Search results for "Vt"

showing 10 items of 136 documents

Analysis of hybrid vehicle transmissions with any number of modes and planetary gearing: kinematics, power flows, mechanical power losses

2021

Abstract This paper is focused on upgrading a unified parametric model, available in the literature, that can perform both the analysis and the design of Power-Split Continuously Variable Transmissions (PS-CVTs), which are particularly promising to deploy in the hybrid electric powertrain. In particular, this work is focused on the analysis of PS-CVTs and proposes a new matrix approach for identifying the basic functional parameters underlying the model from the constructive layout of the transmission. This new method does not rely on a case-specific formulation, thus befits any power-split transmission, regardless of the number of planetary and ordinary gear sets and their constructive arr…

0209 industrial biotechnologyAnalysis Cadillac CT6 Hybrid electric vehicle Multimode transmission Planetary gearing Power-split CVTComputer sciencePowertrainMechanical EngineeringBioengineeringControl engineering02 engineering and technologyKinematicsConstructiveSettore ING-IND/13 - Meccanica Applicata Alle MacchineComputer Science ApplicationsPower (physics)020303 mechanical engineering & transports020901 industrial engineering & automation0203 mechanical engineeringTransmission (telecommunications)Mechanics of MaterialsParametric modelClutchHybrid vehicle
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Direct analysis of power-split CVTs: A unified method

2018

Abstract This paper provides a fast kinematic analysis method for compound power-split CVTs, which consents to identify their functional parameters. Such parameters permit the assessment of power flows, torques and efficiency, and the design of equivalent transmissions by the use of a recently published mathematical model. The same method can easily address either simpler or more complex transmissions by mean of kinematic equivalent parameters, without the need to arrange separate systems of equations. As a case study, we performed the kinematic analysis of the “Voltec” multi-mode GM transmission.

0209 industrial biotechnologyEngineeringPower-split CVTBioengineering02 engineering and technologyKinematicsSystem of linear equations020901 industrial engineering & automation0203 mechanical engineeringPower splitTorqueMechanics of MaterialContinuously variable transmissionDirect analysisAnalysis methodE-CVTbusiness.industryMechanical EngineeringComputer Science Applications1707 Computer Vision and Pattern RecognitionControl engineeringSettore ING-IND/13 - Meccanica Applicata Alle MacchineHybridGM VoltecComputer Science ApplicationsPower (physics)Direct analysi020303 mechanical engineering & transportsTransmission (telecommunications)Mechanics of MaterialsbusinessMechanism and Machine Theory
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Power losses in power-split CVTs: A fast black-box approximate method

2018

Abstract This paper addresses the mechanical losses of planetary transmissions, with particular attention to power-split CVTs in their hybrid electric versions. It provides unified layout-independent analytical relationships, which can be used for both analysis, design and control purposes, and a simplified approach; the latter overcomes the necessity to segment the operating range of the power-split CVT in order to keep its loss model physically consistent. An example of application to a real hybrid electric PS-CVT is performed to show the simplicity, accuracy and generality of the proposed method.

0209 industrial biotechnologyGeneralityHybrid electric vehicleComputer scienceMechanical EngineeringPower split CVTBioengineeringComputer Science Applications1707 Computer Vision and Pattern Recognition02 engineering and technologyGM voltecSettore ING-IND/13 - Meccanica Applicata Alle MacchineComputer Science ApplicationsPower (physics)020303 mechanical engineering & transports020901 industrial engineering & automation0203 mechanical engineeringPower splitMechanics of MaterialsControl theoryBlack boxSimplicity (photography)Range (statistics)Mechanics of MaterialPlanetary gearing losse
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VV. AA. (Obra coordinada por Tito Llopis / VTiM) L' escultor Josep Ginés i Marín (1768-1823). A propòsit de "La matança dels innocents" : Catálogo de…

2020

0211-5808 9678 Archivo de arte valenciano 564145 2020 101 7708003 VV. AA. (Obra coordinada por Tito Llopis / VTiM) L' escultor Josep Ginés i Marín (1768-1823). A propòsit de ?La matança dels innocents" Catálogo de la exposición de escultura celebrada en la Sala Ribalta del Museo de Bellas Artes de ValenciaUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRAS:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]de febrero a septiembre de 2020conmemorativa del 250 aniversario de la fundación de la Real Academia de Bellas Artes de San Carlos. Delicado Martínez0211-5808 9678 Archivo de arte valenciano 564145 2020 101 7708003 VV. AA. (Obra coordinada por Tito Llopis / VTiM) L' escultor Josep Ginés i Marín (1768-1823). A propòsit de "La matança dels innocents" Catálogo de la exposición de escultura celebrada en la Sala Ribalta del Museo de Bellas Artes de ValenciaFrancisco Javier 436 440
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Identification of clinical phenotypes and related survival in patients with large hccs

2021

Background. Hepatocellular carcinoma (HCC) factors, especially maximum tumor diameter (MTD), tumor multifocality, portal vein thrombosis (PVT), and serum alpha-fetoprotein (AFP), influence survival. Aim. To examine patterns of tumor factors in large HCC patients. Methods. A database of large HCC patients was examined. Results. A multiple Cox proportional hazard model on death identified low serum albumin levels and the presence of PVT and multifocality, with each having a hazard ratio ≥2.0. All combinations of these three parameters were examined in relation to survival. Using univariate Cox analysis, the combination of albumin &gt

0301 basic medicineCancer Researchmedicine.medical_specialtyPVTSettore MED/12 - GASTROENTEROLOGIASerum albuminlcsh:RC254-282GastroenterologyArticle03 medical and health sciences0302 clinical medicineInternal medicineMedicinePlateletHCCneoplasmsSurvival ratePVT.biologybusiness.industryProportional hazards modelAlbuminHazard ratioSettore MED/09 - MEDICINA INTERNAAlbuminMultifocalityHCC; large; phenotypes; PVT; multifocality; albuminlcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseasedigestive system diseasesPortal vein thrombosisAlbumin; HCC; Large; Multifocality; Phenotypes; PVTPhenotypesPhenotype030104 developmental biologyOncology030220 oncology & carcinogenesisHepatocellular carcinomabiology.proteinLargebusiness
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Recent advances on CDK inhibitors: An insight by means of in silico methods

2017

The cyclin dependent kinases (CDKs) are a small family of serine/threonine protein kinases that can act as a potential therapeutic target in several proliferative diseases, including cancer. This short review is a survey on the more recent research progresses in the field achieved by using in silico methods. All the "armamentarium" available to the medicinal chemists (docking protocols and molecular dynamics, fragment-based, de novo design, virtual screening, and QSAR) has been employed to the discovery of new, potent, and selective inhibitors of cyclin dependent kinases. The results cited herein can be useful to understand the nature of the inhibitor-target interactions, and furnish an ins…

0301 basic medicineQuantitative structure–activity relationshipMolecular dynamicIn silicoCDKQuantitative Structure-Activity RelationshipAntineoplastic AgentsComputational biologyMolecular Dynamics SimulationBioinformatics01 natural sciencesSerine03 medical and health sciencesCyclin-dependent kinaseNeoplasmsDrug DiscoveryAnimalsHumansProtein Kinase InhibitorsPharmacologyVirtual screeningHVTSbiologyChemistryKinaseQSARDrug Discovery3003 Pharmaceutical ScienceOrganic ChemistryGeneral MedicineCyclin-Dependent Kinases0104 chemical sciencesMolecular Docking Simulation010404 medicinal & biomolecular chemistry030104 developmental biologyDocking (molecular)Drug Designbiology.proteinComputer-Aided DesignIn silico methodMolecular modelling
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Use of Early Life-Stages of Zebrafish to Assess Toxicity of Sediments Contaminated by Organotin Compounds

2016

ABSTRACTThis study examined the response of early life-stages (ELS) of zebrafish to organotin-contaminated sediment from Lake Huruslahti (HL) in Central Finland. A dilution series (0, 10, 33, and 100%) of the native (HL) and the sediment spiked with tributyltin (TBT) determined a dose-response of zebrafish ELS to organotin-contaminated sediment. Sediment elutriates were assessed by bacterial bioluminescence assay and microscopical pathologies of 1–3 days post-fertilization zebrafish (1–3dpfZF). Brain aromatase (cyp19a1b) and tissue vitellogenin (vtg1) were assayed from early-juvenile zebrafish (20dpfZF) exposed to intact sediment. In vivo modulation of cyp19a1b and vtg1 transcripts in 20dpf…

0301 basic medicineneural aromatase (cyp19a1b)Health Toxicology and Mutagenesista1172Soil Science010501 environmental sciences01 natural sciencessediment assay in vivotributyltin03 medical and health scienceschemistry.chemical_compoundVitellogeninIn vivoEnvironmental ChemistryBioluminescenceZebrafish0105 earth and related environmental sciencesbiologySedimentAquatic animalbiology.organism_classificationzebrafishPollutionMolecular biologyvitellogenin 1 (vtg1)030104 developmental biologychemistryEnvironmental chemistryToxicityTributyltinbiology.proteinSoil and Sediment Contamination
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"Table 7" of "Search for resonant $WZ$ production in the fully leptonic final state in proton-proton collisions at $\sqrt{s} = 13$ TeV with the ATLAS…

2021

Observed and expected 95% C.L. upper limits on $\sigma\times$BR($W'\to W^\pm Z$) for the $VBF$ production of a $W'$ boson in the HVT model as a function of its mass. The $\pm1\sigma$ and $\pm2\sigma$ uncertainty are given in the expected limits. Limits are calculated in the asymptotic approximation below 700 GeV and are obtained from pseudo-experiments above that.

13000.0VBFlvllHigh Energy Physics::ExperimentHVTWZWPRIME --> W Z0W'
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"Table 6" of "Search for resonant $WZ$ production in the fully leptonic final state in proton-proton collisions at $\sqrt{s} = 13$ TeV with the ATLAS…

2021

Observed and expected 95% C.L. upper limits on $\sigma\times$BR($W'\to W^\pm Z$) for the q$\bar{\mathrm q}$ production of a $W'$ boson in the HVT model as a function of its mass. The $\pm1\sigma$ and $\pm2\sigma$ uncertainty in the expected limits are given. Limits are calculated in the asymptotic approximation below 900 GeV and are obtained from pseudo-experiments above that.

13000.0lvllDrell-YanHigh Energy Physics::ExperimentHVTWZWPRIME --> W Z0W'
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Coronavirus Disease 2019–Associated Coagulopathy

2021

Patients with the severe form of coronavirus disease 2019 (COVID-19) have been frequently found to suffer from both arterial and venous thrombotic events due to the perpetuation of a hypercoagulable state. This phenomenon, termed COVID-19-associated coagulopathy (CC), is now considered a major component of the pathophysiology of this novel infectious disease, leading to widespread thrombosis. While at first, the vascular insults may be limited to the pulmonary microvasculature, as the disease progresses, systemic involvement occurs, culminating in distant organ thrombosis and multi-organ dysfunction syndrome. In this review article, we discuss recent insights into the pathophysiologic mecha…

ARDSPAI-1 Plasminogen Activator Inhibitor 1VTE venous thromboembolismDiseaseReview030204 cardiovascular system & hematologyCoronavirus Disease 20190302 clinical medicineCoagulopathy030212 general & internal medicineDIC disseminated intravascular coagulationDisseminated intravascular coagulationCOVID-19 Coronavirus disease 2019DVT deep vein thrombosisGeneral MedicineBlood Coagulation DisordersThrombosisICU intensive care unitTMA thrombotic microangiopathyDisease ProgressionCoronavirus Disease 2019 COVID-19 CoagulopathyVWF von Willebrand factormedicine.medical_specialtyThrombotic microangiopathyACE2 angiotensin-converting enzyme 2SARS-CoV-2 severe acute respiratory syndrome coronavirus 203 medical and health sciencesmedicineCoagulopathyHumansIntensive care medicineLY30 lysis at 30 minutesARDS acute respiratory distress syndromeHemostasisNO nitric oxideCoagulationbusiness.industrySARS-CoV-2COVID-19Thrombosismedicine.diseasetPA tissue plasminogen activatorReview articleIL interleukinCoronavirusVascular DisorderPE pulmonary embolismTF tissue factorbusinessCC COVID-associated coagulopathyMayo Clinic Proceedings
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