Search results for "derivati"

The sunset of Gortyn: amphorae in 7th –8th centuries AD

2014

Gortyn (A. Di Vita [ed.] 2000-01), some new contexts, more delimited and reliable, allow us to define better circulation, developments, and local use of amphorae in the last periods of urban life of the Cretan city. Two contexts of the mid-late 7th and late 7th-8th centuries are briefly analysed, coming from different quarters of the town (the Old Agora and the Early Byzantine houses near the “Praetorium”), and resulting from different formative processes, which could represent the circulation trends just before, and in the re-occupation phase after the earthquake that dismembered the Late Roman urban layout at the end of the 7th/early 8th century. They display a variety of imports from tra…

Assessment of coronary artery bypass grafts: value of different breath-hold MR imaging techniques.

1999

Our aim was to evaluate the patency of coronary artery bypass grafts and to detect graft stenosis using different breath-hold MR imaging techniques.Twenty-two patients with 59 grafts (14 internal mammary artery grafts and 45 saphenous vein grafts) and 76 distal anastomoses (singular and sequential grafts) were studied using a 1.5-T scanner. A two-dimensional T2-weighted breath-hold half-Fourier acquisition single-shot turbo spin echo (HASTE) sequence and a three-dimensional breath-hold contrast-enhanced MR angiography sequence (fast imaging with steady-state free precession) were performed. For MR angiography, a bolus of 20 ml of gadopentetate dimeglumine was used. Time delay for contrast i…

Analytical technique for studying the structure of glycoprotein N-glycans

1993

Abstract The aim of this study was to develop an analytical strategy for the structural analysis of glycoprotein N-glycans by combining several sensitive methods without any elaborate equipment. The following consecutive steps were optimized and applied: (1) immobilization of glycopeptide N-glycosidase F (EC 3.2.2.18) on several polymeric and a silica support, the latter giving a maximum binding capacity of 11.3% of starting activity; (2) lectin affinity chromatography was miniaturized using Mobitec columns of volume 200 μl; the binding capacity of glycoproteins on concanavalin A and wheat germ agglutinin columns was in the range 0.5–1 μg; (3) N-linked oligosaccharides were isolated from co…

Zur Gelpermeationschromatographie in organischen Lösungsmitteln

1965

Die Gelpermeationschromatographie hat sich vor allem mittels der Sephadexgele fur die Trennung polymerhomologer wasserloslicher Makromolekule als sehr erfolgreich erwiesen. Die Trennung nur in organischen Losungsmitteln loslicher Polymerer ist erst in jungster Zeit gelungen, wobei vernetzte Polystyrol-, Polymethacrylat- und Dextranderivatgele benutzt werden. Der Mechanismus dieses chromatographischen Prozesses wird untersucht. Ein Vergleich dieses Vorganges, bei dem das Polymere nur in einer Phase vorliegt, mit den klassischen Methoden, die mit Auftrennung in zwei Phasen arbeiten, wird durchgefuhrt. Insbesondere werden die Methoden der Dreiecks-Fallungsfraktionierung, der Kolonnentechnik mi…

Synthesis of Enaminones-Based Benzo[d]imidazole Scaffold: Characterization and Molecular Insight Structure

2020

(E)-1-(1H-Benzo[d]imidazol-2-yl)-3-(dimethylamino)prop-2-en-1-one 2 was synthesized by one-pot synthesis protocol of 2-acetyl benzo[d]imidazole with dimethylformamide dimethylacetal (DMF-DMA) in xylene at 140 &deg

BODIPY dyes functionalized with 2-(2-dimethylaminophenyl)ethanol moieties as selective OFF–ON fluorescent chemodosimeters for the nerve agent mimics …

2014

[EN] Two OFF-ON fluorescent chemodosimeters based on a BODIPY core for the detection of nerve agent mimics have been synthesized. Their reactivity towards diethylcyanophosphonate (DCNP) and diisopropylfluorophosphate (DFP) has been tested in organic and aqueous phase. These chemodosimeters selectively detect the nerve agent mimics with good LODs. The chemodosimeters hold their sensing properties on solid supports, allowing the preparation of a hand held sensing kit. The sensing in solid-liquid phase has been demonstrated. The X-ray structure of compound 2 has been resolved.

2017

The energy levels of the HOMO/LUMO Frontier orbitals and the electronic properties of phthalocyanine macrocycles can be tuned by the introduction of substituents. Starting from tetrafluorophthalonitrile, we studied the substitution of fluorine atoms by (2-thienyl)ethoxy moieties. An optimization of the experimental conditions (nature and stoichiometry of the alcohol and base, temperature) allowed us to obtain the monoalkoxy derivative with a very good yield. It was fully characterized using 19F and 1H NMR spectroscopies, thermal analysis and X-ray diffraction on single crystals. Then, the corresponding zinc phthalocyanine was synthesized, characterized by means of 19F and 1H NMR spectroscop…

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)-s-triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Sign…

2022

Here, we synthesized a newseries of mono- and bis(dimethylpyrazolyl)-s-triazine derivatives. The synthetic methodology involved the reaction of different mono- and dihydrazinyl-s-triazine derivatives with acetylacetone in the presence of triethylamine to produce the corresponding target products in high yield and purity. The antiproliferative activity of the novel mono- and bis(dimethylpyrazolyl)-s-triazine derivatives was studied against three cancer cell lines, namely, MCF-7, HCT-116, and HepG2. N-(4-Bromophenyl)-4-(3,5-dimethyl-1H-pyrazol-1-yl)-6-morpholino-1,3,5-triazin-2-amine 4f, N-(4-chlorophenyl)-4,6-bis(3,5-dimethyl-1H-pyrazol-1-yl)-1,3,5-triazin-2-amine 5c, and 4,6-bis(3,5-dimethy…

The $p\lambda n$ fractal decomposition: Nontrivial partitions of conserved physical quantities

2015

A mathematical method for constructing fractal curves and surfaces, termed the $p\lambda n$ fractal decomposition, is presented. It allows any function to be split into a finite set of fractal discontinuous functions whose sum is equal everywhere to the original function. Thus, the method is specially suited for constructing families of fractal objects arising from a conserved physical quantity, the decomposition yielding an exact partition of the quantity in question. Most prominent classes of examples are provided by Hamiltonians and partition functions of statistical ensembles: By using this method, any such function can be decomposed in the ordinary sum of a specified number of terms (g…

Generality of Henstock-Kurzweil type integral on a compact zero-dimensional metric space

2011

ABSTRACT A Henstock-Kurzweil type integral on a compact zero-dimensional metric space is investigated. It is compared with two Perron type integrals. It is also proved that it covers the Lebesgue integral.