Search results for "TG"
showing 10 items of 2275 documents
Low-Power, Subthreshold Reference Circuits for the Space Environment : Evaluated with -rays, X-rays, Protons and Heavy Ions
2019
The radiation tolerance of subthreshold reference circuits for space microelectronics is presented. The assessment is supported by measured results of total ionization dose and single event transient radiation-induced effects under &gamma
Training Secondary Education Teachers through the Prism of Sustainability: The Case of the Universitat de València
2018
Designing the training of future teachers through holistic and interdisciplinary visions is vital to developing coherent contents, epistemologies, and methodologies that put Education for Sustainability into action. The research presented here analyzes the teaching guides from the curriculum for the Master&rsquo
Automatic mass spectra recognition for Ultra High Vacuum systems using multilabel classification
2021
Abstract In Ultra High-Vacuum (UHV) systems it is common to find a mixture of many gases originating from surface outgassing, leaks and permeation that contaminate vacuum chambers and cause issues to reach ultimate pressures. The identification of these contaminants is, in general, done manually by trained technicians from the analysis of mass spectra. This task is time consuming and can lead to misinterpretation or partial understanding of issues. The challenge resides in the rapid identification of these contaminants by using some automatic gas identification technique. This paper explores the automatic and simultaneous identification of 80 molecules, including some of the most commonly p…
Enhancing Disaster Response for Hazardous Materials Using Emerging Technologies: The Role of AI and a Research Agenda
2019
Despite all efforts like the introduction of new training methods and personal protective equipment, the need to reduce the number of First Responders (FRs) fatalities and injuries remains. Reports show that advances in technology have not yet resulted in protecting FRs from injuries, health impacts, and odorless toxic gases effectively. Currently, there are emerging technologies that can be exploited and applied in emergency management settings to improve FRs protection. The aim of this paper is threefold: First, to conduct scenario analysis and situations that currently threat the first responders. Second, to conduct gap analysis concerning the new technology needs in relations to the pro…
Using Inverse Reinforcement Learning with Real Trajectories to Get More Trustworthy Pedestrian Simulations
2020
Reinforcement learning is one of the most promising machine learning techniques to get intelligent behaviors for embodied agents in simulations. The output of the classic Temporal Difference family of Reinforcement Learning algorithms adopts the form of a value function expressed as a numeric table or a function approximator. The learned behavior is then derived using a greedy policy with respect to this value function. Nevertheless, sometimes the learned policy does not meet expectations, and the task of authoring is difficult and unsafe because the modification of one value or parameter in the learned value function has unpredictable consequences in the space of the policies it represents…
GOBERNANZA DEL AGUA Y TERRITORIOS HIDROSOCIALES: DEL ANÁLISIS INSTITUCIONAL A LA ECOLOGÍA POLÍTICA
2018
[ES] En las últimas décadas han surgido diversos enfoques para dar respuesta a los desafíos que plantea la gestión del agua. Este artículo presenta, de manera introductoria, las principales aproximaciones teóricas desde las cuales se está analizando en la actualidad el uso y la gobernanza del agua: las corrientes neoinstitucionalistas, la teoría de los recursos comunes y la perspectiva del empoderamiento que se relaciona con la ecología política. La descripción de estos enfoques sirve para contextualizar las distintas aportaciones que se presentan en este monográfico sobre el estudio de los territorios hidrosociales, cuyos principales resultados se exponen sucintamente.
Arrangement of myofibroblastic and smooth muscle-like cells in superficial peritoneal endometriosis and a possible role of transforming growth factor…
2018
Purpose: Superficial peritoneal endometriotic (pEM) lesions are composed of endometrial glands and stroma, in addition to a third component—myofibroblasts and smooth muscles (SM)-like cells. The latter develops secondary to a metaplasia. In this study, we characterised the third component cells in pEM according to differentiation markers in different micro-compartments. Furthermore, a possible effect of TGFβ1 on myofibroblastic metaplasia in endometriotic epithelial cells was studied. Methods: Seventy-six premenopausal patients were included. Peritoneal biopsies were excised from EM patients (n = 23), unaffected peritoneum (peritoneum from EM patients but without EM components, n = 5/23) an…
IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss
2021
This article belongs to the Collection Insulin-Like Growth Factors in Development, Cancers and Aging.
Adult rat myelin enhances axonal outgrowth from neural stem cells.
2018
Axon regeneration after spinal cord injury (SCI) is attenuated by growth inhibitory molecules associated with myelin. We report that rat myelin stimulated the growth of axons emerging from rat neural progenitor cells (NPCs) transplanted into sites of SCI in adult rat recipients. When plated on a myelin substrate, neurite outgrowth from rat NPCs and from human induced pluripotent stem cell (iPSC)-derived neural stem cells (NSCs) was enhanced threefold. In vivo, rat NPCs and human iPSC-derived NSCs extended greater numbers of axons through adult central nervous system white matter than through gray matter and preferentially associated with rat host myelin. Mechanistic investigations excluded …
Heat shock protein (Hsp) regulation by muscarinic acetylcholine receptor (mAChR) activation in the rat hippocampus.
2018
The cholinergic system plays a crucial role in modulating in the central nervous system physiological responses such as neurogenesis, neuronal differentiation, synaptic plasticity, and neuroprotection. In a recent study, we showed that Oxotremorine-M, a non-selective muscarinic acetylcholine receptor agonist, is able to transactivate the fibroblast growth factor receptor and to produce a significant increase in the hippocampal primary neurite outgrowth. In the present study we aimed to explore in the rat hippocampus the possible effect of acute or chronic treatment with Oxotremorine-M on some heat shock proteins (Hsp60, Hsp70, Hsp90) and on activation of related transcription factor heat sh…