Search results for "Variants"
showing 10 items of 227 documents
Anatomical variants and anomalies of the coronary tree studied with MDCT coronary angiography
2010
Le anomalie delle arterie coronariche sono presenti alla nascita nella maggior parte dei casi asintomatiche ma possono manifestarsi con sintomatologia severa quale angina pectoris o addirittura l’arresto cardiaco. L’angiografia coronarica mediante tomografia computerizzata multistrato (TCMS) permette, tramite ricostruzioni multiplanari secondo piani curvilinei e riformattazioni 3D, la visualizzazione dell’albero coronarico e delle sue varianti ed anomalie in maniera non invasiva, fornendo migliore e più accurata alternativa alla angiografia coronarica (AC). Lo scopo di questo pictorial consiste nella descrizione mediante immagini TCMS con ricostruzioni multiplanari e 3D delle principali var…
Gestācijas dominantes psiholoģiskās komponentes hipogestognostiskā varianta izplatība un saistība ar atioforiognoziju dzemdību palīdzības iestādes pa…
2015
Ievads. Gestācijas dominantes psiholoģiskā komponente ir psihisko pašregulācijas mehānismu kopums grūtniecības saglabāšanai. Hipogestognostiskais variants raksturīgs sievietēm, kuras apzināti vai biežāk neapzināti nepieņem savu grūtniecību. Sakarā ar to, ka gestācijas dominantes psiholoģiskās komponentes hipogestognostiskais variants ir cieši saistīts ar grūtniecības noliegšanu, kas apdraud gan mātes, gan bērna dzīvību, nepieciešams pēc iespējas agrīni novērtēt grūtnieces psiholoģisko stāvokli. Pētījuma mērķis. Veicot prospektīvo pētījumu novērtēt grūtnieču gestācijas dominantes psiholoģiskās komponentes hipogestognostiskā varianta biežumu, kā arī noskaidrot grūtniecības nelabvēlīga iznākum…
Fast and low-cost decentralized surveillance of transmission of tuberculosis based on strain-specific PCRs tailored from whole genome sequencing data…
2015
Molecular epidemiology has transformed our knowledge of how tuberculosis (TB) is transmitted. Whole genome sequencing (WGS) has reached unprecedented levels of accuracy. However, it has increased technical requirements and costs, and analysis of data delays results. Our objective was to find a way to reconcile speed and ease of implementation with the high resolution of WGS. The targeted regional allele-specific oligonucleotide PCR (TRAP) assay presented here is based on allele-specific PCR targeting strain-specific single nucleotide polymorphisms, identified from WGS, and makes it possible to track actively transmitted Mycobacterium tuberculosis strains. A TRAP assay was optimized to track…
A look into the future of the COVID-19 pandemic in Europe : an expert consultation
2021
How will the coronavirus disease 2019 (COVID-19) pandemic develop in the coming months and years? Based on an expert survey, we examine key aspects that are likely to influence COVID-19 in Europe. The future challenges and developments will strongly depend on the progress of national and global vaccination programs, the emergence and spread of variants of concern, and public responses to nonpharmaceutical interventions (NPIs). In the short term, many people are still unvaccinated, VOCs continue to emerge and spread, and mobility and population mixing is expected to increase over the summer. Therefore, policies that lift restrictions too much and too early risk another damaging wave. This ch…
A note on rank 2 diagonals
2020
<p>We solve two questions regarding spaces with a (G<sub>δ</sub>)-diagonal of rank 2. One is a question of Basile, Bella and Ridderbos about weakly Lindelöf spaces with a G<sub>δ</sub>-diagonal of rank 2 and the other is a question of Arhangel’skii and Bella asking whether every space with a diagonal of rank 2 and cellularity continuum has cardinality at most continuum.</p>
Topological invariants of stable immersions of oriented 3-manifolds in R4
2012
Abstract We show that the Z -module of first order local Vassiliev type invariants of stable immersions of oriented 3-manifolds into R 4 is generated by 3 topological invariants: The number of pairs of quadruple points and the positive and negative linking invariants l + and l − introduced by V. Goryunov (1997) [7] . We obtain the expression for the Euler characteristic of the immersed 3-manifold in terms of these invariants. We also prove that the total number of connected components of the triple points curve is a non-local Vassiliev type invariant.
Defining relations of minimal degree of the trace algebra of 3×3 matrices
2008
Abstract The trace algebra C n d over a field of characteristic 0 is generated by all traces of products of d generic n × n matrices, n , d ⩾ 2 . Minimal sets of generators of C n d are known for n = 2 and n = 3 for any d as well as for n = 4 and n = 5 and d = 2 . The defining relations between the generators are found for n = 2 and any d and for n = 3 , d = 2 only. Starting with the generating set of C 3 d given by Abeasis and Pittaluga in 1989, we have shown that the minimal degree of the set of defining relations of C 3 d is equal to 7 for any d ⩾ 3 . We have determined all relations of minimal degree. For d = 3 we have also found the defining relations of degree 8. The proofs are based …
Linear invariants of Riemannian almost product manifolds
1982
Using the decomposition of a certain vector space under the action of the structure group of Riemannian almost product manifolds, A. M. Naveira (9) has found thirty-six distinguished classes of these manifolds. In this article, we prove that this decomposition is irreducible by computing a basis of the space of invariant quadratic forms on such a space.
An overview of statin-induced myopathy and perspectives for the future
2020
Introduction: Statins remain the most commonly prescribed lipid-lowering drug class for the treatment of atherosclerotic cardiovascular disease. Their well-recognized side effects are known as statin-associated muscle symptom (SAMS). Some advances in this field have been made in recent years, but the understanding of the mechanisms has lagged. Investigating the specific role of the anti-HMGCR autoantibody, pharmacokinetic genetic variants, characterization of the known phenotypes of statin toxicity, in relation to clinical markers of disease, is of high importance. Areas covered: We summarized currently available findings (on PubMed) related to SAMS and discussed the therapeutic approaches,…
Genome-wide association study identifies five susceptibility loci for follicular lymphoma outside the HLA region.
2014
Genome-wide association studies (GWASs) of follicular lymphoma (FL) have previously identified human leukocyte antigen (HLA) gene variants. To identify additional FL susceptibility loci, we conducted a large-scale two-stage GWAS in 4,523 case subjects and 13,344 control subjects of European ancestry. Five non-HLA loci were associated with FL risk: 11q23.3 (rs4938573, p = 5.79 × 10 -20) near CXCR5; 11q24.3 (rs4937362, p = 6.76 × 10 -11) near ETS1; 3q28 (rs6444305, p = 1.10 × 10 -10) in LPP; 18q21.33 (rs17749561, p = 8.28 × 10 -10) near BCL2; and 8q24.21 (rs13254990, p = 1.06 × 10 -8) near PVT1. In an analysis of the HLA region, we identified four linked HLA-DRß1 multiallelic amino acids at p…