Search results for "SAF"

showing 10 items of 2183 documents

Correlates of physical activity among community-dwelling individuals aged 65 years or older with anxiety in six low- and middle-income countries.

2018

ABSTRACTBackground:Given the important health benefits of physical activity (PA) and the higher risk for physical inactivity in people with anxiety, and the high prevalence of anxiety and low PA among the elderly, there is a need for research to investigate what factors influence PA participation among anxious older individuals. We investigated PA correlates among community-dwelling adults aged ≥ 65 years with anxiety symptoms in six low- and middle-income countries.Methods:Cross-sectional data from the World Health Organization's Study on Global Ageing and Adult Health were analyzed. PA level was assessed by the Global Physical Activity Questionnaire. 980 participants with anxiety (mean ag…

MaleGerontologymedicine.medical_specialtyCross-sectional studyHealth Behaviorphysical activityPoison controlAnxiety*anxietySuicide preventionOccupational safety and health03 medical and health sciences0302 clinical medicineInjury prevention*physical activityPrevalencemedicineHumans030212 general & internal medicineDeveloping CountriesExerciseAgedAged 80 and overanxiety; exercise; physical activityPublic health*exerciseHealth SurveysMental health030227 psychiatryPsychiatry and Mental healthClinical PsychologyCross-Sectional StudiesLogistic ModelsMental HealthMultivariate Analysisanxiety physical activity exerciseAnxietyFemaleGeriatrics and Gerontologymedicine.symptomPsychologyGerontology
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Health condition and physical function as predictors of adherence in long-term strength and balance training among community-dwelling older adults

2015

AIM: Strength and balance training (SBT) has remarkable health benefits, but little is known regarding exercise adherence in older adults. We examined the adherence to strength and balance training and determinants of adherence among ≥75 year old adults. METHODS: 182 community-dwelling individuals (aged 75-98 years, 71% female) began group-based SBT as part of a population-based Geriatric Multidisciplinary Strategy for the Good Care of the Elderly study. Training was offered once a week for 2.3 years. Adherence was defined as the proportion of attended sessions relative to offered sessions. Participants were classified based on their adherence level into low (≤33.3%), moderate (33.4-66.5%) …

MaleGerontologymedicine.medical_specialtyHealth (social science)Activities of daily livinggeriatric assessmentFrail ElderlyHealth StatusMovementPopulationPsychological interventionPoison controlWalkingOccupational safety and healthphysical functionResidence CharacteristicsActivities of Daily LivingInjury preventionmedicineHumansexcerciseeducationExercisePostural BalancePhysical Therapy ModalitiesAgedAged 80 and overeducation.field_of_studybusiness.industryagingResistance Trainingta3141mobilityPreferred walking speedSocioeconomic FactorsBerg Balance ScalePhysical therapyPatient ComplianceFemaleGeriatrics and GerontologybusinessGerontologyArchives of Gerontology and Geriatrics
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Mortality and health-related habits in 900 Finnish former elite athletes and their brothers.

2018

BackgroundThere is conflicting evidence on the associations between participation in vigorous sports, health habits, familial factors and subsequent mortality. We investigated all-cause mortality and health-related behaviour among former elite athletes and their brothers.MethodsThe mortality of Finnish male former elite athletes, who had represented Finland between 1920 and 1965 (n=900) and their age-matched brothers (n=900), was followed from the time when athlete started an elite athlete career until 31 December 2015. The age-adjusted HRs were calculated by a paired Cox proportional hazards model. In 2001, surviving participants (n=199 athletes and n=199 age-matched brothers) reported the…

MaleHealth BehaviorPoison controlADULTHOODmortality rate030204 cardiovascular system & hematologySuicide preventionOccupational safety and healthveljetCohort Studies0302 clinical medicinebrothersSurveys and QuestionnairesSELF-RATED HEALTHMedicineOrthopedics and Sports MedicinekohorttitutkimusFinlandSelf-rated healthALL-CAUSE MORTALITYAged 80 and overbiologySmokingTWIN COHORTGeneral Medicine3142 Public health care science environmental and occupational healthCohortCARDIORESPIRATORY FITNESSCohort studyhuippu-urheilijatkuolleisuusAdultmedicine.medical_specialtyelintavatAlcohol DrinkingDISEASE-SPECIFIC MORTALITYPhysical Therapy Sports Therapy and Rehabilitation03 medical and health sciencesYoung AdultInjury preventioncohort studyHumansMortalityCARDIOVASCULAR EVENTSExerciselifestyle habitsAgedProportional Hazards Modelstop athletesbusiness.industryAthletesSiblings030229 sport sciencesbiology.organism_classificationPHYSICAL-ACTIVITYAthletesPhysical therapyRISK-FACTORSbusinessFOLLOW-UPDemographyBritish journal of sports medicine
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Behavioral Health at School: Do Three Competences in Road Safety Education Impact the Protective Road Behaviors of Spanish Children?

2019

Background: Education in road safety (also known as Road Safety Education&mdash

MaleHealth Toxicology and MutagenesisApplied psychologyPsychological interventionPoison controllcsh:MedicineSuicide preventionOccupational safety and healthArticlebehavioral healthtraffic crashes03 medical and health sciencesHabits0302 clinical medicineprotective road behaviorschildren0502 economics and businessInjury preventionHumans030212 general & internal medicineChildSocial Behavior050210 logistics & transportationInfants PsicologiaSchoolseducation in road safety05 social sciencesPerspective (graphical)Conducta (Psicologia)lcsh:RPublic Health Environmental and Occupational HealthAccidents TrafficHuman factors and ergonomicsRisk perceptionCross-Sectional StudiesPsicologiaSpainFemaleSafetyPsychologyroad safetyhuman activitiesrseInternational Journal of Environmental Research and Public Health
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Determination of propofol by GC/MS and fast GC/MS-TOF in two cases of poisoning

2017

Two cases of suspected acute and lethal intoxication caused by propofol were delivered by the judicial authority to the Department of Sciences for Health Promotion and Mother-Child Care in Palermo, Sicily. In the first case a female nurse was found in a hotel room, where she lived with her mother; four 10 mg/mL vials and two 20 mg/mL vials of propofol were found near the decedent along with syringes and needles. In the second case a male nurse was found in the operating room of a hospital, along with a used syringe. In both cases a preliminary systematic and toxicological analysis indicated the presence of propofol in the blood and urine. As a result, a method for the quantitative determina…

MaleHealth Toxicology and MutagenesisHypnotics and SedativeUrineToxicology01 natural sciencesVialGas Chromatography-Mass SpectrometryAnalytical Chemistry03 medical and health sciencesForensic Toxicology0302 clinical medicineSettore MED/43 - Medicina LegaleEnvironmental ChemistryMedicineHumansHypnotics and SedativesSettore CHIM/01 - Chimica Analitica030216 legal & forensic medicinePropofolSyringeChemical Health and Safetybusiness.industry010401 analytical chemistryForensic toxicologyQuantitative determination0104 chemical sciencesManner of deathSuicideAnesthesiaFemaleGas chromatography–mass spectrometryDrug OverdosebusinessPropofolHomicidemedicine.drugHuman
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A Simple Microassay for the Determination of Hydrazine in Biological Samples. Effect of Hydrazine and Isoniazid on Liver and Brain Glutathione

1987

A simple microassay for the determination of hydrazine in laboratory samples is presented. The colored product of the reaction of p-dimethylaminobenzaldehyde with hydrazine was tested at 470 nm using double-beam mode in different samples. Internal standards and data on blood serum, liver, and brain of rats treated with hydrazine or isoniazid are presented. The tissue glutathione content of these rats was determined, and the possible implication of glutathione in the brain toxicity of hydrazine is discussed.

MaleHealth Toxicology and MutagenesisMetaboliteToxicologyAnalytical Chemistrychemistry.chemical_compoundBlood serumSpectrophotometryIsoniazidmedicineAnimalsEnvironmental ChemistryHydrazine (antidepressant)Brain ChemistryChemical Health and SafetyChromatographymedicine.diagnostic_testIsoniazidMetabolismGlutathioneGlutathioneRatsHydrazinesLiverchemistryBiochemistryToxicitymedicine.drugJournal of Analytical Toxicology
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Bioaccumulation of persistent organic pollutants in the gonads of Barbus barbus (Linnaeus, 1758)

2020

Maps with grey or even white spaces are still present in spite of the fact that persistent organic pollutants (POPs) are at the forefront of research in aquatic toxicology and environmental safety. This is also the case for the Mureș River basin. The intensive use of industrial substances such as polychlorinated biphenyls (PCBs) and pesticides such as organochlorine compounds (OCPs) has caused global contamination of the aquatic environment. In our study we have found very high concentrations of both PCBs (2110-169,000 ng/g lipid weight ΣPCB, 1950-166,000 ng/g lipid weight ΣPCB7) and OCPs (1130-7830 ng/g lipid weight ΣDDT, 47.6-2790 ng/g lipid weight ΣHCH, 5.53-35.6 ng/g lipid weight ΣChlor…

MaleHealth Toxicology and Mutagenesismedia_common.quotation_subjectCyprinidae0211 other engineering and technologies02 engineering and technology010501 environmental sciences01 natural sciencesAquatic toxicologyRiversEnvironmental safetyHydrocarbons ChlorinatedAnimalsPesticidesGonads0105 earth and related environmental sciencesmedia_commonPollutant021110 strategic defence & security studiesbiologyRomaniaChemistryPublic Health Environmental and Occupational HealthGeneral MedicineContaminationPesticideBarbus barbusbiology.organism_classificationBioaccumulationPolychlorinated BiphenylsPollutionEnvironmental chemistryBioaccumulationFemaleReproductionWater Pollutants ChemicalEnvironmental MonitoringEcotoxicology and Environmental Safety
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A novel haemoprotein induced by isosafrole pretreatment in the rat

1978

Abstract Sodium dodecyl sulphate-polyacrylamide gel electrophoresis has been used to demonstrate that pretreatment of rats with isosafrole results in the formation of a novel species of cytochrome P-450 (mol. wt. 54,000) quite distinct from that induced by phenobarbitone pretreatment (mol. wt. 50,000) or 3-methylcholanthrene (mol. wt. 58,000).

MaleHemeproteinCytochromeSodiumBiophysicschemistry.chemical_elementDioxolesBiochemistrychemistry.chemical_compoundCytochrome P-450 Enzyme SystemIsomerismSafroleMoleAnimalsMolecular BiologyGel electrophoresisChromatographybiologyChemistrySpectrum AnalysisCell BiologyRatsMolecular WeightBiochemistryIsosafroleEnzyme InductionPhenobarbitalMicrosomes Liverbiology.proteinApoproteinsMethylcholanthreneBiochemical and Biophysical Research Communications
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Observational study of chronic myeloid leukemia Italian patients who discontinued tyrosine kinase inhibitors in clinical practice.

2018

It is judged safe to discontinue treatment with tyrosine kinase inhibitors (TKI) for chronic myeloid leukemia (CML) in experimental trials on treatment-free remission (TFR). We collected a total of 293 Italian patients with chronic phase CML who discontinued TKI in deep molecular response. Seventy-two percent of patients were on treatment with imatinib, and 28% with second generation TKI at the time of discontinuation. Median duration of treatment with the last TKI was 77 months [Interquartile Range (IQR) 54;111], median duration of deep molecular response was 46 months (IQR 31;74). Duration of treatment with TKI and duration of deep molecular response were shorter with second generation TK…

MaleImatinib mesylate discontinuation; chronic myelogenous leukemia; treatment-free remission; long-term outcomes; molecular response; cml patients; recommendations; management; dasatinib; cessationchemistry.chemical_compound0302 clinical medicineTreatment Free RemissionPregnancyMED/15 - MALATTIE DEL SANGUEInterquartile rangeingleseMedicinedasatinibChronic Myelogenous Leukemiatreatment-free remissionPonatinibmolecular responseHematologyMiddle AgedProtein-Tyrosine Kinasescml patientsDasatinibTreatment OutcomeLeukemia Myeloid Chronic-PhaseDisease ProgressionImatinib MesylateFemaleChronic Myelogenous Leukemia; Discontinuation; Treatment Free Remissionlong-term outcomesmanagementmedicine.drugAdultmedicine.medical_specialtyChronic Myeloid LeukemiaSocio-culturaleDiscontinuationArticletyrosine kinase inhibitors discontinued treatment chronic myeloid leukemia treatment-free remission (TFR)Safety-Based Drug Withdrawals03 medical and health scienceschronic myeloid leukemia tyrosine kinase inhibitors discontinuationMedian follow-upLeukemia Myelogenous Chronic BCR-ABL PositiveInternal medicineImatinib mesylate discontinuationHumansProtein Kinase InhibitorsRetrospective Studiesbusiness.industryImatinibmedicine.diseaseDiscontinuationrespiratory tract diseasesSettore MED/15 - MALATTIE DEL SANGUEcessationNilotinibchemistryrecommendationsbusiness030215 immunologyChronic myelogenous leukemia
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Isolation of a high spin form of cytochrome P-450 induced in rat liver by 3-methylcholanthrene.

1983

Abstract A form of cytochrome P-450 (P-450 MC1) has been isolated from the livers of 3-methylcholanthrene-treated rats. The molecular weight is 54,500 and the heme iron is in the high spin configuration which clearly differenciates this form from the other major cytochrome induced by 3-methylcholanthrene (P-450 MC2). Whilst MC2 actively dealkylated 7-ethoxycoumarin and 7-ethoxyresorufin, MC1 was only active with 7-ethoxyresorufin. Ouchterlony immunodiffusion analysis and ELISA showed that anti MC1 and anti MC2 reacted with both MC1 and MC2 but preferentially with the homologous antigen. Both anti MC1 and MC2 cross-reacted strongly with microsomes from 3-methylcholanthrene, Aroclor 1254 and …

MaleImmunodiffusionCytochromeBiophysicsEnzyme-Linked Immunosorbent AssayBiochemistrychemistry.chemical_compoundCytochrome P-450 Enzyme SystemmedicineAnimalsInducerMolecular BiologybiologyRats Inbred StrainsCell BiologyOuchterlony double immunodiffusionRatsImmunodiffusionchemistryBiochemistryIsosafroleEnzyme InductionMethylcholanthreneMicrosomebiology.proteinMicrosomes LiverPhenobarbitalmedicine.drugMethylcholanthreneBiochemical and biophysical research communications
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