Search results for "double"
showing 10 items of 2879 documents
On W.E.B. Du Bois, Double Consciousness, and Racialized Modernity. An Interview with José Itzigsohn
2021
The February issue of Transilvania journal hosts an interview with professor José Itzigsohn focusing on his activity within the field of sociology and his latest book with Karida L. Brown, on The Sociology of W. E. B. Du Bois. Racialized Modernity and the Global Color Line (New York University Press, 2020). It delves into Du Boisian sociology, “double consciousness” and racialized modernity, alongside contemporary decolonial perspectives and new studies and researchers in the field.
Les raisons de la double activité des médecins : le cas de l'Algérie
2014
L’objet de cet article est d’analyser la double activite des medecins en Algerie sous trois angles d’approche. Le premier mobilise les theories de l’offre de travail appliquees aux professionnels de sante confrontes a l’existence de deux secteurs, un prive, un public, dont bien souvent les niveaux de remuneration horaire different et ou les temps respectifs de travail peuvent en partie etre choisis. La complementarite entre les deux emplois sous-tend dans une large mesure les strategies d’offre de travail des medecins. Le deuxieme se refere aux registres des motivations des medecins dans leur choix d’une activite privee complementaire. Le troisieme est relatif aux strategies d’adressage des…
There’s a Double Tongue in Cheek: On the Un(Translatability) of Shakespeare’s Bawdy Puns into Romanian
2017
AbstractThe translatability of William Shakespeare’s titillating puns has been a topic of recurrent debate in the field of translation studies, with some scholars arguing that they are untranslatable and others maintaining that such an endeavour implies a divorce from formal equivalence. Romanian translators have not troubled themselves with settling this dispute, focusing instead on recreating them as bawdily and punningly as possible in their first language. At least, this is the conclusion to which George Volceanov has come after analysing a sample of Shakespearean ribald puns and their Romanian equivalents. By drawing parallels between such instances of the Bard’s rhetoric and three of …
Numerical and Experimentical Study of Motion Control Using Pressure Feedback
2013
This paper is concerned with the inherent oscillatory nature of pressure compensated motion control of a hydraulic cylinder subjected to a negative load and suspended by means of an overcenter valve. A pressure feedback scheme that indirectly eliminates the oscillations is investigated. The indirect control scheme utilizes pressure feedback to electronically compensate the metering-out allowing for the removal of the compensator and, subsequently, elimination of the oscillations. The suggested electronic compensation scheme is implemented and examined in a single degree-of-freedom test rig actuated by means of a double acting hydraulic cylinder. The control scheme is compared with other con…
Randomized placebo-controlled trial comparing fluticasone aqueous nasal spray in mono-therapy, fluticasone plus cetirizine, fluticasone plus monteluk…
2004
BACKGROUND: Corticosteroids are considered to be particularly effective in reducing nasal congestion and are therefore recommended as first-line treatment in allergic rhinitis patients with moderate to severe and/or persistent symptoms. OBJECTIVE: We compared the clinical efficacy of fluticasone propionate aqueous nasal spray (FPANS) 200 microg given once daily, administered in mono-therapy or combined therapy with a H1 receptor antagonist (cetirizine, CTZ) or with a leukotriene antagonist (montelukast, MSK), and the combined therapy of CTZ plus MSK in the treatment of patients affected by allergic rhinitis to Parietaria during natural pollen exposure. In addition, we examined the effect of…
Impact des allocations en ressources sur l'efficacité des écoles primaires en Côte d'Ivoire
2011
The quality of primary education in Côte d'Ivoire has deteriorated sharply over the past three decades. This situation is the result of an approximate management of the education system, which is characterized by a lack of educational support, a misallocation of resources, a congestion of classrooms (42 students for a teacher in primary school) and a lack of skilled and well trained teachers. In addition, the military-political conflict in September 2002 did not allow to improve this situation; on the contrary, it has further deteriorated the situation. Thus, the aim of this thesis is first to analyze the influence of resource endowments on the effectiveness of primary schools in Cote d'Ivo…
Pulsed electromagnetic field therapy in the treatment of pain and other symptoms in fibromyalgia : a randomized controlled study
2018
Low-energy pulsed electromagnetic field (PEMF) therapy has been suggested as a promising therapy to increase microcirculation, which is of great concern in patients with fibromyalgia. This study evaluated the effectiveness of PEMF therapy on the treatment of fibromyalgia. A group of 108 women with fibromyalgia were allocated to a 12-week treatment period with an active Bio-Electro-Magnetic-Energy-Regulation (BEMER) device and a similar treatment period with an inactive device. Each patient received active and sham treatments in a random order. Pain and stiffness were assessed on a visual analog scale (VAS, scale 0-100mm), and functional status was assessed by the Fibromyalgia Impact Questio…
Compromised repair of radiation-induced DNA double-strand breaks in Fanconi anemia fibroblasts in G2
2020
Fanconi anemia (FA) is a rare chromosomal instability syndrome with various clinical features and high cancer incidence. Despite being a DNA repair disorder syndrome and a frequently observed clinical hypersensitivity of FA patients towards ionizing radiation, the experimental evidence regarding the efficiency of radiation-induced DNA double-strand break (DSB) repair in FA is very controversial. Here, we performed a thorough analysis of the repair of radiation-induced DSBs in G1 and G2 in FA fibroblasts of complementation groups A, C, D1 (BRCA2), D2, E, F, G and P (SLX4) in comparison to normal human lung and skin fibroblasts. γH2AX, 53BP1, or RPA foci quantification after X-irradiation was…
Targeting components of the alternative NHEJ pathway sensitizes KRAS mutant leukemic cells to chemotherapy.
2014
Abstract Activating KRAS mutations are detected in a substantial number of hematologic malignancies. In a murine T-cell acute lymphoblastic leukemia (T-ALL) model, we previously showed that expression of oncogenic Kras induced a premalignant state accompanied with an arrest in T-cell differentiation and acquisition of somatic Notch1 mutations. These findings prompted us to investigate whether the expression of oncogenic KRAS directly affects DNA damage repair. Applying divergent, but complementary, genetic approaches, we demonstrate that the expression of KRAS mutants is associated with increased expression of DNA ligase 3α, poly(ADP-ribose) polymerase 1 (PARP1), and X-ray repair cross-comp…
Processing of O6-methylguanine into DNA double-strand breaks requires two rounds of replication whereas apoptosis is also induced in subsequent cell …
2009
The DNA adduct O(6)-methylguanine (O(6)MeG) induced by environmental genotoxins and anticancer drugs is a highly mutagenic, genotoxic and apoptotic lesion. Apoptosis induced by O(6)MeG requires mismatch repair (MMR) and proliferation. Models of O(6)MeG-triggered cell death postulate that O(6)MeG/T mispairs activate MMR giving rise to either direct genotoxic signaling or secondary lesions that trigger apoptotic signaling in the 2(nd) replication cycle. To test these hypotheses, we used a highly synchronized cell system competent and deficient for the repair of O(6)MeG adducts, which were induced by the S(N)1 methylating agent N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). We show that DNA doub…