Search results for "Single"

showing 10 items of 4920 documents

Low back pain and other overuse injuries in a group of Japanese triathletes.

1996

OBJECTIVE: To document the incidence of low back pain and other overuse injuries in a group of triathletes, and to investigate any associations with various physical and triathlon related factors. METHODS: By means of a questionnaire, the physical characteristics, training habits, and the incidences of overuse injuries of 92 Japanese triathletes (70 males, 22 females) were documented. Student's t and chi 2 tests were used to determine the significance of any associations with injury incidence, as well as differences between subjects experiencing or not experiencing low back pain in the previous year. RESULTS: Low back pain was experienced by 32% of subjects in the previous year. The majorit…

Adultmedicine.medical_specialtyCumulative Trauma DisordersStrength trainingTraining timePilot ProjectsPhysical Therapy Sports Therapy and RehabilitationPhysical medicine and rehabilitationJapanSingle siteSurveys and QuestionnairesmedicineHumansAerobic exerciseOrthopedics and Sports MedicineRisk factorbusiness.industryIncidenceIncidence (epidemiology)General MedicineTrunkLow back painAthletic InjuriesPhysical therapymedicine.symptombusinessLow Back Painhuman activitiesResearch ArticleBritish Journal of Sports Medicine
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SPECT Bone scintigraphy of benign and malignant lesions of the spine

1989

70 patients were examined with planar and SPECT bone scintigraphy. SPECT proved to be superior over planar bone scanning for imaging of traumatic, inflammatory, and malignant bone lesions. SPECT provides three-dimensional information and, therefore, delineates the exact location and extension of lesions. It also has a higher sensitivity than planar bone scintigraphy. The three-dimensional bone scan generates complementary diagnostic information which often facilitates an adequate therapy protocol.

Adultmedicine.medical_specialtyDiagnostic informationHumansMedicineRachisTomography Emission-Computed Single-PhotonSpinal Neoplasmsmedicine.diagnostic_testbusiness.industryGeneral MedicineSpineVertebraBone scanningmedicine.anatomical_structureBone scintigraphyBone lesionPositron emission tomographyFemaleSpinal DiseasesSurgeryNeurology (clinical)NeurosurgeryRadiologybusinessNuclear medicineNeurosurgical Review
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Surgical outcomes of diaphragmatic resection during cytoreductive surgery for advanced gynecological ovarian neoplasia: A randomized single center cl…

2022

Introduction: Ovarian cancer (OC) represent nearly 4% of gynecologic malignancies and it is often diagnosed at advanced stage. Diaphragmatic surgery, a fundamental step of advanced stage ovarian cancer (ASOC) debulking surgery, is associated with a high post-operative complication incidence, which is supposedly reduced with thoracostomy tube placement. We assessed the role of intra-operative thoracostomy tube placement, as a prevention measure for post-operative complications, after diaphragmatic resection. Methods: This was a single center prospective randomized trial. Ovarian cancer patients, who underwent mono-lateral diaphragmatic resection, were randomized 1:1 into two arms. Arm A incl…

Adultmedicine.medical_specialtyDiaphragmatic surgeryPleural effusionmedicine.medical_treatmentDiaphragmatic resectionDiaphragmDiaphragmatic breathingThoracentesisCarcinoma Ovarian EpithelialThoracostomySingle CenterPostoperative ComplicationsOvarian cancermedicineHumansAgedOvarian NeoplasmsIntraoperative CareCytoreduction Surgical ProcedureThoracostomy tubebusiness.industryOvarian NeoplasmObstetrics and GynecologyPneumothoraxCytoreduction Surgical ProceduresThoracostomy...Middle Agedmedicine.diseaseDebulkingThoracostomySurgeryPleural EffusionSettore MED/40 - GINECOLOGIA E OSTETRICIALogistic ModelsOncologyPneumothoraxChest TubesFemaleComplicationbusinessGynecologic oncology
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Real-world data confirm the effectiveness of caplacizumab in acquired thrombotic thrombocytopenic purpura

2020

Abstract Acquired thrombotic thrombocytopenic purpura (aTTP) is a rare but life-threatening condition. In 2018, the nanobody caplacizumab was approved for the treatment of adults experiencing an acute episode of aTTP, in conjunction with plasma exchange (PEX) and immunosuppression for a minimum of 30 days after stopping daily PEX. We performed a retrospective, observational analysis on the use of caplacizumab in 60 patients from 29 medical centers in Germany during acute disease management. Caplacizumab led to a rapid normalization of the platelet count (median, 3 days; mean 3.78 days). One patient died after late treatment initiation due to aTTP-associated complications. In 2 patients with…

Adultmedicine.medical_specialtyExacerbationmedicine.medical_treatmentThrombotic thrombocytopenic purpuraMedizin030204 cardiovascular system & hematology03 medical and health sciences0302 clinical medicineFibrinolytic AgentsInternal medicinemedicineHumansRetrospective StudiesAcquired Thrombotic Thrombocytopenic PurpuraPurpura Thrombotic Thrombocytopenicbusiness.industryImmunosuppressionRetrospective cohort studyHematologySingle-Domain Antibodiesmedicine.diseasePurpuraDisease PresentationCardiovascular and Metabolic Diseases030220 oncology & carcinogenesisCaplacizumabmedicine.symptombusiness
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Tyrosine hydroxylase Val-81-Met polymorphism associated with early-onset alcoholism

2005

The present study examined the association of the Tyrosine hydroxylase Val-81-Met polymorphism with alcohol dependence. One hundred and fifty-nine patients in a psychiatric unit with alcohol dependence were genotyped as well as 92 healthy volunteers. The Val allele was more frequent in patients with alcohol dependence (69.5%) than in controls (62.5%). This effect was largely due to the association with early-onset alcoholism (77.8%), whereas no difference was noted between late-onset patients and controls. Our results suggest a role for tyrosine hydroxylase in early-onset alcoholism.

Adultmedicine.medical_specialtyGenotypeTyrosine 3-MonooxygenaseMutation MissensePolymerase Chain ReactionPolymorphism Single Nucleotidechemistry.chemical_compoundMethionineReference ValuesInternal medicineGenotypeGeneticsHumansMedicineMissense mutationAge of OnsetAlleleBiological PsychiatryGenetics (clinical)DNA PrimersEarly onsetMethionineBase SequenceTyrosine hydroxylasebusiness.industryAlcohol dependenceValineAlcoholismPsychiatry and Mental healthEndocrinologychemistryAge of onsetbusinessPolymorphism Restriction Fragment LengthPsychiatric Genetics
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A European Study of the Performance and Safety of MINIject in Patients With Medically Uncontrolled Open-angle Glaucoma (STAR-II)

2020

Precis In this European study (STAR-II), MINIject, a novel, ab-interno, supraciliary MIGS device, effectively lowered intraocular pressure (IOP) and the need for IOP-lowering medications in patients with primary open-angle glaucoma. Purpose To evaluate the safety and performance of a minimally invasive supraciliary glaucoma drainage device (MINIject DO627, iSTAR Medical SA, Wavre, Belgium) for surgical treatment of primary open angle glaucoma in patients refractory to topical hypotensive medications. Methods In a prospective, interventional, single-arm, multi-center, European study (STAR-II), MINIject was successfully implanted in a standalone procedure in 29 of 31 patients in 8 sites in 3 …

Adultmedicine.medical_specialtyIntraocular pressureTime Factorsgenetic structuresOpen angle glaucomaGlaucomaOriginal StudiesProsthesis ImplantationTonometry Ocular03 medical and health sciences0302 clinical medicineRefractoryOphthalmologymedicineClinical endpointHumansMinimally Invasive Surgical ProceduresSingle-Blind MethodIn patientEuropean UnionProspective StudiesGlaucoma Drainage ImplantsAdverse effectAntihypertensive AgentsIntraocular PressureAgedAged 80 and overEquipment Safetybusiness.industryIOPMIGSMiddle Agedmedicine.diseaseGlaucoma drainage deviceMINIjecteye diseasesOphthalmologyglaucomaTreatment Outcome030221 ophthalmology & optometryFemalesupraciliarysense organsbusinessGlaucoma Open-Angle030217 neurology & neurosurgeryJournal of Glaucoma
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Clinical evaluation of an Er:YAG laser combined with scaling and root planing for non-surgical periodontal treatment

2003

Objectifs: le but de cette etude clinique controlee etait de comparer les traitements de maladie parodontale avancee par une association de laser Er:YAG (KEY II®, KaVo, Germany) et de detartrage et surfacage radiculaire manuels (SRP) avec le laser seul. Materiel & Methodes: 20 patients sains presentant des destructions parodontales moderees a avancees furent traites au hasard en bouche divisee par une association de laser Er:YAG et de detartrage et surfacage radiculaire manuels (SRP) (test) et le laser seul (controle). L'energie utilisee en reglage pour le laser etait de 160 mJ/pulsation a un taux de repetition de 10 Hz. Prealablement au traitement, et 3, 6 etl2 mois apres, les parametres s…

Adultmedicine.medical_specialtyPeriodontal treatmentMatched-Pair AnalysisTreatment outcomeDental PlaqueStatistics NonparametricRoot PlaningScaling and root planingPeriodontal Attachment LossHumansPeriodontal PocketMedicineGingival RecessionSingle-Blind MethodYttriumProspective StudiesPeriodontal DiseasesGynecologyBacteriabusiness.industryDental Plaque IndexFollow up studiesRoot planingMiddle AgedSurgeryTreatment OutcomeSpirochaetalesProspective clinical studyDental ScalingPeriodonticsAluminum SilicatesLaser TherapyPeriodontal IndexbusinessClinical evaluationEr:YAG laserErbiumFollow-Up StudiesJournal of Clinical Periodontology
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Preterm birth: seven-year retrospective study in a single centre population

2019

Preterm birth is a health and social problem, considered the leading cause of neonatal mortality worldwide. It is associated with higher rates of neurodevelopmental morbidity, sensorineural impairments and other complications. The aim of the study was to describe the incidence and the major risk factors associated with preterm birth. METHODS: We performed a single center, observational and retrospective Cohort study in the Division of Obstetrics and Gynaecology, University Hospital "G. Martino", Messina. Clinical records of all pregnant women who delivered from 1st January 2010 to 31 of December 2016 were collected. RESULTS: In the 7 years considered, a total of 7954 pregnant women were inc…

Adultmedicine.medical_specialtyPopulationOligohydramniosTrans-vaginal cervical screeningSingle CenterCohort Studies03 medical and health sciences0302 clinical medicineThinnessObstetrics and gynaecologyPregnancy030225 pediatricsmedicineHumansObesity030212 general & internal medicineeducationRetrospective StudiesBirth; Cervical length Prematurity Risk factors Trans-vaginal cervical screening Pediatrics Perinatology and Child Healtheducation.field_of_studyMarital Statusbusiness.industryObstetricsResearchIncidence (epidemiology)Infant Newbornlcsh:RJ1-570Retrospective cohort studylcsh:PediatricsGeneral Medicinemedicine.diseasePregnancy ComplicationsItalyRisk factorsCervical Length MeasurementCohortBirthPremature BirthFemaleRisk factorUnderweightmedicine.symptombusinessPrematurityCervical lengthItalian Journal of Pediatrics
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How to demonstrate that eSET does not compromise the likelihood of having a baby?

2009

BACKGROUND: In several randomized studies, elective single embryo transfer (eSET) has proven its effectiveness in reducing twin pregnancy rates while obtaining acceptable overall pregnancy rates. However, there is no outcome measurement consensus to evaluate the effectiveness of eSET versus double-embryo transfer (DET). METHODS: This study evaluated whether or not adopting an eSET strategy instead of a DET strategy lowers the probability of having at least one live-born infant in good prognosis couples. Seven hundred and twenty-six couples were divided into two groups. The retrospective arm of the study was undertaken on the first group of couples (n = 483, DET group) and the prospective ar…

Adultmedicine.medical_specialtyPregnancy Ratemedicine.medical_treatmentStatistics as TopicSingle Embryo TransferMultiple Birth OffspringIntracytoplasmic sperm injectionClinical ProtocolsPregnancyOutcome Assessment Health CaremedicineSingle Embryo TransferHumansPregnancyObstetricsbusiness.industryRehabilitationObstetrics and Gynecologymedicine.diseaseEmbryo TransferOutcome (probability)Embryo transferPregnancy rateReproductive MedicineInfertilityObservational studyFemalebusinessLive birthHuman reproduction (Oxford, England)
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Elective single versus double embryo transfer: live birth outcome and patient acceptance in a prospective randomised trial

2013

The purpose of this study was to determine which strategy of embryo transfer has a better trade-off in live birth delivery rate versus multiple pregnancy considering patient acceptance: elective single embryo transfer (eSET) or elective double embryo transfer (eDET). In all, 199 women <38 years of age undergoing their first IVF treatment in a private centre were included in a prospective open-label randomised controlled trial. Patients were randomised into four groups: (1) eSET on Day 3; (2) eSET on Day 5; (3) eDET on Day 3; and (4) eDET on Day 5. Per patient, main analysis included acceptance of assigned group, as well as multiple and live birth delivery rates of the fresh cycle. Second…

Adultmedicine.medical_specialtyPregnancy Ratemultiple birth ratemultiple pregnancyFertilization in VitroReproductive technologyBiologyBirth ratelaw.inventionEndocrinologyRandomized controlled trialPregnancylawSingle Embryo TransferGeneticsmedicineHumansProspective Studiesdelivery rateBirth RateMolecular BiologyPregnancyObstetricsPregnancy OutcomeEmbryo culturePatient Acceptance of Health CareEmbryo Transfermedicine.diseaseEmbryo transferPregnancy rateTreatment OutcomeReproductive MedicineFemaleAnimal Science and ZoologyPregnancy MultipleLive birthLive BirthMaternal AgeDevelopmental BiologyBiotechnologyReproduction, Fertility and Development
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