Search results for "characterization"

showing 10 items of 1054 documents

The structure and biosynthesis of heinamides A1-A3 and B1-B5, antifungal members of the laxaphycin lipopeptide family.

2021

Laxaphycins are a family of cyclic lipopeptides with synergistic antifungal and antiproliferative activities. They are produced by multiple cyanobacterial genera and comprise two sets of structurally unrelated 11- and 12-residue macrocyclic lipopeptides. Here, we report the discovery of new antifungal laxaphycins from Nostoc sp. UHCC 0702, which we name heinamides, through antimicrobial bioactivity screening. We characterized the chemical structures of eight heinamide structural variants A1-A3 and B1-B5. These variants contain the rare non-proteinogenic amino acids 3-hydroxy-4-methylproline, 4-hydroxyproline, 3-hydroxy-d-leucine, dehydrobutyrine, 5-hydroxyl beta-amino octanoic acid, and O-c…

BIOCHEMICAL-CHARACTERIZATIONNostocGENE-CLUSTER116 Chemical sciencesALGA ANABAENA-LAXAaminohapotPRODUCT01 natural sciencesBiochemistryCELL-PROLIFERATIONbiosynteesi03 medical and health scienceschemistry.chemical_compoundLipopeptidesBiosynthesisGene clusterPhysical and Theoretical ChemistryHYDROXYPROLINE030304 developmental biologyantimikrobiset yhdisteetchemistry.chemical_classificationWhole genome sequencing0303 health sciencesbiology010405 organic chemistryOrganic ChemistryLipopeptidePEPTIDESCYANOBACTERIAbiology.organism_classification3. Good health0104 chemical sciencesAmino acidEnzymeBiochemistrychemistrypeptiditHeterologous expressionCYCLIC LIPOPEPTIDESINHIBITORSOrganicbiomolecular chemistry
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Preparation and Characterization of P2 BCh Ring Systems (Ch=S, Se) and Their Reactivity with N-Heterocyclic Carbenes

2018

Four-membered rings with a P2BCh core (Ch = S, Se) have been synthesized via reaction of phosphinidene chalcogenide (Ar*P=Ch) and phosphaborene (Mes*P=BNR2). The mechanistic pathways towards these rings are explained by detailed computational work that confirmed the preference for the formation of P–P, not P–B, bonded systems, which seems counterintuitive given that both phosphorus atoms contain bulky ligands. The reactivity of the newly synthesized heterocycles, as well as that of the known (RPCh)n rings (n = 2, 3), was probed by the addition of Nheterocyclic carbenes, which revealed that all investigated compounds can act as sources of low-coordinate phosphorus species. peerReviewed

BOND COVALENT RADIIChalcogenidePHOSPHINIDENE ADDUCTSSULFURchemistry.chemical_element010402 general chemistryRing (chemistry)ION ABSTRACTION01 natural sciencesMedicinal chemistryCatalysischemistry.chemical_compoundELEMENTSmain-group heterocyclesReactivity (chemistry)N-heterocyclic carbenesMETHYLENEPHOSPHINEta116epäorgaaniset yhdisteetphosphinidene chalcogenidesheterocycleskemiallinen synteesiphosphaborenes010405 organic chemistryPhosphorusOrganic ChemistryGeneral ChemistryREAGENT0104 chemical sciencesCharacterization (materials science)PHOSPHORUSchemistryPhosphinideneinorganic compoundsSULFURIZATIONchemical synthesisX-RAY-STRUCTUREChemistry - A European Journal
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Dental disease and dietary isotopes of individuals from St Gertrude Church cemetery, Riga, Latvia.

2018

This research explores oral health indicators and stable carbon and nitrogen isotope data to explore diet, and differences in diet, between people buried in the four different contexts of the St Gertrude Church cemetery (15th– 17th centuries AD): the general cemetery, two mass graves, and a collective mass burial pit within the general cemetery. The main aim is to assess whether people buried in the mass graves were rural immigrants, or if they were more likely to be the victims of plague (or another epidemic) who lived in Riga and its suburbs. The data produced (from dental disease assessments and isotope analyses) were compared within, as well as between, the contexts. Most differences em…

Bacterial DiseasesTeethPhysiologyImmigrationDigestive PhysiologyPrevalencelcsh:MedicineMarine and Aquatic SciencesOral DiseasesCariesMedicine and Health Sciences0601 history and archaeologyCemeteriesMarine Fishlcsh:Sciencemedia_commonCarbon IsotopesMultidisciplinaryCalculus060102 archaeologyStomatognathic DiseasesMarine fishEukaryota06 humanities and the artsGeographyInfectious DiseasesPhysical SciencesVertebratesAnatomyResearch Articlemedia_common.quotation_subjectOral MedicineMarine BiologyOral healthPlague (disease)Research and Analysis MethodsOral and maxillofacial pathologymedicineHumansAnimalsDentitionChemical CharacterizationPeriodontal DiseasesNutritionIsotope Analysis060101 anthropologyNitrogen Isotopeslcsh:ROrganismsBiology and Life Sciencesmedicine.diseaseLatviaDietFishJawEarth Scienceslcsh:QRural areaDigestive SystemHeadMathematicsDemographyPloS one
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The characterization of the capability of a balance

1996

A survey is given on important standardized definitions by which the capability of balances may be characterized. Some modifications are proposed with regard to the use of mass sensors for the continuous determination of mass variations. An important supplement is the ‘relative resolution’ introduced by Jenemann. Optimum values are presented.

Balance (accounting)Resolution (mass spectrometry)Computer scienceAnalytical chemistrySensitivity (control systems)Stability (probability)Reliability engineeringCharacterization (materials science)Journal of Thermal Analysis
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Optimización de las propiedades de emulsión de betún para la estabilización de balasto

2017

Ballasted track, while providing economical and practical advantages, is associated with high costs and material consumption due to frequent maintenance. More sustainable alternatives to conventional ballasted trackbeds should therefore aim at extending its durability, particularly considering ongoing increases in traffic speed and loads. In this regard, the authors have investigated a solution consisting of bitumen stabilised ballast (BSB), designed to be used for new trackbeds as well as in reinforcing existing ones. This study presents the idea behind the technology and then focuses on a specific part of its development: the optimisation of bitumen emulsion properties and dosage in relat…

BallastEngineeringCharacterizationPermeabilidad0211 other engineering and technologiesflowability02 engineering and technologyTrack (rail transport)CaracterizaciónPermeabilityDurabilityDeformación021105 building & constructionlcsh:TA401-492medicineÁridos; Caracterización; Permeabilidad; Deformación; DurabilidadGeneral Materials SciencecharacterizationProcess engineeringMaterials of engineering and construction. Mechanics of materials021101 geological & geomatics engineeringAggregateAggregate (composite)trackbed durabilityEconomies of agglomerationbusiness.industryrailway trackbeddeformationStiffnessBuilding and ConstructionStructural engineeringAggregate; Characterization; Permeability; Deformation; DurabilityDurabilityDeformationBitumen stabilised ballastaggregate13. Climate actionMechanics of MaterialsAsphaltViscosity (programming)TA401-492durabilitylcsh:Materials of engineering and construction. Mechanics of materialsmedicine.symptompermeabilitybitumen emulsionbusinessDurabilidadÁridos
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Mechanical Characterization of a Basalt Fabric for TRM Composites: Role of the Test Variables

2021

Textile reinforced mortar (TRM) materials are currently receiving great attention for the strengthening of reinforced concrete and masonry structural elements. Mortars with different strength classes have been coupled with different kind of synthetic fabrics, such as carbon, glass, steel, PBO. Recently natural fibres and, in particular, basalt fibres are receiving increasing interest since they proved to be a promising alternative to the most common synthetic fabrics, thanks to the reduced production costs and the consequent benefits in terms of environmental impact. This paper presents an experimental investigation comprising forty-one monotonic tensile tests on textile strips made with a …

BasaltMaterials scienceDigital image correlation (DIC)Experimental investigationTRM compositesBasalt textileComposite materialTensile testsCharacterization (materials science)
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Experimental characterization of a proton exchange membrane fuel-cell for hybrid electric pedal assisted cycles

2017

This paper presents a feasibility study on the prototyping of a hybrid EPAC (Electric Pedal Assisted Cycle) through an FC-B-UC (Fuel Cell — Battery — Ultra-Capacitors) power system. Aim of this work is the characterization of a PEMFC (Proton Exchange Membrane Fuel Cell) in order to confirm its theoretical performances and to verify the possibility of its installation on an e-bike.

Battery (electricity)Materials science020209 energyNuclear engineering020208 electrical & electronic engineeringProton exchange membrane fuel cell02 engineering and technologylaw.inventionCharacterization (materials science)Electric power systemCapacitorlaw0202 electrical engineering electronic engineering information engineeringFuel cells2017 IEEE 6th International Conference on Renewable Energy Research and Applications (ICRERA)
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Modelling, simulation and characterization of Li-Ion battery cell

2019

The decarbonizing process of the transportation system and the spread of unplanned renewables energy source, such as photovoltaic and wind energies, brought the constant need of ever more efficient energy storage technologies. Among these technologies, batteries, particularly the li-ion chemistry, are widely used in automotive and energy storage applications. For an optimized management of the cell it is advisable to have models that can accurately describe cell behaviour. In this paper a battery model for performance simulation in automotive application is identified. The main shapes of battery cells with their own advantages and disadvantages are shown, and a roundup of the best available…

Battery (electricity)li-ionbusiness.industryPhotovoltaic systemProcess (computing)Automotive industrymodelingcellSettore ING-IND/32 - Convertitori Macchine E Azionamenti ElettricisimulationEnergy storageAutomotive engineeringRenewable energySettore ING-IND/31 - ElettrotecnicabatterycharacterizationbusinessEnergy sourceEfficient energy use2019 IEEE 5th International forum on Research and Technology for Society and Industry (RTSI)
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Experimental investigation and characterization of innovative bifacial silicon solar cells

2019

The interest towards bifacial PV technology has increased over the last years, due to its potential capability of obtaining higher efficiencies with respect to traditional monofacial cells. Thus, the aim of this work is to present an experimental investigation on an innovative photovoltaic technology, such as the bifacial solar cells based on monocrystalline substrate. This analysis is mainly based on the determination of the current density/voltage, power density/voltage, External Quantum Efficiency (EQE) and Laser Beam Induced Current (LBIC) characterization. Interesting results are presented and discussed, demonstrating that the bifacial silicon solar cells can be a very promising techno…

Bifacial solar cellSettore ING-IND/31 - ElettrotecnicaPERTSettore ING-IND/32 - Convertitori Macchine E Azionamenti ElettriciLBICElectrical characterizationSettore ING-INF/01 - Elettronica
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The Extracellular Vesicles of the Helminth Pathogen, Fasciola hepatica : Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis

2015

Extracellular vesicles (EVs) released by parasites have important roles in establishing and maintaining infection. Analysis of the soluble and vesicular secretions of adult Fasciola hepatica has established a definitive characterisation of the total secretome of this zoonotic parasite. Fasciola secretes at least two sub-populations of EVs that differ according to size, cargo molecules and site of release from the parasite. The larger EVs are released from the specialised cells that line the parasite gastrodermus and contain the zymogen of the 37 kDa cathepsin L peptidase that performs a digestive function. The smaller exosome-like vesicle population originate from multivesicular bodies with…

Biochemistry & Molecular BiologyBIOCHEMICAL-CHARACTERIZATIONHelminth proteinHOST FIBRINOLYTIC SYSTEMPopulationSTATISTICAL-MODELBINDING PROTEINBiochemistryExosomeAnalytical ChemistryproteomicsLIVER FLUKEFasciola hepaticaParasite hostingAnimalsexosomeeducationMolecular BiologyhelminthTRICHOMONAS-VAGINALISSyncytiumeducation.field_of_studyFasciolabiologyResearchGene Expression ProfilingGene Expression Regulation DevelopmentalHelminth ProteinsIN-VITROFasciola hepaticaExtracellular vesiclesbiology.organism_classificationCell biologysecretomeCATHEPSIN L1transcriptomeLEUCINE AMINOPEPTIDASEBiogenesisSCHISTOSOMA-MANSONIMolecular & Cellular Proteomics
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