Search results for "Wound"

showing 10 items of 534 documents

Experience in a Military Trauma Surgery Department with External Skeletal Fixation of Femur Fractures

1989

Our experience with external skeletal fixation of complex open and closed femoral fractures in 50 conventional trauma victims is presented. Different external fixator systems were primarily used in 26 patients and secondarily in 24 patients. The authors feel that early definitive femoral fracture care in civilian and military trauma victims employing unilateral external monofixation, which avoids casts, and allows improved wound management and early mobilization of the multitrauma patient, has decreased the complication rate commonly associated with internal fixation of open femoral fractures.

medicine.medical_specialtyExternal fixatorbusiness.industrymedicine.medical_treatmentPublic Health Environmental and Occupational HealthExternal skeletal fixationGeneral MedicineFemoral fracturemedicine.diseaseTrauma surgery departmentSurgeryWound managementMedicineInternal fixationFemurTrauma victimsbusinessMilitary Medicine
researchProduct

Fibrous Nanozyme Dressings with Catalase-Like Activity for H2O2 Reduction To Promote Wound Healing

2017

The concentrations of the redox pair hydrogen peroxide (H2O2) and oxygen (O2) can promote or decelerate the progression and duration of the wound healing process. Although H2O2 can reach critically high concentrations and prohibit healing, a sufficient O2 inflow to the wound is commonly desired. Herein, we describe the fabrication and use of a membrane that can contemptuously decrease H2O2 and increase O2 levels. Therefore, hematite nanozyme particles were integrated into electrospun and cross-linked poly(vinyl alcohol) membranes. Within the dual-compound membrane, the polymeric mesh provides a porous scaffold with high water permeability and the nanozymes act as a catalyst with catalase-li…

Vinyl alcoholMaterials sciencebiologytechnology industry and agriculturefood and beverages02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnology01 natural sciencesRedox0104 chemical sciencesCatalysischemistry.chemical_compoundMembranechemistryPermeability (electromagnetism)CatalaseBiophysicsbiology.proteinGeneral Materials ScienceComposite material0210 nano-technologyWound healingHydrogen peroxideACS Applied Materials & Interfaces
researchProduct

Sorbitol-penetration enhancer containing vesicles loaded with baicalin for the protection and regeneration of skin injured by oxidative stress and UV…

2018

Abstract Aiming at improving the protective effects of baicalin on the skin, new highly-biocompatible penetration enhancer containing vesicles (PEVs) were developed by modifying the base formulation of transfersomes with sorbitol, thus obtaining sorbitol-PEVs. An extensive evaluation of the physico-chemical features of both transfersomes and sorbitol-PEVs was carried out. Transfersomes were mainly close-packed, multi-compartment vesicles, while sorbitol-PEVs appeared mostly as single, spherical, unilamellar vesicles. All the vesicles were small in size (∼128 nm) and negatively charged (∼−67 mV), without significant differences between the formulations. The in vitro delivery of baicalin to i…

SwineUltraviolet RaysChemistry PharmaceuticalCellPharmaceutical Science02 engineering and technologymedicine.disease_cause030226 pharmacology & pharmacyCell LineExcipients03 medical and health scienceschemistry.chemical_compoundMice0302 clinical medicineDrug Delivery SystemsCell MovementmedicineAnimalsHumansRegenerationSorbitolParticle SizeCell ProliferationSkinFlavonoidsWound HealingCell growthVesicleRegeneration (biology)fungi3T3 Cells021001 nanoscience & nanotechnologyIn vitroOxidative Stressmedicine.anatomical_structurechemistryBiophysicsSorbitol0210 nano-technologyBaicalinOxidative stressInternational journal of pharmaceutics
researchProduct

Soft and hard tissue alterations around implants placed in an alveolar ridge with a sloped configuration.

2012

Aim: The aim of this study was to evaluate soft and hard tissue alterations around implants placed in healed, sloped ridge sites. Materials and methods: In this prospective multi-center study, 65 patients between 20 and 74 years of age and with a need for a single tooth replacement were included. All patients presented with a recipient implant site demonstrating a lingual‐buccal bone height discrepancy of 2.0‐5.0 mm and with a neighboring tooth on its mesial aspect. Implant placement (OsseoSpeed Profile implants; Astra Tech AB, M! olndal, Sweden) was performed using a non-submerged installation procedure. The implants were placed in such a way that the sloped part of the device was located …

AdultMalemedicine.medical_treatmentDentistryOsteotomyBone remodelingDental Implants Single-Toothstomatognathic systemPeriodontal Attachment LossmedicineAlveolar ridgeAlveolar ProcessHumansProspective StudiesTooth SocketDental alveolusAgedWound HealingCrownsbusiness.industryAlveolar processDental Implantation EndosseousBuccal administrationMiddle AgedOsteotomyRadiographystomatognathic diseasesmedicine.anatomical_structureTreatment OutcomeClinical attachment lossDental Prosthesis DesignFemaleImplantBone RemodelingOral SurgerybusinessClinical oral implants research
researchProduct

Extremely low frequency electromagnetic fields (ELF-EMFs) induce in vitro angiogenesis process in human endothelial cells.

2008

Effects of extremely low frequency (ELF) electromagnetic fields (EMFs) on activation of angiogenesis were analysed using cultured umbilical human vein endothelial cells (HUVECs). The cultures were exposed to a sinusoidal EMF to intensity of 1 mT, 50 Hz for up to 12 h. EMFs increased the degree of endothelial cell proliferation and tubule formation, coupled by an acceleration in the process of wound healing. Since this process is physiologically accompanied by a large modification in the structural organization of actin and focal adhesions, we analyzed the rearrangement of some cytoskeleton elements demonstrating a major reorganization of the fibres and of the focal adhesion complexes after …

animal structuresCytoskeleton organizationPhysiologyAngiogenesisBiophysicsNeovascularization PhysiologicBiologyRadiation DosageFocal adhesionElectromagnetic FieldsEndothelial cellElectricityHumansRadiology Nuclear Medicine and imagingTherapeutic angiogenesisCytoskeletonCells CulturedEndothelial CellsDose-Response Relationship RadiationGeneral MedicineCell biologyEndothelial stem cellAngiogenesiSignal transductionWound healingExtremely low frequency electromagnetic fieldsBioelectromagnetics
researchProduct

The European trauma course – trauma teaching goes European

2014

The World Health Organization (WHO) has identified trauma as the major health care challenge of our century, claiming more productive life years worldwide than any other disease [1]. In the European Union (EU), injury accounts for 15 % of all deaths before the age of 60 years and is the fourth most common cause of death, with more than 235,000 deaths each year from injuries, equating to 600 injury fatalities per day [2]. In children, adolescents and young adults, accident and injury rates are even higher, being the leading cause of death in these age groups. Mortality from trauma in the EU has fallen 20 % in the past 20 years, to a rate of 63.7 per 100,000 in 2010 [3]. This reduction is par…

medicine.medical_specialtyResuscitationSports medicinemedia_common.quotation_subjecteducationMEDLINETraumatologyEmergency NursingCritical Care and Intensive Care MedicineCourse (navigation)Injury preventionHealth caremedicineHumansmedia_common.cataloged_instanceOrthopedics and Sports MedicineEuropean unionmedia_commonCause of deathPatient Care TeamMedical educationTeamworkPatient care teambusiness.industryMajor traumaEmergency Respondersmedicine.diseaseEuropeAnesthesiology and Pain MedicineTraumatologyFamily medicineEmergency MedicineWounds and InjuriesEducation Medical ContinuingSurgeryCardiology and Cardiovascular MedicinebusinessResuscitation
researchProduct

A special case of murder committed by pitchfork

2011

The autors describe a murder case, happened in a rural environment, done with an agricultural instrument with "four peak". The use of agricultural instruments to commit a murder, frequent in the past, nowadays is unusual if not in a rural environment.

Settore MED/43 - Medicina Legalestab wounds pitchfork homicides
researchProduct

Healthcare associated infection: novel strategies and antimicrobial implants to prevent surgical site infection

2010

This report is based on a Hygienist Panel Meeting held at St Anne's Manor, Wokingham on 24–25 June 2009. The panel agreed that greater use should be made of antiseptics to reduce reliance on antibiotics with their associated risk of antibiotic resistance. When choosing an antiseptic for clinical use, the Biocompatibility Index, which considers both the microbiocidal activity and any cytotoxic effects of an antiseptic agent, was considered to be a useful tool. The need for longer and more proactive post-discharge surveillance of surgical patients was also agreed to be a priority, especially given the current growth of day-case surgery. The introduction of surgical safety checklists, such as…

Healthcare associated infectionsmedicine.medical_specialtyProsthesis-Related Infectionsmedicine.drug_classAntisepsisReviewBacterial AdhesionAntibiotic resistanceAnti-Infective AgentsAntisepticmedicineHumansSurgical Wound InfectionProsthesis-Related InfectionAntibiotic prophylaxisIntensive care medicineSuturesbusiness.industryGeneral MedicineAntibiotic ProphylaxisAntimicrobialSurgeryAntimicrobial suturesBiofilmsAnti-Infective Agents LocalSurgerybusinessAnti-Infective AgentsSurgical site infectionSurgical site infection
researchProduct

Metal pins fired from unmodified blank cartridge guns and very small calibre weapons - technical and wound ballistic aspects

1998

Blank cartridge guns are generally regarded as being harmless and are not considered to be firearms in most countries. A comparison of the legal situations in Germany and Austria concerning weapons is given. There have been several reports of serious injuries and even fatalities due to these weapons. Ballistic experiments show that even unmodified blank cartridge guns and very small calibre weapons can fire wire nails and can inflict potentially fatal injuries even at distances of 50 cm. Two serious injuries inflicted by metal pins fired from a blank cartridge gun and a very small calibre weapon are reported. These cases suggest that such weapons should also be considered handguns in the le…

MaleFirearmsEngineeringInjury controlAccident preventionbusiness.industryPoison controlForensic MedicineMiddle AgedPathology and Forensic MedicineCaliberAustriaGermanyForensic engineeringHumansWounds GunshotbusinessBlank cartridgeAgedInternational Journal of Legal Medicine
researchProduct

Äitiys, huostaanotto ja voimaantuminen

2015

This study explores mothers’ experiences of their children’s custody. The empirical data consists of twelve interviews with mothers with a child custody experience. Seven interviews were conducted twice, in years 2004 and 2008. The purpose of the dissertation is three-fold: 1) to clarify the construction of motherhood before and after the custody; 2) to define what kind of support the mothers received after the children had been placed outside home; and 3) to identify promotive and hindering factors for the empowerment of these mothers. As for the method, this phenomenological study drew on qualitative content analysis. This dissertation sheds light on the reasons for child custody, as expr…

wounded(ness)experiencelastensuojeluhuostaanottoempowermentcustodyvanhemmuusmotherhoodvoimaantuminenäitiysäidittukipalvelut
researchProduct