Search results for "Tosyl"

showing 10 items of 89 documents

Competitive NH···Ru/Fe Hydrogen Bonding in Ferrocenyl Ruthenocenyl Tosyl Hydrazone

2016

A strong nonclassical NH···Fe intramolecular hydrogen bond (IHB) is present in the literature-known diferrocenyl tosyl hydrazone (1). Here, we confirm by NMR and IR spectroscopy as well as by XRD methods that an analogous NH···Ru IHB is present in the heavier homologue diruthenocenyl tosyl hydrazone (2). The NH···Ru IHB in 2 is stronger than the NH···Fe IHB in 1 by 6 kJ mol–1, as determined by IR spectroscopy. Further, we probed the E/Z isomer directing abilities of NH···M IHBs in the synthesis of the mixed metallocenyl compound ferrocenyl ruthenocenyl tosyl hydrazone (3). 3 is obtained as a mixture of the Z and E isomers (3a,b) with NH···Ru and NH···Fe IHBs, respectively. At 111 °C, 3a is …

chemistry.chemical_classification010405 organic chemistryHydrogen bondOrganic ChemistryInfrared spectroscopyHydrazone010402 general chemistryPhotochemistry01 natural sciencesMedicinal chemistry0104 chemical sciencesInorganic Chemistrychemistry.chemical_compoundTosylchemistryIntramolecular forcePhysical and Theoretical ChemistryOrganometallics
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Arynic species II

1986

Abstract o-Benzyne and its 4-methyl, 4-chloro and 4-bromo-derivatives were generated in the thermal decomposition of two new kinds of polymer-bound precursors: 1(2-carboxyaryl)triazenes and 2-carboxyaryl-sulphonates. New kinds of trapping polymers for these elusive species are also presented.

chemistry.chemical_classificationDiazonium CompoundsOrganic ChemistryThermal decompositionLeaving groupReaction intermediateBiochemistryArynechemistry.chemical_compoundBenzylaminechemistryTosylDrug DiscoveryPolymer chemistryOrganic chemistryTriazeneTetrahedron
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Diferrocenyl tosyl hydrazone with an ultrastrong NHFe hydrogen bond as double click switch.

2014

The intramolecular NH⋯Fe hydrogen bond in diferrocenyl hydrazone 2 raises the barrier for intramolecular electron transfer in its mixed-valent cation 2+ and is only disrupted by double oxidation to 22+.

chemistry.chemical_classificationHydrogen bondMetals and AlloysHydrazoneGeneral ChemistryPhotochemistryCatalysisSurfaces Coatings and FilmsElectronic Optical and Magnetic Materialschemistry.chemical_compoundElectron transferchemistryTosylIntramolecular forceMaterials ChemistryCeramics and CompositesChemical communications (Cambridge, England)
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Efficient alkali iodide promoted 18F-fluoroethylations with 2-[18F]fluoroethyl tosylate and 1-bromo-2-[18F]fluoroethane

2003

Abstract Radiochemical 18 F-fluorination yields of several compounds using the secondary labelling precursors 2-[ 18 F]fluoroethyl tosylate ([ 18 F]FETos) and 1-bromo-2-[ 18 F]fluoroethane ([ 18 F]BFE) could be considerably enhanced by the addition of an alkali iodide. The radiochemical yield of [ 18 F]fluoroethyl choline for example could be doubled with [ 18 F]BFE and increased from 13% to ≈80% with [ 18 F]FETos. By addition of alkali iodide to the precursor, the 18 F-fluoroethylation yields of established radiopharmaceuticals, especially in the case of automated syntheses, could be significantly increased without major changes of the reaction conditions.

chemistry.chemical_classificationReaction conditionsOrganic ChemistryIodideAlkali metalBiochemistrychemistry.chemical_compoundFluoroethyl tosylatechemistryYield (chemistry)LabellingDrug DiscoveryCholineFluoroethylNuclear chemistryTetrahedron Letters
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Unprecedented intermolecular transamidation reaction of N-carbamoylmethyl-N'-tosylguanidines.

2003

[reaction: see text] N-Carbamoylmethyl-N'-tosyl guanidine 2 reacts easily with primary alkylamines to afford substituted carboxamides 3. The reaction proceeds via a five-membered-ring intermediate 5, which could be isolated, and features a rare example of an intermolecular transamidation reaction under mild conditions.

chemistry.chemical_compoundPrimary (chemistry)TosylchemistryOrganic ChemistryIntermolecular forceOrganic chemistryPhysical and Theoretical ChemistryGuanidineBiochemistryMedicinal chemistryOrganic letters
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ChemInform Abstract: E,Z-Stereodivergent Synthesis of N-Tosyl α,β-Dehydroamino Esters via a Mukaiyama-Michael Addition

2016

The stereodivergent synthesis of N-tosyl α,β-dehydroamino esters via a Mukaiyama–Michael addition is reported. The reaction of silylketene acetals with N-tosylimines derived from β,γ-unsaturated α-keto esters in dichloromethane provided the corresponding (Z)-α,β-dehydroamino esters while the (E)-isomers were obtained when the reaction was carried out in the presence of 10 mol% copper(II) triflate.

chemistry.chemical_compoundTosylchemistryMichael reactionchemistry.chemical_elementGeneral MedicineMedicinal chemistryTrifluoromethanesulfonateCopperDichloromethaneChemInform
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Naphthalene-2,6-diyl bis(4-methylbenzenesulfonate)

2018

The complete molecule of the title compound, C24H20O6S2, is generated by a crystallographic inversion centre at the middle of the naphthalene ring system. The dihedral angle between the naphthalene ring system and the pendant benzene ring is 10.23 (6)° and the C—S—O—C torsion angle is −172.05 (10)°. In the crystal, weak C—H...O interactions link the molecules into (10-1) sheets.

crystal structure010405 organic chemistryChemistryGeneral MedicineCrystal structureDihedral angle010402 general chemistryRing (chemistry)01 natural sciencesCoupling reactioncrosscoupling reactions0104 chemical sciencesCrystalCrystallographychemistry.chemical_compoundSulfonatecross-coupling reactionslcsh:QD901-999lcsh:CrystallographyPhysics::Chemical PhysicsBenzenetosylatesNaphthaleneIUCrData
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4-Chloronaphthalen-1-yl 4-methylbenzenesulfonate

2018

In the title compound, C17H13ClO3S, the naphthalene ring system and the benzene ring of the tosylate substituent are inclined to one another by 55.32 (5)°. The crystal structure features weak intermolecular C—H...O hydrogen bonds, one of which forms inversion dimers. Additional C—H...O hydrogen bonds and weak Cl...Cl halogen bonds stack the molecules along the b-axis direction.

crystal structure010405 organic chemistryChemistryHydrogen bondSubstituentGeneral MedicineCrystal structure010402 general chemistryRing (chemistry)01 natural sciencesMedicinal chemistryCoupling reactioncrosscoupling reactions0104 chemical scienceschemistry.chemical_compoundSulfonatecross-coupling reactionsHalogenlcsh:QD901-999lcsh:CrystallographyPhysics::Chemical PhysicsBenzenetosylatesIUCrData
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3,5-Dimethoxyphenyl 4-methylbenzenesulfonate

2017

Molecules of the title compound, C15H16O5S, are composed of a 3,5-dimethoxyphenyl moiety substituted with a toluene-4-sulfonate group. The dihedral angle between two aromatic rings is 57.23 (4)°. In the crystal, molecules are connected by weak C—H...O hydrogen bonds and S...O van der Waals interactions.

crystal structure010405 organic chemistryHydrogen bondStereochemistryChemistryAromaticityCrystal structuretosyl­atesDihedral angle010403 inorganic & nuclear chemistry01 natural sciencesMedicinal chemistryCoupling reaction0104 chemical sciencessymbols.namesakechemistry.chemical_compoundSulfonatecross-coupling reactionssymbolsMoietyvan der Waals forceIUCrData
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3,5-Bis(trifluoromethyl)phenyl 4-methylbenzenesulfonate

2017

Molecules of the title compound, C15H10F6O3S, are composed of 3,5-bis(trifluoromethyl)phenyl substituted with a toluene-4-sulfonate group. The dihedral angle between two aromatic moieties is 45.10 (5)°. In the crystal, molecules are connected by weak C—H...O and C—H...F contacts. One of the trifluoromethyl groups is disordered.

crystal structure010405 organic chemistryMeth-Crystal structuretosyl­atesDihedral angle010402 general chemistry01 natural sciencesCoupling reaction0104 chemical sciencesCrystalchemistry.chemical_compoundSulfonatecross-coupling reactionschemistryGroup (periodic table)Polymer chemistryMethyl benzeneIUCrData
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