Search results for "TRIP"
showing 10 items of 2134 documents
Análisis molecular de la valoración del intervalo de tiempo óptimo entre la administración de acetato de triptorelina y la punción folicular en los t…
2023
Los fármacos análogos de la GnRH y la hCG han demostrado ser igualmente eficaces en la activación de la cascada de intermediarios de la maduración final ovocitaria que ocurre tras el estímulo ovulatorio. Sin embargo, su mecanismo de acción y por tanto los perfiles hormonales hallados tras el estímulo de los dos fármacos son muy diferentes. El tiempo más adecuado para programar la recolección ovocitaria tras la administración de acetato de triptorelina podría no ser 36 horas como ampliamente se ha pautado en los tratamientos de FIV con hCG. Este intervalo de tiempo es sumamente importante para obtener la mayor proporción posible de ovocitos MII porque procesos como el inicio de la luteinizac…
Assessment of microplastics and other contaminants in marine vertebrates from the Western Mediterranean Sea
2023
Mediterranean marine biodiversity is under threat by pollution. For this reason, the main objective of this thesis was to analyse the presence of pollutants of concern in Mediterranean marine species. These studies are located in the Valencian Community (Spain), where we find loggerhead turtles, striped dolphins, and jewel lanternfish. Hence, we: 1. Analysed pesticides, heavy metals and phthalates in tissues of loggerhead turtles. 2. Studied microdebris present in beaches that are sporadically used as nesting grounds by loggerhead turtles. 3. Analysed striped dolphins# exposure to microplastics. 4. Quantified jewel lanternfish exposure to microplastics and tested their role as bioindicators…
Aneiploīdija, dzimumhromosomu izmaiņas un mejotisko gēnu ekspresija vīriešu ļaundabīgajos audzējos: Iespējamā mejotiskā izcelsme
2017
Novērots, ka vairākos vēža tipos DNS sadalījums para-triploīdajā diapazonā (ap 69 hromosomām) ir bieži saistīts ar lielāku ļaundabīgumu, paaugstinātu rezistenci pret ķīmijterapiju un nelabvēlīgu prognozi pacientam. Šobrīd vadošā teorija uzskata, ka triploīdās vēža šūnas veidojas no tetraploīdajām nejaušo anomālo mitožu sērijas rezultātā. Tomēr jaunākie novērojumi liecina, ka triploīdijas rašanās var nebūt pilnīgi nejauša un ka tā varētu būt iesaistīta vēža attīstības svarīgākajās stadijās. Sakarā ar jaunākajiem novērojumiem par to, kādu lomu spēlē vēža cilmes šūnas audzēju pašatjaunošanās procesā, zinātnieki sāka atkārtoti pievērsties 19. gadsimta teorijai, kura uzskata, ka vēža šūnu evolūc…
Correction to: A practical algorithmic approach to mature aggressive B cell lymphoma diagnosis in the double/triple hit era: selecting cases, matchin…
2019
The Acknowledgments section of this article has been corrected to 1) correct the formatting of Arianna Di Napoli's name to 'DiNapoli A', and 2) to include the name of Alessandro Corsi which was omitted in the original Lazio Group of Haematopathologist list. No further changes have been made to the publication. The corrected Acknowledgments section is as follows:.
Supervisor leadership style, employee regulatory focus, and leadership performance: A perspectivism approach
2019
[EN] Drawing on regulatory focus theory, this research proposes that transformational leadership performance depends on followers' circumstances. The analysis of 125 people from two Spanish service firms reveals that, apart from transformational leadership, the presence of academic education, intrinsic job satisfaction and high customer contact, and the absence of family responsibilities, are core conditions for the presence of high leadership performance. The first contribution of this study is the direct inference of follower's regulatory focus from the observation of individuals' circumstances. The second contribution is that leaders should consider followers' circumstances to adopt a su…
Implications of Value Co-Creation in Green Hotels: The Moderating Effect of Trip Purpose and Generational Cohort
2020
Recently, great interest in value co-creation has been revealed among both academics and practitioners in the hotel sector. However, few studies are analyzing the consequences of co-creation behavior from the customer perspective in &ldquo
Multi-destination trips: A survey on incoming zourism in Sicily
2012
Many pleasure trips are often characterized by the visit of more than a single destination. Despite the topic is well documented in literature, the empirical studies are limited to a few pioneering studies. This lack may be attributable to the failure of tourism organizations to collect data on multi-destination trip behaviors, as it results, for example, from the system of European statistics on tourism (according to the Council Directive 95/57 EC), where no information on the average number of destinations visited within a single trip are provided. This paper aims to analyze the main implications of multi-destination trips both on tourism statistics and in tourism planning, and to describ…
Lithotripsy of Calcified Aortic Valve Leaflets by a Novel Ultrasound Transcatheter-Based Device
2022
The increasing incidence of calcific aortic valve disease necessitates the elaboration of new strategies to retard the progression of the pathology with an innovative solution. While the increasing diffusion of the transcatheter aortic valve replacements (TAVRs) allows a mini-invasive approach to aortic valve substitution as an alternative to conventional surgical replacement (SAVR) in an always larger patient population, TAVR implantation still has contraindications for young patients. In addition, it is liable to undergo calcification with the consequent necessity of re-intervention with conventional valve surgery or repeated implantation in the so-called TAVR-in-TAVR procedure. Inspired …
Evaluation of a novel monoclonal antibody against tumor-associated MUC1 for diagnosis and prognosis of breast cancer
2019
There is still a great unmet medical need concerning diagnosis and treatment of breast cancer which could be addressed by utilizing specific molecular targets. Tumor-associated MUC1 is expressed on over 90 % of all breast cancer entities and differs strongly from its physiological form on epithelial cells, therefore presenting a unique target for breast cancer diagnosis and antibody-mediated immune therapy. Utilizing an anti-tumor vaccine based on a synthetically prepared glycopeptide, we generated a monoclonal antibody (mAb) GGSK-1/30, selectively recognizing human tumor-associated MUC1. This antibody targets exclusively tumor-associated MUC1 in the absence of any binding to MUC1 on health…
Validation of ATP bioluminescence as a tool to assess antimicrobial effects of mouthrinses in an in vitro subgingival-biofilm model
2012
Objectives. The aim of this investigation was to evaluate whether the adenosine triphosphate (ATP) bioluminescence method is an appropriate tool to assess the efficacy of antiseptic mouthrinses in terms of quantitative reductions of total viable microbial counts in mixed biofilm populations in vitro. Study Design. Three mouthrinses, containing respectively, chlorhexidine and cetylpyridinium chloride (CHX/CPC), essential oils (EO) and amine fluoride/stannous fluoride (AFSF), as well as Phosphate Buffered Saline (PBS) used as control, were tested in an in vitro static biofilm model by ATP bioluminescence and compared to culture method. Biofilms were grown on saliva-coated hydroxyapatite disks…