Search results for "Rhodium"

showing 10 items of 244 documents

Amino-phosphanes in Rh(I)-catalyzed hydroformylation: new mechanistic insights using D2O as deuterium-labeling agent

2005

International audience; In previous work, we have demonstrated that the dangling amino group in amino-phosphane ligands increases the rate of Rh-catalyzed styrene hydroformylation as a function of the amino group basicity and of the distance between the P and N functions. We now report additional stereochemical and mechanistic insights resulting from new catalytic experiments performed with Rh-α-P,N catalytic systems in the presence of D2O. In addition to the expected D0 product, the formation of the β-D1 aldehyde, PhCH(CH2D)CHO was observed in all cases by 1H and 13C NMR spectroscopy, indicating that H/D exchange occurs for the rhodium-hydride complex. Minor amounts of a β-D2 product, PhCH…

Amino-phosphane ligandsStereochemistryEnantioselectivity010402 general chemistry01 natural sciencesAldehydeInorganic Chemistry[ CHIM.CATA ] Chemical Sciences/CatalysisDeprotonationMoietyRhodium[CHIM.COOR]Chemical Sciences/Coordination chemistryComputingMilieux_MISCELLANEOUSchemistry.chemical_classification010405 organic chemistryLigand[CHIM.ORGA]Chemical Sciences/Organic chemistryHydroformylation catalysis[ CHIM.COOR ] Chemical Sciences/Coordination chemistry[CHIM.CATA]Chemical Sciences/CatalysisAsymmetric induction0104 chemical sciencesEnantiopure drugchemistryH/D isotopic exchangeProtonolysisHydroformylation
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New chiral α-aminophosphine oxides and sulfides: an unprecedented rhodium-catalyzed ligand epimerization

2001

International audience; New chiral α-aminophosphine oxide N,P(O) and sulfide N,P(S) ligands have been prepared in one-pot syntheses by addition of Ph2PH to (S)-PhCH[double bond, length half m-dash]NCH(Ph)CH3, followed by oxidation with O2 or S8. Crystallization from cold methanol leads to the isolation of an enantiomerically pure single N,P(O) diastereomer and to a 1 : 1 mixture of the two N,P(S) diastereomers. The coordination chemistry of these ligands with [RhCl(COD)]2 and [RhCl(CO)2]2 has been investigated under argon and syngas. At high temperatures, a P–C oxidative addition of the N,P(O) ligand followed by imine elimination leads to several hydrido rhodium species. The complexes conta…

AminophosphinesIminechemistry.chemical_element010402 general chemistry01 natural sciencesMedicinal chemistryCatalysisCoordination complexRhodiumCatalysischemistry.chemical_compoundEpimerizationMaterials ChemistryOrganic chemistryRhodium[CHIM.COOR]Chemical Sciences/Coordination chemistrychemistry.chemical_classification010405 organic chemistryLigandPhosphine oxides and sulfidesDiastereomerGeneral ChemistryOxidative addition0104 chemical scienceschemistryHydroformylationHydroformylation
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1,2‐Benzothiazine Derivatives from Sulfonimidamides by Metal‐Catalyzed Annulation Reactions in Solution and under Solvent‐Free Mechanochemical Condit…

2021

Advanced synthesis & catalysis (2021). doi:10.1002/adsc.202001505 special issue: "Hot Topic: C-H Activation"

Annulationkemiallinen synteesiSolvent free660iridium catalysisChemistrysulfonimidamideGeneral ChemistryBenzothiazine12-benzothiazineC−H activationCatalysisMetalchemistry.chemical_compoundMechanochemistryvisual_artkatalyysirikkiyhdisteetddc:660visual_art.visual_art_mediumrhodium catalysisOrganic chemistrymechanochemistryorgaaniset yhdisteet
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First total synthesis of antiostatin A1, a potent carbazole-based naturally occurring antioxidant.

2009

The first total synthesis of the potent antioxidant antiostatin A1 is reported, where its key features rely on a chemo- and regioselective rhodium-catalysed crossed alkyne cyclotrimerisation reaction applying functionalised ynamides and a palladium-catalysed arylamidation reaction.

Antioxidantmedicine.medical_treatmentCarbazolesAlkyneAntioxidantsCatalysischemistry.chemical_compoundAntiostatin A1Materials ChemistrymedicineOrganic chemistryRhodiumchemistry.chemical_classificationMolecular StructureCarbazoleMetals and AlloysTotal synthesisRegioselectivityStereoisomerismGeneral ChemistryKey featuresSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialschemistryCyclizationCeramics and CompositesPalladiumChemical communications (Cambridge, England)
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The selective synthesis of metallanucleosides and metallanucleotides: a new tool for the functionalization of nucleic acids.

2012

Nucleobases team up: the efficient and selective preparation of purine-derived metallanucleosides, metallanucleotides, and metalladinucleotides having M-C bonds (M=Ir(III), Rh(III)) is reported for the first time. The results presented may be applied to the synthesis of functionalized nucleic acids, or DNA/RNA-modified segments.

Base pairMetalationchemistry.chemical_elementIridiumCatalysisNucleobaseRhodiumchemistry.chemical_compoundNucleic AcidsOrganic chemistryRhodiumBase PairingPurine NucleotidesBase SequenceChemistryOrganic ChemistryRNAGeneral ChemistryDNAPurine NucleosidesCombinatorial chemistryMetalsNucleic acidSurface modificationRNADNAChemistry (Weinheim an der Bergstrasse, Germany)
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Rhodium(III)-catalyzed ring-opening of strained olefins through C–H activation of O-acetyl ketoximes: an efficient synthesis of trans-functionalized …

2013

An efficient strategy for the stereoselective synthesis of functionalized cyclopentenes and spiro[2.4]heptenes from strained olefins via C–H activation of aryl ketone O-acetyl ketoximes using [RhCl2Cp∗]2 catalyst is described. The results revealed that a wide range of readily accessible aryl and heteroaryl ketoximes are compatible in this method for the ring opening of bicyclic and spirotricyclic olefins.

Bicyclic moleculeChemistryArylOrganic Chemistrychemistry.chemical_elementAryl ketoneRing (chemistry)BiochemistryMedicinal chemistryRhodiumCatalysischemistry.chemical_compoundDrug DiscoveryCyclopenteneStereoselectivityta116Tetrahedron Letters
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ChemInform Abstract: An Easy Access to Fused Chromanones via Rhodium Catalyzed Oxidative Coupling of Salicylaldehydes with Heterobicyclic Olefins.

2016

Diazabicyclic and urea-derived bicyclic olefins react with salicylaldehydes to produce various types of fused chromanone systems of biological interest in a single step (mechanism).

Bicyclic moleculeChemistrychemistry.chemical_elementOxidative coupling of methaneSingle stepGeneral MedicineCombinatorial chemistryCatalysisRhodiumChemInform
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Synthesis and coordinating ability of an anionic cobaltabisdicarbollide ligand geometrically analogous to BINAP.

2004

The anionic chelating ligand [1,1'-(PPh 2 ) 2 -3,3'-Co(1,2-C 2 B 9 H 1 0 ) 2 ] - has been synthesized from [3,3'-Co(1,2-C 2 B 4 H 1 1 ) 2 ] - in very good yield in a one-pot process with an easy work-up procedure. The coordinating ability of this ligand has been studied with Group 11 metal ions (Ag, Au) and with transition-metal ions (Pd, Rh). The two dicarbollide halves of the [1,1'-(PPh 2 ) 2 -3,3'-Co(1,2-C 2 B 9 H 1 0 ) 2 ] - ligand can swing about one axis in a manner analogous to the constituent parts of BINAP and ferrocenyl phosphine derivatives. All these ligands function as hinges, with the most important property in relation to the coordination requirements of the metal being the P…

Boron CompoundsModels MolecularMagnetic Resonance SpectroscopySilverStereochemistryMetal ions in aqueous solutionMolecular ConformationHomogeneous catalysisBoranesNaphthalenes010402 general chemistryCrystallography X-Ray01 natural sciencesCatalysischemistry.chemical_compoundOrganometallic CompoundsChelationRhodiumBINAPChelating AgentsAtropisomerMolecular Structure010405 organic chemistryChemistryLigandOrganic ChemistryGeneral ChemistryCations Monovalent0104 chemical sciencesCrystallographySpectrometry Mass Matrix-Assisted Laser Desorption-IonizationGoldPhosphinePalladiumChemistry (Weinheim an der Bergstrasse, Germany)
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Rhodium (II) compounds with functionalized metalated phosphines as bridging ligands

2005

Abstract The reaction of Rh2(O2CCH3)4 · 2CH3OH with the phosphine P(4-BrC6H4)2(C6H5), 2, results in the formation of the monometalated compound Rh2(O2CCH3)3[PC] · 2CH3CO2H (PC representing a metalated P(4-BrC6H4)2(C6H5)). The reaction involves selective metalation of the phosphine at one Br-substituted ring (12:1 isomer ratio). The reaction of Rh2(O2CCH3)3[(4-BrC6H3)P(4-BrC6H4)(C6H5)] · 2CH3CO2H, 4, with one additional mol of triphenylphosphine yields a mixture of two main stereoisomers Rh2(O2CCH3)2[(4-BrC6H3)P(4-BrC6H4)(C6H5)] [(C6H4)P(C6H5)2] · 2CH3CO2H, 5a and 5b, that were isolated as pure compounds. These two compounds were resolved in the corresponding M and P enantiomers as trifluoro…

Catalytic transformationMetalationStereochemistryOrganic Chemistrychemistry.chemical_elementBiochemistryCatalysisRhodiumInorganic Chemistrychemistry.chemical_compoundchemistryMaterials ChemistryPhysical and Theoretical ChemistryEnantiomerTriphenylphosphinePhosphineJournal of Organometallic Chemistry
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Heterogeneous Dinuclear Rhodium(II) Hydroformylation Catalysts—Performance Evaluation and Silsesquioxane-Based Chemical Modeling

2001

Supported, air stable, and reusable hydroformylation catalysts have been prepared by immobilizing dinuclear rhodium(II) complexes bearing ortho-metalated arylphosphane ligands on amorphous silica and mesoporous MCM-41 supports by phosphane tethers. The oligosilsesquioxane model complex of the catalytic site 1 has been prepared analogously and characterized by single-crystal X-ray diffraction analysis.

ChemistryChemical process modelingchemistry.chemical_elementGeneral ChemistryGeneral MedicineHeterogeneous catalysisCatalysisSilsesquioxaneRhodiumCatalysischemistry.chemical_compoundPolymer chemistryOrganic chemistryAmorphous silicaMesoporous materialHydroformylationAngewandte Chemie
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