Search results for "Umbel"

showing 10 items of 31 documents

Crotonic acid as a bioactive factor in carrot seeds (Daucus carota L.)

2004

Water extracts from the carrot seed (Daucus carota L.) var. Perfekcja exhibit plant growth inhibitory properties against cress, cucumber, onion and carrot in a dose-dependant manner. This property results from the action of low-and high-molecular components of the extract. The low-molecular component was identified as crotonic acid ((E)-2-butenoic acid). Its presence was also confirmed in other late varieties of carrot. The determined strong herbicidal properties of crotonic acid and its availability after release to soil combined with its high level in seeds suggest that it might be considered as an allelopathic and autotoxic factor in the seeds.

Plant growthMagnetic Resonance SpectroscopyumbelliferaePlant ScienceHorticulturePlant RootsBiochemistrychemistry.chemical_compoundautotoxic activityOnionsCrotonic acidBotanyBioassayherbicidal activityMolecular BiologyAllelopathyDose-Response Relationship DrugMolecular StructurebiologyHerbicidesPlant ExtractsLiliaceaefood and beveragesGeneral MedicinePesticidebiology.organism_classificationHypocotylDaucus carotaHorticulturechemistrycrotonic acidCrotonatesallelopathyBrassicaceaeSeedsCucumis sativusDaucus carotaPhytochemistry
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Cytotoxic activity of diterpenoids isolated from the aerial parts of Elaeoselinum asclepium subsp. meoides.

2008

The phytochemical investigation of the acetone extract of the aerial parts of Elaeoselinum asclepium (L.) Bertol. subsp. meoides (Desf.) Fiori afforded several known diterpenoids as well as meoidic acid ( 5), new in the literature. The cytotoxic activities of elasclepic acid ( 1), ENT-atis-16-en-19-oic acid ( 2), ent-beyer-15-en-19-oic acid ( 3), ent-kaur-16-en-19-oic acid ( 4) and meoidic acid ( 5) were investigated on rat glioma C6 cells by evaluation of cell growth inhibition.

StereochemistryElaeoselinum asclepium subsp. meoides Umbelliferae diterpenoids meoidic acid cytotoxic activityPharmaceutical ScienceBiologyPharmacognosyAnalytical Chemistrychemistry.chemical_compoundCell Line TumorDrug Discoveryotorhinolaryngologic diseasesAcetoneCytotoxic T cellAnimalsCytotoxicityCell ProliferationPharmacologyMolecular StructureOrganic ChemistrySettore CHIM/06 - Chimica OrganicaElaeoselinum asclepium subsp. meoidesAntineoplastic Agents PhytogenicTerpenoidRatsComplementary and alternative medicinechemistryPhytochemicalMolecular MedicineDiterpeneDiterpenesApiaceaePlanta medica
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ChemInform Abstract: Two New Sesquiterpene Derivatives from the Tunisian Endemic Ferula tunetana Pom.

2010

A new sesquiterpene ester, tunetanin A (1), a new sesquiterpene coumarin, tunetacoumarin A (2), together with eight known compounds, i.e., coladin (3), coladonin (4), isosmarcandin (5), 13-hydroxyfeselol (6), umbelliprenin (7) propiophenone (8), beta-sitosterol (9), and stigmasterol (10), were isolated from the roots of Ferula tunetana. Their structures were elucidated on the basis of extensive spectroscopic methods, including 1D- and 2D-NMR experiments and MS analysis, as well as by comparison with published data. The cytotoxicity of compounds 1-7 towards two human colon cancer cell lines, HT-29 and HCT 116, was evaluated. Compounds 3, 4, and 6 showed weak cytotoxic activities.

Terpenechemistry.chemical_compoundStigmasterolchemistryPropiophenoneStereochemistryFerula tunetanaGeneral MedicineSesquiterpeneCytotoxicityCoumarinUmbellipreninChemInform
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ChemInform Abstract: New Umbelliferone Sesquiterpene Ethers from Roots of Ligularia persica.

2010

An extract of roots of Ligularia persica yielded thirteen umbelliferone sesquiterpene ethers, among them the new ones ligupersin A (11) and ligupersin B (13).

Terpenechemistry.chemical_compoundchemistryTraditional medicinebiologyLigulariaGeneral MedicineSesquiterpeneUmbelliferonebiology.organism_classificationChemInform
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New umbelliferone sesquiterpene ethers from roots ofLigularia persica

1991

An extract of roots of Ligularia persica yielded thirteen umbelliferone sesquiterpene ethers, among them the new ones ligupersin A (11) and ligupersin B (13).

biologyBicyclic moleculeStereochemistryLigulariaOrganic ChemistryEtherNuclear magnetic resonance spectroscopySesquiterpenebiology.organism_classificationUmbelliferoneCoumarinchemistry.chemical_compoundchemistryOrganic chemistryPhysical and Theoretical ChemistryLiebigs Annalen der Chemie
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Organic and chemical n fertilization on coriander (coriandrum sativum L.) in a Mediterranean environment

2014

Abstract Coriander (Coriandrum sativum L.) is an annual herbaceous Medicinal and Aromatic Plant (MAP) dealing with a great industrial interest because of its strongly-scented fruits (“seeds”). The role of N fertilization in coriander seed yield is matter of debate as far; information is missing, for instance, about the effects of organic N fertilization, a mandatory technique when the organic cropping management is chosen. Organic and chemical N fertilizers have been supplied on coriander from 2001–2002 to 2006–2007 in a Mediterranean semi-arid environment, and their effects on the formation of biomass and seeds yield have been evaluated. Different organic fertilizers, allowed by EU regulat…

biologyCoriandrumUmbelfood and beveragesSowingBiomassengineering.materialStrawbiology.organism_classificationHorticultureSativumAgronomyengineeringOrganic farmingFertilizerAgronomy and Crop ScienceMathematicsIndustrial Crops and Products
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New Triterpenoid and Ergostane Glycosides from the Leaves of Hydrocotyle umbellata L.

2011

Two new triterpenoid glycosides, together with two new ergostane glycosides, umbellatosides A–D (1–4, resp.), have been isolated from the leaves of Hydrocotyle umbellata L. Their structures were established by 2D-NMR spectroscopic techniques (1H,1H-COSY, TOCSY, NOESY, HSQC, and HMBC) and mass spectrometry as 3β,22β-dihydroxy-3-O-[α-L-rhamnopyranosyl-(12)-β-D-glucuronopyranosyl]olean-12-en-28-oic acid 28-O-β-D-glucopyranosyl ester (1), 3-O-[α-L-rhamnopyranosyl-(12)-β-D-glucuronopyranosyl]oleanolic acid 28-O-β-D-glucopyranosyl ester (2), (3β,11α,26)-ergosta-5,24(28)-diene-3,11,26-triol 3-O-(β-D-glucopyranosyl)-11-O-(α-L-rhamnopyranosyl)-26-O-β-D-glucopyranoside (3), and (3β,11α,21,26)-ergosta…

chemistry.chemical_classificationErgostanebiologyStereochemistryOrganic ChemistryGlycosideHydrocotyle umbellataMass spectrometrybiology.organism_classificationBiochemistryCatalysisInorganic ChemistryTerpenechemistry.chemical_compoundTriterpenoidchemistryDrug DiscoveryOrganic chemistryPhysical and Theoretical ChemistryOleanolic acidTwo-dimensional nuclear magnetic resonance spectroscopyHelvetica Chimica Acta
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Two New Flavonoids fromBonannia graeca: a DFT-NMR Combined Approach in Solving Structures

2007

Two new cyclized C-geranylated flavonoids, the dihydroflavonol bonanniol C (4a) and the flavanone bonannione B (6a), were isolated as minor compounds from the aerial parts of Bonannia graeca (Umbelliferae). Their structures were elucidated by a combined approach of extensive spectroscopic means and quantum mechanical methods. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)

chemistry.chemical_compoundchemistryStereochemistryOrganic ChemistrySettore CHIM/06 - Chimica OrganicaPhysical and Theoretical ChemistryUmbelliferae Bonannia graeca Geranylated flavonoids DFTFlavanoneCombined approachEuropean Journal of Organic Chemistry
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In vitro glucuronidation of 7-hydroxycoumarin derivatives in intestine and liver microsomes of Beagle dogs

2019

Beagle dog is a standard animal model for evaluating nonclinical pharmacokinetics of new drug candidates. Glucuronidation in intestine and liver is an important first-pass drug metabolic pathway, especially for phenolic compounds. This study evaluated the glucuronidation characteristics of several 7-hydroxycoumarin derivatives in beagle dog's intestine and liver in vitro. To this end, glucuronidation rates of 7-hydroxycoumarin (compound 1), 7-hydroxy-4-trifluoromethylcoumarin (2), 6-methoxy-7-hydroxycoumarin (3), 7-hydroxy-3-(4-tolyl)coumarin (4), 3-(4-fluorophenyl)coumarin (5), 7-hydroxy-3-(4-hydroxyphenyl)coumarin (6), 7-hydroxy-3-(4-methoxyphenyl)coumarin (7), and 7-hydroxy-3-(1H-1,2,4-t…

entsyymitColonGlucuronidationPharmaceutical Science02 engineering and technologyliver030226 pharmacology & pharmacyBeaglekoira7-hydroxycoumarin derivative03 medical and health scienceschemistry.chemical_compound0302 clinical medicineDogsGlucuronidesPharmacokineticsMicrosomesenzyme kineticsIntestine SmallmedicineAnimalsHumansUmbelliferonesGlucuronosyltransferasekumariinitaineenvaihduntachemistry.chemical_classificationChemistryglucuronidationdog intestinemaksaMetabolismlääkeaineet021001 nanoscience & nanotechnologyCoumarinSmall intestineEnzymemedicine.anatomical_structureBiochemistryLiverfarmakokinetiikkasuolistoMicrosomekoe-eläinmallit0210 nano-technology
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Allelochemia marchwi (Daucus carota L.)

2000

marchew jadalnaUmbelliferaeaktywność allelopatycznaallelopatiaolej z nasionallelozwiązkibaldaszkowatewłaściwości allelopatyczneDaucus carotaBioTechnologia Journal of Biotechnology, Computational Biology and Bionanotechnology
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