Search results for "Simulation"

showing 10 items of 5095 documents

The Impact of Financial Development and Macroeconomic Fundamentals on Nonperforming Loans among Emerging Countries: An Assessment Using the NARDL App…

2022

The relationship between financial development indicators and non-performing loans (NPLs) has garnered significant attention, especially in emerging countries. The puzzle of whether financial sector development increases or decreases Non-performing Loans (NPL)s has not been resolved to the satisfaction of the curious mind. This research attempts to answer the above question by studying the asymmetric and symmetric association between financial sector development and NPLs, by utilizing the novel non-linear autoregressive distribution lag (NARDL) and the linear autoregressive distribution lag (ARDL) approach. Moreover, to make the study inclusive, we have added a series of proxies to measure …

symmetric; asymmetric; NARDL; non-performing loans; emerging countries; developing countriesGeneral Computer ScienceApplied MathematicsModeling and SimulationTheoretical Computer ScienceComputation; Volume 10; Issue 10; Pages: 182
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Synthesis and Structure-Affinity Relationships of Spirocyclic Benzopyrans with Exocyclic Amino Moiety

2019

σ1 and/or σ2 receptors play a crucial role in pathological conditions such as pain, neurodegenerative disorders, and cancer. A set of spirocyclic cyclohexanes with diverse O-heterocycles and amino moieties (general structure III) was prepared and pharmacologically evaluated. In structure-activity relationships studies, the σ1 receptor affinity and σ1:σ2 selectivity were correlated with the stereochemistry, the kind and substitution pattern of the O-heterocycle, and the substituents at the exocyclic amino moiety. cis-configured 2-benzopyran cis-11b bearing a methoxy group and a tertiary cyclohexylmethylamino moiety showed the highest σ1 affinity ( Ki = 1.9 nM) of this series of compounds. In…

synthesisexocyclic amino moietyReceptors Opioid mudocking studieCrystallography X-RayLigands01 natural sciencesopioid receptorschemistry.chemical_compoundProtein structureDrug DiscoveryMoiety0303 health sciencesσ1 receptor ligandsstructure (σ1) affinity relationshipmolecular dynamicBenzyl groupMolecular MedicinesynthesiBenzopyransSelectivityHydrophobic and Hydrophilic Interactionsfree binding enthalpyStereochemistrychange of receptor profileMolecular Dynamics Simulation03 medical and health sciencesStructure-Activity Relationshipσ1 receptor ligands; spirocyclic compounds; benzopyrans; benzofurans; exocyclic amino moiety; synthesis; structure (σ1) affinity relationships; σ1 antagonistic activity; receptor selectivity; molecular dynamics; docking studies; free binding enthalpy; X-ray crystal structure; opioid receptors; MOR affinity; change of receptor profile; structure MOR affinity relationshipsstructure (σ1) affinity relationshipsStructure–activity relationshipHumansReceptors sigmaBenzopyransSpiro Compoundsspirocyclic compoundBinding siteMOR affinity030304 developmental biologybenzopyranbenzofuransσ1 receptor ligandBinding Sitesspirocyclic compoundsreceptor selectivitystructure MOR affinity relationshipsdocking studiesbenzofuranopioid receptorX-ray crystal structuremolecular dynamics0104 chemical sciencesProtein Structure Tertiary010404 medicinal & biomolecular chemistrychemistrySalt bridgeσ1 antagonistic activity
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Evaluation of asset replacement strategies considering economic cycles: lessons from the machinery rental business

2015

Contains fulltext : 144492.pdf (Publisher’s version ) (Open Access) In businesses with heavy capital investments, the effective management of assets is crucial, in particular in the fleet rental business where assets are the major source of revenues. One important question in this regard concerns the replacement of used assets and the purchase of new assets. Thus, the objective of this study is to evaluate performance effects of asset replacement strategies. In order to maximise net cash flow of a rental company for construction machinery, a range of scenarios investigating the timing and nature of policies for replacing the fleet are analysed. Simulation findings are then discussed to gene…

system dynamicFinancereplacement strategysimulation modeleconomic cycle.business.industryResponsible Organizationrental industryRentingCommerceSettore SECS-P/07 - Economia AziendaleCapital (economics)asset managementFixed assetRevenueCash flowAsset managementAsset (economics)businesspolicyUtilizationInternational Journal of Modelling in Operations Management
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Modelling and assessing public health policies to counteract Italian measles outbreaks

2021

This study aims to understand, through explanatory research, the key factors that led to the 2017 measles outbreak in Italy, the causes of the low level of immunisation and the causes of possible cyclical phenomena of measles epidemics. This topic's comprehension has required a holistic approach, merging epidemiological aspects, socioeconomic aspects (including the evolution of mistrust in vaccinations, infodemy and fake news) and health law constraints. A specific SIR System Dynamics (SD) model was built to reproduce the relevant cause-and-effect relationships between social interactions, the public institutions behaviour and the measles outbreaks. SD results permit the assessment of the h…

system dynamicInfodemicPublic healthmedicine.medical_specialtyCommunicable diseaseApplied MathematicsPublic healthVaccinationSir modelMeasles outbreakOutbreakSettore ING-IND/35 - Ingegneria Economico-GestionaleSettore MED/42 - Igiene Generale E Applicatamedicine.diseaseMeaslesComputer Science ApplicationsVaccinationKey factorsGeographySettore SECS-P/07 - Economia AziendaleMeasleModeling and SimulationEnvironmental healthmedicineInternational Journal of Simulation and Process Modelling
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Performance Management in Local Government: The Application of System Dynamics to Promote Data Use

2014

The purpose of this article is to demonstrate how system dynamics can be used to enrich performance management in local government, focusing specifically on how the development of conceptual and simulation system dynamic models can foster a shared view of the relevant system among stakeholders to overcome factors that limit data use. Responding to this purpose, we present a normative case study on how key drivers can be used to foster a shared view of the residential refuse collection system for supporting policy and process changes. A major finding from our research, however, is that performance management cannot overlook the broader forces of citizenship outcomes that impact the community.

system dynamicProcess managementPublic AdministrationPerformance managementbusiness.industrymedia_common.quotation_subjectEnvironmental resource managementdata useSimulation systemSystem dynamicsDynamic modelsSettore SECS-P/07 - Economia AziendaleLocal governmentKey (cryptography)Normativelocal governmentperformance managementBusinessBusiness and International ManagementCitizenshiplocal government performance management system dynamics data usemedia_common
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Use of driving simulators for advanced driver assistance Systems evaluation in emergency situations

2012

Introducing advanced driver assistance systems in cars has numerous consequences, particularly on drivers' behavior and their interaction with the vehicle. The expected safety benefits of assistance systems can thus be jeopardized. In order to assess the actual safety benefits, driving simulators offer a safe and cheap alternative. This doctoral work relies on experiments carried out on driving simulators with different assistance systems. A first experimental part focuses on longitudinal control assistance: we studied drivers' familiarization with a Forward Collision Warning system in critical situations. A second experimental part focuses on lateral control assistance: we studied drivers'…

systèmes d'aide à la conduitedriving simulation[INFO.INFO-GR] Computer Science [cs]/Graphics [cs.GR]advanced driver assistance systemsdriving safety.sécurité routière[ INFO.INFO-GR ] Computer Science [cs]/Graphics [cs.GR]emergency situationssimulation de conduitesituations d'urgence[INFO.INFO-GR]Computer Science [cs]/Graphics [cs.GR]
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CERN IRRADIATION FACILITIES.

2017

CERN provides unique irradiation facilities for applications in dosimetry, metrology, intercomparison of radiation protection devices, benchmark of Monte Carlo codes and radiation damage studies to electronics.

säteilytysPhysics::Instrumentation and DetectorsComputer scienceNuclear engineeringPhysics::Medical PhysicsMonte Carlo methodRadiation Dosage01 natural sciences030218 nuclear medicine & medical imagingradiation physics03 medical and health sciences0302 clinical medicineRadiation ProtectionRadiation Monitoring0103 physical sciencesRadiation damageDosimetryHumansRadiology Nuclear Medicine and imagingComputer SimulationIrradiationNeutronsRadiationLarge Hadron Colliderta114irradiationRadiological and Ultrasound Technology010308 nuclear & particles physicsbusiness.industryPublic Health Environmental and Occupational HealthGeneral MedicineMetrologysäteilyfysiikkaBenchmark (computing)Physics::Accelerator PhysicsRadiation protectionbusinessMonte Carlo MethodRadiation protection dosimetry
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T9+HUD: Physical Keypad and HUD can Improve Driving Performance while Typing and Driving

2016

We introduce T9+HUD, a text entry method designed to decrease visual distraction while driving and typing. T9+HUD combines a physical 3x4 keypad on the steering wheel with a head-up-display (HUD) for projecting output on the windshield. Previous work suggests this may be a visually less demanding way to type while driving than the popular case which requires shifts of visual attention away from the road. We present a prototype design and report first results from a controlled evaluation in a driving simulator. While driving, the T9+HUD text entry rate was equal compared to a dashboard-mounted touchscreen device, but it reduced lane deviations by 70%. Furthermore, there was no significant di…

ta113050210 logistics & transportationComputer science05 social sciencesSignificant differenceDriving simulatorcar interfacesSteering wheelT9law.inventionautomotive user interfacesTouchscreenlawWindshield0502 economics and business11. SustainabilityT9 text inputKeypadVisual attentiontext input0501 psychology and cognitive sciencesVisual distraction050107 human factorsSimulation
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DOBRO : a prediction error correcting robot under drifts

2016

We propose DOBRO, a light online learning module, which is equipped with a smart correction policy helping making decision to correct or not the given prediction depending on how likely the correction will lead to a better prediction performance. DOBRO is a standalone module requiring nothing more than a time series of prediction errors and it is flexible to be integrated into any black-box model to improve its performance under drifts. We performed evaluation in a real-world application with bus arrival time prediction problem. The obtained results show that DOBRO improved prediction performance significantly meanwhile it did not hurt the accuracy when drift does not happen.

ta113Concept driftComputer scienceMean squared prediction error02 engineering and technologyARIMAconcept drifton-line prediction error correction020204 information systems0202 electrical engineering electronic engineering information engineeringRobot020201 artificial intelligence & image processingAutoregressive integrated moving averageSimulation
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Measuring Distraction at the Levels of Tactical and Strategic Control: The Limits of Capacity-Based Measures for Revealing Unsafe Visual Sampling Mod…

2011

The control theory of driving suggests that driver distraction can be analyzed as a breakdown of control at three levels. Common approach for analyzing distraction experimentally is to utilize capacity-based measures to assess distraction at the level of operational control. Three driving simulation experiments with 61 participants were organized to evaluate which kind of measures could be used to analyze drivers' tactical visual sampling models and the related effects of distraction while searching textual information on in-car display. The effects of two different text types were evaluated. The utilized capacity-based measures seemed to be insufficient for revealing participants' tactical…

ta113Control theory (sociology)Article SubjectComputer scienceControl (management)Sampling (statistics)Workloadlcsh:QA75.5-76.95Task (project management)Human-Computer InteractionSAFERDistractionStrategic controllcsh:Electronic computers. Computer scienceSimulationCognitive psychologyAdvances in Human-Computer Interaction
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