Search results for "eps"
showing 10 items of 1777 documents
Phenazine antibiotics produced by fluorescent pseudomonads contribute to natural soil suppressiveness to Fusarium wilt
2009
Natural disease-suppressive soils provide an untapped resource for the discovery of novel beneficial microorganisms and traits. For most suppressive soils, however, the consortia of microorganisms and mechanisms involved in pathogen control are unknown. To date, soil suppressiveness to Fusarium wilt disease has been ascribed to carbon and iron competition between pathogenic Fusarium oxysporum and resident non-pathogenic F. oxysporum and fluorescent pseudomonads. In this study, the role of bacterial antibiosis in Fusarium wilt suppressiveness was assessed by comparing the densities, diversity and activity of fluorescent Pseudomonas species producing 2,4-diacetylphloroglucinol (DAPG) (phlD+) …
Circular RNAs in Sepsis: Biogenesis, Function, and Clinical Significance
2020
Sepsis is a life-threatening condition that occurs when the body responds to an infection that damages it is own tissues. The major problem in sepsis is rapid, vital status deterioration in patients, which can progress to septic shock with multiple organ failure if not properly treated. As there are no specific treatments, early diagnosis is mandatory to reduce high mortality. Despite more than 170 different biomarkers being postulated, early sepsis diagnosis and prognosis remain a challenge for clinicians. Recent findings propose that circular RNAs (circRNAs) may play a prominent role in regulating the patients’ immune system against different pathogens, including bacteria and viruses. Mou…
Etude du coaching d’un directeur de recherche de l’INRAE. Soutenu publiquement le 9 janvier 2023. Diplôme d’Université « Coaching & Management ». Par…
2023
The world of public research seems at first sight to be very little concerned by themanagement issues of the business world in which the right decisions must be taken and forwhich there is an obligation to perform. The very idea of coaching researchers seemsincongruous. The purpose of this study is to challenge this idea, by describing precisely whatthe profession of researcher is in the world of public research - their belonging to very complexstructures and the demanding challenges they have to face - then by studying thecontributions of cognitive-behavioural coaching methodologies. The analysis of the practiceshows that coaching based on constructivist psychology can lead to a better pra…
One-Dimensional Convolutional Neural Networks Combined with Channel Selection Strategy for Seizure Prediction Using Long-Term Intracranial EEG
2022
Seizure prediction using intracranial electroencephalogram (iEEG) has attracted an increasing attention during recent years. iEEG signals are commonly recorded in the form of multiple channels. Many previous studies generally used the iEEG signals of all channels to predict seizures, ignoring the consideration of channel selection. In this study, a method of one-dimensional convolutional neural networks (1D-CNN) combined with channel selection strategy was proposed for seizure prediction. First, we used 30-s sliding windows to segment the raw iEEG signals. Then, the 30-s iEEG segments, which were in three channel forms (single channel, channels only from seizure onset or free zone and all c…
One and Two Dimensional Convolutional Neural Networks for Seizure Detection Using EEG Signals
2021
Deep learning for the automated detection of epileptic seizures has received much attention during recent years. In this work, one dimensional convolutional neural network (1D-CNN) and two dimensional convolutional neural network (2D-CNN) are simultaneously used on electroencephalogram (EEG) data for seizure detection. Firstly, using sliding windows without overlap on raw EEG to obtain the definite one-dimension time EEG segments (1D-T), and continuous wavelet transform (CWT) for 1D-T signals to obtain the two-dimension time-frequency representations (2D-TF). Then, 1D-CNN and 2D-CNN model architectures are used on 1D-T and 2D-TF signals for automatic classification, respectively. Finally, t…
A new member of the fusaricidin family – structure elucidation and synthesis of fusaricidin E
2017
Two hitherto unknown fusaricidins were obtained from fermentation broths of three Paenibacillus strains. After structure elucidation based on tandem mass spectrometry and NMR spectroscopy, fusaricidin E was synthesized to confirm the structure and the suggested stereochemistry. The synthesis was based on a new strategy which includes an efficient access to the 15-guanidino-3-hydroxypentadecanoyl (GHPD) side chain from erucamide.
Nuove soluzioni e vecchie problematiche con riferimento al problema della tassazione delle imprese digitali
2022
Il contributo analizza il diverso approccio che negli studi domestici ed internazionali è stato utilizzato per affrontare il tema della tassazione dell'economia digitale: per un verso il cd. ring-fencing e cioè il tentativo di trovare soluzioni impositive specifiche e mirate alle peculiarità del fenomeno e, per altro verso, quello di considerare l'economia digitale al pari delle tradizionali forme economiche. In tale contesto, dopo aver analizzato i più diffusi fenomeni di base erosion and profit shifting (BEPS) posti in essere principalmente dalle multinazionali dell'economia digitale, il contributo analizza le soluzioni che sono state proposte per arginare il fenomeno in campo internazion…
Examinations of Bilateral Epileptiform Activities in Hippocampal Slices Obtained From Young Mice
2021
Bilateral interconnections through the hippocampal commissure play important roles in synchronizing or spreading hippocampal seizure activities. Intact hippocampi or bilateral hippocampal slices have been isolated from neonatal or immature rats (6–7 or 12–21 days old, respectively) and the mechanisms underlying the bilateral synchrony of hippocampal epileptiform activities have been investigated. However, the feasibility of examining bilateral epileptiform activities of more developed hippocampal circuitryin vitroremains to be explored. For this, we prepared bilateral hippocampal slices from C57 black mice, a strain commonly used in neuroscience and for genetic/molecular modifications. Youn…
Informaation piilottaminen draamasarjassa Lost
2018
Tarkastelen tässä tutkielmassa Lost-draamasarjassa (USA 2004–2010) esiintyvää informaation piilottamista. Esittelen sarjasta poimimieni esimerkkien avulla niitä kerronnan keinoja, joiden avulla sarja viivyttää tiedon paljastamista katsojalle. Pohdin myös piilottamisen ongelmia sekä etuja. In this thesis I examine the hiding of information in the drama series Lost (USA 2004–2010). With examples from Lost I explain the narrative devices used in the series to delay the disclosure of information. I also contemplate the pros and cons of such hiding.
Consistent phenological shifts in the making of a biodiversity hotspot: the Cape flora
2011
Abstract Background The best documented survival responses of organisms to past climate change on short (glacial-interglacial) timescales are distributional shifts. Despite ample evidence on such timescales for local adaptations of populations at specific sites, the long-term impacts of such changes on evolutionary significant units in response to past climatic change have been little documented. Here we use phylogenies to reconstruct changes in distribution and flowering ecology of the Cape flora - South Africa's biodiversity hotspot - through a period of past (Neogene and Quaternary) changes in the seasonality of rainfall over a timescale of several million years. Results Forty-three dist…