Search results for "RATES"
showing 10 items of 1636 documents
La politique sportive des Emirats du Golfe : comment obtenir une visibilité internationale ?
2006
Les petits Emirats du Golfe Persique ont choisi le sport pour obtenir une visibilité internationale et modifier leur image. Le sport offrait la possibilité d’afficher une modernité souvent associée à l’adoption de valeurs venues de l’Occident. Sans traditions sportives et très peu peuplés, ces Etats ont néanmoins réussi leur entrée sur la scène sportive internationale en mobilisant beaucoup d’argent. Ils ont pu ainsi accueillir et organiser des compétitions sportives internationales de grande ampleur et se faire reconnaître. Leur politique a franchi un nouveau pas, depuis quatre années, en naturalisant des athlètes de haut niveau pour obtenir des médailles car en terme de communication, l’i…
Retinoids as a Perspective in Treatment of Alzheimer’s Disease
2010
<i>Background:</i> In the past, we demonstrated that the disintegrin metalloproteinase ADAM10 has α-secretase activity in vitro and in cultured cells. We also found out that moderate overexpression of this proteinase inhibits Aβ peptide production and prevents the formation of amyloid plaques in an Alzheimer’s disease (AD) mouse model. Moreover, it corrects early hippocampal defects like LTP impairment and increases cortical synaptogenesis. <i>Objective:</i> Upregulation of ADAM10 might be an alternative approach concerning AD therapy. Our current research therefore focuses on substances and/or pathways which regulate ADAM10 gene expression. <i>Methods:</i&g…
Binding Properties and Stability of the Ras-Association Domain of Rap1-GTP Interacting Adapter Molecule (RIAM)
2012
The Rap1-GTP interacting adapter protein (RIAM) is an important protein in Rap1-mediated integrin activation. By binding to both Rap1 GTPase and talin, RIAM recruits talin to the cell membrane, thus facilitating talin-dependent integrin activation. In this article, we studied the role of the RIAM Ras-association (RA) and pleckstrin-homology (PH) domains in the interaction with Rap1. We found that the RA domain was sufficient for GTP-dependent interaction with Rap1B, and the addition of the PH domain did not change the binding affinity. We also detected GTP-independent interaction of Rap1B with the N-terminus of RIAM. In addition, we found that the PH domain stabilized the RA domain both in …
Studies on zymogenicity and solubilization of chitin synthase from Candida albicans
1985
The zymogenic form of the chitin synthase present in mixed membrane preparations was extracted by digitonin treatment. The residual extracted membranes exclusively retained the basal activity. Trypsin activation of the zymogenic form of the enzyme did not modify the digitonin solubilization characteristics of the original zymogenic form, suggesting significant differences between ‘in vivo’ activation of chitin synthase and that carried out by trypsin ‘in vitro’.
Data for: Microstructural analysis (Voigt function method) of mullite in whiteware triaxial porcelains.
2020
X-Ray powder diffraction profile data , for the studied samples THIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE. TO VIEW A LIST OF FILES AND ACCESS THE FILES IN THIS DATASET CLICK ON THE DOI-LINK ABOVE
Caracterización de complejos enzimáticos histona acetiltransferasa en Saccharomyces cerevisiae mediante el uso de mutantes en genes implicados en la …
1999
En la cromatina de los organismos eucariotas el DNA se organiza alrededor de octámeros de histonas, dando lugar a la estructura nucleosomal. Las histonas sufren una serie de modificaciones postraduccionales entre las que se encuentra la acetilación de residuos de lisina, situados en los extremos N-terminales de estas proteínas. Esta modificación reversible, catalizada in vivo por las histona desacetilasas (HD) y las histona acetiltransferasas (HAT), ha sido implicada durante muchos años en la regulación de diversos procesos celulares de gran importancia. Recientemente, el papel de la acetilación de histonas en la regulación de la transcripción ha cobrado gran importancia con el descubrimien…
Las nuevas excavaciones (1995-2006) en el yacimiento del Mioceno final de Venta del Moro, Valencia
2006
13 páginas, 5 figuras, 2 láminas, 1 tabla.
Structural analysis, phase stability and electrochemical characterization of Nb doped BaCe0.9Y0.1O3−x electrolyte for IT-SOFCs
2012
Abstract To improve the chemical stability of high temperature proton conductors based on barium cerate, electrolyte powders doped with different amounts of niobium were synthesized by the citrate–nitrate auto-combustion method. Pure single phases of BaCe 0.9− x Nb x Y 0.1 O 3− x (BCYN, 0.03 ≤ x ≤ 0.12) were obtained by thermal treatment at 1000 °C. Sintering at 1450 °C for 10 h produced dense pellets. X-ray absorption spectroscopy allowed to define the dopant ion insertion site and the co-dopant valency. Treatments in pure CO 2 atmosphere at 700 °C for 3 h and subsequent XRD analysis were carried out to probe the chemical stability of the produced electrolytes. The influence of the prese…
Due democratiche cristiane alla Consulta nazionale: Laura Bianchini e Angela Maria Guidi Cingolani
2022
Questo articolo appartiene a uno studio più ampio che mira a ricostruire una tradizione politica femminile per comprendere alcune delle ragioni persistenti dietro il divario di genere tra accesso formale e sostanziale alle decisioni. L’obiettivo finale è quello di evidenziare il ruolo e il contributo delle donne, soprattutto di quelle che sono finite nell’oblio, nella costituzione di un’Italia democratica e repubblicana fin dalle loro prime partecipazioni all’Assemblea Nazionale Consultiva. L’Archivio della Camera dei Deputati, l’Archivio dell’Istituto Sturzo e gli articoli delle riviste dell’epoca sono state le fonti primarie della ricerca.Il 25 settembre 1945 si inaugura la Consulta che r…
Preliminary report on the microvertebrate faunal remains from the Late Triassic locality at Krasiejów, SW Poland
2019
Fossil vertebrate remains from the Keuper unit in the vicinity of the village of Krasiejów have been analyzed for almost two decades. However, the main goal of these works was focused mainly on large vertebrates. Here the authors present the first description of microvertebrate fossils from that site. The collection of around 5,000 specimens is mainly comprised of teeth and scales. The most numerous remains belong to osteichthyans: dipnoans (Ptychoceratodus and cf. Arganodus), palaeoniscids, semionotids, redfieldiids and chondrichthyans, such as Lonchidion sp., which is the first indisputable record of that genus in the Upper Triassic of Poland and the first shark at the Krasiejów locality.…