Search results for "boron"

showing 10 items of 352 documents

A Rapid and Sensitive Strip-Based Quick Test for Nerve Agents Tabun, Sarin, and Soman Using BODIPY-Modified Silica Materials

2016

Test strips that in combination with a portable fluorescence reader or digital camera can rapidly and selectively detect chemical warfare agents (CWAs) such as Tabun (GA), Sarin (GB), and Soman (GD) and their simulants in the gas phase have been developed. The strips contain spots of a hybrid indicator material consisting of a fluorescent BODIPY indicator covalently anchored into the channels of mesoporous SBA silica microparticles. The fluorescence quenching response allows the sensitive detection of CWAs in the mu g m(-3) range in a few seconds.

Boron CompoundsSarinSilicon dioxideSomanAnalytical chemistrynerve gases010402 general chemistry01 natural sciencesCatalysischemistry.chemical_compoundSomanQUIMICA ANALITICAmedicineChemical Warfare AgentsTabunNerve agenthybrid sensor materialsChromatography010405 organic chemistryOrganic ChemistryQUIMICA INORGANICAGeneral ChemistrySilicon DioxideFluorescenceSarinOrganophosphates0104 chemical scienceschemistrychemical warfare agentstest strip analysisProthrombin TimefluorescenceBODIPYMesoporous materialNerve Agentsmedicine.drug
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Near-infrared emitting fluorescent homobimetallic gold(I) complexes displaying promising in vitro and in vivo therapeutic properties

2021

International audience; Boron neutron capture therapy (BNCT) has the potential to specifically destroy tumor cells without damaging the tissues infiltrated by the tumor. BNCT is a binary treatment method based on the combination of two agents that have no effect when applied individually: 10B and thermal neutrons. Exclusively, the combination of both produces an effect, whose extent depends on the amount of 10B in the tumor but also on the organs at risk. It is not yet possible to determine the 10B concentration in a specific tissue using non-invasive methods. At present, it is only possible to measure the 10B concentration in blood and to estimate the boron concentration in tissues based o…

Boron Compoundsinorganic chemicalsCell SurvivalInfrared RaysAntineoplastic Agents01 natural sciencesMiceStructure-Activity Relationship03 medical and health sciencesOptical imagingCoordination ComplexesIn vivoDrug DiscoveryTumor Cells CulturedAza-bodipyAnimalsHumans[CHIM]Chemical SciencesNir fluorescenceComputingMilieux_MISCELLANEOUSCell ProliferationFluorescent Dyes030304 developmental biologyPharmacologyAza CompoundsMice Inbred BALB C0303 health sciencesDose-Response Relationship DrugMolecular Structure010405 organic chemistryChemistryOptical ImagingOrganic ChemistryNear-infrared spectroscopyNeoplasms ExperimentalGeneral MedicineFluorescenceIn vitro3. Good health0104 chemical sciencesBiophysicsGoldDrug Screening Assays AntitumorCancer cell lines
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BODIPY-phosphane as a versatile tool for easy access to new metal-based theranostics

2012

A new BODIPY-phosphane was synthesized and proved to be a versatile tool for imaging organometallic complexes. It also led to easy access to a new family of theranostics, featuring gold, ruthenium and osmium complexes. The compounds' cytotoxicity was tested on cancer cells, and their cell uptake was followed by fluorescence microscopy in vitro.

Boron Compoundsinorganic chemicalsCell SurvivalPhosphinesINHIBITIONchemistry.chemical_elementGOLD COMPOUNDSRutheniumInorganic ChemistryMetalchemistry.chemical_compoundGold CompoundsPOLYPYRIDINE COMPLEXESCoordination ComplexesCHEMISTRYCell Line TumorFluorescence microscopeHumansOrganic chemistryOsmiumCytotoxicityAGENTSMicroscopy ConfocalChemistryOsmiumCombinatorial chemistryRutheniumMetalsvisual_artPHOTOPHYSICAL PROPERTIESCancer cellvisual_art.visual_art_mediumMODESGoldBODIPYDYESBEHAVIOR
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Gold( i )–BODIPY–imidazole bimetallic complexes as new potential anti-inflammatory and anticancer trackable agents

2017

International audience; Two new gold(I)–BODIPY–imidazole based trackable therapeutic bimetallic complexes have been synthesized and fully characterized. They display strong antiproliferative properties on several types of cancers including colon, breast, and prostate and one of them presents a significant anti-inflammatory effect. Additionally, the two compounds could be visualised in vitro by confocal microscopy in the submicromolar range.

Boron Compoundsmedicine.drug_classStereochemistryAnti-Inflammatory AgentsAntineoplastic Agents[SDV.CAN]Life Sciences [q-bio]/Cancer010402 general chemistry01 natural sciences[ CHIM ] Chemical SciencesAnti-inflammatorylaw.invention[ SDV.CAN ] Life Sciences [q-bio]/CancerInorganic Chemistrychemistry.chemical_compoundConfocal microscopylawCoordination ComplexesCell Line TumorDrug DiscoverymedicineImidazoleHumans[CHIM]Chemical SciencesBimetallic stripCell ProliferationFluorescent Dyes010405 organic chemistryChemistryDrug discoveryImidazolesIn vitro0104 chemical sciences3. Good healthGoldBODIPY
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ChemInform Abstract: Electrochemical Amination of Less-Activated Alkylated Arenes Using Boron-Doped Diamond Anodes.

2016

Boron doped diamondChemistryInorganic chemistryGeneral MedicineAlkylationElectrochemistryAminationAnodeChemInform
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Influence of the Nature of Boron‐Doped Diamond Anodes on the Dehydrogenative Phenol‐Phenol Cross‐Coupling

2019

Boron doped diamondCoupling (electronics)chemistry.chemical_compoundMaterials sciencechemistryElectrochemistryPhenolElectrochemistryPhotochemistryCatalysisAnodeChemElectroChem
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Use of Boron‐Doped Diamond Electrodes in Electro‐Organic Synthesis

2019

Boron doped diamondElectrode materialMaterials sciencebusiness.industryElectrochemistryCatalysischemistry.chemical_compoundSemiconductorchemistryChemical engineeringElectrodeElectrochemistryOrganic synthesisbusinessChemElectroChem
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Frontispiece: The “Green” Electrochemical Synthesis of Periodate

2020

Boron doped diamondElectrolysischemistry.chemical_compoundMaterials sciencechemistrylawInorganic chemistryPeriodateGeneral ChemistryFlow chemistryElectrochemistryCatalysislaw.inventionAngewandte Chemie International Edition
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Anodic coupling of guaiacol derivatives on boron-doped diamond electrodes.

2011

The anodic treatment of guaiacol derivatives on boron-doped diamond electrodes (BDD) provides a direct access to nonsymmetrical biphenols, which would require a multistep sequence by conventional methods. Despite the destructive nature of BDD anodes they can be exploited for chemical synthesis.

Boron doped diamondchemistry.chemical_compoundchemistryOrganic ChemistryElectrodeInorganic chemistryCoupling (piping)GuaiacolPhysical and Theoretical ChemistryDiamond electrodesBiochemistryChemical synthesisAnodeOrganic letters
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A versatile metathesis reaction for the formation of labile bonds between group 13 and group 15 atoms.

2003

Boron groupMain group elementGroup (periodic table)ChemistryEnvironmental chemistryPolymer chemistrySalt metathesis reactionGeneral ChemistryMetathesisCatalysisAngewandte Chemie (International ed. in English)
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