Search results for "Response surface methodology"

showing 10 items of 50 documents

Impact of Pressurized Liquid Extraction and pH on Protein Yield, Changes in Molecular Size Distribution and Antioxidant Compounds Recovery from Spiru…

2021

The research aims to extract nutrients and bioactive compounds from spirulina using a non-toxic, environmentally friendly and efficient method—Pressurized Liquid Extraction (PLE). In this work, Response Surface Methodology (RSM)–Central Composite Design (CCD) was used to evaluate and optimize the extraction time (5–15 min), temperature (20–60 °C) and pH (4–10) during PLE extraction (103.4 bars). The multi-factor optimization results of the RSM-CCD showed that under the pressure of 103.4 bars, the optimal conditions to recover the highest content of bioactive compounds were 10 min, 40 °C and pH 4. Furthermore, the compounds and antioxidant capacity of PLE and non-pressurized extraction extra…

0106 biological sciencesHealth (social science)AntioxidantPLEmedicine.medical_treatmentTP1-1185Plant Science01 natural sciencesHealth Professions (miscellaneous)MicrobiologyArticleCinnamic acidchemistry.chemical_compoundTriple TOF–LC–MS–MS0404 agricultural biotechnology010608 biotechnologymedicineResponse surface methodologySodium dodecyl sulfatePolyacrylamide gel electrophoresisCarotenoidRSM-CCDchemistry.chemical_classificationbioactive compoundsChromatographyChemical technologymicroalgaeExtraction (chemistry)04 agricultural and veterinary sciences040401 food science6. Clean waterchemistryPolyphenolSDS-PAGEFood ScienceFoods
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Influence of pulsed electric field processing on the quality of fruit juice beverages sweetened with Stevia rebaudiana

2017

Abstract A fruit juice-stevia beverage was processed using pulsed electric fields (PEF), a non-thermal preservation technology, with the purpose of investigating the feasibility of PEF for bioactive compounds and steviol glycosides enhancement and its impact on physicochemical properties. Variable ranges of response surface methodology were 20–40 kV/cm (electric field strength), 100–360 μs (treatment time) and 0–2.5% (w/v) stevia. After PEF, ascorbic acid was retained by more than 74%. Some of the analyzed PEF treatments resulted in an enhancement of total anthocyanins and carotenoids. The best results for rebaudioside A/stevioside ratio were obtained when PEF was applied at 30 kV/cm for 23…

0106 biological scienceschemistry.chemical_classificationChemistryGeneral Chemical EngineeringGlycosideSteviol04 agricultural and veterinary sciencesAscorbic acid040401 food science01 natural sciencesBiochemistrychemistry.chemical_compoundStevia rebaudiana0404 agricultural biotechnology010608 biotechnologySteviosideFood scienceResponse surface methodologyRebaudioside AHydroxymethylfurfuralFood ScienceBiotechnologyFood and Bioproducts Processing
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Analysis of optimal temperature, pressure and binder quantity for the production of biocarbon pellet to be used as a substitute for coke

2019

In order to contribute to the decarbonization of the economy, efficient alternatives to coal and coke should be found not only in the power sector but also in the industrial sectors (like steel, silicon and manganese production) in which coal and coke are used as a reductant and for steel production also as a fuel. To this aim many research works have been focused on the development of a coke substitute based on woody biomass and known as “biocarbon”. There are still barriers to overcome, among them: the biocarbon low density, poor mechanical strength and high reactivity. In this paper a new biocarbon production methodology is proposed, based on: pyrolysis at 600 °C, densification (using py…

020209 energyBiocarbon; Compressive strength; Durability; Pine wood chips; Pyrolysis; Pyrolysis oilBiomassCompressive strengthPine wood chips02 engineering and technologyManagement Monitoring Policy and LawDurabilitychemistry.chemical_compound020401 chemical engineeringPyrolysis oilPellet0202 electrical engineering electronic engineering information engineeringCoalResponse surface methodology0204 chemical engineeringbusiness.industryMechanical EngineeringBuilding and ConstructionCokePelletizingPulp and paper industryBiocarbonPyrolysis oilVDP::Teknologi: 500General EnergychemistryEnvironmental sciencebusinessPyrolysisPyrolysisApplied Energy
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A Pareto optimal design approach for simultaneous control of thinning and springback in stamping processes

2009

One of the most relevant research issues in automotive field is focused on the reduction of stamped parts weight also increasing their strength. In this way, a strong research effort is developed on high strength steels which are widely utilized and they require a proper springback control. Springback reduction in sheet metal forming is a typical goal to be pursued which is conflicting with thinning reduction for instance. Thus, such problems can be considered as multi-objective ones characterized by conflicting objectives. What is more, nowadays, a great interest would be focused on the availability of a cluster of possible optimal solutions instead of a single one, particularly in an indu…

0209 industrial biotechnologyEngineeringMathematical optimizationsheet metal stampingAutomotive industryComputational intelligence02 engineering and technologyresponse surface methodBlankMulti-objective optimization[SPI.MAT]Engineering Sciences [physics]/Materialsspringback020901 industrial engineering & automationGeneral Materials ScienceResponse surface methodologySettore ING-IND/16 - Tecnologie E Sistemi Di Lavorazionebusiness.industrythinningStructural engineering[SPI.MECA]Engineering Sciences [physics]/Mechanics [physics.med-ph]Stamping021001 nanoscience & nanotechnologymulti-objective optimizationvisual_artvisual_art.visual_art_medium0210 nano-technologybusinessSheet metalReduction (mathematics)International Journal of Material Forming
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Optimization of antioxidants extraction from peanut skin to prevent oxidative processes during soybean oil storage

2017

8 páginas, 3 figuras, 2 tablas

0301 basic medicineEthanol solventAntioxidantfood.ingredientmedicine.medical_treatmentSoybean oilSoybean oil03 medical and health scienceschemistry.chemical_compound0404 agricultural biotechnologyfoodLipid oxidationmedicineButylated hydroxytolueneOrganic chemistryPeroxide valueFood scienceResponse surface methodology030109 nutrition & dieteticsIn vitro antioxidant methodsExtraction (chemistry)food and beveragesPolyphenols04 agricultural and veterinary sciences040401 food sciencechemistryPolyphenolPrimary and secondary oxidationFood Science
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Optimization of Bacillus cereus Fermentation Process for Selenium Enrichment as Organic Selenium Source

2020

Selenium is an essential trace element and micronutrient for human health. Application of organic selenium in plants and microorganisms as trace element supplement is attracting more and more attention. In this study, Bacillus cereus, an important probiotic, was used for selenium enrichment with sodium selenite as selenium source. The growth curve of B. cereus was investigated, and 150 μg/ml was selected as the concentration of selenium for B. cereus fermentation. With application of response surface methodology, the optimal fermentation conditions were obtained as follows: inoculation quantity of 7%, culture temperature of 33°C, and shaking speed of 170 rpm, leading to the maximal selenium…

0301 basic medicineinorganic chemicalsEndocrinology Diabetes and MetabolismMicroorganismBacillus cereusselenium enrichmentchemistry.chemical_element030209 endocrinology & metabolismlcsh:TX341-641response surface methodology03 medical and health sciences0302 clinical medicineBacillus cereusFood sciencefermentationchemistry.chemical_classification030109 nutrition & dieteticsNutrition and DieteticsbiologyTrace elementfood and beveragesMicronutrientbiology.organism_classificationorganic seleniumchemistryCereusFermentationSelenoproteinlcsh:Nutrition. Foods and food supplySeleniumFood ScienceFrontiers in Nutrition
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Negative-pressure cavitation extraction of cajaninstilbene acid and pinostrobin from pigeon pea [Cajanus cajan (L.) Millsp.] leaves and evaluation of…

2011

Abstract In this study, an efficient negative-pressure cavitation extraction (NPCE) technique was developed to extract cajaninstilbene acid (CSA) and pinostrobin (PI) from pigeon pea [Cajanus cajan (L.) Millsp.] leaves. The operating parameters were optimised using single-factor experiment and central composite design combined with response surface methodology. Well-fitting models for the extraction of CSA and PI were successfully established. From the economic perspective, the selected operating parameters were: extraction pressure −0.075 MPa, extraction temperature 45 °C, material size 40 mesh, ethanol concentration 80%, extraction time 30 min, liquid/solid ratio 30:1 and 4 extraction cyc…

AntioxidantChromatographyABTSCentral composite designbiologyChemistryDPPHmedicine.medical_treatmentExtraction (chemistry)General Medicinebiology.organism_classificationAnalytical ChemistryCajanuschemistry.chemical_compoundBotanymedicineResponse surface methodologyLegumeFood ScienceFood Chemistry
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Stevia rebaudiana Bertoni as a natural antioxidant/antimicrobial for high pressure processed fruit extract: Processing parameter optimization

2013

Response surface methodology was used to evaluate the optimal high pressure processing treatment (300-500 MPa, 5-15 min) combined with Stevia rebaudiana (Stevia) addition (0-2.5% (w/v)) to guarantee food safety while maintaining maximum retention of nutritional properties. A fruit extract matrix was selected and Listeria monocytogenes inactivation was followed from the food safety point of view while polyphenoloxidase (PPO) and peroxidase (POD) activities, total phenolic content (TPC) and antioxidant capacity (TEAC and ORAC) were studied from the food quality point of view. A combination of treatments achieved higher levels of inactivation of L. monocytogenes and of the oxidative enzymes, s…

Antioxidantmedicine.medical_treatmentAntioxidantsAnalytical ChemistryPascalizationFood PreservationOxidative enzymeBotanymedicineSteviaFood scienceResponse surface methodologyPeroxidasePlant ProteinsMangiferabiologyCaricaPlant ExtractsChemistryGeneral Medicinebiology.organism_classificationListeria monocytogenesSteviaAnti-Bacterial AgentsStevia rebaudianaPoint of deliveryFruitFood PreservativesFood qualityCatechol OxidaseCitrus sinensisFood ScienceFood Chemistry
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Solvent-free microwave-assisted extraction of polyphenols from olive tree leaves: Antioxidant and antimicrobial properties

2017

International audience; Response surface methodology (RSM) and artificial neural networks (ANN) were evaluated and compared in order to decide which method was the most appropriate to predict and optimize total phenolic content (TPC) and oleuropein yields in olive tree leaf (Olea europaea) extracts, obtained after solvent-free microwave- assisted extraction (SFMAE). The SFMAE processing conditions were: microwave irradiation power 250-350 W, extraction time 2-3 min, and the amount of sample 5-10 g. Furthermore, the antioxidant and antimicrobial activities of the olive leaf extracts, obtained under optimal extraction conditions, were assessed by several in vitro assays. ANN had better predic…

Antioxidantmedicine.medical_treatment[SDV]Life Sciences [q-bio]Pharmaceutical ScienceAntioxidantsAnalytical Chemistrychemistry.chemical_compoundDrug Discovery[SDV.IDA]Life Sciences [q-bio]/Food engineeringAntimicrobial; Antioxidant; Oleuropein; Olive leaves; Optimization; Solvent-free microwave extraction; Organic ChemistryOlive leavesMicrowaves04 agricultural and veterinary sciences040401 food scienceAnti-Bacterial AgentsChemistry (miscellaneous)Molecular MedicineAntioxidantAntibacterial activityOptimizationStaphylococcus aureusMicrobial Sensitivity TestsArticlelcsh:QD241-4410404 agricultural biotechnologyOlive leaflcsh:Organic chemistryOleuropeinOleaStaphylococcus epidermidismedicine[SPI.GPROC]Engineering Sciences [physics]/Chemical and Process EngineeringResponse surface methodologyPhysical and Theoretical ChemistryOleuropeinolive leaves; solvent-free microwave extraction; oleuropein; antioxidant; antimicrobial; optimizationChromatographyPlant ExtractsExtraction (chemistry)Organic ChemistryPolyphenolsolive leaves;solvent-free microwave extraction;oleuropein;antioxidant;antimicrobial;optimizationPlant LeaveschemistryPolyphenolYield (chemistry)Solvent-free microwave extractionSolventsAntimicrobialNeural Networks Computer
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Hybrid prediction-optimization approaches for maximizing parts density in SLM of Ti6Al4V titanium alloy

2022

AbstractIt is well known that the processing parameters of selective laser melting (SLM) highly influence mechanical and physical properties of the manufactured parts. Also, the energy density is insufficient to detect the process window for producing full dense components. In fact, parts produced with the same energy density but different combinations of parameters may present different properties even under the microstructural viewpoint. In this context, the need to assess the influence of the process parameters and to select the best parameters set able to optimize the final properties of SLM parts has been capturing the attention of both academics and practitioners. In this paper differ…

Artificial neural networkOptimizationResponse surface methodologyArtificial IntelligencePredictive modelMetaheuristic algorithmsIndustrial and Manufacturing EngineeringSoftware
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