Search results for "Triticum"

showing 10 items of 118 documents

Nitration of Wheat Amylase Trypsin Inhibitors Increases Their Innate and Adaptive Immunostimulatory Potential

2018

Amylase trypsin inhibitors (ATI) can be found in all gluten containing cereals and are, therefore, ingredient of basic foods like bread or pasta. In the gut ATI can mediate innate immunity via activation of the Toll-like receptor 4 (TLR4) on immune cells residing in the lamina propria, promoting intestinal, as well as extra-intestinal, inflammation. Inflammatory conditions can induce formation of peroxynitrite (ONOO-) and, thereby, endogenous protein nitration in the body. Moreover, air pollutants like ozone (O3) and nitrogen dioxide (NO2) can cause exogenous protein nitration in the environment. Both reaction pathways may lead to the nitration of ATI. To investigate if and how nitration mo…

0301 basic medicinelcsh:Immunologic diseases. AllergyCell SurvivalT cellnon-celiac wheat sensitivityImmunologyInflammationAdaptive ImmunityImmunophenotyping03 medical and health scienceschemistry.chemical_compound0302 clinical medicineImmune systemprotein nitrationT-Lymphocyte SubsetsNitrationCell Line TumorwheatmedicineImmunology and AllergyHumansamylase trypsin inhibitorsTriticumPlant ProteinsOriginal ResearchInnate immune systemMacrophagesfood and beveragesDendritic CellsTetranitromethaneallergyImmunity InnateToll-Like Receptor 4030104 developmental biologymedicine.anatomical_structurechemistryBiochemistryAmylasesTLR4Cytokinesmedicine.symptomlcsh:RC581-607Trypsin InhibitorsPeroxynitriteBiomarkers030215 immunologyFrontiers in immunology
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Use of the modified quick easy cheap effective rugged and safe sample preparation approach for the simultaneous analysis of type A- and B-trichothece…

2010

A suitable extraction and purification method for the simultaneous liquid chromatography-mass spectrometry (LC-MS) determination of five mycotoxins, three type A, diacetoxyscirpenol (DAS), T-2 toxin (T-2) and HT-2 toxin (HT-2), and two type B-trichothecenes, deoxynivalenol (DON) and nivalenol (NIV), has been optimised using a modified "Quick Easy Cheap Effective Rugged and Safe" (QuEChERS) method. Different solvents were studied in the extraction procedure to obtain better recoveries, which ranged from 86 to 108%, using a 85/15 (v/v) mixture of methanol/acetonitrile. The values obtained for recovery, repeatability and reproducibility of the optimized method are in agreement with Commission …

AcetonitrilesChromatographyChemistryMethanolFlourOrganic ChemistryExtraction (chemistry)Wheat flourAnalytic Sample Preparation MethodsGeneral MedicineRepeatabilityQuechersBiochemistryMass SpectrometryDiacetoxyscirpenolAnalytical Chemistrychemistry.chemical_compoundVomitoxinLiquid chromatography–mass spectrometrySolventsSample preparationTrichothecenesTriticumChromatography LiquidJournal of Chromatography A
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WHOLE-meal ancient wheat-based diet: Effect on metabolic parameters and microbiota.

2021

Abstract Background & Aims Ancient wheat varieties are considered to be healthier than modern ones, but the data are not univocal. We investigated changes in hematochemical parameters and evaluated microbiota data before and after a set period on a diet containing a whole-meal ancient wheat mix. Patients and Methods 29 cloistered nuns were recruited. The study comprised two consecutive 30-day periods; during the first one (T1), the nuns received wheat-based foods produced with refined “modern” flour (“Simeto”); during the second one (T2) received wheat-based foods produced with an unrefined flour mix composed of “ancient” cultivars. At entry to the study (T0) and at the end of T1 and T2 hem…

Adult03 medical and health scienceschemistry.chemical_compoundFeces0302 clinical medicineMetabolomeMedicineHumansCultivarFood scienceWhole-meal wheatTriticumAgedMealAncient wheatHepatologybiologymedicine.diagnostic_testbusiness.industryGastroenterologyfood and beveragesMiddle Agedbiology.organism_classificationAncient wheat Diet Whole-meal wheatLactic acidDietGastrointestinal MicrobiomeFerritinFolic acidchemistry030220 oncology & carcinogenesisSerum ironbiology.proteinFece030211 gastroenterology & hepatologyFemalebusinessBacteriaHumanDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
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Quality, functional and sensory evaluation of pasta fortified with extracts from Opuntia ficus-indica cladodes

2019

Background The stems of Opuntia ficus-indica, known as cladodes, are a rich source of soluble fibers, which makes them an important candidate for the production of functional foods. Tagliatelle of durum wheat fortified with Opuntia cladode extract (OCE) at different levels of addition (10-30%, v/w) was prepared on a laboratory scale and quality characteristics and sensory acceptability were assessed. Results The main quality parameters (optimal cooking time, swelling index, cooking loss, dry matter) and sensory analysis on a nine-point hedonic scale were comparable with those of the control pasta sample (no added OCE) when durum wheat was supplemented with OCE at up to 20% (v/w). An in vitr…

AdultDietary FiberMaleQuality Controlin vitro digestion030309 nutrition & dieteticsOpuntia ficusStarch digestionSensory analysisGastrointestinal digestionfunctional foodYoung Adult03 medical and health sciences0404 agricultural biotechnologysterols bioaccesibilityOpuntia cladode extract; functional food; in vitro digestion; sterols bioaccesibilitySettore BIO/10 - BiochimicaCladodesHumansDry matterCookingFood scienceQuality characteristicsTriticumAgedOpuntia cladode extract0303 health sciencesNutrition and DieteticsbiologyPlant ExtractsChemistryOpuntiafood and beverages04 agricultural and veterinary sciencesMiddle Agedbiology.organism_classification040401 food scienceSettore CHIM/08 - Chimica FarmaceuticaGastrointestinal TractTasteFood FortifiedBlood cholesterolDigestionFemaleAgronomy and Crop ScienceFood ScienceBiotechnology
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Contact dermatitis due to nickel allergy in patients suffering from non-celiac wheat sensitivity

2017

Background: Non‐celiac wheat sensitivity (NCWS) is a new clinical entity in the world of gluten‐related diseases. Nickel, the most frequent cause of contact allergy, can be found in wheat and results in systemic nickel allergy syndrome and mimics irritable bowel syndrome (IBS). Objective: To evaluate the frequency of contact dermatitis due to nickel allergy in NCWS patients diagnosed by a double‐blind placebo‐controlled(DBPC)challenge,and to identify the characteristics of NCWS patients with nickel allergy. Methods: We performed a prospective study of 60 patients (54 females, 6 males; mean age 34.1 ± 8.1 years) diagnosed with NCWS from December 2014 to November 2016; 80 age‐ and sex‐matched…

AdultMale0301 basic medicineNickel allergymedicine.medical_specialtyLetterSettore MED/09 - Medicina InternaNon-celiac wheat sensitivitynon-celiac wheat insensitivityNickel allergyWheat HypersensitivityArticlecutaneous symptoms03 medical and health sciences0302 clinical medicineDouble-Blind MethodNickelHypersensitivitymedicineCutaneous symptomHumansIngestionIn patientProspective StudiesProspective cohort studysystemic nickel allergy syndromeTriticumIrritable bowel syndromeNutrition and Dieteticsbusiness.industryCase-control studyPatch testnon‐celiac  wheat  sensitivity;  nickel  allergy;  cutaneous  symptoms;  irritable  bowel  syndromeCutaneous symptoms; Irritable bowel syndrome; Nickel allergy; Non-celiac wheat sensitivity; Food SciencePatch Testsmedicine.diseaseintradermal testingDermatologySurgeryIrritable bowel syndromenickel allergy ; non-celiac wheat sensitivity ; irritable bowel syndrome ; cutaneous symptoms030104 developmental biologyCase-Control StudiesDermatitis Allergic ContactFemale030211 gastroenterology & hepatologybusinessContact dermatitisFood Science
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Different effectiveness of two pastas supplemented with either lipophilic or hydrophilic/phenolic antioxidants in affecting serum as evaluated by the…

2017

Effectiveness in improving serum antioxidant status of two functional pastas was evaluated by the novel Antioxidant/ Oxidant Balance (AOB) parameter, calculated as Antioxidant Capacity (AC)/Peroxide Level ratio, assessed here for the first time. In particular, Bran Oleoresin (BO) and Bran Water (BW) pastas, enriched respectively with either lipophilic (tocochromanols, carotenoids) or hydrophilic/phenolic antioxidants extracted from durum wheat bran, were studied. Notably, BO pasta was able to improve significantly (+65%) serum AOB during four hours after intake similarly to Lisosan G, a wheat antioxidant-rich dietary supplement. Contrarily, BW pasta had oxidative effect on serum so as conve…

AdultMaleSerumAntioxidantmedicine.medical_treatmentPeroxideAntioxidantsAnalytical Chemistrychemistry.chemical_compoundYoung Adult0404 agricultural biotechnologyPhenolsmedicineHumansFood sciencePhenolsOleoresinCarotenoidTriticumchemistry.chemical_classificationABTSBranPlant ExtractsTEACMedicine (all)Human serumfood and beveragesReproducibility of Results04 agricultural and veterinary sciencesGeneral MedicineOxidants040401 food scienceCarotenoidsDurum wheat antioxidantLOX-FLSettore AGR/02 - Agronomia E Coltivazioni ErbaceeFunctional pastachemistryBiochemistryDietary SupplementsORACFemaleTroloxLisosan GOxidation-ReductionFood ScienceFood chemistry
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A comparison between two different in vitro basophil activation tests for gluten- and cow's milk protein sensitivity in irritable bowel syndrome (IBS…

2013

Abstract Background: The diagnosis of food hypersensitivity (FH) in adult patients with gastrointestinal symptoms, beyond the immediate IgE-mediated clinical manifestations, is very often difficult. The aims of our study were to: 1) evaluate the frequency of FH in patients with irritable bowel syndrome (IBS)-like clinical presentation; and 2) compare the diagnostic accuracy of two different methods of in vitro basophil activation tests. Methods: Three hundred and five patients (235 females, age range 18–66 years) were included and underwent a diagnostic elimination diet and successive double-blind placebo-controlled (DBPC) challenges. Two different methods of in vitro basophil activation te…

AdultMaleSettore MED/09 - Medicina InternaAdolescentGlutensClinical Biochemistrygluten-sensitivityIrritable Bowel SyndromeYoung AdultElimination dietMedicineHumansYoung adultIrritable bowel syndromeTriticumWhole bloodAgedchemistry.chemical_classificationCD63business.industryBiochemistry (medical)General MedicineMiddle Agedmedicine.diseaseMilk ProteinsGlutenIn vitroBasophilsBasophil activationCeliac Diseasebasophil activation test; gluten-sensitivity; irritable bowel syndromechemistrybasophil activation testImmunologyFemaleMilk Hypersensitivitybusiness
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Oligo-antigenic diet in the treatment of chronic anal fissures. Evidence for a relationship between food hypersensitivity and anal fissures.

2013

Abstract OBJECTIVES: Patients with chronic constipation due to food hypersensitivity (FH) had an elevated anal sphincter resting pressure. No studies have investigated a possible role of FH in anal fissures (AFs). We aimed to evaluate (1) the effectiveness of diet in curing AFs and to evaluate (2) the clinical effects of a double-blind placebo-controlled (DBPC) challenge, using cow's milk protein or wheat. METHODS: One hundred and sixty-one patients with AFs were randomized to receive a "true-elimination diet" or a "sham-elimination diet" for 8 weeks; both groups also received topical nifedipine and lidocaine. Sixty patients who were cured with the "true-elimination diet" underwent DBPC cha…

AdultMalemedicine.medical_specialtySettore MED/09 - Medicina InternaConstipationManometryTreatment outcomeFood habitsSettore MED/08 - Anatomia PatologicaGastroenterologyFissure in anolaw.inventionLeukocyte CountFeeding behaviorRandomized controlled trialDouble-Blind MethodlawRecurrenceInternal medicinemedicineHumansLymphocyte CountLymphocytesIntestinal MucosaTriticumHepatologybusiness.industryGastroenterologyFeeding BehaviorMiddle AgedMilk ProteinsSettore MED/45 - Scienze Infermieristiche Generali Cliniche E PediatricheFood hypersensitivitySurgeryEosinophilsSettore MED/18 - Chirurgia GeneraleChronic diseaseTreatment OutcomeChronic DiseasefissureFemaleFissure in Anohypersensitivitymedicine.symptomMilk HypersensitivitybusinessConstipationFood HypersensitivityThe American journal of gastroenterology
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Wheat consumption leads to immune activation and symptom worsening in patients with familial mediterranean fever : a pilot randomized trial

2020

We have identified a clinical association between self-reported non-celiac wheat sensitivity (NCWS) and Familial Mediterranean Fever (FMF). Objectives: A) To determine whether a 2-week double-blind placebo-controlled (DBPC) cross-over wheat vs. rice challenge exacerbates the clinical manifestations of FMF

AdultMalenon-celiac wheat sensitivityCD14 lymphocytesLipopolysaccharide Receptors610 Medizinlcsh:TX341-641Wheat HypersensitivityMonocytesArticleDouble-Blind MethodAIDAI score610 Medical sciencesHumansTriticumCross-Over Studiesinterleukin-1betaTumor Necrosis Factor-alphaCD14 lymphocytefood and beveragesFamilial Mediterranean FeverDisease ProgressionFemaletumor necrosis factor-αlcsh:Nutrition. Foods and food supplyamylase trypsin inhibitor
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Limited survey for the occurrence of aflatoxins in cereals and poultry feeds from Rabat, Morocco

2007

Fifty eight (58) samples of cereals for human consumption (20 corn flour, 17 wheat flour) and poultry feeds (n=21) purchased from popular markets of Rabat in Morocco were analyzed for aflatoxins (AF) by HPLC with immunoaffinity column (IAC) clean-up and fluorimetric detection. The incidence of AF in corn, wheat flour and poultry feeds was about 80, 17.6 and 66.6% respectively. High contamination levels were found in corn and poultry feeds samples. Levels of contamination of analyzed samples with AFB1 ranged from 0.23 to 11.2, 0.03 to 0.15 and 0.05 to 5.38 ng/g for corn, wheat and poultry feeds respectively. Results showed also that the contamination of 10% of samples of corn was higher than…

AflatoxinWheat flourFood ContaminationBiologyZea maysMicrobiologyToxicologychemistry.chemical_compoundAflatoxinsCorn flourAnimalsFood scienceMycotoxinChromatography High Pressure LiquidPoultry DiseasesTriticumIncidencefood and beveragesGeneral MedicineContaminationAnimal FeedMoroccochemistryEdible GrainChickensFood ScienceInternational Journal of Food Microbiology
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