Search results for "Sensitivity test"

showing 10 items of 355 documents

Induction of Secondary Metabolites from the Marine-Derived Fungus Aspergillus versicolor through Co-cultivation with Bacillus subtilis

2019

AbstractA new cyclic pentapeptide, cotteslosin C (1), a new aflaquinolone, 22-epi-aflaquinolone B (3), and two new anthraquinones (9 and 10), along with thirty known compounds (2, 4 – 8, 11 – 34) were isolated from a co-culture of the sponge-associated fungus Aspergillus versicolor with Bacillus subtilis. The new metabolites were only detected in the co-culture extract, but not when the fungus was grown under axenic conditions. Furthermore, the co-culture extract exhibited an enhanced accumulation of the known constituents versicolorin B (14), averufin (16), and sterigmatocyctin (19) by factors of 1.5, 2.0, and 4.7, respectively, compared to the axenic fungal culture. The structures of the …

Circular dichroismMagnetic Resonance SpectroscopyStereochemistryPharmaceutical ScienceAnthraquinonesMicrobial Sensitivity TestsBacillus subtilisQuinolonesGram-Positive BacteriaPeptides CyclicMass SpectrometryAnalytical ChemistryMicechemistry.chemical_compoundTermészettudományokCell Line TumorDrug DiscoveryAnthraquinonesAnimalsKémiai tudományokAxenicPharmacologyDose-Response Relationship DrugbiologyCytotoxinsChemistryCircular DichroismOrganic ChemistryAbsolute configurationbiology.organism_classificationCoculture TechniquesAnti-Bacterial AgentsAspergillusComplementary and alternative medicineMolecular MedicineAspergillus versicolorAntibacterial activityBacteriaBacillus subtilisPlanta Medica
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Azacoccones F-H, new flavipin-derived alkaloids from an endophytic fungus Epicoccum nigrum MK214079.

2020

Abstract Three new flavipin-derived alkaloids, azacoccones F-H (1–3), along with six known compounds (4–9) were isolated from the endophytic fungus Epicoccum nigrum MK214079 associated with leaves of Salix sp. The structures of the new compounds were established by analysis of their 1D/2D nuclear magnetic resonance (NMR) and high-resolution electrospray ionization mass spectroscopy (HRESIMS) data. The absolute configuration of azacoccones F-H (1–3) was determined by comparison of experimental electronic circular dichroism (ECD) data with reported ones and biogenetic considerations. Epicocconigrone A (4), epipyrone A (5), and epicoccolide B (6) exhibited moderate antibacterial activity again…

Circular dichroismStaphylococcus aureusAntifungal AgentsStereochemistryUstilagoElectrospray ionizationAntineoplastic AgentsMicrobial Sensitivity Testsmedicine.disease_cause01 natural sciencesRussiaMinimum inhibitory concentrationMiceAlkaloidsAscomycotaCell Line TumorDrug DiscoverymedicineEndophytesAnimalsPharmacologyBiological ProductsbiologyMolecular Structure010405 organic chemistryChemistryBasidiomycotaAbsolute configurationSalixGeneral Medicinebiology.organism_classification0104 chemical sciencesAnti-Bacterial AgentsPlant Leaves010404 medicinal & biomolecular chemistryStaphylococcus aureusAntibacterial activityEpicoccum nigrumo-PhthalaldehydeFitoterapia
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Environment- and sequence-dependent modulation of the double-stranded to single-stranded conformational transition of gramicidin A in membranes.

1998

The role of the membrane lipid composition and the individual Trp residues in the conformational rearrangement of gramicidin A along the folding pathway to its channel conformation has been examined in phospholipid bilayers by means of previously described size-exclusion high-performance liquid chromatography HPLC-based strategy (Bano et al. (1991) Biochemistry 30, 886). It has been demonstrated that the chemical composition of the membrane influences the transition rate of the peptide rearrangement from double-stranded dimers to beta-helical monomers. The chemical modification of Trp residues, or its substitution by the more hydrophobic residues phenylalanine or naphthylalanine, stabilized…

Circular dichroismStereochemistryProtein ConformationDimerPhenylalanineEnterococcus faeciumLipid BilayersMolecular Sequence DataPeptideMicrobial Sensitivity TestsBiochemistrychemistry.chemical_compoundProtein structureAmino Acid SequencePeptide sequenceChromatography High Pressure Liquidchemistry.chemical_classificationChemistryCholestenesCircular DichroismGramicidinTryptophanFolding (chemistry)MembraneSpectrometry FluorescenceAmino Acid SubstitutionGramicidinFatty Acids UnsaturatedPhosphatidylcholinesDimerizationBiochemistry
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Comparison of the activity of antifungal hexapeptides and the fungicides thiabendazole and imazalil against postharvest fungal pathogens

2003

8 pages, 2 figures, 3 tables.-- PMID: 14623382 [PubMed].-- Printed version published Dec 31, 2003.

CitrusAntimicrobial peptidesCitrus fruitsMicrobial Sensitivity TestsMicrobiologyMicrobiologyMinimum inhibitory concentrationRhizopusFood PreservationThiabendazolePostharvestFungicidesPenicillium digitatumDose-Response Relationship DrugbiologyImidazolesPenicilliumfood and beveragesGeneral MedicineAlternariabiology.organism_classificationAntimicrobialFungicides IndustrialFungicideFruitPenicilliumAntimicrobial peptidesOligopeptidesFood ScienceInternational Journal of Food Microbiology
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Seasonal variations of antimicrobial activity and chemical composition of essential oils extracted from three Citrus limon L. Burm. cultivars

2014

In order to investigate the seasonal variations of antimicrobial properties and chemical composition of essential oils (EOs), three different cultivars of Citrus limon L. Burm. spp. (Femminello Santa Teresa, Monachello and Femminello Continella) were collected at 6-week intervals, from December 2012 to April 2013, for a total of four harvests. The EOs were extracted from lemon peel by hydro-distillation. The antimicrobial activity, tested by paper disc diffusion method, was evaluated against common food-related pathogenic bacteria (Listeria monocytogenes, Staphylococcus aureus, Salmonella enterica and Enterobacter spp.). EOs were more effective against Gram-positive than Gram-negative bacte…

CitrusStaphylococcus aureusfoodborne pathogenSettore AGR/13 - Chimica AgrariaEnterobacterMicrobial Sensitivity TestsPlant ScienceSettore MED/42 - Igiene Generale E Applicatamedicine.disease_causeBiochemistryessential oilGas Chromatography-Mass SpectrometryAnalytical Chemistryantibacterial activityAnti-Infective AgentsGram-Negative BacteriaBotanyOils Volatilemedicinechemical compositionCultivarChemical compositionbiologyseasonal variationsOrganic ChemistrySalmonella entericaPathogenic bacteriaEnterobacterAntimicrobialbiology.organism_classificationListeria monocytogenesSettore AGR/03 - Arboricoltura Generale E Coltivazioni ArboreeHorticulturelemon fruitItalyFruitSeasonsGas chromatographyGas chromatography–mass spectrometryAntibacterial activitySettore AGR/16 - Microbiologia Agraria
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Zn(II)-alloferon complexes - Similar sequence, different coordination modes, no antibacterial activity.

2020

Often, in the search for a highly defined scientific phenomenon, a different one becomes apparent. This was also the case of this work, in the scope of which we planned to search for metal-enhanced, novel antibacterial/ antifungal compounds. Instead, we denied the existence of such and revealed the details of the bioinorganic chemistry of Zn(II)-alloferon complexes. Zinc(II) complexes of alloferon 1 and 2, ligands with a sequential difference of one amino acid only, show a substantially different coordination pattern at physiological pH. In the case of Zn(II)-alloferon 1 species, a histamine-like binding mode is observed (N-terminal amine and imidazole of His-1) and the coordination sphere …

Coordination sphereAlloferon; Metal-antimicrobial peptide complex; Metal-peptide thermodynamics; Zinc(II)StereochemistryProton Magnetic Resonance Spectroscopychemistry.chemical_elementZincMicrobial Sensitivity Tests010402 general chemistryLigands01 natural sciencesBiochemistryMass SpectrometryInorganic ChemistryAlloferonchemistry.chemical_compoundStructure-Activity RelationshipCoordination ComplexesImidazoleMetal-antimicrobial peptide complexHistidineAmino Acid Sequencechemistry.chemical_classificationMetal-peptide thermodynamics010405 organic chemistryBioinorganic chemistryZinc(II)0104 chemical sciencesAmino acidAnti-Bacterial AgentsZincchemistryThermodynamicsChemical stabilityAmine gas treatingAntibacterial activityPeptidesJournal of inorganic biochemistry
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Mechanisms of quinolone resistance in Aeromonas species isolated from humans, water and eels.

2009

Mechanisms of resistance were determined in 33 quinolone-resistant isolates of the species Aeromonas hydrophila, Aeromonas caviae, Aeromonas media, Aeromonas salmonicida, Aeromonas popoffii and Aeromonas veronii, recovered from humans, freshwater and eels. The quinolone resistance-determining regions (QRDRs) of gyrA and parC genes were sequenced in these resistant strains, as well as in 8 quinolone-sensitive Aeromonas used as controls. All quinolone-resistant Aeromonas carried point mutations in the gyrA QRDR at codon 83, respectively giving rise to substitutions Ser(83)-->Ile (32 strains) or Ser(83)-->Val (1 strain). Almost half of these isolates (48%) carried additional point mutations in…

DNA Topoisomerase IVDNA BacterialAeromonas caviaemedicine.drug_classDNA Mutational AnalysisMutation MissenseDrug resistanceMicrobial Sensitivity TestsQuinolonesMicrobiologyMicrobiologyBacterial ProteinsDrug Resistance BacterialmedicineAnimalsHumansPoint MutationMolecular BiologyEelsbiologyGeneral MedicineSequence Analysis DNAbiochemical phenomena metabolism and nutritionQuinolonebiology.organism_classificationAnti-Bacterial AgentsAeromonas hydrophilaAeromonas salmonicidaAeromonasAmino Acid SubstitutionDNA GyraseAeromonas mediaAeromonasGram-Negative Bacterial InfectionsWater MicrobiologyAeromonas veroniiResearch in microbiology
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Direct conjugal transfers of Ti plasmid to soil microflora

2002

The bacterial species in soil that can receive a Ti plasmid by conjugation from Agrobacterium spp. were investigated. In order to have direct access to the potential reservoir of Ti plasmid amongst soil microflora, the conjugal system consisting of a multiply auxotrophic derivative of C58 (ST-96-4) and a derivative of pTiC58Delta(acc)R (pSTiEGK) containing a triple antibiotic-resistance cassette in traM was used to transfer the Ti plasmid in a complex soil microflora used as the recipient. Numerous transconjugants were obtained by this method but none was identified as Agrobacterium. This could be explained by the low density of Agrobacterium in the tested soil. As indicated by analysis of …

DNA BacterialAgrobacteriumSequence analysisAuxotrophy[SDV]Life Sciences [q-bio]Molecular Sequence DataMicrobial Sensitivity TestsPolymerase Chain ReactionMicrobiology03 medical and health sciencesTi plasmidRNA Ribosomal 16SGenetics[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular Biology[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyEcology Evolution Behavior and SystematicsPhylogenySoil MicrobiologyComputingMilieux_MISCELLANEOUS030304 developmental biologyDNA Primers0303 health sciencesbiologyBase Sequence030306 microbiologyDrug Resistance MicrobialSequence Analysis DNARibosomal RNAbiology.organism_classificationSinorhizobiumConjugation GeneticMicrobial geneticsSoil microbiologyPolymorphism Restriction Fragment LengthPlasmidsRhizobium
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Aeromonas hydrophila subsp. dhakensis isolated from feces, water and fish in Mediterranean Spain.

2012

Eight Aeromonas hydrophila-like arabinose-negative isolates from diverse sources (i.e., river freshwater, cooling-system water pond, diseased wild European eels, and human stools) sampled in Valencia (Spain) during 2004-2005, were characterized by 16S rRNA gene sequencing and extensive biochemical testing along with reference strains of most Aeromonas species. These isolates and all reference strains of A. hydrophila subsp. dhakensis and A. aquariorum showed a 16S rRNA sequence similarity of 99.8-100%, and they all shared an identical phenotype. This matched exactly with that of A. hydrophila subsp. dhakensis since all strains displayed positive responses to the Voges-Prokauer test and to t…

DNA BacterialFresh WaterMicrobial Sensitivity TestsAmoxicillin-Potassium Clavulanate CombinationCefoxitinFecesDrug Resistance Multiple BacterialRNA Ribosomal 16SAnimalsHumansTicarcillinemerging pathogen16S rRNA gene sequencingBase SequenceSequence Analysis RNAA. hydrophila subsp. dhakensisFishesArticlesbiochemical phenomena metabolism and nutritionbacterial infections and mycosesAeromonas hydrophilaImipenemPhenotypeSpainphenotypic profilebacteriaMicrobes and environments
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Biodiversity and dairy traits of lactic acid bacteria from foliage of aromatic plants before and after dehydration process monitored by a smart senso…

2020

ABSTRACT The main hypothesis of this work was to evaluate the presence of lactic acid bacteria (LAB) intrinsically resistant to plant essential oils in sage (Salvia officinalis L.) and laurel (Laurus nobilis), for future applications in functional cheese production by addition of aromatic herbs. The effect of the drying process on the viability of LAB was evaluated with three biomass densities (3, 4 and 5 kg/m2). The drying densities did not affect weight loss, but influenced the levels of LAB of sage and laurel. A total of 10 different strains of Enterococcus faecium, Enterococcus mundtii, Enterococcus raffinosus and Leuconostoc mesenteroides were identified from laurel, while sage did not…

DNA BacterialHot TemperatureEnterococcus mundtiived/biology.organism_classification_rank.speciesMicrobial Sensitivity TestsMicrobiologyLauraceaefoodLaurus nobilisCheeseLactobacillalesRNA Ribosomal 16Ssmart systemGeneticsdryingFood scienceDesiccationSalvia officinalisMolecular BiologyPhylogenyMicrobial Viabilitybiologyved/biologyChemistryEnterococcus raffinosusSAGESalvia officinalisSettore AGR/09 - Meccanica Agrariafood and beveragesBiodiversitybiology.organism_classificationfood.foodAnti-Bacterial AgentsRandom Amplified Polymorphic DNA Techniquelactic acid bacterialaurelsageEnterococcusLeuconostoc mesenteroidesFood Microbiologydairy potentialSettore AGR/16 - Microbiologia AgrariaEnterococcus faeciumFEMS Microbiology Letters
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