Search results for "Silicon"

showing 10 items of 1391 documents

Sponge biosilica formation involves syneresis following polycondensation in vivo.

2011

Syneresis is a process observed during the maturation/aging of silica gels obtained by sol-gel synthesis that results in shrinkage and expulsion of water due to a rearrangement and increase in the number of bridging siloxane bonds. Here we describe how the process of biosilica deposition during spicule ("biosilica" skeleton of the siliceous sponges) formation involves a phase of syneresis that occurs after the enzyme-mediated polycondensation reaction. Primmorphs from the demosponge Suberites domuncula were used to study syneresis and the inhibition of this mechanism. We showed by scanning electron microscopy that spicules added to primmorphs that have been incubated with manganese sulfate …

SpiculeAquaporin02 engineering and technologyAquaporinsBiochemistry03 medical and health scienceschemistry.chemical_compoundDemospongeSponge spiculeSpectroscopy Fourier Transform InfraredAnimalsMolecular Biology030304 developmental biology0303 health sciencesbiologySyneresisSulfatesOrganic ChemistryWater021001 nanoscience & nanotechnologybiology.organism_classificationSilicon DioxideCathepsinsSilicateSuberites domunculaSpongeBiochemistrychemistryGene Expression RegulationManganese CompoundsThermogravimetryBiophysicsMolecular Medicine0210 nano-technologySuberitesChembiochem : a European journal of chemical biology
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Selenium affects biosilica formation in the demosponge Suberites domuncula

2005

Selenium is a trace element found in freshwater and the marine environment. We show that it plays a major role in spicule formation in the demosponge Suberites domuncula. If added to primmorphs, an in vitro sponge cell culture system, it stimulates the formation of siliceous spicules. Using differential display of transcripts, we demonstrate that, after a 72-h exposure of primmorphs to selenium, two genes are up-regulated; one codes for selenoprotein M and the other for a novel spicule-associated protein. The deduced protein sequence of selenoprotein M (14 kDa) shows characteristic features of metazoan selenoproteins. The spicule-associated protein (26 kDa) comprises six characteristic repe…

SpiculeBlotting WesternMolecular Sequence DataFluorescent Antibody Techniquechemistry.chemical_elementselenium; silica; silicatein; spicules; spongesBiochemistryAntibodiesSeleniumSponge spiculeDemospongeAnimalsAmino Acid SequenceSelenoproteinsMolecular Biologychemistry.chemical_classificationGlutathione PeroxidaseBase SequencebiologyGene Expression ProfilingProteinsCell BiologyAnatomySilicon Dioxidebiology.organism_classificationCathepsinsUp-RegulationAmino acidSuberites domunculaSpongeBiochemistrychemistrySelenoproteinSuberitesSeleniumFEBS Journal
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Evagination of Cells Controls Bio-Silica Formation and Maturation during Spicule Formation in Sponges

2011

The enzymatic-silicatein mediated formation of the skeletal elements, the spicules of siliceous sponges starts intracellularly and is completed extracellularly. With Suberites domuncula we show that the axial growth of the spicules proceeds in three phases: (I) formation of an axial canal; (II) evagination of a cell process into the axial canal, and (III) assembly of the axial filament composed of silicatein. During these phases the core part of the spicule is synthesized. Silicatein and its substrate silicate are stored in silicasomes, found both inside and outside of the cellular extension within the axial canal, as well as all around the spicule. The membranes of the silicasomes are inte…

SpiculeHistologyMaterials ScienceAquaporinlcsh:MedicineMarine BiologyCytoplasmic GranulesModels BiologicalInorganic ChemistryNatural Materials03 medical and health sciencesSponge spiculeMicroscopy Electron TransmissionAnimal PhysiologyNanotechnologyAnimalslcsh:ScienceBiologyBioinorganic Chemistry030304 developmental biologyNanomaterials0303 health sciencesMultidisciplinarybiologyChemistryVesicleSilicates030302 biochemistry & molecular biologylcsh:RCytoplasmic VesiclesSpectrometry X-Ray EmissionAnatomyMarine TechnologyBiogeochemistrybiology.organism_classificationSilicon DioxideCathepsinsImmunohistochemistrySuberites domunculaChemistryMembraneGeochemistryEvaginationBiophysicslcsh:QSuberitesZoologySuberitesResearch ArticlePLoS ONE
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Localization and Characterization of Ferritin in Demospongiae: A Possible Role on Spiculogenesis

2014

Iron, as inorganic ion or as oxide, is widely used by biological systems in a myriad of biological functions (e.g., enzymatic, gene activation and/or regulation). In particular, marine organisms containing silica structures—diatoms and sponges—grow preferentially in the presence of iron. Using primary sponge cell culture from S. domuncula–primmorphs—as an in vitro model to study the Demospongiae spiculogenesis, we found the presence of agglomerates 50 nm in diameter exclusively inside sponge specialized cells called sclerocytes. A clear phase/material separation is observed between the agglomerates and the initial stages of intracellular spicule formation. STEM-HRTEM-EDX analysis of the agg…

SpiculeIronIron oxidePharmaceutical ScienceNanotechnologyFerric CompoundsArticle<i>Suberites domuncula</i>; primmorphs; iron; ferritin; spiculogenesischemistry.chemical_compoundprimmorphsDrug DiscoveryAnimalslcsh:QH301-705.5Pharmacology Toxicology and Pharmaceutics (miscellaneous)Cells CulturedSclerocyteDiatomsbiologyferritinHematitebiology.organism_classificationSilicon DioxideSuberites domunculaspiculogenesisPoriferaFerritinSuberites domunculaSpongelcsh:Biology (General)chemistryvisual_artFerritinsbiology.proteinBiophysicsvisual_art.visual_art_mediumSuberitesSuberitesMarine Drugs
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Crystalline nanorods as possible templates for the synthesis of amorphous biosilica during spicule formation in Demospongiae.

2009

In tandem: High-resolution TEM shows that during the initial stages of demosponge spicule formation, a primordial crystalline structure is formed within the axial filament. The recently developed electron diffraction tomography technique (ADT) reveals that the nanorods have a layered structure that matches smectitic phyllosilicates. These intracellular nanorods have been considered as precursors of mature spicules. High-resolution microscopy shows that, during the initial stages of demosponge spicule formation, a primordial crystalline structure is formed within the axial filament. The recently developed electron diffraction tomography technique reveals that the nanorods have a layered stru…

SpiculeMaterials scienceElectronsCrystal structureBiochemistrybioinorganic chemistryDemospongeSponge spiculeMicroscopy Electron TransmissionX-Ray DiffractionnanostructuresAnimalsMolecular BiologyNanotubesbiologyElectron crystallographysilicateinOrganic Chemistrybioinorganic chemistry; electron crystallography; nanostructures; silicatein; spiculesbiology.organism_classificationSilicon DioxidespiculesAmorphous solidPoriferaCrystallographyelectron crystallographyElectron diffractionMicroscopy Electron ScanningMolecular MedicineNanorodChembiochem : a European journal of chemical biology
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Silicateins - A Novel Paradigm in Bioinorganic Chemistry: Enzymatic Synthesis of Inorganic Polymeric Silica

2013

The inorganic matrix of the siliceous skeletal elements of sponges, that is, spicules, is formed of amorphous biosilica. Until a decade ago, it remained unclear how the hard biosilica monoliths of the spicules are formed in sponges that live in a silica-poor (<50 mu m) aquatic environment. The following two discoveries caused a paradigm shift and allowed an elucidation of the processes underlying spicule formation; first the discovery that in the spicules only one major protein, silicatein, exists and second, that this protein displays a bio-catalytical, enzymatic function. These findings caused a paradigm shift, since silicatein is the first enzyme that catalyzes the formation of an inorga…

SpiculeNew horizonsPolymersNanotechnology02 engineering and technologyCatalysisCalcium Carbonate03 medical and health sciencesSponge spiculeAnimals030304 developmental biology0303 health sciencesInorganic polymerChemistrySilicatesOrganic ChemistrySubstrate (chemistry)Bioinorganic chemistryGeneral ChemistryEnzymatic synthesisSilicon Dioxide021001 nanoscience & nanotechnologyCathepsinsPoriferaChemistry BioinorganicChemical engineeringBiocatalysisInorganic matrixSuberites0210 nano-technology
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Circumferential spicule growth by pericellular silica deposition in the hexactinellid sponge Monorhaphis chuni.

2011

SUMMARY The giant basal spicule of the hexactinellid sponge Monorhaphis chuni represents the longest natural siliceous structure on Earth. This spicule is composed of concentrically arranged lamellae that are approximately 10 μm thick. In the present study, we investigated the formation of outer lamellae on a cellular level using microscopic and spectroscopic techniques. It is shown that the formation of an outermost lamella begins with the association of cell clusters with the surface of the thickening and/or growing spicule. The cells release silica for controlled formation of a lamella. The pericellular (silica) material fuses to a delimited and textured layer of silica with depressions …

SpiculePhysiologyMineralogy02 engineering and technologyAquatic Science03 medical and health sciencesAnimalsComposite materialMolecular BiologyEcology Evolution Behavior and Systematics030304 developmental biology0303 health sciencesbiologyMonorhaphisHexactinellidSpectrometry X-Ray Emission021001 nanoscience & nanotechnologybiology.organism_classificationSilicon DioxideSilica depositionPoriferaSpongeLamella (surface anatomy)Insect ScienceAnimal Science and ZoologyThickening0210 nano-technologyLayer (electronics)The Journal of experimental biology
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Involvement of aquaporin channels in water extrusion from biosilica during maturation of sponge siliceous spicules.

2015

Aquaporins are a family of small, pore-forming, integral cell membrane proteins. This ancient protein family functions as water channels and is found in all kingdoms (including archaea, eubacteria, fungi, plants, and animals). We discovered that in sponges aquaporin plays a novel role during the maturation of spicules, their skeletal elements. Spicules are synthesized enzymatically via silicatein following a polycondensation reaction. During this process, a 1:1 stoichiometric release of water per one Si-O-Si bond formed is produced. The product of silicatein, biosilica, is a fluffy, soft material that must be hardened in order to function as a solid rod. Using the model of the demosponge sp…

SpiculeProtein familyAquaporinWaterBiologybiology.organism_classificationAquaporinsSilicon DioxideCell biologyPoriferaSuberites domunculaSpongeDemospongeSponge spiculeComplementary DNABotanyAnimalsGeneral Agricultural and Biological SciencesThe Biological bulletin
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Magnetic resonance imaging of the siliceous skeleton of the demosponge Lubomirskia baicalensis

2005

The skeletal elements (spicules) of the demosponge Lubomirskia baicalensis were analyzed; they are composed of amorphous, non-crystalline silica, and contain in a central axial canal the axial filament which consists of the enzyme silicatein. The axial filament, that orients the spicule in its longitudinal axis exists also in the center of the spines which decorate the spicule. During growth of the sponge, new serially arranged modules which are formed from longitudinally arranged spicule bundles are added at the tip of the branches. X-ray analysis revealed that these serial modules are separated from each other by septate zones (annuli). We describe that the longitudinal bundles of spicule…

SpiculebiologyAnatomyLubomirskia baicalensisbiology.organism_classificationSilicon DioxideSkeleton (computer programming)Magnetic Resonance ImagingModels BiologicalPoriferaRadiographySpongeDemospongeSponge spiculeNuclear magnetic resonanceApex (mollusc)Structural BiologyMicroscopy Electron ScanningAnimalsLongitudinal axisBody PatterningJournal of Structural Biology
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Axial growth of hexactinellid spicules: Formation of cone-like structural units in the giant basal spicules of the hexactinellid Monorhaphis

2008

The glass sponge Monorhaphis chuni (Porifera: Hexactinellida) forms the largest bio-silica structures on Earth; their giant basal spicules reach sizes of up to 3 m and diameters of 8.5 mm. Previously, it had been shown that the thickness growth proceeds by appositional layering of individual lamellae; however, the mechanism for the longitudinal growth remained unstudied. Now we show, that the surface of the spicules have towards the tip serrated relief structures that are consistent in size and form with the protrusions on the surface of the spicules. These protrusions fit into the collagen net that surrounds the spicules. The widths of the individual lamellae do not show a pronounced size …

SpiculebiologyHexactinellidSilicatesImmunogold labellingSilicon Dioxidebiology.organism_classificationPoriferalaw.inventionSuberites domunculaMicroscopy ElectronSpongeCrystallographySponge spiculeStructural BiologylawAnimalsElectrophoresis Polyacrylamide GelCollagenElectron microscopeElongationSuberitesJournal of Structural Biology
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