Search results for "Role"
showing 10 items of 1994 documents
Identifying Coping Profiles and Profile Differences in Role Engagement and Subjective Well-Being
2014
Coping strategies are not necessarily mutually exclusive and can be used simultaneously, a fact which has rarely been examined in coping research. We examined what kinds of coping profiles could be found in data concerning Finnish health care and service employees (n = 2756). We also studied whether role engagement (family-to-work-enrichment, work-to-family-enrichment, emotional energy at work, and work engagement) and subjective well-being (life, parental, and marital satisfaction, and psychological distress) differ between coping profiles. The data were analyzed through latent profile (LPA) and covariance analyses (Ancovas). LPA revealed seven distinct coping profiles: two active groups,…
Coping and parental role competence of mothers of preterm infant
2014
The study was aimed at obtaining knowledge about mothers' experiences of preterm birth. The objective of the study is to explore coping strategies and self- perceived parental competence, in mothers of infant born moderately and severely preterm and admitted to the Neonatal Intensive Care Unit (NICU). METHODS: The study involved a group of 16 mothers of moderately preterm children (weeks' gestational age: mean=34, SD=2 and birth weight: mean=2000 g, SD=200 g) and a group of 14 mothers of severely preterm children (weeks' gestational age: mean=29, SD=2 and birth weight: mean=1700 g, SD=350 g). The following instruments were used with mothers to investigate focus areas of research: Coping Ori…
Bioactive pyrrole-based compounds with target selectivity
2020
The discovery of novel synthetic compounds with drug-like properties is an ongoing challenge in medicinal chemistry. Natural products have inspired the synthesis of compounds for pharmaceutical application, most of which are based on N-heterocyclic motifs. Among these, the pyrrole ring is one of the most explored heterocycles in drug discovery programs for several therapeutic areas, confirmed by the high number of pyrrole-based drugs reaching the market. In the present review, we focused on pyrrole and its hetero-fused derivatives with anticancer, antimicrobial, and antiviral activities, reported in the literature between 2015 and 2019, for which a specific target was identified, being resp…
The Impact of the Mass Spectrum of Lenses in Quasar Microlensing Studies. Constraints on a Mixed Population of Primordial Black Holes and Stars
2020
We show that quasar microlensing magnification statistics induced by a population of point microlenses distributed according to a mass-spectrum can be very well approximated by that of a single-mass, "monochromatic", population. When the spatial resolution (physically defined by the source size) is small as compared with the Einstein radius, the mass of the monochromatic population matches the geometric mean of the mass-spectrum. Otherwise, the best-fit mass can be larger. Taking into account the degeneracy with the geometric mean, the interpretation of quasar microlensing observations under the hypothesis of a mixed population of primordial black holes and stars, makes the existence of a s…
Can QCD Axion Stars explain Subaru HSC microlensing?
2021
A non-negligible fraction of the QCD axion dark matter may form gravitationally bound Bose Einstein condensates, which are commonly known as axion stars or axion clumps. Such astrophysical objects have been recently proposed as the cause for the single candidate event reported by Subaru Hyper Suprime-Cam (HSC) microlensing search in the Andromeda galaxy. Depending on the breaking scale of the Peccei-Quinn symmetry and the details of the dark matter scenario, QCD axion clumps may form via gravitational condensation during radiation domination, in the dense core of axion miniclusters, or within axion minihalos around primordial black holes. We analyze all these scenarios and conclude that the…
A brief review on primordial black holes as dark matter
2021
Primordial black holes (PBHs) represent a natural candidate for one of the components of the dark matter (DM) in the Universe. In this review, we shall discuss the basics of their formation, abundance and signatures. Some of their characteristic signals are examined, such as the emission of particles due to Hawking evaporation and the accretion of the surrounding matter, effects which could leave an impact in the evolution of the Universe and the formation of structures. The most relevant probes capable of constraining their masses and population are discussed.
Limits on the Mass and Abundance of Primordial Black Holes from Quasar Gravitational Microlensing
2017
The idea that dark matter can be made of intermediate-mass primordial black holes in the $10M_\odot \lesssim M \lesssim 200M_\odot$ range has recently been reconsidered, particularly in the light of the detection of gravitational waves by the LIGO experiment. The existence of even a small fraction of dark matter in black holes should nevertheless result in noticeable quasar gravitational microlensing. Quasar microlensing is sensitive to any type of compact objects in the lens galaxy, to their abundance, and to their mass. We have analyzed optical and X-ray microlensing data from 24 gravitationally lensed quasars to estimate the abundance of compact objects in a very wide range of masses. We…
Familial hypercholesterolæmia in children and adolescents: Gaining decades of life by optimizing detection and treatment
2015
Contains fulltext : 155263.pdf (Publisher’s version ) (Open Access) Familial hypercholesterolaemia (FH) is a common genetic cause of premature coronary heart disease (CHD). Globally, one baby is born with FH every minute. If diagnosed and treated early in childhood, individuals with FH can have normal life expectancy. This consensus paper aims to improve awareness of the need for early detection and management of FH children. Familial hypercholesterolaemia is diagnosed either on phenotypic criteria, i.e. an elevated low-density lipoprotein cholesterol (LDL-C) level plus a family history of elevated LDL-C, premature coronary artery disease and/or genetic diagnosis, or positive genetic testin…
Nurse‐led counseling for coronary artery disease patients: A 1‐year follow‐up study
2021
Nurse-led counseling and systematic follow-up has been shown to reduce cardiovascular risk factor levels. The study aim was to investigate if cardiovascular risk factor levels could be reduced in patients with coronary artery disease with a nurse-led intervention and to report patients’ evaluations of nurse-led counseling. The study design was a real-life longitudinal follow-up counseling intervention. Data were collected from November 2017 to May 2020. The nurse-led intervention and patients’ follow-up time was one year. Of the 78 patients recruited, 74 completed the study. The most significant findings were in the levels of total cholesterol, low-density lipoprotein cholesterol and trigly…
ChemInform Abstract: Switchable Palladium-Catalyst Reaction of Bromomethyl Sulfoxides, CO, and N-Nucleophiles: Aminocarbonylation at Csp3versus Oxida…
2013
Pd2(dba)3/ Xantphos-catalyzed coupling of the sulfoxides (I) and (V) with amines and carbon monoxide allows a new and efficient access to amides of type (IV) and (VI).