Search results for "diagnostic"
showing 10 items of 8913 documents
Guía de fortalecimiento asociativo en fibrosis quística. Sistematización de la práctica asociativa. Una mirada de 360º
2018
En los últimos años, el movimiento asociativo ha evolucionado tanto en volumen como en la calidad de los servicios que ofrece. El tercer sector está dejando atrás la “caridad”, la “voluntariedad” para dar paso a la planificación de las actuaciones sociales y la profesionalización de los servicios.El colectivo de Fibrosis Quística, liderado por una federación con 30 años de recorrido cuya misión es agrupar a las asociaciones de Fibrosis Quística para mejorar la calidad de vida de las personas con FQ y sus familias, ha editado un libro que es un digno aspirante a ilustrar esta transformación: “Guía de fortalecimiento asociativo en Fibrosis Quística”. Sistematización de la práctica asociativa.…
Elementi di psicodiagnostica. Aspetti teorici e tecnici della valutazione.
2015
La scelta del titolo "elementi di psicodiagnostica" rende conto della natura processuale e complessa della valutazione clinica il cui oggetto di studio è la realtà psichica della persona nella sua unicità irripetibile. Sulla scia delle tesi più recenti viene presentato un impianto metodologico della psicodiagnostica che ha al centro l'individuo e le sue relazioni e privilegia la dimensione dell'ascolto e consente di cogliere le comunicazioni verbali e non verbali, anche mediante l'utilizzo di strumenti specifici quali ad esempio i test.
Multidimensional instruments with an integral approach to identify frailty in community-dwelling people: protocol for a systematic psychometric review
2019
IntroductionAn increasing number of investigations highlight the complex nature of frailty; therefore, the use of multidimensional assessment instruments could be useful in clinical decision-making. Frail people are found mainly in the community setting which is why this is the ideal environment for early screening and intervention. For this purpose, it is necessary to have valid, time-effective and easy-to-use frailty assessment instruments. The aim of this review is to critically appraise, compare and summarise the quality of the measurement properties of all multidimensional instruments with an integral approach to identify frailty in community-dwelling people.Methods and analysisMedline…
High-affinity and selective detection of pyrophosphate in water by a resorcinarene salt receptor
2017
N-Alkyl ammonium resorcinarenes selectively bind pyrophosphate in pure water with an exceptionally high binding constant of up to 1.60 × 107 M–1, three orders of magnitude higher than ATP.
Rac1-Regulated Endothelial Radiation Response Stimulates Extravasation and Metastasis That Can Be Blocked by HMG-CoA Reductase Inhibitors
2011
Radiotherapy (RT) plays a key role in cancer treatment. Although the benefit of ionizing radiation (IR) is well established, some findings raise the possibility that irradiation of the primary tumor not only triggers a killing response but also increases the metastatic potential of surviving tumor cells. Here we addressed the question of whether irradiation of normal cells outside of the primary tumor augments metastasis by stimulating the extravasation of circulating tumor cells. We show that IR exposure of human endothelial cells (EC), tumor cells (TC) or both increases TC-EC adhesion in vitro. IR-stimulated TC-EC adhesion was blocked by the HMG-CoA reductase inhibitor lovastatin. Glycyrr…
Radiolabeling of Nanoparticles and Polymers for PET Imaging
2014
Nanomedicine has become an emerging field in imaging and therapy of malignancies. Nanodimensional drug delivery systems have already been used in the clinic, as carriers for sensitive chemotherapeutics or highly toxic substances. In addition, those nanodimensional structures are further able to carry and deliver radionuclides. In the development process, non-invasive imaging by means of positron emission tomography (PET) represents an ideal tool for investigations of pharmacological profiles and to find the optimal nanodimensional architecture of the aimed-at drug delivery system. Furthermore, in a personalized therapy approach, molecular imaging modalities are essential for patient screeni…
Mi descrivi il tuo disegno del Mattoncino Lego? Un’esperienza didattica di matematica nella scuola dell’infanzia
2018
La consapevolezza dell’importanza di guardare, attraverso una lente di tipo matematico, i disegni prodotti dai bambini, considerandoli come strumento diagnostico per quello che D’Amore et al. (2004) chiamano come il “Campo di Esperienza” Spazio, Ordine e Misura, ha dato spunto a questo contributo che discute una sperimentazione didattica condotta in una sezione di scuola dell’infanzia (5 anni). All’interno della stessa è stato chiesto ai bambini di rappresentare dei mattoncini Lego con un disegno, e di descrivere successivamente i propri elaborati rintracciando e argomentando in essi eventuali segni di scarto numerico-spaziali rispetto al mattoncino osservato/manipolato, attraverso visioni …
Kuormituskoe modernin kuvantamisen aikakaudella
2019
Kuormituskoetta käytetään sepelvaltimotaudin ja muidenkin sydänsairauksien diagnosoinnissa, ennusteen arvioinnissa, hoidon suunnittelussa ja seurannassa. Kuormituskokeen keskeisin etu on sen helppo saatavuus sekä avoterveydenhuollossa että erikoissairaanhoidossa. Rasitukseen liittyvien oireiden tai suorituskyvyn heikkenemisen yhteydessä kuormituskoe on edelleen arvokas perustutkimus. Sen käytön keskeisin rajoite liittyy sen diagnostiseen osuvuuteen, ja sepelvaltimotaudin ali- ja ylidiagnostiikan välttämiseksi kuormituskokeen käyttö tulisikin rajata liikuntakykyisiin potilaisiin, joilla taudin todennäköisyys ennen testiä on keskisuuri tai suuri. Kuormituskoe sopii potilaille, joiden lepo-EKG…
Enterobacter cloacae administration induces hepatic damage and subcutaneous fat accumulation in high-fat diet fed mice.
2018
Accumulating evidence indicates that gut microbiota plays a significant role in obesity, insulin resistance and associated liver disorders. Family Enterobacteriaceae and especially Enterobacter cloacae strain B29 have been previously linked to obesity and hepatic damage. The underlying mechanisms, however, remain unclear. Therefore, we comprehensively examined the effects of E. cloacae subsp. cloacae (ATCC® 13047™) administration on host metabolism of mice fed with high-fat diet (HFD). C57BL/6N mice were randomly divided into HFD control, chow control, and E. cloacae treatment groups. The E. cloacae treatment group received live bacterial cells in PBS intragastrically twice a week, every ot…
Structured reporting of rectal cancer staging and restaging: A consensus proposal
2021
Background: Structured reporting (SR) in oncologic imaging is becoming necessary and has recently been recognized by major scientific societies. The aim of this study was to build MRI-based structured reports for rectal cancer (RC) staging and restaging in order to provide clinicians all critical tumor information. Materials and Methods: A panel of radiologist experts in abdominal imaging, called the members of the Italian Society of Medical and Interventional Radiology, was established. The modified Delphi process was used to build the SR and to assess the level of agreement in all sections. The Cronbach’s alpha (Cα) correlation coefficient was used to assess the internal consistency of ea…