Search results for "bacteri"

showing 10 items of 5466 documents

Pneumococcal HxxHxH triad – Copper(II) interactions – How important is the ‘x’?

2019

Abstract PhtA, a Streptococcus pneumoniae polyhistidine triad protein, which contributes to virulence by interacting with components of the immune system, by being involved in adherence of bacteria and in Zn(II) uptake, contains five copies of the HxxHxH sequence. Since this motif is also present in numerous Cu(II) binding proteins, we decided to focus on the bioinorganic chemistry of copper(II) with three of such PhtA repeats, in order to understand which of the PhtA triads binds Cu(II) with the highest affinity and explain if Cu(II) would be able to outcompete Zn(II) from its native binding site under physiological metal concentrations.

biology010405 organic chemistryChemistryStereochemistryVirulencechemistry.chemical_elementBioinorganic chemistry010402 general chemistrymedicine.disease_causebiology.organism_classification01 natural sciencesDNA-binding proteinCopper0104 chemical sciencesInorganic ChemistryMetalvisual_artStreptococcus pneumoniaeMaterials Chemistrymedicinevisual_art.visual_art_mediumPhysical and Theoretical ChemistryBinding siteBacteriaInorganica Chimica Acta
researchProduct

Molar growth yields ofZymomonas mobilis on glucose after the transition from anaerobic to aerobic continuous growth

1999

An increase in the molar growth yield (Y X/S = 14.3-20.3 g/mol) on glucose (25 mM) was achieved after the transition of Zymomonas mobilis ATCC 29191 from anaerobic to aerobic steady state growth at dilution rates of D = 0.31-0.40 1/h and under oxygen-unlimited conditions. The transfer of anaerobically or aerobically grown steady state cells into a fresh medium resulted in the higher values of Y X/S . A positive correlation was established between biomass and acetaldehyde yield within the range of 5-9 mM acetaldehyde in the medium. An inhibitory effect of the exogenously added acetaldehyde (Kj = 16.7 ± 2.8 mM) on the ATPase activity was observed in vitro, using cell-free extracts of anaerobi…

biologyAcetaldehydeBiomassBioengineeringbiology.organism_classificationApplied Microbiology and BiotechnologyZymomonas mobilisDilutionchemistry.chemical_compoundBiochemistrychemistryYield (chemistry)Steady state (chemistry)Anaerobic exerciseBacteriaBiotechnologyNuclear chemistryActa Biotechnologica
researchProduct

Pheromone-binding proteins of scarab beetles.

1998

: We have characterized Pheromone binding proteins (PBPs) present in the antennae of several species of scarab beetles. In most cases there was only one class of PBP, which was expressed in both sexes. Both Anomala osakana and Popillia japonica possess a single PBP, highly homologous to each other. In each species the same PBP seems to recognize both enantiomers of japonilure, which have opposite biological functions, i.e., the sex Pheromone and the behavioral antagonist (stop signal). The purified PBP of A. osakana binds both enantiomers apparently with the same low affinity. Unexpectedly, these ligands were bound by moth PBPs, which utilize Pheromones with unrelated structures. These find…

biologyAnomala osakanaLigandGeneral Neurosciencebiochemical phenomena metabolism and nutritionbiology.organism_classificationGeneral Biochemistry Genetics and Molecular BiologyChemoreceptor CellsPheromonesColeopteraLow affinityHistory and Philosophy of ScienceBiochemistrySex pheromoneBotanyPopilliapolycyclic compoundsHomologous chromosomebacteriaAnimalsInsect ProteinsPheromone bindingEnantiomerAnnals of the New York Academy of Sciences
researchProduct

The L-tartrate/succinate antiporter TtdT (YgjE) of L-tartrate fermentation in Escherichia coli.

2007

ABSTRACT Escherichia coli ferments l -tartrate under anaerobic conditions in the presence of an additional electron donor to succinate. The carrier for l -tartrate uptake and succinate export and its relation to the general C 4 -dicarboxylate carriers DcuA, DcuB, and DcuC were studied. The secondary carrier TtdT, encoded by the ttdT (previously called ygjE ) gene, is required for the uptake of l -tartrate. The ttdT gene is located downstream of the ttdA and ttdB genes, encoding the l -tartrate dehydratase TtdAB. Analysis of mRNA by reverse transcription-PCR showed that ttdA , ttdB , and ttdT are cotranscribed. Deletion of ttdT abolished growth by l -tartrate and degradation of l -tartrate c…

biologyAntiporterPhysiology and MetabolismSuccinic AcidHeterologousSubstrate (chemistry)Biological TransportTartratebiology.organism_classificationmedicine.disease_causeMicrobiologychemistry.chemical_compoundBiochemistrychemistryBacterial ProteinsDehydrataseFermentationOperonmedicineEscherichia coliFermentationMolecular BiologyEscherichia coliTartratesBacteriaJournal of bacteriology
researchProduct

Utilizing genetically engineered bacteria to produce plant-specific glucosides

2001

Plant-derived glucosides have attracted much attention due to their widespread applications. This class of products is difficult to isolate or to synthesize in pure form because of the resulting low yields. Thus, simple approaches for the generation of such glucosides would be highly beneficial. We purified and characterized a novel glucosyltransferase from plant cell suspension cultures of Rauvolfia serpentina, which showed rather low substrate specificity. We obtained its cDNA and expressed the active recombinant protein in bacteria (Escherichia coli) with excellent plant-specific glucosylation efficiencies. Compared with the plant system, the bacteria delivered the new enzyme, which was …

biologyArbutinBioengineeringbiology.organism_classificationmedicine.disease_causeApplied Microbiology and BiotechnologyEnterobacteriaceaeTransformation (genetics)chemistry.chemical_compoundGlucosidechemistryBiochemistryRauvolfia serpentinabiology.proteinmedicineGlucosyltransferaseEscherichia coliBacteriaBiotechnologyBiotechnology and Bioengineering
researchProduct

Chemical composition and antimicrobial activity of some oleogum resin essential oils from Boswellia spp. (Burseraceae).

2007

The chemical composition of Boswellia carteri (Somalia), B. papyrifera (Ethiopia), B. serrata (India) and B. rivae (Ethiopia) oleogum resin essential oils was investigated using GC-MS to identify chemotaxonomy marker components. Total ion current peak areas gave good approximations to relative concentrations based on GC-MS peak areas. B. carteri and B. serrata oleogum resin oils showed similar chemical profiles, with isoincensole and isoincensole acetate as the main diterpenic components. Both n-octanol and n-octyl acetate, along with the diterpenic components incensole and incensole acetate, were the characteristic compounds of B. papyrifera oleogum resin oil. Hydrocarbon and oxygenated mo…

biologyBacteriaChemistryFungiMicrobial Sensitivity Testsbiology.organism_classificationAntimicrobialGas Chromatography-Mass SpectrometryAnalytical Chemistrylaw.inventionBoswellia sacraAnti-Infective AgentsChemotaxonomylawOils VolatileOrganic chemistryBurseraceaeFood scienceBoswelliaBoswelliaChemical compositionBoswellia papyriferaEssential oilGeneral Environmental ScienceAnnali di chimica
researchProduct

A search for beta-lactamase in chlamydiae, mycoplasmas, planctomycetes, and cyanelles: bacteria and bacterial descendants at different phylogenetic p…

2000

Bacteria from different phylogenetic positions such as chlamydiae, mycoplasmas, planctomycetes and also endosymbiotic murein-containing cyanelles were investigated for the production of beta-lactamases. No beta-lactamase activity was found in bacteria lacking murein such as Chlamydia pneumoniae, Mycoplasma pneumoniae, Pirellula marina and Planctomyces maris. In the murein-containing cyanelles of Cyanophora paradoxa no beta-lactamase activity could be detected.

biologyBacteriaPlanctomycetesChlamydiaeEukaryotaMycoplasmataceaeMycoplasmaPeptidoglycanbiochemical phenomena metabolism and nutritionChlamydophila pneumoniaemedicine.disease_causebiology.organism_classificationMicrobiologybeta-LactamasesMicrobiologyMycoplasma pneumoniaecarbohydrates (lipids)Cell WallChlamydialesmedicineMollicutesbacteriaCyanophora paradoxaBacteriaPhylogenyMicrobiological research
researchProduct

Deoxycholic Acid Methyl Ester — a Novel Bacterial Metabolite of Cholic Acid

1985

Summary Methyl deoxycholate was identified as a novel bacterial metabolite of cholate, produced anaerobically by strains of most saccharolytic Bacteroides species ( B. distasonis, B. eggerthii, B. fragilis, B. incommunis, B. thetaiotaomicron, B. uniformis, B. variabilis, B. vulgatus , and unnamed species). It was also detected with a few strains of Eubacterium and Lactobacillus species. Among 2476 freshly isolated human fecal cultures the frequency of carboxyl group esterification was comparable with that of 7α-dehydroxylation (92 versus 102 cultures). Both activities were, however, lost for unknown reasons after serial transfers. Two of ten mixed fecal cultures tested esterified 3α,7α- or …

biologyBile acidmedicine.drug_classMetaboliteDeoxycholic acidCholic acidbiology.organism_classificationApplied Microbiology and BiotechnologyMicrobiologyMicrobiologychemistry.chemical_compoundfluids and secretionschemistryBiochemistryLactobacillusmedicineEubacteriumBacteroidesEcology Evolution Behavior and SystematicsBacteriaSystematic and Applied Microbiology
researchProduct

Gnotobiotische untersuchungen an SPF-Mäusen im rahmen einer studie zur tumorentwicklung im kolon nach cholezystektomie

1985

Summary The relation between cholecystectomy and colon carcinogenesis has not been fully elucidated. As bacteria may be involved in the carcinogenic process, we investigated the effect of cholecystectomy and dimethylhydrazine (DMH) administration to SPF NMRI mice with regard to tumour genesis and bacterial colonisation of the intestine. It results from this study that cholecystectomy does not influence tumour genesis and that 6–7 months post operationem and DMH administration tumours and bacteria originally not found in the animals develop: Clostridia, eubacteria spec, which cannot be differentiated and E. lentum. Theses changes appear in group II of mice (laparotomy and DMH) and group III …

biologyBile acidmedicine.drug_classRatónmedicine.medical_treatmentImmunologybiology.organism_classificationMicrobiologyClostridiaClostridiumDimethylhydrazinemedicineCholecystectomyBacteriaCarcinogenZentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology
researchProduct

Prevalence of Listeria sp. in droppings from urban rooks (Corvus frugilegus)

1997

Droppings from 112 urban rooks (Corvus frugilegus) were cultured for the presence of Listeria sp. Overall, 46% of rooks sampled harboured one or more Listeria species. Of all birds examined, 33%, 24% and 8%, respectively, were infected with Listeria monocytogenes, Listeria innocua and Listeria seeligeri. Differentiation of L. monocytogenes and L. seeligeri carried out by several phenotypic typing methods proved the diversity of strains and the major role of rooks which widely contribute to spreading this bacteria in our environment. The results also suggest that the ability to recover specific Listeria strains from the same sample is at least partially dependent on the methodology. These fi…

biologyBird DiseasesCorvus frugilegusGeneral Medicinemedicine.disease_causebiology.organism_classificationApplied Microbiology and BiotechnologyMicrobiologyListeria speciesBirdsFecesListeria monocytogenesbiology.animalPrevalencemedicineListeriaAnimalsListeriosisListeria seeligeriTypingSerotypingListeria spBacteriaBiotechnologyJournal of Applied Microbiology
researchProduct