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showing 10 items of 4920 documents

Left-Ventricle Segmentation of SPECT Images of Rats

2015

Single-photon emission computed tomography (SPECT) imaging of the heart is helpful to quantify the left-ventricular ejection fraction and study myocardial perfusion scans. However, these evaluations require a 3-D segmentation of the left-ventricular wall on each phase of the cardiac cycle. This paper presents a fast and interactive graph cut method for 3-D segmentation of the left ventricle (LV) of rats in SPECT images. The method is carried out in three steps. First, 3-D sampling of the LV cavity is made in a spherical-cylindrical coordinate system. Then, a graph-cut-based energy minimization procedure provides delineation of the myocardium centerline surface. From there, it is possible to…

[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/ImagingHeart VentriclesBiomedical Engineering030204 cardiovascular system & hematologySingle-photon emission computed tomography030218 nuclear medicine & medical imaging03 medical and health sciences0302 clinical medicineImaging Three-DimensionalCutmedicineAnimalsComputer visionSegmentationLongitudinal Studies[ SDV.IB.IMA ] Life Sciences [q-bio]/Bioengineering/ImagingComputingMilieux_MISCELLANEOUSMathematicsTomography Emission-Computed Single-Photonmedicine.diagnostic_testCardiac cycleOrientation (computer vision)business.industryImage segmentationRatsTomographyArtificial intelligencebusinessEmission computed tomography
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The multiple facets of Cajal-Retzius neurons.

2021

ABSTRACTCajal-Retzius neurons (CRs) are among the first-born neurons in the developing cortex of reptiles, birds and mammals, including humans. The peculiarity of CRs lies in the fact they are initially embedded into the immature neuronal network before being almost completely eliminated by cell death at the end of cortical development. CRs are best known for controlling the migration of glutamatergic neurons and the formation of cortical layers through the secretion of the glycoprotein reelin. However, they have been shown to play numerous additional key roles at many steps of cortical development, spanning from patterning and sizing functional areas to synaptogenesis. The use of genetic l…

[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/NeurobiologyCell Adhesion Molecules NeuronalNeurogenesisSynaptogenesisHippocampusNerve Tissue Proteins[SDV.BC.IC] Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB]BiologyDevelopmentMolecular heterogeneityHippocampusCajal-Retzius neurons03 medical and health sciencesGlutamatergicMolecular profiling0302 clinical medicineCortex (anatomy)[SDV.BC.IC]Life Sciences [q-bio]/Cellular Biology/Cell Behavior [q-bio.CB]Biological neural networkmedicineotorhinolaryngologic diseasesAnimalsHumansReelinMolecular Biology030304 developmental biologyCerebral CortexNeurons0303 health sciencesExtracellular Matrix ProteinsCell DeathSerine Endopeptidases[SDV.NEU.NB] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology[SDV.BDD.EO] Life Sciences [q-bio]/Development Biology/Embryology and OrganogenesisReelin Proteinmedicine.anatomical_structure[SDV.BDD.EO]Life Sciences [q-bio]/Development Biology/Embryology and Organogenesisbiology.proteinCortexIdentification (biology)TranscriptomeNeuroscience030217 neurology & neurosurgerySingle-cell transcriptomicsDevelopmental BiologyDevelopment (Cambridge, England)
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Single cell analysis evidence Heterogeneous expression of the Agr communication system of Listeria monocytogenes

2012

http://prodinra.inra.fr/record/271694EAMERSCT3 EJ3; Communication, often referred as Quorum Sensing, is involved in the adaptation of most bacteria to their environment. In the genus Listeria, the agr communication system affects the biology of Listeria monocytogenes during saprophytic life (biofilm formation) and during infection. In the present study, we investigated in situ agr expression of six isolates of L. monocytogenes by combining gfp reporters, flow cytometry and fluorescent microscopy during plantonic growth and dynamic flow cell biofilm set ups. Unexpectedly, during growth in TSB homogenised liquid cultures incubated at 25°C, while auto-inducer concentration was uniform, statist…

[SDV] Life Sciences [q-bio][ SDV ] Life Sciences [q-bio]listeria monocytogenes[SDV]Life Sciences [q-bio]bacteriabiochemical phenomena metabolism and nutritionheterogeneitysingle cell
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Single crystal EXAFS at high pressure

2000

Abstract We present a new technique for structure characterization under high pressure conditions. The use of an undulator beam of the third-generation ESRF source of synchrotron radiation has enabled the first single crystal EXAFS experiments at high pressure using a diamond anvil cell as pressure generator. Taking advantage of the linear polarization of X-rays the technique becomes an orientation-selective probe of the local structure of materials. We describe the principle of the technique and some applications.

[SPI.ACOU]Engineering Sciences [physics]/Acoustics [physics.class-ph]Materials science[SDU.STU.GP]Sciences of the Universe [physics]/Earth Sciences/Geophysics [physics.geo-ph]business.industryLinear polarizationSynchrotron radiation02 engineering and technologyUndulator021001 nanoscience & nanotechnologyCondensed Matter Physics01 natural sciencesDiamond anvil cellCharacterization (materials science)OpticsSurface-extended X-ray absorption fine structure0103 physical sciences[PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci][PHYS.COND]Physics [physics]/Condensed Matter [cond-mat]010306 general physics0210 nano-technologybusinessSingle crystalComputingMilieux_MISCELLANEOUSBeam (structure)High Pressure Research
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Optimization of Passive Constrained Layer Damping (Pcld) Treatments for Vibration Reduction

2015

An efficient method to reduce the frequency averaged transverse vibration level of aplate by optimizing the position of attached passive constrained layer damping PCLD is presented.This method uses a multilayer anisotropic plate model which is an equivalent single layer platemodel (ESL) where transverse shear stresses and displacements are continuous at each layer’sinterfaces. Hence, for a laminate composed of an arbitrary number of layers, all the quantities arerelated to those of the first layer. The optimization process is based on the use of the ESL platemodel combined with the genetic algorithm (GA) and Latin Hypercube Sampling (LHS) algorithmimplemented in a Rayleigh-Ritz resolution p…

[SPI]Engineering Sciences [physics][SPI] Engineering Sciences [physics]equivalent single layer plate modelplategenetic algorithmRayleigh-Ritzvibrationpassive constrained layer dampingComputingMilieux_MISCELLANEOUS
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Switch in Relative Stability between cis and trans 2-Butene on Pt(111) as a Function of Experimental Conditions: A Density Functional Theory Study

2018

International audience; The adsorption of cis and trans 2-butenes on Pt(111) has been studied as a function of hydrogen coverage OH by means of calculations based on density functional theory (DFT) with the inclusion of dispersion forces. All hydrogen coverages have been considered, from 0 to 1.00 monolayer (ML). For each case, the di-sigma and pi adsorption geometries of the olefins have been compared at a surface coverage of theta(C4H8) = 0.11 ML. Calculations of the Gibbs free energies of these systems have identified the most stable 2-butene isomer (cis or trans) as a function of coverage, temperature, and pressure. In particular, focus was placed on two sets of conditions, namely, one …

ab-initioMaterials scienceHydrogenmolecular-dynamicschemistry.chemical_element010402 general chemistryenergy recoil scattering7. Clean energy01 natural sciencesDFTCatalysischemistry.chemical_compoundsymbols.namesakecis-trans isomerizationAdsorptionPt(111)Monolayersingle-crystal surfaces[CHIM]Chemical Sciences[PHYS]Physics [physics]1st-principles calculationsethylene hydrogenation010405 organic chemistrymetal-surfacesheterogeneous catalystsGeneral ChemistryAtmospheric temperature range2-Butenefree energyhydrogenation catalysisCis trans isomerization0104 chemical sciencesGibbs free energyH coveragechemistry13. Climate actionadsorptionsymbolsPhysical chemistryDensity functional theory2-butenesolid-surfacestemperature diagram
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Coumarin-Phosphine-Based Smart Probes for Tracking Biologically Relevant Metal Complexes: From Theoretical to Biological Investigations

2016

International audience; Ten metal-based complexes and associated ligands have been synthesized and characterized. One of the metal ligands is a coumarin-phosphine derivative, which displays tunable fluorescence properties. The fluorescence is quenched in the case of the free ligand and ruthenium and osmium complexes, whereas it is strong for the gold complexes and phosphonium derivatives. These trends were rationalized by theoretical calculations, which revealed non-radiative channels involving a dark state for the free ligands that is lower in energy than the emissive state and is responsible for the quenching of fluorescence. For the Ru-II and Os-II complexes, other non-radiative channels…

ab-initiotheranosticschemistry.chemical_element010402 general chemistryPhotochemistry01 natural sciences[ CHIM ] Chemical SciencesQuantitative Biology::Cell BehaviorBioinorganic chemistryInorganic Chemistrychemistry.chemical_compound[CHIM]Chemical SciencesOsmiumSinglet statePhosphoniumtherapyAntitumor agents010405 organic chemistryChemistryLigandFluorescence0104 chemical sciencesRutheniumP ligandsagentsTheranostic agentsExcited stateFluorescent probesporphyrinPhosphine
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Displaying morally responsible motherhood : lone mothers accounting for work during non-standard hours

2020

This study examined how lone mothers rationalise their work during non-standard hours (e.g., evenings and weekends), which they perceive as problematic in terms of child wellbeing, and thereby as violating the culturally shared moral order of ‘good’ motherhood. The data comprise interviews with 16 Finnish lone mothers, analysed as accounts, with a special focus on their linguistic features. The mothers displayed morally responsible motherhood through: (1) excusing work during non-standard hours as an external demand; (2) appealing to an inability to act according to good mothering ideals; (3) using adaptive strategies to protect child wellbeing; and (4) challenging the idea of risk. Our fin…

accounts analysisSociology and Political Science05 social sciencesmotherhoodSingle mothersepätyypillinen työstigmatyksinhuoltajatsingle mothers050902 family studies050903 gender studiesstigmaMoral responsibility0509 other social sciencesäitiysPsychologySocial psychologynon-standard work
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Runs of homozygosity in the Italian goat breeds: impact of management practices in low-input systems

2021

Abstract Background Climate and farming systems, several of which are considered as low-input agricultural systems, vary between goat populations from Northern and Southern Italy and have led to different management practices. These processes have impacted genome shaping in terms of inbreeding and regions under selection and resulted in differences between the northern and southern populations. Both inbreeding and signatures of selection can be pinpointed by the analysis of runs of homozygosity (ROH), which provides useful information to assist the management of this species in different rural areas. Results We analyzed the ROH distribution and inbreeding (FROH) in 902 goats from the Italia…

adaptation; body size; climate change; ecological impact; farming system; goat; inbreeding; management practiceClimateecological impactadaptationQH426-470Runs of homozygosityPolymorphism Single NucleotideSF1-1100GeneticsAnimalsfarming systemsInbreedingPolymorphismEcology Evolution Behavior and SystematicsbiodiversityGenomeSettore AGR/17 - ZOOTECNICA GENERALE E MIGLIORAMENTO GENETICOlocal breedsAnimalGoatsROHHomozygoteGeneral MedicineSingle NucleotideAnimal cultureclimate changeAnimals; Genome; Homozygote; Inbreeding; Goats; Polymorphism Single Nucleotidelocal breeds biodiversity SNPs inbreedingGoatfarming systemRuns of homozygosity ROH Goat signatures of selection low-input system Climate farming systemsAnimal Science and Zoologybody sizeGoat signatures of selectionlow-input systemmanagement practiceResearch ArticleSNPs
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Simulations on the mechanism of CNT bundle growth upon smooth and nanostructured Ni as well as θ-Al2O3 catalysts

2011

Abstract In the current study, we have performed ab initio DFT calculations on the gradually growing 2D periodic models of capped single-wall carbon nanotubes (SW CNTs) upon their perpendicular junctions with the Ni(111) substrate, in order to understand the peculiarities of the initial stage of their growth on either smooth or nanostructured catalytic particles. Appearance of the adsorbed carbon atoms upon the substrate follows from the dissociation of CVD hydrocarbon molecules, e.g., CH4: (CH4)ads → (CH)ads+3Hads and (CH)ads → Cads+Hads. (Since the effective growth of CNTs upon Ni nanoparticles occur inside the nanopores of amorphous alumina, we have also simulated analogous surface react…

adsorption and dissociation of ch4Materials scienceQC1-999General Physics and AstronomyNanoparticleNanotechnology02 engineering and technologyCarbon nanotubeflat and nanostructured surfaces of ni and θ-al2o3 catalystsarcmchair and zigzag-type chiralities01 natural sciencesdft calculationsDissociation (chemistry)Catalysislaw.inventionNanoclusterslaw0103 physical sciencesMoleculemechanism of cnt growth010306 general physicsbundles of single-wall cntsPhysics021001 nanoscience & nanotechnologyAmorphous solidChemical bondChemical engineeringcnt-ni junction0210 nano-technologyCentral European Journal of Physics
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