Search results for "goals"
showing 10 items of 643 documents
Integrating Virtual Realities and Psychotherapy: SWOT Analysis on VR and MR Based Treatments of Anxiety and Stress-related Disorders
2021
© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.The use of virtual reality (VR) and mixed reality (MR) technology in clinical psychology is growing. Efficacious VR-based treatments for a variety of disorders have been developed. However, the field of technology-assisted psychotherapy is constantly changing with the advancement in technology. Factors such as interdisciplinary collaboration, consumer familiarity and adoption of VR products, and progress in clinical science all need to be taken into consideration when integrating virtual technologies into psychotherapies. We aim to present an overview of current expert opinions on the use of virtual…
Rethinking science communication in a changing landscape
2021
Science communication continues to grow, develop and change, as a practice and field of research. The boundaries between science and the rest of society are blurring. Digitalization transforms the public sphere. This JCOM special issue aims to rethink science communication in light of the changing science communication landscape. How to characterize the emerging science communication ecosystem in relation to the introduction of new media and actors involved? What new practices are emerging? How is the quality of science communication maintained or improved? We present a selection of papers that provide different perspectives on these questions and challenges.
Chronic physical conditions, physical multimorbidity, and quality of life among adults aged ≥ 50 years from six low- and middle-income countries
2022
Abstract Purpose Multimorbidity (i.e., ≥ 2 chronic conditions) poses a challenge for health systems and governments, globally. Several studies have found inverse associations between multimorbidity and quality of life (QoL). However, there is a paucity of studies from low- and middle-income countries (LMICs), especially among the older population, as well as studies examining mediating factors in this association. Thus, the present study aimed to explore the associations, and mediating factors, between multimorbidity and QoL among older adults in LMICs. Methods Cross-sectional nationally representative data from the Study on Global Ageing and Adult Health were analyzed. A total of 11 chroni…
Measurement of the chi(b) (3 P) mass and of the relative rate of chi(b1) (1 P) and chi(b2) (1 P) production
2014
The production of $\chi_b$ mesons in proton-proton collisions is studied using a data sample collected by the LHCb detector, at centre-of-mass energies of $\sqrt{s}=7$ and $8$ TeV and corresponding to an integrated luminosity of 3.0 fb$^{-1}$. The $\chi_b$ mesons are identified through their decays to $\Upsilon(1S)\gamma$ and $\Upsilon(2S)\gamma$ using photons that converted to $e^+e^-$ pairs in the detector. The $\chi_b(3P)$ meson mass, and the relative prompt production rate of $\chi_{b1}(1P)$ and $\chi_{b2}(1P)$ mesons as a function of the $\Upsilon(1S)$ transverse momentum in the $\chi_b$ rapidity range 2.0< $y$<4.5, are measured. Assuming a mass splitting between the $\chi_{b1}(3P)$ an…
First measurement of the charge asymmetry in beauty-quark pair production.
2014
The difference in the angular distributions between beauty quarks and antiquarks, referred to as the charge asymmetry, is measured for the first time in b[bar over b] pair production at a hadron collider. The data used correspond to an integrated luminosity of 1.0 fb[superscript −1] collected at 7 TeV center-of-mass energy in proton-proton collisions with the LHCb detector. The measurement is performed in three regions of the invariant mass of the b[bar over b] system. The results obtained are A[b[bar over b] over C](40 105 GeV/c[superscript 2]) = 1.6 ± 1.7 ± 0.6%, where A[b[bar over b] over C] is defined as the asymmetry in the difference in rapidity between jets formed from the beauty q…
AGuIX® from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine.
2019
International audience; AGuIX® are sub-5 nm nanoparticles made of a polysiloxane matrix and gadolinium chelates. This nanoparticle has been recently accepted in clinical trials in association with radiotherapy. This review will summarize the principal preclinical results that have led to first in man administration. No evidence of toxicity has been observed during regulatory toxicity tests on two animal species (rodents and monkeys). Biodistributions on different animal models have shown passive uptake in tumours due to enhanced permeability and retention effect combined with renal elimination of the nanoparticles after intravenous administration. High radiosensitizing effect has been obser…
The use of theranostic gadolinium-based nanoprobes to improve radiotherapy efficacy
2014
International audience; A new efficient type of gadolinium-based theranostic agent (AGuIX) has recently been developed for magnetic resonance imaging (MRI)-guided radiotherapy. These new particles consist of a polysiloxane network surrounded by a number of gadolinium chelates, usually 10. Due to their small size (<5 nm), AGuIX typically exhibit biodistributions that are almost ideal for diagnostic and therapeutic purposes. For example, while a significant proportion of these particles accumulate in tumours, the remainder is rapidly eliminated by the renal route. In addition, these particles present no evidence of toxicity, in the absence of irradiation with up to 10 times the planned dose f…
Troponin I and cardiovascular risk prediction in the general population: the BiomarCaRE consortium
2016
AIMS: Our aims were to evaluate the distribution of troponin I concentrations in population cohorts across Europe, to characterize the association with cardiovascular outcomes, to determine the predictive value beyond the variables used in the ESC SCORE, to test a potentially clinically relevant cut-off value, and to evaluate the improved eligibility for statin therapy based on elevated troponin I concentrations retrospectively.METHODS AND RESULTS: Based on the Biomarkers for Cardiovascular Risk Assessment in Europe (BiomarCaRE) project, we analysed individual level data from 10 prospective population-based studies including 74 738 participants. We investigated the value of adding troponin …
Renewable energy for sustainable rural development: synergies and mismatches
2020
Abstract Energy transition is increasingly regarded as a promising opportunity for the economic development of rural areas. This possibility is associated with the siting and (co-)ownership of decentralized (small-scale) renewable energy facilities. The underlying productive link, however, has been taken for granted, rather than conceptually and practically cultivated. Thus, while renewable energy-based rural development has been stated as a desired by-product of energy transitions, its potential has remained largely unfulfilled. This review aims to illuminate the ambiguous interplay between renewable energy and rural development in the context of the current trajectories of the energy tran…
Utilizing Experience Goals in Design of Industrial Systems
2017
The core idea of experience-driven design is to define the intended experience before functionality and technology. This is a radical idea for companies that have built their competences around specific technologies. Although many technology companies are willing to shift their focus towards experience-driven design, reports on real-life cases about the utilization of this design approach are rare. As part of an industry-led research program, we introduced experience-driven design to metal industry companies with experience goals as the key technique. Four design cases in three companies showed that the goals are useful in keeping the focus on user experience, but several challenges are sti…