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RESEARCH PRODUCT
Preterm birth: seven-year retrospective study in a single centre population
Ilaria FazzolariEloisa GittoGloria CalagnaGiovanni CorselloDonatella AmadoreRaffaele FalsaperlaRoberta GraneseRoberta GrassoOnofrio TrioloGabriella D'angelosubject
Adultmedicine.medical_specialtyPopulationOligohydramniosTrans-vaginal cervical screeningSingle CenterCohort Studies03 medical and health sciences0302 clinical medicineThinnessObstetrics and gynaecologyPregnancy030225 pediatricsmedicineHumansObesity030212 general & internal medicineeducationRetrospective StudiesBirth; Cervical length Prematurity Risk factors Trans-vaginal cervical screening Pediatrics Perinatology and Child Healtheducation.field_of_studyMarital Statusbusiness.industryObstetricsResearchIncidence (epidemiology)Infant Newbornlcsh:RJ1-570Retrospective cohort studylcsh:PediatricsGeneral Medicinemedicine.diseasePregnancy ComplicationsItalyRisk factorsCervical Length MeasurementCohortBirthPremature BirthFemaleRisk factorUnderweightmedicine.symptombusinessPrematurityCervical lengthdescription
Preterm birth is a health and social problem, considered the leading cause of neonatal mortality worldwide. It is associated with higher rates of neurodevelopmental morbidity, sensorineural impairments and other complications. The aim of the study was to describe the incidence and the major risk factors associated with preterm birth. METHODS: We performed a single center, observational and retrospective Cohort study in the Division of Obstetrics and Gynaecology, University Hospital "G. Martino", Messina. Clinical records of all pregnant women who delivered from 1st January 2010 to 31 of December 2016 were collected. RESULTS: In the 7 years considered, a total of 7954 pregnant women were included in our study. The majority of all preterm births were due to infants born late preterm (71.83%), 26.45% were due to preterm and 1.72% to extremely preterm. The preterm cohort had a higher proportion of history of preterm delivery (p < 0.0001), and unmarried (p = 0.003) and underweight or obese patients (p < 0.0001). In addition, prematurity was associated with presence of uterine anomalies (p < 0.0001), vaginal/urinary infections (p = 0.02), poli/oligohydramnios (p < 0.0001), maternal diabetes (p = 0.004), hypertension (p < 0.0001), short cervical length (p < 0.0001). CONCLUSIONS: We suggest prompt identification of all risk factors associated with preterm birth to apply immediate and appropriate specific interventions.
year | journal | country | edition | language |
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2019-01-01 | Italian Journal of Pediatrics |