Search results for "SAP"

showing 10 items of 1142 documents

Bafouoside C, a new triterpenoid saponin from the roots of Cussonia bancoensis Aubrev. & Pellegr.

2014

Abstract A new triterpenoid saponin named bafouoside C 3-O-β- d -glucopyranosyl-(1 → 4)-[β- d -galactopyranosyl-(1 → 2)]-β- d -glucuronopyranosyloleanolic acid 28-O-β- d -glucopyranosyl ester; (1), together with five known compounds 3-O-β- d -galactopyranosyl-(1 → 2)-β- d -glucuronopyranosyloleanolic acid (2), 23-hydroxyursolic acid (3), 28-O-α- l -rhamnopyranosyl-(1 → 4)-O-β- d -glucopyranosyl-(1 → 6)-O-β- d -glucopyranosyl-23-hydroxyursolic acid (4), 3-O-β- d -glucopyranosyl-23-hydroxyursolic acid (5), and 3-O-α- l -arabinopyranosyl-23-hydroxyursolic acid (6), were isolated from the roots of Cussonia bancoensis Aubrev. & Pellegr. Their structures were established on the basis of 1D- and 2…

chemistry.chemical_classificationbiologyCussoniaStereochemistryPlant Sciencebiology.organism_classificationBiochemistryNmr datachemistryCarcinoma CellAraliaceaeAgronomy and Crop ScienceHuman breastTwo-dimensional nuclear magnetic resonance spectroscopyHuman colonBiotechnologyTriterpenoid saponin
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A New Steroidal Saponin from Dioscorea cayenensis

2004

The new 26-O-beta-D-glucopyranosyl-3beta,26-dihydroxy-20,22-seco-25(R)-furost-5-en-20,22-dione-3-O-alpha-L-rhamnopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-(1-->4)-[alpha-L-rhamnopyranosyl-(1-->2)]-beta-D-glucopyranoside (1), along with the known methyl protodioscin (2), asperoside (3) and prosapogenin A of dioscin (4) were isolated from the rhizomes of Dioscorea cayenensis LAM.-HOLL (Dioscoreaceae). Their structures were established mainly on the basis of 600 MHz 2D-NMR spectral data. 4 exhibited antifungal activity against the human pathogenic yeasts Candida albicans, C. glabrata and C. tropicalis (MICs of 20.8, 6.25, 25 microg/ml, respectively), whereas saponins 1-3 were inactive.

chemistry.chemical_classificationbiologyDioscoreaPlant ExtractsStereochemistryDioscoreaceaeProtodioscinSaponinProsapogenin APhytosterolsGeneral ChemistryGeneral MedicineSaponinsbiology.organism_classificationRhizomechemistry.chemical_compoundchemistryCandida albicansDrug DiscoveryHumansDioscorea cayenensisDioscoreaCandida albicansRhizomeChemical and Pharmaceutical Bulletin
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Spirostane and cholestane glycosides from the bulbs of Allium nigrum L

2011

Abstract A phytochemical investigation of the fresh bulbs of Allium nigrum L. led to the isolation of new spirostane-type glycosides as two inseparable isomer mixtures, nigrosides A1/A2 (1a/1b) and nigrosides B1/B2 (2a/2b), two new cholestane-type glycosides, nigrosides C and D (3 and 4), together with the known compounds, 25(R,S)-5α-spirostan-2α,3β,6β-trio1-3-O-β- d -glucopyranosyl-(1 → 2)-O-[β- d -xylopyranosyl-(1 → 3)]-O-β- d -glucopyranosyl-(1 → 4)-β- d -galactopyranoside (5a/5b) and 25(R,S)-5α-spirostan-2α,3β,6β-trio1 3-O-β- d -glucopyranosyl-(1 → 2)-O-[4-O-(3S)-3-hydroxy-3-methylglutaryl-β- d -xylopyranosyl-(1 → 3)]-O-β- d -glucopyranosyl-(1 → 4)-β- d -galactopyranoside (6a/6b), isola…

chemistry.chemical_classificationbiologyLiliaceaeStereochemistrySaponinGlycosideGeneral Medicinebiology.organism_classificationAllium nigrumAnalytical Chemistrychemistry.chemical_compoundchemistryPhytochemicalAlliumCholestaneTwo-dimensional nuclear magnetic resonance spectroscopyFood ScienceFood Chemistry
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Mimonoside D: a new triterpenoid saponin from Mimosa diplotricha Sauvalle (Fabaceae)

2021

A new triterpenoid saponin (Mimonoside D: 3-O-��-L-arabinopyranosyl-3��-hydroxyolean-12-en-28-oic acid 28-O-��-D-xylopyranosyl-(1���2)-��-D- glucopyranoside ester (1)) was isolated from the aerial parts of Mimosa diplotricha Sauvalle together with nine known compounds: 7,4���-dihydroxyflavone (2), kaempferol (3), lupeol (4), betulinic acid (5), ��-sitosterol (6), ��-sitosterol-3-O-��-D-glucopyranoside (7), lutein (8), 5,2���-dihydroxy-7,4���,5���-trimethoxyflavone (9) and vitexin (10). Their structures were elucidated on the basis of spectroscopic (1 D and 2 D nuclear magnetic resonance) and high-resolution mass spectrometric data as well as by comparison of their spectral data with those o…

chemistry.chemical_classificationbiologyOrganic ChemistryVitexinPlant ScienceFabaceaebiology.organism_classificationBiochemistryProteus mirabilisAnalytical Chemistrychemistry.chemical_compoundchemistryBetulinic acidKaempferolMimosa diplotrichaLupeolNuclear chemistryTriterpenoid saponin
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Triterpene Saponins from Four Species of the Polygalaceae Family

2005

Twelve triterpene saponins were isolated by successive MPLC over silica gel from four species of Polygalaceae: From Polygala ruwenzoriensis, five new saponins 1–5 of which 1–4 as two pairs of (E)/(Z)-isomers, together with the four known compounds tenuifoline, (E)- and (Z)-senegasaponin b, (E)- and (Z)-senegin II, and polygalasaponin XXVIII, from the genus Carpolobia, one new saponin 6 from C. alba and the known arilloside (11) from C. lutea, and another new triterpene glycoside 7 from Polygala arenaria. Their structures were established mainly by 600-MHz 2D-NMR techniques (1H,1H-COSY, TOCSY, NOESY, HSQC, HMBC) as 3-O-(β-D-glucopyranosyl)presenegenin 28-{O-α-L-arabinopyranosyl-(1  4)-O-β-D-…

chemistry.chemical_classificationbiologyStereochemistryOrganic ChemistrySaponinGlycosidePolygalasaponin XXVIIIbiology.organism_classificationBiochemistryPresenegeninCatalysisPolygalaInorganic ChemistryCarpolobiaTriterpenechemistryDrug DiscoveryPolygalaceaePhysical and Theoretical ChemistryHelvetica Chimica Acta
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Saponin with antibacterial activity from the roots of Albizia adianthifolia

2019

AbstractAn unprecedented saponin is being reported herein together with five known compounds from the methanol extract of the roots of Albizia adianthifolia. The metabolites were obtained over repe...

chemistry.chemical_classificationbiologyTraditional medicine010405 organic chemistryChemistryOrganic ChemistrySaponinPlant Sciencebiology.organism_classification01 natural sciencesBiochemistry0104 chemical sciencesAnalytical Chemistry010404 medicinal & biomolecular chemistryAntibacterial activityAlbizia adianthifoliaNatural Product Research
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Saponins as immunoadjuvants and immunostimulants

1999

Saponins are either triterpene or steroid glycosides widely distributed in the plant and animal kingdom and include a large number of biologically active compounds. Most of them have surface-active and cholesterol-binding properties.

chemistry.chemical_classificationbiologyTraditional medicineQuillaja saponariaChemistrymedicine.medical_treatmentGlycosideBiological activitySimian immunodeficiency virusmedicine.disease_causebiology.organism_classificationSteroidTriterpenemedicine
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Risk assessment of beauvericin, enniatins and fusaproliferin present in follow-up infant formula by in vitro evaluation of the duodenal and colonic b…

2014

Abstract In this study, 72 samples of follow-up infant formula of Spanish origin were analyzed for the presence of the mycotoxins beauvericin (BEA), enniatins (ENs) (A, A1, B, B1), and fusaproliferin (FUS). The samples analyzed were extracted three times with ethyl acetate and then the mycotoxins were identified and quantified using a liquid chromatography (LC) coupled to a diode array detector (DAD). The positive samples analyzed in this study were digested through a simulated gastrointestinal digestion model, which permit to simulate the physiological condition of the human gastrointestinal tract (duodenal and colonic compartments) in order to assess the bioaccessibility of the bioactive …

chemistry.chemical_compoundFusaproliferinChromatographychemistryInfant formulaChromatography detectorEthyl acetateDigestionMycotoxinBeauvericinIn vitroFood ScienceBiotechnologyFood Control
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On the Occurrence of Flavonoids in the acrocarpous Mosses

1978

Summary By means of paper chromatography two flavonoids were isolated from the methanolic extract of the moss Mnium undulatum. One substance was identified by chromatographic data, absorption spectra and acid hydrolysis as isovitexin-7-0-glucoside (saponarin). The second substance resists acid hydrolysis and is by chromatography and absorption spectrum identical with apigenin-6,8-di-C-glycoside (viccnin).

chemistry.chemical_compoundPaper chromatographyChromatographyAbsorption spectroscopychemistrySaponarinIsovitexinAcid hydrolysisGeneral MedicineZeitschrift für Pflanzenphysiologie
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Effect of soyasaponin I against cytotoxicity and oxidative stress induced by alternariol in Caco-2 cells

2014

chemistry.chemical_compoundSoyasaponin IchemistryBiochemistryCaco-2AlternariolmedicineGeneral MedicineToxicologyCytotoxicitymedicine.disease_causeOxidative stressToxicology Letters
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