Search results for "choline"

Chemical composition, antioxidant and anticholinesterase activity of the essential oil of algerian cachrys sicula L

2021

In this work, in order to explore a new Algerian medicinal plant used in traditional medicine, the essential oil of the leaves of Cachrys sicula L. (Apiaceae) collected from Algeria, obtained by hydrodistillation, was analyzed by GC/MS. Thirty-two compounds were identified accounting for 98.6% of the total oil, which is characterized by a high content of monoterpene hydrocarbons (74.8%). The main constituents of the essential oil were β-pinene (17.9%), sabinene (17.8%), myrcene (12%), and α-pinene (11.4%). In vitro antioxidant activity of the essential oil was assayed by three methods, namely ABTS•+, metal chelating, and DPPH• assays. The antioxidant activity of the oil was higher in the AB…

THE EFFECTS OF MUSCARINIC AGONISTS AND ANTAGONISTS ON ACETYLCHOLINE RELEASE FROM PERIPHERAL CHOLINERGIC NERVES IN THE ABSENCE AND PRESENCE OF A CHOLI…

1980

Uptake of Acetylcholine by Bean Hypocotyl Hooks

1978

Summary The uptake of acetylcholine by etiolated hypocotyl hooks of beans ( Phaseolus vulgaris L.) is influenced by light and the pH-value of the incubation medium. Acetylcholine is hydrolysed up to 90 % during the uptake. The hydrolysis is inhibited by pH-value lower than 6.0 and by eserine, an inhibitor of the acetylcholinesterase. The high amount of hydrolysis is a serious problem in experiments involving acetylcholine and necessitates the inclusions of adequate controls without which direct effects of acetylcholine cannot be distinguished from reactions of its metabolic products.

Use of Antibodies in the Research on Muscarinic Receptor Subtypes

2016

Elimination of Parathion by Hemoperfusion in Severe E 605 ForteR Intoxication in Vivo

1978

Severe parathion (P) intoxication results in complete inhibition of cholinesterase activity and toxic accumulation of acetylcholine. Besides these well known biochemical changes, there is evidence of direct toxic effects on the cardio-vascular system which may prove fatal due to an excess of P.

Introduction: The non-neuronal cholinergic system in humans

2003

Cellular Acetylcholine Receptor Expression in the Brain of Patients with Alzheimer’s and Parkinson’s Dementia

1995

Binding studies and receptor autoradiography reveal the overall changes of acetylcholine receptors (AChR) in Alzheimer’s and Parkinson’s dementia cortices.2,5 A detailed account of these changes requires a study of neurochemical phenotype of individual neurons as basic elements of networks constituting the substrate of cortical functions.4 Examples will be given for cell-type specific AChR localization in normal and diseased human cerebral cortex.

1996

18:2Δ 9c,12t and 18:2 Δ9t,12c are present in our diet, as result of heat treatment of vegetable oils. A nutritional study was carried out in order to obtain more precise information on the conversion of these two isomers into long chain polyunsaturated fatty acids (PUFA) by rat tissues. This in vivo study performed using rat fed with small quantities of mono trans linoleic acid isomers (0.6% of total energy) showed that 18:2 Δ9c,12t was converted into 20:4 Δ5c,8c,11c,14t while 18:2 Δ9t,12c was only slightly converted into 20:4 Δ5c,8c,11t,14c. Furthermore 18:2 Δ9t,12c was preferentially elongated into 20:2 Δ11t,14c. Each C20 metabolite of these mono trans 18:2 isomers was isolated as methyl …

Influence of functionalization on interaction and drug release from α,β-polyaspartylhydrazide derivatives to a biomembrane model: evaluation by diffe…

2004

Abstract A comparative study on the ability of various polymers to interact with a biomembrane model was carried out by differential scanning calorimetry (DSC). The investigated samples were a water soluble polymer, the α,β-polyaspartylhydrazide (PAHy) and its derivatives containing polyethylene glycol (PEG2000) (sample PAHy–PEG2000), or hexadecylamine (C16) (sample PAHy–C16) or both compounds (sample PAHy–PEG2000–C16). Some samples are able to arrange themselves as micellar structures and to interact potentially with the membrane surface so as to favor the release of the drug near the target membrane and consequently to improve drug adsorption processes. First, the interaction of all polym…

Analysis of adsorption of phospholipids at the 1,2-dichloroethane/water interface by electrochemical impedance spectroscopy: A study of the effect of…

2007

Abstract The adsorption behaviour of a series of phosphatidylcholines (PCs) with saturated carbon chains of different length (DLPC, DPPC, DSPC, DAPC, and DBPC) at the electrified 1,2-dichloroethane/water interface was studied by measuring electrochemical impedance spectroscopy at the polarized interface. Two different trends in the interfacial capacitance were observed for any of the PCs the capacity dependence on the applied potential: strong adsorption occurs at negative potential with a marked decrease of C ( E ); increase of capacity is observed at positive potentials. It is demonstrated that the interfacial lipid adsorption was dependent on phospholipid concentration, applied potential…