Search results for "annona"

2019

Phytochemical investigations of ethanol root bark and stem bark extracts of Cleistochlamys kirkii (Benth.) Oliv. (Annonaceae) yielded a new benzopyranyl cadinane-type sesquiterpene (cleistonol, 1) alongside 12 known compounds (2–13). The structures of the isolated compounds were established from NMR spectroscopic and mass spectrometric analyses. Structures of compounds 5 and 10 were further confirmed by single crystal X-ray crystallographic analyses, which also established their absolute stereochemical configuration. The ethanolic crude extract of C. kirkii root bark gave 72% inhibition against the chloroquine-sensitive 3D7-strain malaria parasite Plasmodium falciparum at 0.01 μg/mL. The is…

Vasodilator Effects of Liriodenine and Norushinsunine, Two Aporphine Alkaloids Isolated from <i>Annona cherimolia,</i>in Rat Aorta

1995

The effect of two aporphines, liriodenine and norushinsunine, isolated from Annona cherimolia, were studied in the rat aorta in order to examine their mechanism of action. Both alkaloids (10–7–10–4 mol/l) showed relaxant effects on the contractions elicited by 10–6 mol/l noradrenaline (NA) or 80 mmol/l KC1, but, while liriodenine showed a nonspecific relaxant action on both spasmogens, norushinsunine was more potent on KC1-induced contraction. In Ca2+-free medium, both alkaloids (0.1 mmol/l) inhibited the responses elicited by NA, but not those elicited by caffeine. This inhibitory action occurred when the alkaloids were present during the release of the Ca2+ internal stores or during the r…

Cerasodine and Cerasonine:  New Oxoprotoberberine Alkaloids from Polyalthia cerasoides

1997

Two new 7,8-dihydro-8-oxoprotoberberine alkaloids, cerasodine (1) and cerasonine (2), were isolated from the stem bark of Polyalthia cerasoides (Annonaceae).

Acetogenins, Aporphinoids, and Azaanthraquinone from Annona cherimolia Seeds.

1989

We have isolated several known steroids, glycosides, isoquinoline, and azaanthraquinone alkaloids, and five acetogenins belonging to a new group of secondary metabolites, the bis-tetrahydrofuran gamma-lactones, from the seeds of ANNONA CHERIMOLIA. The azaanthraquinone alkaloid isolated was identified as cleistopholine. One new acetogenin is reported here: laherradurine; a second new one was isolated, but its structure has not been determined. The other three: cherimoline, dihydrocherimoline, and asimicine have already been reported.

Diepoxyrollin and Diepomuricanin B:  Two New Diepoxyacetogenins from Rollinia membranacea Seeds

1997

Diepoxyrollin (1) and diepomuricanin B (2), two new Annonaceous acetogenins were isolated from the cytotoxic MeOH extract of the seeds of Colombian Rollinia membranacea. Five others known acetogenins were also isolated, dieporeticanin 1, dieporeticanin 2, diepomuricanin A, rollinone, and sylvaticin. Their structures were elucidated on the basis of spectral data. Compounds 1 and 2 belong to the rare type of diepoxyacetogenins, which are probably precursors of the mono-tetrahydrofuran acetogenins.

New method for the determination of the absolute stereochemistry in antitumoral annonaceous acetogenins

1998

Abstract The absolute configurations at the carbinol centers in several acetogenins were determined through p-bromophenylurethane derivatives and subsequent Mosher ester methodology. This method has been applied on α,α′-dihydroxylated adjacent bis-THF acetogenins with a threo/cis/threo/cis/erythro relative configuration membrarollin (1), a new acetogenin isolated from Rollinia membranacea seeds, rollimembrin (2), membranacin (3) and rolliniastatin-1 (4), and a threo/trans/threo/translerythro relative configuration motrilin (5), squamocin (6), and desacetyluvaricin (7). 1 was found to be the most potent inhibitor of the mammalian mitochondrial complex I.

Tripoxyrollin, a New Epoxy Acetogenin from the Seeds ofRollinia membranacea1

1993

Abstract A new epoxy acetogenin, tripoxyrollin (1), has been isolated from the seeds of the Colombian Annonaceae, Rollinia membranacea. Its structure was elucidated on the basis of spectral data. Biomimetic synthesis of isodesacetyluvaricin (2) from tripoxyrollin (1) suggests its key role in the biogenesis of the adjacent bis-tetrahydrofuran acetogenins.

Nuovi spazi di coltivazione e futuro interessante per l’Annona cherimola

2021

La coltivazione dell’annona in Calabria, sebbene con qualche difficoltà legata alla fisiologia della specie, è possibile con risultati produttivi e qualitativi promettenti. I frutti hanno conquistato il mercato interno spuntando prezzi interessanti per i produttori anche se le superfici coltivate sono ancora piuttosto limitate. L’aumento della domanda commerciale e le caratteristiche qualitative dei frutti lasciano presagire un possibile ampliamento delle coltivazioni.

MENSURA, PROBATIO E GARANZIE CONTRO IL RISCHIO DELLA NAVIGAZIONE, NEL REGIME DEI TRASPORTI PUBBLICI IN ETÀ IMPERIALE

Magazzini, luoghi di sbarco e personale dell’annona della città di Messina in età moderna

2008

Il ruolo dei magazzini del Peculio frumentario di Messina e dei suoi funzionari in epoca moderna è distinto in tre momenti con impostazioni economiche diverse. Nella prima fase (1591-1687) i magazzini sono amministrati in modo sleale nei confronti delle finanze pubbliche e l’annona si indebita nei confronti della stessa élite urbana che esprime i funzionari. Nella seconda, tra la repressione della rivolta antispagnola e l’inizio della monarchia borbonica, il potere centrale riprendere il con trollo sulle classi dirigenti locali anche in campo annonario, e la gestione dei magazzini pubblici acquista rigore e importanza a causa delle proibizioni ai privati di importare direttamente il grano. …