Search results for "Testing"
showing 10 items of 1769 documents
Modification of human platelet adhesion on biomaterial surfaces by protein preadsorption under static and flow conditions.
2004
Biomaterial-induced thrombosis remains one of the main complications of vascular implant devices. Preadsorbed proteins on the biomaterial/blood interface will modify the adhesion and activation of platelets (PTLs) during the initial contact-phase. Our results clearly show that PTL-adherence on biomaterials is influenced not only by protein preadsorption, but also by flow conditions. The covalent coating of TCPS and glass by phosphorylcholine (PC) induces a significant decrease of PTL adhesion but leads to a slight, but nevertheless significant activation of PTL, which was detected by the induction of P-selectin expression using FACS analysis. Methodologically, the visualization of PTL adhes…
Response of human endothelial cells to oxidative stress on Ti6Al4V alloy.
2007
Titanium and its alloys are amongst the most frequently used materials in bone and dental implantology. The good biocompatibility of titanium(-alloys) is attributed to the formation of a titanium oxide layer on the implant surface. However, implant failures do occur and this appears to be due to titanium corrosion. Thus, cells participating in the wound healing processes around an implanted material, among them endothelial cells, might be subjected to reactive oxygen species (ROS) formed by electrochemical processes during titanium corrosion. Therefore, we studied the response of endothelial cells grown on Ti6Al4V alloy to H(2)O(2) and compared this with the response of endothelial cells gr…
Histological and histomorphometrical analysis of a silica matrix embedded nanocrystalline hydroxyapatite bone substitute using the subcutaneous impla…
2010
The clinical suitability of a bone substitute material is determined by the ability to induce a tissue reaction specific to its composition. The aim of this in vivo study was to analyze the tissue reaction to a silica matrix-embedded, nanocrystalline hydroxyapatite bone substitute. The subcutaneous implantation model in Wistar rats was chosen to assess the effect of silica degradation on the vascularization of the biomaterial and its biodegradation within a time period of 6 months. Already at day 10 after implantation, histomorphometrical analysis showed that the vascularization of the implantation bed reached its peak value compared to all other time points. Both vessel density and vascula…
In-process calibration of a non-destructive testing system used for in-process inspection of multi-pass welding
2020
Abstract In multi-pass welding, there is increasing motivation to move towards in-process defect detection to enable real-time repair; thus avoiding deposition of more layers over a defective weld pass. All defect detection techniques require a consistent and repeatable approach to calibration to ensure that measured defect sizing is accurate. Conventional approaches to calibration employ fixed test blocks with known defect sizes, however, this methodology can lead to incorrect sizing when considering complex geometries, materials with challenging microstructure, and the significant thermal gradients present in materials during the inter-pass inspection period. To circumvent these challenge…
Friction and wear testing of multilayer coatings on carbide substrates for dry machining applications
2002
Abstract The principle aim of this paper is to investigate three wear-protective coatings with multilayer structures, which are frequently used in the cutting tool industry and to assess their frictional behaviour under the test conditions equivalent to those for the cutting of medium carbon steel. A modified pin-on-disc tester was used to conduct experiments in which both the friction coefficient and the linear wear of the tribo-pair were recorded vs. sliding distance. The volumetric wear rate was proposed as a parameter for quantitative comparison of the wear resistance of the tribo-pairs tested. It was found that the principle stage of the specimen wear takes place during the first 200–2…
Fatigue crack initiation and subsequent crack growth in fillet welded steel joints
2019
Abstract The fatigue damage evolution in fillet welded steel joints where cracks are emanating from the weld toe is investigated. Based on existing experimental data for as-welded joints including crack depth measurements of the early crack growth it is proposed to make a distinction between the crack initiation phase and the subsequent crack growth phase. The welded detail in question is an F class detail with plate thickness 25 mm made of medium strength carbon steel. It is found that the crack initiation phase defined at a crack depth of 0.1 mm is close to 25% of the fatigue life even at a relatively high constant stress range of 150 MPa. At lower stress ranges it is concluded that the i…
Induced Modification of Flexural Toughness of Natural Hydraulic Lime Based Mortars by Addition of Giant Reed Fibers
2020
Abstract Nowadays, there is a growing need to reduce the environmental impact generated by the use of inorganic materials for building applications. The aim of this work is to investigate the bio-lime based mortar flexural toughness improvement due to the addition of common reed fibers (Arundo donax L.) in order to evaluate their possible application as ductile eco-compatible prefabricated bricks or laying and joint mortars for masonry. Different sets of specimens were tested by varying the fiber weight content and the fiber length. Moreover, chemical treatments with Linseed Oil and Polyethylene glycol (PEG) were performed to improve the physical and mechanical properties of the fibers as w…
Masonry columns confined with fabric reinforced cementitious matrix (FRCM) systems: A round robin test
2021
Abstract The conservation and the preservation of existing masonry buildings, most of them recognized as cultural heritage, require retrofitting techniques that should reduce the invasiveness and assure reversibility and compatibility with the substrate. In this perspective, the strengthening system should be able to improve the bearing capacity of the structural member and, at the same time, to assure mechanical and material compatibility. The use of Fabric Reinforced Cementitious Matrix (FRCM) composites is now recognized to be suitable for these purposes. Indeed, the inorganic matrix has comparable properties with respect to the existing historical mortars while the fabric has relevant t…
Scaffolds based on hyaluronan crosslinked with a polyaminoacid: Novel candidates for tissue engineering application
2008
New porous scaffolds, with a suitable hydrolytic and enzymatic degradation, useful for tissue engineering applications have been obtained by a carbodiimide mediated reaction between hyaluronan (HA) and a synthetic polymer with a polyaminoacid structure such as α,β-polyaspartylhydrazide (PAHy). Scaffolds with a different molar ratio between PAHy repeating units and HA repeating units have been prepared and characterized from a chemical and physicochemical point of view. Tests of indirect and direct cytotoxicity, cell adhesion, and spreading on these biomaterials have been performed by using murine L929 fibroblasts. The new biomaterials showed a good cell compatibility and ability to allow ce…
Prediction of Ductile Fractures in Metal-Forming Processes: an Approach Based on the Damage Mechanics
1994
The Authors propose a new approach for the prediction of ductile fractures in bulk metal forming processes: the approach is based on a numerical analysis able to take into account damage occurrence and evolution in constitutive equations. The model supplies the distribution of the void volume fraction in the workpiece during the deformation path: consequently, the comparison to a critical value, determined by means of a simple tension test, allows to predict the growth of defects. The proposed approach has been applied to the drawing process: the numerical results have been compared with a set of experimental tests showing a good predictive capability of the model.