this goal can be obtained provided that a common protocol is followed (specifically the use of a common electrophoretic buffer as being the most important parameter). Generally, lower molecular weight loci (with lower molecular weight fragments) such as YNH24 perform better than higher molecular weight loci such as MS43a. The results of the exercise are discussed in relation to the objectives of the European DNA profiling group (EDNAP).
Artificial chromosome libraries of Streptomyces coelicolor A3(2) and Planobispora rosea
2003
Using an Escherichia coli-Streptomyces shuttle vector derived from a bacterial artificial chromosome (BAC), we developed methodologies for the construction of BAC libraries of filamentous actinomycetes. Libraries of Streptomyces coelicolor, the model actinomycete, and Planobispora rosea, a genetically intractable strain, were constructed. Both libraries have an average insert size of 60 kb, with maximal insert larger than 150 kb. The S. coelicolor library was evaluated by selected hybridisations to DraI fragments and by end sequencing of a few clones. Hybridisation of the P. rosea library to selected probes indicates a good representation of the P. rosea genome and that the library can be u…
Determination of 3-MCPD by GC-MS/MS with PTV-LV injector used for a survey of Spanish foodstuffs
2007
3-Monochloropropane-1,2-diol (3-MCPD) is the most common chemical contaminant of the group of chloropropanols. It can occur in foods and food ingredients at low levels as a result of processing, migration from packaging materials during storage and domestic cooking. A sensitive method for determination of 3-MCPD in foodstuffs using programmable temperature vaporization (PTV) with large-volume injection (LVI) gas chromatography (GC) with tandem mass spectrometry detection (MS/MS) has been developed and optimized. The optimization of the injection and detection parameters was carried out using statistical experimental design. A Plackett-Burman design was used to estimate the influence of reso…
Control cuantitativo de la calidad en una empresa del sector servicios = Quantitative quality control in a company of the service industry
2013
<p>En el presente trabajo se aplican herramientas de Control Estadístico de Calidad, habitualmente utilizadas en procesos productivos, a una empresa dedicada a la auditoría y que por tanto pertenece al sector servicios. La elección de las herramientas utilizadas (gráficos de control, indicadores de capacidad, función de pérdida de Taguchi…) obedece a la necesidad de controlar si se cumple el objetivo de la empresa de realizar la auditoría a la empresa cliente 7 días antes de la fecha teórica, lo que conlleva una disminución de costes. También se cuantifica la pérdida que produce el incumplimiento de dicho objetivo y se proponen medidas correctoras que disminuyen la variabilidad del pr…
Technical and health governance aspects of the External Quality Assessment Scheme for the SARS-CoV-2 molecular tests: institutional experience perfor…
2022
Abstract Objectives Since December 2019, the worldwide public health has been threatened by a severe acute respiratory syndrome caused by Coronavirus-2. From the beginning, a turning point has been the identification of new cases of infection, in order to minimize the virus spreading among the population. For this reason, it was necessary introducing a panel of tests able to identify positive cases, which became crucial for all countries. Methods As a Regional Reference Centre, the CRQ Laboratory (Regional Laboratory for the Quality Control) developed and conducted an External Quality Assessment (EQA) panel of assay, so as to evaluate the quality of real-time reverse transcription polymeras…
The expected value of the traceability information
2015
Abstract Recent regulations on agri-food traceability prescribe traceability throughout the entire supply chain, in order to ensure consumers’ safety and product quality. This has led producers and retailers to consider the opportunity to improve the firm's reputation and consumer confidence through the implementation of traceability systems designed not only to satisfy the legal requirements, but also to track the quality of the products through the supply chain for optimization purposes. However the actual implementation of such systems depends on the possibility of gathering specific information related to the product quality. Nowadays, innovative and non invasive technologies such as th…
Quality for Global Knowledge-Intensive Organizations: A Step-by-Step Guide
2009
Learning and education as well as knowledge-intensive work processes have become more and more internationalized. Knowledge workers are distributed around the world, study programs are exported across borders, and learners work in globally distributed groups. However, the quality of their work differs in many cases. In this paper, an approach to manage quality within the process of internationalization for globally distributed knowledge-intensive organizations (such as universities) is presented. A particular focus is the field of e-Learning. The key quality factors for internationalization of global learning are defined and examples for quality criteria resulting from these factors are int…
Effects of gamma-irradiation on trehalose–hydroxyethylcellulose microspheres loaded with vancomycin
2003
Ionizing radiation can be used as a drug sterilization technique, provided that the drug itself is not modified and that no toxic products are produced; moreover, if the irradiated product is a drug delivery system, the drug release characteristics must not be significantly altered by radiation. The aim of this work was to study the effects of sterilization by ionizing radiation on hydroxyethylcellulose/trehalose spherical micromatrices, containing the antibiotic vancomycin. Our experimental results showed that gamma-rays did not alter the chromophore groups of vancomycin (UV measurements), and did not modify the kinetic behavior of drug release from microspheres. Moreover, no significant c…
Autoantibody detection using indirect immunofluorescence on HEp-2 cells
2009
The detection of autoantibodies is an important element in the diagnosis and monitoring of disease progression in patients with autoimmune diseases. In laboratory diagnostic tests for connective tissue and autoimmune liver diseases, indirect immunofluorescence on HEp-2 cells plays a central role in a multistage diagnostic process. Despite the high quality of diagnostics, findings at different laboratories can differ considerably due to a lack of standardization, as well as subjective factors. The present paper formulates recommendations for the standardized processing and interpretation of the HEp-2 cell test for the detection of non-organ-specific (especially antinuclear) antibodies. It pr…