Search results for "Teucrium"

showing 10 items of 45 documents

Cardiovascular effects of the methanol and dichloromethanol extracts fromTeucrium flavum L.

1998

The effects on arterial blood pressure and heart rate of the methanol and dichloromethanol extracts from Teucrium flavumL. were analysed in urethane anaesthetized rats. Mean arterial blood pressure was significantly reduced by the i.v. administration of both extracts to normotensive rats. The methanol extract also induced a decrease in the heart rate, while the dichloromethanol extract lacked any effect on this parameter. © 1998 John Wiley & Sons, Ltd.

PharmacologyFolk medicinebiologyTraditional medicinebusiness.industryHemodynamicsPharmacognosybiology.organism_classificationTeucrium flavumTeucriumchemistry.chemical_compoundBlood pressurechemistryHeart rateMedicineMethanolbusinessPhytotherapy Research
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Advances on the chemistry of furano-diterpenoids from Teucrium genus

2005

This paper updates the previous reviews, reporting the results published in the last six years on the chemistry of these diterpenoids.

PharmacologyLamiaceaebiologyStereochemistryChemistryOrganic ChemistryneoclerodanediterpenoidGeneral Medicinefuroclerodanebiology.organism_classificationAnalytical ChemistryTeucriumTeucriumTerpeneGenusBotanyLamiaceae
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Evaluation of the analgesic action of different fractions from the methanol extract of Teucrium buxifolium L

1998

Different fractions (F-2, F-3, F-5) of the methanol extract from Teucrium buxifolium L. have been tested for their analgesic activity in mice. All of them exhibited peripheral analgesic activity except F-3, Fraction F-5 had the strongest effect and was subjected to a second re-extraction. The subfractions obtained (F-5/3 and F-5/8) exhibited a similar activity to that observed with the whole fraction. (C) 1998 John Wiley & Sons, Ltd.

PharmacologyTraditional medicinebiologybusiness.industryAnalgesicanalgesiaFraction (chemistry)Biological activityPharmacognosybiology.organism_classificationlaw.inventionTeucriumchemistry.chemical_compoundAcetic acidacetic acidchemistrylawMedicineMethanolPhytotherapybusinessTeucrium buxifolium L. fractionsPhytotherapy Research
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Evaluation of the analgesic and CNS actions of different fractions from the methanol extract ofTeucrium flavum L.

1998

Different fractions (F.1, F-3, F-5, F-6, F-7, F-8) of the methanol extract from Teucrium flavum L. have been tested for their central nervous system and analgesic activities at a dose of 200 mg/kg. Fractions F-1, F-3 and F-7 showed CNS depressant activity, while fractions F-5, F-6 and F-8 had a slight CNS stimulant action. Fractions F-5, F-6, F-7 and F-8 were responsible for the analgesic activity of the extract.

PharmacologyTraditional medicinebusiness.industryCns depressantCentral nervous systemAnalgesicBiological activityPharmacognosyTeucrium flavumlaw.inventionchemistry.chemical_compoundmedicine.anatomical_structurechemistrylawmedicineMethanolPhytotherapybusinessPhytotherapy Research
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Evaluation of the acute toxicity, analgesic and CNS activities of different species ofTeucrium genus

1995

Methanol and dichloromethanol extracts of the leaves and stems of four Teucrium species (T. cartaginenses, T. flavum, T. pumillum and T. buxifolium) have been tested for their toxicity, analgesic and central depressor effects. The intraperitoneal administration of the different extracts showed a CNS depressant activity in mice, but they lacked anticonvulsive effects. When tested for analgesic activity none of the extracts increased the threshold of pain thermal stimulus. However, the methanol and dichloromethanol extracts of T. cartaginenses and T. buxifolium species showed a significant analgesic effect in models of pain induced by chemical or mechanical stimulation.

PharmacologybiologyChemistryTEUCRIUM CARTAGINENSES EXTRACTSTEUCRIUM FLAVUM EXTRACTSAnalgesicCentral nervous systemTEUCRIUM BUXIFOLIUM EXTRACTSStimulationBiological activityEFFECTS ON CNSPharmacologybiology.organism_classificationAcute toxicityTeucriumANALGESIAmedicine.anatomical_structureThreshold of painToxicitymedicineTEUCRIUM PUMILLUM EXTRACTSPhytotherapy Research
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Effects on arterial blood pressure of the methanol extracts from differentTeucriumspecies

1997

Methanol extracts of the leaves and stems of two Teucrium species (T. pumillum L. and T. buxifolium L.) have been tested for their effects on resting arterial blood pressure. Both T. pumillum L. and T. buxifolium L. extracts reduced mean arterial blood pressure in a dose dependent manner when administered i.v. to urethane anaesthetized normotensive rats. © 1997 John Wiley & Sons, Ltd.

PharmacologybiologyTraditional medicinebusiness.industryHypotensive drugDose dependencePharmacognosybiology.organism_classificationTeucriumchemistry.chemical_compoundBlood pressurechemistryTeucrium pumilumMedicineLamiaceaeMethanolbusinessPhytotherapy Research
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Neoclerodane Diterpenoids from Teucrium maghrebinum

2000

Eight neoclerodane diterpenoids were identified in the extract of the aerial parts of Teucrium maghrebinum. Three of these, 12-epi-teucjaponin A (1), 12-epi-montanin D (2), and 12-epi-montanin B (3), are new natural products, whereas five, teucjaponin A, montanin D, 19-deacetylteuscorodol, teusalvin C (4), and montanin B, are already known. These eight compounds form four pairs of epimers at carbon C-12.

Pharmacologychemistry.chemical_classificationFolk medicineLamiaceaeMagnetic Resonance SpectroscopyMolecular StructurebiologyStereochemistryOrganic ChemistryPharmaceutical SciencePharmacognosybiology.organism_classificationMass SpectrometryTerpenoidAnalytical ChemistryTeucriumchemistry.chemical_compoundComplementary and alternative medicinechemistryDrug DiscoveryMolecular MedicineEpimerDiterpenesDiterpeneLactoneJournal of Natural Products
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Analysis of Essential Oil from Teucrium maghrebinum Greuter et Burdet Growing Wild in Algeria

2009

The chemical composition of the essential oil obtained from aerial parts of Teucrium maghrebinum growing wild in Algeria was analyzed by GC and GC-MS. Among the 66 identified compounds, δ-cadinene (12.7%), germacrene D (11.4%), γ-cadinene (9.5%) and 4-vinyl guaiacol (4.0%) were the most abundant. The oil is strongly characterized by the presence of sesquiterpenes (61.5%), particularly hydrocarbon sesquiterpenes (49.6%).

Pharmacologychemistry.chemical_classificationbiologyChemistryPlant ScienceGeneral Medicinebiology.organism_classificationlaw.inventionTeucriumchemistry.chemical_compoundHydrocarbonComplementary and alternative medicinelawDrug DiscoveryBotanyLamiaceaeGuaiacolGas chromatography–mass spectrometryChemical compositionEssential oilGermacrene DNatural Product Communications
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Neoclerodane Diterpenoids from Teucrium massiliense

1998

A reinvestigation of the diterpene metabolites of Teucrium massiliense L. allowed the isolation of four new neoclerodane derivatives, teumassilenins A-D, together with all the diterpenoids previously reported as constituents of this plant. The structures of the new compounds (1-4) were established by chemical and spectroscopic means. A plausible biogenetic relationship between several of these substances is briefly discussed, and some unpublished physical and spectroscopic data of the previously known diterpenoid teumassin (5) are now reported.

Pharmacologychemistry.chemical_compoundComplementary and alternative medicineChemistryStereochemistryOrganic ChemistryDrug DiscoveryPharmaceutical ScienceMolecular MedicineTeucrium massilienseDiterpeneTerpenoidAnalytical ChemistryJournal of Natural Products
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Cardiovascular effects of the methanol and dichloromethanol extracts fromTeucrium cartaginenses L.

1998

Methanol and dichloromethanol extracts of the leaves and stems of Teucrium cartaginensesL. have been tested for their effects on resting arterial blood pressure, heart rate and noradrenaline induced hypertension. Both extracts administered i.v. to urethane anaesthetized normotensive rats reduced mean arterial blood pressure and heart valve, while only the dichloromethanol extract prevented noradrenaline induced hypertension. © 1998 John Wiley & Sons, Ltd.

Pharmacologymedicine.medical_specialtybiologyHemodynamicsPharmacologyPharmacognosybiology.organism_classificationSurgeryTeucriumNorepinephrine (medication)Blood pressuremedicine.anatomical_structureHeart ratemedicineCatecholamineHeart valvemedicine.drugPhytotherapy Research
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