Search results for "causality"
showing 10 items of 258 documents
Comparison of Causality Network Estimation in the Sensor and Source Space: Simulation and Application on EEG
2021
The usage of methods for the estimation of the true underlying connectivity among the observed variables of a system is increasing, especially in the domain of neuroscience. Granger causality and similar concepts are employed for the estimation of the brain network from electroencephalogram (EEG) data. Also source localization techniques, such as the standardized low resolution electromagnetic tomography (sLORETA), are widely used for obtaining more reliable data in the source space. In this work, connectivity structures are estimated in the sensor and in the source space making use of the sLORETA transformation for simulated and for EEG data with episodes of spontaneous epileptiform discha…
On the interpretability and computational reliability of frequency-domain Granger causality
2017
This Correspondence article is a comment which directly relates to the paper “A study of problems encountered in Granger causality analysis from a neuroscience perspective” (Stokes and Purdon, 2017). We agree that interpretation issues of Granger causality (GC) in neuroscience exist, partially due to the historically unfortunate use of the name “causality”, as described in previous literature. On the other hand, we think that Stokes and Purdon use a formulation of GC which is outdated (albeit still used) and do not fully account for the potential of the different frequency-domain versions of GC; in doing so, their paper dismisses GC measures based on a suboptimal use of them. Furthermore, s…
Critical comments on EEG sensor space dynamical connectivity analysis
2019
Many different analysis techniques have been developed and applied to EEG recordings that allow one to investigate how different brain areas interact. One particular class of methods, based on the linear parametric representation of multiple interacting time series, is widely used to study causal connectivity in the brain. However, the results obtained by these methods should be interpreted with great care. The goal of this paper is to show, both theoretically and using simulations, that results obtained by applying causal connectivity measures on the sensor (scalp) time series do not allow interpretation in terms of interacting brain sources. This is because (1) the channel locations canno…
Do-search -- a tool for causal inference and study design with multiple data sources
2020
Epidemiologic evidence is based on multiple data sources including clinical trials, cohort studies, surveys, registries, and expert opinions. Merging information from different sources opens up new possibilities for the estimation of causal effects. We show how causal effects can be identified and estimated by combining experiments and observations in real and realistic scenarios. As a new tool, we present do-search, a recently developed algorithmic approach that can determine the identifiability of a causal effect. The approach is based on do-calculus, and it can utilize data with nontrivial missing data and selection bias mechanisms. When the effect is identifiable, do-search outputs an i…
Local Granger causality
2021
Granger causality is a statistical notion of causal influence based on prediction via vector autoregression. For Gaussian variables it is equivalent to transfer entropy, an information-theoretic measure of time-directed information transfer between jointly dependent processes. We exploit such equivalence and calculate exactly the 'local Granger causality', i.e. the profile of the information transfer at each discrete time point in Gaussian processes; in this frame Granger causality is the average of its local version. Our approach offers a robust and computationally fast method to follow the information transfer along the time history of linear stochastic processes, as well as of nonlinear …
Causal Effect Identification from Multiple Incomplete Data Sources: A General Search-Based Approach
2021
Causal effect identification considers whether an interventional probability distribution can be uniquely determined without parametric assumptions from measured source distributions and structural knowledge on the generating system. While complete graphical criteria and procedures exist for many identification problems, there are still challenging but important extensions that have not been considered in the literature. To tackle these new settings, we present a search algorithm directly over the rules of do-calculus. Due to generality of do-calculus, the search is capable of taking more advanced data-generating mechanisms into account along with an arbitrary type of both observational and…
Estimation of causal effects with small data in the presence of trapdoor variables
2021
We consider the problem of estimating causal effects of interventions from observational data when well-known back-door and front-door adjustments are not applicable. We show that when an identifiable causal effect is subject to an implicit functional constraint that is not deducible from conditional independence relations, the estimator of the causal effect can exhibit bias in small samples. This bias is related to variables that we call trapdoor variables. We use simulated data to study different strategies to account for trapdoor variables and suggest how the related trapdoor bias might be minimized. The importance of trapdoor variables in causal effect estimation is illustrated with rea…
Synergetic and redundant information flow detected by unnormalized Granger causality: application to resting state fMRI
2015
Objectives: We develop a framework for the analysis of synergy and redundancy in the pattern of information flow between subsystems of a complex network. Methods: The presence of redundancy and/or synergy in multivariate time series data renders difficult to estimate the neat flow of information from each driver variable to a given target. We show that adopting an unnormalized definition of Granger causality one may put in evidence redundant multiplets of variables influencing the target by maximizing the total Granger causality to a given target, over all the possible partitions of the set of driving variables. Consequently we introduce a pairwise index of synergy which is zero when two in…
Surrogate outcomes and transportability
2019
Identification of causal effects is one of the most fundamental tasks of causal inference. We consider an identifiability problem where some experimental and observational data are available but neither data alone is sufficient for the identification of the causal effect of interest. Instead of the outcome of interest, surrogate outcomes are measured in the experiments. This problem is a generalization of identifiability using surrogate experiments and we label it as surrogate outcome identifiability. We show that the concept of transportability provides a sufficient criteria for determining surrogate outcome identifiability for a large class of queries.
La Comprensión Asíncrona de las Emociones Básicas: un Estudio Longitudinal con Niños de 3 a 5 Años
2021
El presente estudio tiene como finalidad explorar la trayectoria evolutiva de la comprensión de cuatro emociones en niños de tres a cinco años. Sabemos que los niños identifican las expresiones faciales y después entienden la causa de las emociones, pero ¿las emociones se comprenden a la vez, en el mismo momento evolutivo? Para llevar a cabo este estudio se evaluó de forma longitudinal a un grupo de 103 niños y niñas entre los 3 y los 5 años. A través del Test de Comprensión Emocional se midieron los componentes de identificación de la expresión emocional y el conocimiento de la causa de cuatro emociones –tristeza, alegría, enfado y miedo– a lo largo de los tres años. Los resultados confirm…