Search results for "SITE"
showing 10 items of 8388 documents
Effects of hydrogen-charging on the properties of S235JR steel
2017
The paper presents the test results of the S235JR steel susceptibility to damage under the influence of hydrogen. The test of mechanical properties was performed on the basis of a static stretch test of non-hydrogenated samples and after cathodic polarization. Electrochemical measurements for the assessment of corrosion resistance of non-hydrogenated and hydrogenated steels were carried out using open circuit potential measurement and registering of potentiodynamic polarization curves in a three-electrode measuring system. Hydrogenation was carried out for between 3 and 24 hours in a solution of 0.1 N sulfuric acid (VI) with the addition of 2 mg/dm 3 of arsenic oxide (III) at an electric cu…
Suction controlled drying and wetting cycle effects on the volumetric behaviour of a lime-treated high plasticity clay
2016
The paper presents some experimental results collected on samples recovered from an experimental embankment obtained by compacting a lime-treated clay. Samples were collected soon after the in situ compaction and they were cured in controlled environmental conditions for at least 18 months. Mercury intrusion porosimetry tests (MIP) were carried out on freeze-dried specimens to characterize the microstructure of the material. In order to assess the durability of the improved material, laboratory tests focused on the effects of cyclic variations of the degree of saturation on the water retention properties and the volumetric behaviour of the stabilized clay. Collected results show that the li…
Accuracy of Saturated Soil Hydraulic Conductivity Estimated from Numerically Simulated Single‐Ring Infiltrations
2019
The single-ring pressure infiltrometer (PI) method is widely used to determine saturated soil hydraulic conductivity, K s , directly in the field. The original and still most common way to analyze the data makes use of the steady-state model developed by the Canadian School in the 90s and two (two-ponding-depth, TPD, approach) or more (multiple-ponding-depth, MPD, approach) depths of ponding. The so-called Wu method based on a generalized infiltration equation allows analysis of the transient infiltration data collected by establishing a single ponding depth of water on the infiltration surface. This investigation, making use of simulated infiltration runs for initially unsaturated sand to …
Generation of Natural Runoff Monthly Series at Ungauged Sites Using a Regional Regressive Model
2016
Many hydrologic applications require reliable estimates of runoff in river basins to face the widespread lack of data, both in time and in space. A regional method for the reconstruction of monthly runoff series is here developed and applied to Sicily (Italy). A simple modeling structure is adopted, consisting of a regression-based rainfall–runoff model with four model parameters, calibrated through a two-step procedure. Monthly runoff estimates are based on precipitation, temperature, and exploiting the autocorrelation with runoff at the previous month. Model parameters are assessed by specific regional equations as a function of easily measurable physical and climate basin descriptors. Th…
Baseline Gut Microbiota Composition Is Associated With Schistosoma mansoni Infection Burden in Rodent Models
2020
In spite of growing evidence supporting the occurrence of complex interactions between Schistosoma and gut bacteria in mice and humans, no data is yet available on whether worm-mediated changes in microbiota composition are dependent on the baseline gut microbial profile of the vertebrate host. In addition, the impact of such changes on the susceptibility to, and pathophysiology of, schistosomiasis remains largely unexplored. In this study, mice colonized with gut microbial populations from a human donor (HMA mice), as well as microbiota-wild type (WT) animals, were infected with Schistosoma mansoni, and alterations of their gut microbial profiles at 50 days post-infection were compared to …
Prediction of Specific TCR-Peptide Binding From Large Dictionaries of TCR-Peptide Pairs
2019
Abstract The T cell repertoire is composed of T cell receptors (TCR) selected by their cognate MHC-peptides and naive TCR that do not bind known peptides. While the task of distinguishing a peptide-binding TCR from a naive TCR unlikely to bind any peptide can be performed using sequence motifs, distinguishing between TCRs binding different peptides requires more advanced methods. Such a prediction is the key for using TCR repertoires as disease-specific biomarkers. We here used large scale TCR-peptide dictionaries with state-of-the-art natural language processing (NLP) methods to produce ERGO (pEptide tcR matchinG predictiOn), a highly specific classifier to predict which TCR binds to which…
THE ROLE OF EXTRACELLULAR VESICLES IN MODULATING THE HOST IMMUNE RESPONSE DURING PARASITIC INFECTIONS
2014
Parasites are the cause of major diseases affecting billions of people. As the inflictions caused by these parasites affect mainly developing countries, they are considered as neglected diseases. These parasitic infections are often chronic and lead to significant immunomodulation of the host immune response by the parasite, which could benefit both the parasite and the host and are the result of millions of years of co-evolution. The description of parasite extracellular vesicles (EVs) in protozoa and helminths suggests that they may play an important role in host–parasite communication. In this review, recent studies on parasitic (protozoa and helminths) EVs are presented and their potent…
Antigen-specific T cells and cytokines detection as useful tool for understanding immunity against zoonotic infections.
2012
Zoonoses include a broad range of diseases, that are becoming of great interest, due to the climate changing, that cause the adaptation of vectors to new niches and environments. Host immune responses play a crucial role in determining the outcome of infections, as documented by expansion of antigen-specific T cells during several zoonotic infections. Thus, understanding of the contribution of antigen-specific T-cell subsets in the host immune response is a powerful tool to evaluate the different immunological mechanisms involved in zoonotic infections and for the development of effective vaccines. In this paper we discuss the role of T cells in some eukaryotic and prokaryotic infectious mo…
Real estate surfaces appraisal
2014
In the appraisal of the market value of the properties are applied two important surface indexes: the market surface ratio of the secondary surfaces and the ratio of the site value to total value (allocation method). The measure of both these indexes can be revealed difficult: the data collection of the surface trade ratio in the market can get different results and in practice often the valuer refolds on the fixed coefficients brought in the handbooks and in the circulars of the public administration; the appraisal of the ratio of the site, especially in the central zones and for ancient buildings, where besides the incidence is higher, is developed extrapolating the ratios from the periph…
How hotel websites may discursively adjust to customer preferences using online criticism
2019
This paper explores discursive ways in which hotels may improve their own websites using online criticism to adjust to customer preferences. To this end, a combined method was used, consisting of a netnographic approach (Kozinet, 2010; Mkono, 2011, 2012) together with an interpersonal discourse framework (Hyland, 2008) applied to e-tourism genres (Suau-Jiménez, 2012, 2016). Four hotel websites, together with 200 corresponding negative reviews from TripAdvisor, were diachronically analyzed to identify common topics. Attitudinals were sough, being the core markers of online critiques, as well as boosters, acting as enhancing markers in hotel websites and paralleling criticized topics. Results…