Search results for "SIDA"

showing 10 items of 1584 documents

Bidentatoside I, a New Triterpene Saponin from Achyranthes bidentata

2001

Bidentatoside I (1) is a new triterpene saponin bearing an unusual dioxopropionic acid unit, isolated from the roots of Achyranthes bidentata. Structural elucidation was performed mainly by chemical and homo- and heteronuclear 2D NMR techniques. This compound did not show any potentiation of the in vitro cytotoxicity of cisplatin in the HT 29 human colon cancer cell line.

Magnetic Resonance SpectroscopyStereochemistrySaponinPharmaceutical ScienceAntineoplastic AgentsUronic acidPharmacognosyAnalytical ChemistryMagnoliopsidachemistry.chemical_compoundTriterpeneDrug DiscoveryTumor Cells CulturedHumansAchyranthes bidentataPharmacologychemistry.chemical_classificationbiologyOrganic ChemistryGlycosideSaponinsbiology.organism_classificationTriterpenesTerpenoidModels ChemicalComplementary and alternative medicinechemistryBiochemistryHeteronuclear moleculeColonic NeoplasmsMolecular MedicineDrug Screening Assays AntitumorJournal of Natural Products
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Essential Oil Composition of

2019

Drug resistance is a major obstacle in antibiotic and antitumor chemotherapy. In response to the necessity to find new therapeutic strategies, plant secondary metabolites including essential oils (EOs) may represent one of the best sources. EOs in plants act as constitutive defenses against biotic and abiotic stress, and they play an important role in the pharmacology for their low toxicity, good pharmacokinetic and multitarget activity. In this context, natural products such as EOs are one of the most important sources of drugs used in pharmaceutical therapeutics. The aim of this paper was to identify the chemical composition of the essential oil of Alluaudia procera leaves, obtained by hy…

MagnoliopsidaMolecular StructureSpectrum AnalysisPhytochemicalsDrug ResistanceOils VolatileAntineoplastic AgentsArticleessential oilacute myeloid leukemia cellAnti-Bacterial AgentsDidiereaceaesucculent plantsMolecules (Basel, Switzerland)
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La estigmatización del VIH/SIDA: La respuesta desde el trabajo social

2018

El SIDA/VIH es la enfermedad de la inmunodeficiencia humana, siendo el VIH el virus (la- tente o no) y el SIDA el síndrome ya adquirido en la persona que destruye el sistema inmunológico, y que hace que no se tengan las suficientes defensas para poder combatir cualquier tipo de enfermedad. A pesar de que es una enfermedad conocida y extendida globalmente, la sociedad tiene un gran des- conocimiento sobre sus efectos y la población sigue excluyendo socialmente a las personas afectadas, asociando la enfermedad a colectivos lgtb (lesbianas, gays, transexuales, bisexuales). Esta investigación tiene como objeto normalizar la visión de la sociedad respecto a la enfermedad desde el papel del área …

Malalties transmissibles PrevencióVIH/SIDA Trabajo Social estigmatización social intervención social percepción.Treball socialSida36
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Ricerca di nuovi marcatori, diagnostici e prognostici, nella malattia di Fabry

Malattia di Fabry; microRNA; attività enzimatica; gene GLA; alfa-galattosidasi AMalattia di FabrymicroRNAgene GLAattività enzimaticaalfa-galattosidasi A
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Fibroblasts from bank voles inhabiting Chernobyl have increased resistance against oxidative and DNA stresses

2018

Background Elevated levels of environmental ionizing radiation can be a selective pressure for wildlife by producing reactive oxygen species and DNA damage. However, the underlying molecular mechanisms that are affected are not known. Results We isolated skin fibroblasts from bank voles (Myodes glareolus) inhabiting the Chernobyl nuclear power plant accident site where background radiation levels are about 100 times greater than in uncontaminated areas. After a 10 Gy dose of gamma radiation fibroblasts from Chernobyl animals recovered faster than fibroblasts isolated from bank voles living in uncontaminated control area. The Chernobyl fibroblasts were able to sustain significantly higher do…

Male0301 basic medicinep53Antioxidantmedicine.medical_treatment010501 environmental sciences01 natural sciencesAntioxidantsIonizing radiationsäteilybiologiachemistry.chemical_classificationCell DeathbiologyArvicolinaelcsh:CytologyBank volefibroblastitOxidantshumanitiesCell biologyAntioxidant capacityBank voleResearch ArticleG2 PhaseCell SurvivalDNA damagemetsämyyräOxidative phosphorylationCell LineMicrobiologyChernobyl03 medical and health sciencesmedicineAnimalsEnvironmental ionizing radiationlcsh:QH573-671Geneoksidatiivinen stressi0105 earth and related environmental sciencesantioksidantitReactive oxygen speciesCell Cycle CheckpointsDNACell BiologyFibroblastsbiology.organism_classificationresistenssiOxidative Stress030104 developmental biologyChernobyl Nuclear AccidentchemistryGamma RaysApoptosisbank volesDNA damageTumor Suppressor Protein p53BMC Cell Biology
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Comparison of body mass index (BMI) with the CUN-BAE body adiposity estimator in the prediction of hypertension and type 2 diabetes

2016

BACKGROUND: Obesity is a world-wide epidemic whose prevalence is underestimated by BMI measurements, but CUN-BAE (Clínica Universidad de Navarra - Body Adiposity Estimator) estimates the percentage of body fat (BF) while incorporating information on sex and age, thus giving a better match. Our aim is to compare the BMI and CUN-BAE in determining the population attributable fraction (AFp) for obesity as a cause of chronic diseases. METHODS: We calculated the Pearson correlation coefficient between BMI and CUN-BAE, the Kappa index and the internal validity of the BMI. The risks of arterial hypertension (AHT) and diabetes mellitus (DM) and the AFp for obesity were assessed using both the BMI a…

Male:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Physical Examination::Anthropometry [Medical Subject Headings]:Health Care::Environment and Public Health::Public Health::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cross-Sectional Studies [Medical Subject Headings]ObesidadType 2 diabetesÍndice de masa corporalCUN-BAEBody Mass Index:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Diabetes mellitus0302 clinical medicineMedicine030212 general & internal medicineBody mass indexAdiposity:Persons::Persons::Age Groups::Adult::Aged [Medical Subject Headings]education.field_of_studyDiabetisAnthropometryDiabetes:Diseases::Pathological Conditions Signs and Symptoms::Signs and Symptoms::Body Weight::Overweight::Obesity [Medical Subject Headings]Middle Aged:Anatomy::Tissues::Connective Tissue::Adipose Tissue [Medical Subject Headings]CausalityAdipose TissueBody fatHypertensionObesitatFemaleHipertensióResearch ArticleAdultmedicine.medical_specialty:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Anthropometry::Body Weights and Measures::Body Mass Index [Medical Subject Headings]Population:Check Tags::Male [Medical Subject Headings]030209 endocrinology & metabolismBody adiposity index:Health Care::Environment and Public Health::Public Health::Epidemiologic Factors::Causality [Medical Subject Headings]03 medical and health sciences:Diseases::Cardiovascular Diseases::Vascular Diseases::Hypertension [Medical Subject Headings]Population attributable fractionClassification of obesityInternal medicineHipertensiónHumansObesityeducation:Persons::Persons::Age Groups::Adult [Medical Subject Headings]Aged:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Composition::Body Fat Distribution::Adiposity [Medical Subject Headings]Body volume indexbusiness.industryPublic Health Environmental and Occupational Health:Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus Type 2 [Medical Subject Headings]:Persons::Persons::Age Groups::Adult::Middle Aged [Medical Subject Headings]medicine.diseaseObesityCross-Sectional StudiesEndocrinologyDiabetes Mellitus Type 2:Check Tags::Female [Medical Subject Headings]Attributable riskbusinessBody mass indexDemographyAntropometria
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Factores relacionados con el estilo de vida y la condición física que se asocian al IMC en función del género en preadolescentes españoles

2020

Resumen La obesidad se ha convertido en uno de los problemas de salud más graves de la sociedad y se relaciona con multitud de afecciones y complicaciones en la pubertad. Mediante este estudio descriptivo, transversal y poblacional se pretende, en primer lugar, conocer las diferencias entre las variables del estilo de vida y la condición física de cada género y, en segundo lugar, conocer los determinantes relacionados con el estilo de vida y la condición física en una población española de 10 a 12 años de edad con nivel socioeconómico medio. Las variables analizadas fueron el IMC, las variables de condición física (agilidad, flexibilidad y capacidad cardiorrespiratoria) y las variables de l…

MaleAnaerobic ThresholdObesidadMedicine (miscellaneous)Body Mass IndexSex FactorsHumansHábitos saludablesObesityChildExerciseLife StyleBreakfastNutrition and DieteticsFeeding BehaviorAdolescenceCross-Sectional StudiesCardiorespiratory FitnessSocial ClassSpainAdolescenciaFemaleSedentary BehaviorSleepHealthy habitsPhysical Conditioning HumanNutrición Hospitalaria
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Executive Functions Profile in Extreme Eating/Weight Conditions : From Anorexia Nervosa to Obesity

2012

Background: Extreme weight conditions (EWC) groups along a continuum may share some biological risk factors and intermediate neurocognitive phenotypes. A core cognitive trait in EWC appears to be executive dysfunction, with a focus on decision making, response inhibition and cognitive flexibility. Differences between individuals in these areas are likely to contribute to the differences in vulnerability to EWC. The aim of the study was to investigate whether there is a common pattern of executive dysfunction in EWC while comparing anorexia nervosa patients (AN), obese subjects (OB) and healthy eating/weight controls (HC). Methods: Thirty five AN patients, fifty two OB and one hundred thirty…

MaleAnorexia NervosaEating DisordersObesidadNeuropsychological TestsAudiologySocial and Behavioral Sciences:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Executive FunctionCognitionCognitive neurologyWisconsin Card Sorting TestImagen CorporalHuman PerformancePsychology:Psychiatry and Psychology::Mental Disorders::Eating Disorders::Anorexia Nervosa [Medical Subject Headings]Anorexia NerviosaPsychiatryMultidisciplinaryQCognitive flexibilityRNeuropsychological testingAnorèxia nerviosaMiddle AgedExecutive functionsToma de ConcienciaClinical PsychologyMental HealthPruebas NeuropsicológicasAnorexia nervosa (differential diagnoses)Eating disordersMedicineObesitatFemalemedicine.symptomConducta compulsivaResearch ArticleAdultmedicine.medical_specialtyImpulsivityAdolescentScienceDecision MakingPes corporalBiologyImpulsivityYoung AdultNeuropsychologymedicineHumansObesityTrastorns de la conducta alimentàriaNutritionBehavior:Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Cognition::Awareness [Medical Subject Headings]Trastorno por Déficit de Atención con HiperactividadAnorexia nervosaBody weight:Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity [Medical Subject Headings]Impulsive Behavior:Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychological Tests::Neuropsychological Tests [Medical Subject Headings]:Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Perception::Body Image [Medical Subject Headings]NeurocognitiveDecision making:Psychiatry and Psychology::Mental Disorders::Mental Disorders Diagnosed in Childhood::Attention Deficit and Disruptive Behavior Disorders::Attention Deficit Disorder with Hyperactivity [Medical Subject Headings]Stroop effectExecutive dysfunction
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The nutrigenetic influence of the interaction between dietary vitamin E and TXN and COMT gene polymorphisms on waist circumference: a case control st…

2015

Background Abdominal obesity (AO) is a common modifiable risk factor for certain non-communicable diseases associated with enhanced oxidative stress (OS). The objective of this work was to investigate whether the interaction between antioxidant vitamin intake and OS-related polymorphisms modulates gene-associated anthropometry in a Spanish population. Methods A total of 246 subjects with AO, and 492 age and gender matched non-AO subjects were included in the study. Anthropometric, biochemical, and OS parameters, and antioxidant dietary intake data were assessed using validated procedures. DNA from white blood cells was isolated and the genotype of seven polymorphisms from genes involved in …

MaleAntioxidantPolimorphismmedicine.medical_treatment:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Thioredoxins [Medical Subject Headings]Antioxidantes:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Probability::Risk::Risk Factors [Medical Subject Headings]AntioxidantsVitamin E intakeObesidad abdominalchemistry.chemical_compoundNutrigenomicsThioredoxinsPolymorphism (computer science):Anatomy::Cells::Blood Cells::Leukocytes [Medical Subject Headings]Risk FactorsGenotypeVitamin E:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleosides::Deoxyribonucleosides::Deoxyguanosine [Medical Subject Headings]:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Growth Substances::Micronutrients::Vitamins [Medical Subject Headings]:Phenomena and Processes::Metabolic Phenomena::Metabolism::Oxidative Stress [Medical Subject Headings]Abdominal obesityNutrigenómicaMedicine(all)AnthropometryAge FactorsGeneral MedicineAbdominal obesity:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight::Overweight::Obesity::Obesity Abdominal [Medical Subject Headings]Middle Aged:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Models Statistical::Logistic Models [Medical Subject Headings]Waist circumferenceDietaFemale:Phenomena and Processes::Genetic Phenomena::Genotype [Medical Subject Headings]medicine.symptomFactores de riesgoVitaminAdultmedicine.medical_specialtyGenotypeVitamina ECatechol-O-methyltransferaseBiology:Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Diet [Medical Subject Headings]:Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Genes Reporter [Medical Subject Headings]Catechol O-Methyltransferase:Chemicals and Drugs::Biological Factors::Pigments Biological::Carotenoids::Retinoids::Vitamin A [Medical Subject Headings]Polymorphism Single NucleotideGeneral Biochemistry Genetics and Molecular BiologySex FactorsInternal medicine:Chemicals and Drugs::Inorganic Chemicals::Oxygen Compounds::Reactive Oxygen Species [Medical Subject Headings]:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Protective Agents::Antioxidants [Medical Subject Headings]medicinePerímetro abdominal:Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Waist Circumference [Medical Subject Headings]:Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds 2-Ring::Benzopyrans::Vitamin E [Medical Subject Headings]HumansObesityPolymorphismThioredoxinAgedCatechol-O-methyl transferaseBiochemistry Genetics and Molecular Biology(all)Vitamin EResearchCase-control studyGenes informadores:Disciplines and Occupations::Natural Science Disciplines::Biological Science Disciplines::Biology::Genetics::Genomics::Nutrigenomics [Medical Subject Headings]DietOxidative StressEndocrinologychemistrySpainOxidative stressCase-Control Studies:Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Transferases::One-Carbon Group Transferases::Methyltransferases::Catechol O-Methyltransferase [Medical Subject Headings]:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleic Acids::DNA [Medical Subject Headings]Genotipo
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Cardiovascular fitness in youth: association with obesity and metabolic abnormalities

2014

[ES] Las terapias que se implantan actualmente para la obesidad se centran en los aspectos nutricionales y sobre la actividad física. Con el fin de hacer que la actividad física sea una terapia positiva en vez de un desencadenador de discapacidades, es relevante evaluar de forma precisa el entrenamiento cardiovascular. Objetivo: evaluar el entrenamiento cardiovascular midiendo el consumo máximo de oxígeno y evaluar su relación con los parámetros cardiometabólicos clásicos. Métodos: se aplicó el protocolo modificado de Balke a 126 individuos caucásicos (60 % de varones), con edades entre 9 y 16 años, que se sometieron a una evaluación de obesidad. El grupo de no obesos consistía de individuo…

MaleChildren and adolescentsEntrenamiento cardiovascularAdolescentAnaerobic ThresholdExercise testObesidadAdolescentsTECNOLOGIA ELECTRONICAMetabolic DiseasesPredictive Value of TestsHumansCorObesityCardiovascular fitnessChildNiños y adolescentesNutriciólcsh:RC620-627Sistema cardiovascularTrastorns de la nutrició en els infantsVO2 peaklcsh:Nutritional diseases. Deficiency diseasesPhysical FitnessVO2 máximoExercise TestObesitatFemalePrueba de esfuerzoInfantsNutrición Hospitalaria
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