Search results for "functional"

showing 10 items of 4822 documents

Reductive transformations - 11. stereoselective cycloannelation and bridging of the cyclooctatetraene dianionMakromol. Chem., Rapid. Commun. 1988, 9,…

1988

Abstract Bifunctional electrophiles with C4-, C6-, and C8-chains are reacted with the cyclooctatetraene dianion to selectively give novel cycloannelation and bridging products which possess a surprising stereochemistry and are useful starting compounds for further syntheses.

chemistry.chemical_classificationAnnulationStereochemistryOrganic ChemistryHalocarbonBiochemistrychemistry.chemical_compoundCyclooctatetraenePolycyclic compoundchemistryDrug DiscoveryElectrophileStereoselectivityBifunctionalAliphatic compoundTetrahedron Letters
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2,4,5-Trimethylimidazolium Scaffold for Anion Recognition Receptors Acting Through Charge-Assisted Aliphatic and Aromatic C–H Interactions

2016

A series of two-armed 2,4,5-trimethylimidazolium-based oxoanion receptors, which incorporate two end-capped photoactive anthracene rings, being the central core an aromatic or heteroaromatic ring, has been designed. In the presence of HP2O7(3-), H2PO4(-), and SO4(2-) anions, (1)H- and (31)P NMR spectroscopical data clearly indicate the simultaneous occurrence of several charge-assisted aliphatic and aromatic C-H noncovalent interactions, i.e., significant downfield shifts were observed for the imidazolium C(2)-CH3 protons, the methylene N-CH2 protons, and the inner aromatic proton or the outer heteroaromatic protons. Density functional theory calculations confirm the occurrence of these non…

chemistry.chemical_classificationAnthraceneProton010405 organic chemistryStereochemistryOrganic ChemistryNuclear magnetic resonance spectroscopy010402 general chemistryRing (chemistry)01 natural sciences0104 chemical sciences3. Good healthIonCrystallographychemistry.chemical_compoundchemistryNon-covalent interactionsDensity functional theoryMethyleneThe Journal of Organic Chemistry
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On the origin of functionalization in one-pot radiation synthesis of nanogels from aqueous polymer solutions

2016

Radiation-engineered poly(N-vinyl pyrrolidone) nanogels are very interesting biocompatible nanocarriers for i.v. administration of therapeutics and contrast agents for bioimaging. The manufacturing process is fast and effective, it grants excellent control of particle size and simultaneous sterilization of the formed nanogels. Interestingly, primary amino groups and carboxyl groups, useful for (bio)conjugation, are also formed in a dose-dependent fashion. In this paper, by means of both numerical simulations and experiments, the origin of nanogel size control and functionalization is investigated. This understanding offers a new dimension for the design and production of radiation-sculpture…

chemistry.chemical_classificationAqueous solutionirradiationManufacturing processGeneral Chemical EngineeringNanotechnology02 engineering and technologyGeneral ChemistryPolymerradiation-sculptured multifunctional nanocarriers from aqueous solutions of polymers010402 general chemistry021001 nanoscience & nanotechnologyBiocompatible material01 natural sciences0104 chemical scienceschemistrySurface modificationSettore CHIM/07 - Fondamenti Chimici Delle TecnologieParticle sizeNanocarriers0210 nano-technologyhydrogelsNanogel
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A detailed MSn study for the molecular identification of a dimer formed from oxidation of pinene

2016

Abstract Dimeric products formed in the oxidation of α- and β-pinene have been frequently observed in laboratory and field studies of biogenic SOA formation. While their existence is undoubted, their exact chemical structures remain unclear. This study uses a combined two step approach aiming on the molecular identification of the most important of the various dimers that have been observed in biogenic secondary organic aerosol formation, a dimer with the molecular weight 358 g mol−1. The first step is the application of a functional group derivatization technique (esterification) to quantify the number of carboxylic acid groups in the target molecule. Based on the detailed interpretation o…

chemistry.chemical_classificationAtmospheric Science010504 meteorology & atmospheric sciencesDimerCarboxylic acid010501 environmental sciencesMass spectrometry01 natural scienceschemistry.chemical_compoundchemistryFragmentation (mass spectrometry)Computational chemistryReagentFunctional groupOrganic chemistryMoleculeDerivatization0105 earth and related environmental sciencesGeneral Environmental ScienceAtmospheric Environment
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Thermodynamic properties and cloud droplet activation of a series of oxo-acids

2010

Abstract. We have investigated the thermodynamic properties of four aliphatic oxo-dicarboyxlic acids identified or thought to be present in atmospheric particulate matter: oxosuccinic acid, 2-oxoglutaric acid, 3-oxoglutaric acid, and 4-oxopimelic acid. The compounds were characterized in terms of their cloud condensation nuclei (CCN) activity, vapor pressure, density, and tendency to decarboxylate in aqueous solution. We deployed a variety of experimental techniques and instruments: a CCN counter, a Tandem Differential Mobililty Analyzer (TDMA) coupled with a laminar flow-tube, and liquid chromatography/mass spectrometry (LC/MS). The presence of the oxo functional group in the α-position ca…

chemistry.chemical_classificationAtmospheric ScienceAqueous solutionTandemVapor pressureInorganic chemistryParticulatesMass spectrometrylcsh:QC1-999lcsh:Chemistrychemistry.chemical_compoundDicarboxylic acidchemistrylcsh:QD1-999Functional groupOrganic chemistryCloud condensation nucleilcsh:PhysicsAtmospheric Chemistry and Physics
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3'-Arylazido-beta-alanyl-2-azido ATP, a cross-linking photoaffinity label for F1ATPases.

1989

Abstract The synthesis of the 3′-arylazido-2-azido ATP derivative 3′-O-{3-[N-(4-azido-2-nitrophenyl)-amino]propionyl}2-azido-adenosine 5′-triphosphate (2,3′-DiN3ATP) is described. The bifunc­ tional photoreactive ATP analog is characterized spectroscopically. Photoaffinity labeling of F, ATPase from Micrococcus luteus by this analog results in the inactivation of the enzyme and in the formation of higher molecular weight cross-links,

chemistry.chemical_classificationAzidesPhotoaffinity labelingbiologyLightStereochemistryAffinity Labelsbiology.organism_classificationGeneral Biochemistry Genetics and Molecular BiologyMicrococcuschemistry.chemical_compoundKineticsProton-Translocating ATPasesEnzymeAdenosine TriphosphatechemistryIndicators and ReagentsBifunctionalBeta (finance)Micrococcus luteusDerivative (chemistry)Zeitschrift fur Naturforschung. C, Journal of biosciences
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On-Surface Synthesis of Oligo(indenoindene)

2020

Fully conjugated ladder polymers (CLP) possess unique optical and electronic properties, and are considered promis-ing materials for applications in (opto)electronic devices. Poly(indenoindene) is a CLP consisting of an alternating array of five- and six-membered rings, which has remained elusive so far. Here, we report an on-surface synthesis of oligo(indenoindene) on Au(111). Its structure and a low elec-tronic bandgap have been elucidated by low-temperature scanning tunneling microscopy and spectroscopy and non-contact atomic force microscopy, complemented by density functional theory calculations. Achieving defect-free seg-ments of oligo(indenoindene) offers an exclusive insight into th…

chemistry.chemical_classificationBand gapAtomic force microscopy530 PhysicsElectronic bandNanotechnologyGeneral ChemistryPolymerConjugated system010402 general chemistry01 natural sciencesBiochemistryCatalysis0104 chemical scienceslaw.inventionColloid and Surface Chemistrychemistrylaw540 ChemistryDensity functional theoryScanning tunneling microscopeSpectroscopy
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Simulation and theory of fluid demixing and interfacial tension of mixtures of colloids and nonideal polymers.

2005

An extension of the Asakura-Oosawa-Vrij model of hard sphere colloids and non-adsorbing polymers, that takes polymer non-ideality into account through a repulsive stepfunction pair potential between polymers, is studied with grand canonical Monte Carlo simulations and density functional theory. Simulation results validate previous theoretical findings for the shift of the bulk fluid demixing binodal upon increasing strength of polymer-polymer repulsion, promoting the tendency to mix. For increasing strength of the polymer-polymer repulsion, simulation and theory consistently predict the interfacial tension of the free colloidal liquid-gas interface to decrease significantly for fixed colloi…

chemistry.chemical_classificationBinodalQuantitative Biology::BiomoleculesMaterials scienceThermodynamicsFOS: Physical sciencesPolymerCondensed Matter - Soft Condensed MatterAtomic packing factorSurface tensionCondensed Matter::Soft Condensed MatterColloidchemistrySoft Condensed Matter (cond-mat.soft)Density functional theoryPair potentialGrand canonical monte carloPhysical review. E, Statistical, nonlinear, and soft matter physics
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Catalytic Diastereo- and Enantioselective Synthesis of 2-Imidazolinones.

2019

Chiral cyclic ureas (2-imidazolinones) were prepared by the reaction of nitrones and isocyanoacetate esters using a multicatalytic system that combines a bifunctional Brønsted base-squaramide organocatalyst and Ag+ as a Lewis acid. The reaction could be achieved with a range of nitrones derived from aryl- and cycloalkylaldehydes with moderate diastereo- and good enantioselectivity. A plausible mechanism involving an initial formal [3 + 3] cycloaddition of the nitrone and isocyanoacetate ester, followed by rearrangement to an aminoisocyanate and cyclization to the imidazolinone, is proposed.

chemistry.chemical_classificationChemistryArylOrganic ChemistryEnantioselective synthesisBiochemistryCombinatorial chemistryCycloadditionCatalysisNitronechemistry.chemical_compoundCatàlisiLewis acids and basesPhysical and Theoretical ChemistryBifunctionalQuímica orgànicaOrganic letters
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Understanding Noncovalent Interactions of Small Molecules with Carbon Nanotubes

2017

We combine experimental methods, density functional theory (DFT) calculations, and molecular dynamics (MD) simulations in the quantitative analysis of noncovalent interactions between (6,5)-enriched single-walled carbon nanotubes (SWNTs), as hosts, and a set of pyrene derivatives with different electronic properties and surface areas, as guests. The experiments and calculations were carried out in two solvents with markedly different polarities, namely 1,1',2,2'-tetrachloroethane (TCE) and N,N-dimethylformamide (DMF). Our results show that dispersion forces govern the supramolecular association of small molecules with (6,5)-SWNTs, with negligible contributions from ground-state charge-trans…

chemistry.chemical_classificationChemistryOrganic ChemistrySupramolecular chemistrySolvation02 engineering and technologyGeneral ChemistryCarbon nanotube010402 general chemistry021001 nanoscience & nanotechnology01 natural sciencesTetrachloroethaneLondon dispersion forceCatalysis0104 chemical scienceslaw.inventionMolecular dynamicsComputational chemistrylawNon-covalent interactionsDensity functional theory0210 nano-technology
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