Search results for "SAGE"

showing 10 items of 1373 documents

A potential solution to avoid overdose of mixed drugs in the event of Covid-19: Nanomedicine at the heart of the Covid-19 pandemic.

2021

Since 2020, the world is facing the first global pandemic of 21st century. Among all the solutions proposed to treat this new strain of coronavirus, named SARS-CoV-2, the vaccine seems a promising way but the delays are too long to be implemented quickly. In the emergency, a dual therapy has shown its effectiveness but has also provoked a set of debates around the dangerousness of a particular molecule, hydroxychloroquine. In particular, the doses to be delivered, according to the studies, were well beyond the acceptable doses to support the treatment without side effects. We propose here to use all the advantages of nanovectorization to address this question of concentration. Using quantum…

Protein Conformation alpha-HelicalComputer science02 engineering and technologyAzithromycinDrug Delivery SystemsPandemicMaterials ChemistryDrug Dosage CalculationsSpectroscopymedia_common0303 health sciencesEvent (computing)021001 nanoscience & nanotechnologyComputer Graphics and Computer-Aided DesignMolecular Docking SimulationNanomedicineRisk analysis (engineering)Spike Glycoprotein CoronavirusDensity functional theory calculationsNanomedicineThermodynamicsNitrogen OxidesAngiotensin-Converting Enzyme 20210 nano-technologyHydroxychloroquineProtein BindingDrugBoron CompoundsCoronavirus disease 2019 (COVID-19)media_common.quotation_subjectSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Molecular Dynamics SimulationAntiviral AgentsArticle03 medical and health sciencesHumansProtein Interaction Domains and MotifsDual therapyPhysical and Theoretical Chemistry030304 developmental biologyDrug transportBinding SitesSARS-CoV-2Molecular dynamics simulationsCOVID-19NanostructuresCOVID-19 Drug TreatmentKineticsQuantum TheoryProtein Conformation beta-StrandNanovectorizationJournal of molecular graphicsmodelling
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Les prédicteurs en grande section maternelle de la réussite en lecture en fin de première année de l'école primaire : l'impact du nom des lettres

2009

A number of variables predicting the success or failure in learning to read has been presented in the literature. Investigations, however, aiming to evaluate the impact of these factors in multivariate models are rare, particularly in French, and do not take into account participants' individual and social characteristics. In this perspective, a longitudinal study, comprising 199 students, was realised from kindergarten through first grade. The results show that, among all the variables studied, the naming of consonants and vowels in kindergartens is the best predictor of ackowledging both decoding letters and written comprehension at the end of the first grade. A discussion furthers the im…

PrédicteurApprentissage de la lecture[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/Education[ SHS.LANGUE ] Humanities and Social Sciences/Linguistics[ SCCO.LING ] Cognitive science/Linguistics[SHS.LANGUE]Humanities and Social Sciences/Linguistics[SCCO.LING]Cognitive science/LinguisticsRéussite[SCCO.LING] Cognitive science/LinguisticsMaternelle grande section[SHS.LANGUE] Humanities and Social Sciences/Linguisticslinguistique
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Les automatismes cognitifs

1995

International audience

Psychology of LearningCognitionpsychologie cognitiveCognitive psychology[SHS] Humanities and Social Sciencespsychologie de l'apprentissageComputingMilieux_MISCELLANEOUS[SHS]Humanities and Social Sciences
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Potentiel de l’éco-acoustique pour l’étude des rythmes et paysages d’un socio-écosystème de montagne : le cas exploratoire de la vallée du Vicdessos

2022

Pyrénées[SHS.ARCHI]Humanities and Social Sciences/Architecture space management[SDE.MCG]Environmental Sciences/Global Changes[SHS.GEO] Humanities and Social Sciences/Geographybio-acoustiqueéco-acoustiquePyrénées ariégeoises[SHS.GEO]Humanities and Social Sciences/Geographysocio-écosystème[SDE.ES]Environmental Sciences/Environmental and Societypaysages sonoresOHM[SDE.BE] Environmental Sciences/Biodiversity and Ecology[SDE.MCG] Environmental Sciences/Global ChangesVicdessos[SHS.ENVIR] Humanities and Social Sciences/Environmental studies[SHS.ENVIR]Humanities and Social Sciences/Environmental studiesHaut Vicdessosacoustique[SDE.ES] Environmental Sciences/Environmental and Society[SDE.BE]Environmental Sciences/Biodiversity and Ecology[SHS.ARCHI] Humanities and Social Sciences/Architecture space managementObservatoire Homme Milieu
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Rapprochements, croisements, axes de recherches à développer, applications pratiques

2016

National audience

Pédagogie universitaire[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationApprentissage scolaire[ SHS.EDU ] Humanities and Social Sciences/EducationRecherche scientifiqueComputingMilieux_MISCELLANEOUSEnseignement supérieur
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Les pratiques pédagogiques des enseignants universitaires :

2012

In France, some studies (Boyer & Coridian, 2002; Clanet, 2001) have highlighted the heterogeneity of teaching practices at the university, especially in the first year, but don't analyze accurately the effects of this variety on the students. However, these practices are not without consequences for them (Bireaud 1990; Bellat Duru, 1995; Galinon Menelec, 1996). So it is to this reflection that is dedicated the research presented in this article. Firstly will be presented studies in France and abroad about the description of practices. The second part will focus on the effects induced by them on students. Finally, we will present an innovative viewpoint of research, on the relationship betwe…

Pédagogie universitaire[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/Educationfreshman year[ SHS.EDU ] Humanities and Social Sciences/Educationteaching practices in universityPratique pédagogiqueways of studyingEnseignement supérieurUniversitémotivationHétérogénéitéEfficacité pédagogiqueMéthode d'apprentissageFranceheterogeneity and efficiency practicesSupérieur premier cycle
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Le numérique à l'école primaire. Analyse des effets conjoints sur les élèves et les enseignants

2020

International audience; Les technologies numériques sont investies en France depuis plusieurs années par les pouvoirs politiques comme un instrument de lutte contre l'échec scolaire. L'hypothèse est parfois faite que les technologies de l'information et de la communication en éducation (TICE) améliorent sensiblement la qualité de l'éducation en modifiant et facilitant les conditions d'apprentissage des élèves. Cependant, les travaux de recherche montrent des effets relativement ambigus de l'utilisation des nouvelles technologies sur les acquis des élèves.

PédagogieTICEffetTechnologie de l'éducationQualité de l'éducation[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationPratique numériqueCondtion d'enseignementEchec scolairePolitique de lutteApprentissage scolaireTICERéussite scolaire
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Pédagogie muséale et enseignement du volcanisme à la Réunion

2003

Research into pedagogy in museums underlines the double tranposition of the theory principles of the science media and of psycho-pedagogy. At stake is understanding why and how pupils can build their scientific learning in a museum environment. This present contribution will propose a reflection on this issue based on the example of the teaching of volcanism on Réunion Island. The analysis of interviews conducted with teachers in first schools and secondary schools shows to what extent the pupils benefit from a significant pedagogical impact in the framework of their visits to the thematic museum in Piton de la Fournaise. The results show that the teachers, going further than the objectives…

Pédagogie[SHS.EDU]Humanities and Social Sciences/EducationPedagogyPsychopedagogy[SHS.EDU] Humanities and Social Sciences/EducationDidactics[ SHS.EDU ] Humanities and Social Sciences/EducationEnseignement des sciencesApprentissage des sciencesScientific learningDidactiqueReunion IslandGeology teachingPsychopédagogieMuseumMuséeIle de la RéunionEffet pédagogique
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LU e-resursu repozitorija izmantošana

2020

Pētniecības rezultātu pieejamība - starptautiskaInstitutional repository - usage:SOCIAL SCIENCES::Other social sciences::European research cooperation [Research Subject Categories]E-resource repository of the University of LatviaOpenAIRE platformaLU e-resursu repozitorijsPētniecības rezultātu pieejamība - Latvijas UniversitāteRepozitorija izmantošanaAtvērtā piekļuve:SOCIAL SCIENCES::Other social sciences::Library and information science [Research Subject Categories]
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High-performance micellar liquid chromatography determination of sulphonamides in pharmaceuticals after azodye precolumn derivatization

1995

Abstract A chromatographic procedure with precolumn derivatization to form the N-(1-naphthyl)ethylenediamine dihydrochloride azodyes is proposed for the analysis of several sulphonamides (sodium sulphacetamide, sulphadiazine, sulphaguanidine, sulphamerazine, sulphamethizole, sulphamethoxazole, sulphanilamide and sulphathiazole) in pharmaceutical preparations (tablets, pills, capsules, suspensions and drops). The separation is performed with a 0.05 M sodium dodecyl sulphate/2.4% pentanol eluent at pH 7. The precolumn derivatization improved the resolution in the chromatograms and increased the selectivity in the determination of mixtures of sulphonamides and in preparations where other drugs…

Quality ControlSulfonamidesChromatographyChemistrySodiumClinical BiochemistryPharmaceutical Sciencechemistry.chemical_elementHydrogen-Ion ConcentrationHigh-performance liquid chromatographyDosage formAnalytical Chemistrychemistry.chemical_compoundColumn chromatographyMicellar liquid chromatographyDrug DiscoveryIndicators and ReagentsSpectrophotometry UltravioletDerivatizationAzo CompoundsQuantitative analysis (chemistry)Chromatography High Pressure LiquidMicellesSpectroscopyAntibacterial agentJournal of Pharmaceutical and Biomedical Analysis
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